omeprazole has been researched along with Osteoporosis in 9 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoporosis was modeled in rats by chronic (6 months) treatment with omeprazole or serotonin, and bone tissue status was studied in experimental hepatic fibrosis and during serotonin treatment under conditions of hepatic fibrosis." | 3.80 | Experimental osteoporosis and its correction. ( Golubev, YY; Golubeva, GY; Lychkov, AE; Melent'ev, AS; Petrakov, AV; Puzikov, AM; Yarygin, VN, 2014) |
| "Osteoporosis is simulated in rats by chronic administration of omeprazole or serotonin for 6 months; investigated bone status in the model of liver fibrosis and the administration of serotonin against liver fibrosis." | 3.80 | [Osteoporosis correction in experiment]. ( Puzikov, AM, 2014) |
| "Omeprazole treatment exerts its effects mostly on bone mineralization and cancellous bone, adversely affecting bone properties." | 1.39 | Can 2-oxoglutarate prevent changes in bone evoked by omeprazole? ( Bienko, M; Dobrowolski, P; Pierzynowski, SG; Radzki, RP; Tomaszewska, E; Wydrych, J; Zdybel, A, 2013) |
| "Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors." | 1.31 | Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, AL | 1 |
| Black, MH | 1 |
| Zhang, JL | 1 |
| Shi, JM | 1 |
| Jacobsen, SJ | 1 |
| Petrakov, AV | 2 |
| Yarygin, VN | 1 |
| Lychkov, AE | 1 |
| Golubev, YY | 1 |
| Puzikov, AM | 2 |
| Golubeva, GY | 1 |
| Melent'ev, AS | 1 |
| Lychkova, AE | 1 |
| Khomeriki, SG | 1 |
| Messinger-Rapport, BJ | 1 |
| Morley, JE | 1 |
| Thomas, DR | 1 |
| Gammack, JK | 1 |
| Brandt, NJ | 1 |
| Stefanacci, RG | 1 |
| Dobrowolski, P | 1 |
| Tomaszewska, E | 1 |
| Radzki, RP | 1 |
| Bienko, M | 1 |
| Wydrych, J | 1 |
| Zdybel, A | 1 |
| Pierzynowski, SG | 1 |
| Prasad, R | 1 |
| De Silva, M | 1 |
| O'Connell, MB | 1 |
| Madden, DM | 1 |
| Murray, AM | 1 |
| Heaney, RP | 1 |
| Kerzner, LJ | 1 |
1 trial available for omeprazole and Osteoporosis
| Article | Year |
|---|---|
Effects of proton pump inhibitors on calcium carbonate absorption in women: a randomized crossover trial.
Topics: Absorption; Administration, Oral; Aged; Aged, 80 and over; Antacids; Calcium Carbonate; Calcium Radi | 2005 |
8 other studies available for omeprazole and Osteoporosis
| Article | Year |
|---|---|
Proton-pump inhibitor use and hip fractures in men: a population-based case-control study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; California; Case-Control Studies; | 2014 |
Experimental osteoporosis and its correction.
Topics: Albumins; Alkaline Phosphatase; Animals; Bone and Bones; Bone Density; Calcium; Carbon Tetrachloride | 2014 |
[Osteoporosis correction in experiment].
Topics: Allografts; Animals; Anti-Ulcer Agents; Bone Density Conservation Agents; Disease Models, Animal; Fe | 2014 |
[Modeling osteoporosis].
Topics: Animals; Bone and Bones; Disease Models, Animal; Female; Omeprazole; Osteoporosis; Ovariectomy; Prot | 2010 |
Clinical update on nursing home medicine: 2011.
Topics: Anti-Ulcer Agents; Anticoagulants; Atrial Fibrillation; Clopidogrel; Clostridioides difficile; Delir | 2011 |
Discontinuation of unnecessary medications in older adults.
Topics: Aged; Aged, 80 and over; Alendronate; Anti-Ulcer Agents; Antihypertensive Agents; Assisted Living Fa | 2011 |
Can 2-oxoglutarate prevent changes in bone evoked by omeprazole?
Topics: Animals; Anti-Ulcer Agents; Biomechanical Phenomena; Bone and Bones; Bone Density; Calcification, Ph | 2013 |
Osteoporosis with underlying connective tissue disease: an unusual case.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant | 2002 |