Page last updated: 2024-08-25

methotrexate and Osteoporosis

methotrexate has been researched along with Osteoporosis in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (18.18)	18.7374
1990's	8 (12.12)	18.2507
2000's	22 (33.33)	29.6817
2010's	18 (27.27)	24.3611
2020's	6 (9.09)	2.80

Authors

Authors	Studies
Amling, M; Beil, FT; Kötter, I; Krusche, M; Rolvien, T; Ruffer, N	1
Amano, K; Iida, S; Kogo, M; Sugauchi, A; Yamada, C	1
Mönig, H; Ullrich, S	1
Albert, JD; Bart, G; Cadiou, S; Coiffier, G; Guggenbuhl, P; Robin, F	1
Chen, M; Chen, ZY; Cui, R; Dai, SM; Tong, Q	1
Hellmich, B	1
Kato, H; Nakamura, Y; Suzuki, T; Yamazaki, H; Yoshida, T	1
Fujibayashi, S; Furu, M; Hashimoto, M; Ito, H; Lyman, S; Masamoto, K; Matsuda, S; Mimori, T; Otsuki, B; Shima, K; Tanaka, M; Tanida, S; Yoshitomi, H	1
Iversen, DS; Keller, KK; Lorenzen, T; Østgård, RD	1
Bettili, F; Fracassi, E; Gatti, D; Ghellere, F; Giollo, A; Idolazzi, L; Rossini, M; Viapiana, O	1
Baggott, JE; Morgan, SL	1
Aftab, MT; Hassali, MA; Naqvi, AA	1
Aguado, P; Carrascosa, JM; Daudén, E; Muñoz-Torres, M; Rivera, R	1
Lems, WF	1
Adams, L; Alsalleeh, F; Bavitz, B; Keippel, J	1
Lustberg, MB; Oostra, DR; Pan, X; Reinbolt, RE; Shapiro, CL; Wesolowski, R	1
Chen, Y; Cui, L; Cui, Y; Gao, X; Liu, Y; Su, Y	1
Adami, G; Adami, S; Gatti, D; Idolazzi, L; Orsolini, G; Rossini, M; Viapiana, O	1
Engelage, AH; Posthuma, BJ; van der Bijl, AE; van Veen, GJ; Zijlstra, TR	1
Tanaka, Y	2
Conaghan, PG; Emery, P; Haugeberg, G; Quinn, M	1
Ferraresi, V; Prencipe, U; Salducca, N; Zoccali, C	1
Ali Ou Alla, S; Allali, F; Hajjaj-Hassouni, N	1
Bertorello, N; Corrias, A; Fagioli, F; Galletto, C; Manicone, R; Mussa, A; Nicolosi, MG; Porta, F	1
Friesenbichler, J; Leithner, A; Obermayer-Pietsch, B; Pirker-Frühauf, UM; Urban, EC	1
Kim, A; Lane, JM; Paul, J; Ricciardi, BF; Russell, LA	1
Bakker, MF; Bijlsma, JW; Jacobs, JW; Jurgens, MS; van der Goes, MC; van der Veen, MJ; van der Werf, JH; Welsing, PM	1
Leśniewski-Kmak, K; Szczylik, C; Zieliński, KW	1
Beglinger, Ch	1
Gentelle, S; Grasland, A; Paycha, F; Pouchot, J; Rudler, M; Vinceneux, P	1
Darlington, LG; Forrest, CM; Kennedy, A; Stone, TW; Stoy, N	1
Adami, S; Bianchi, G; Broggini, M; Caminiti, M; Canesi, B; di Matteo, L; di Munno, O; la Corte, R; Mazzantini, M; Minisola, G; Muratore, M; Sinigaglia, L	1
Fath, R	1
Arai, K; Endo, N; Fujisawa, J; Hanyu, T; Kondo, N; Murai, T; Nakazono, K; Sugitani, H	1
Briot, K	1
Bechtold, S; Borte, G; Borte, M; Dressler, F; Girschick, H; Roth, J	1
Gallucci, B; Schwartz, AL; Winters-Stone, K	1
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T	1
Dijkgraaf, MG; Gerlag, DM; Klaasen, R; Tak, PP; van Eck-Smit, BL; Wijbrandts, CA	1
Ansell, G; Evans, S; Jackson, CT; Lewis-Jones, S	1
Leonidas, JC; Schwartz, AM	1
Gella Lobo, E; González Ripoll, M; Moratinos Palomero, P; Serrano Galnares, J; Wilhelmi Ayza, M	1
Bakker, WK; Bos, JD; Dijkstra, PF; Dinant, HJ; van Soesbergen, RM; Zonneveld, IM	1
Buckley, LM; Cartularo, KS; Cooper, SM; Leib, ES; Vacek, PM	1
Rooney, P	1
Mizushima, Y; Suzuki, Y	1
Náfrádi, L; Toldy, E; Varga, L	1
Dequeker, J; Westhovens, R	1
Capell, H; Hamilton, J	1
Cranney, AB; Kanigsberg, ND; Kraag, GR; McKendry, RJ; Ooi, DS; Smith, CD; Wells, GA	1
Ide, M; Itoh, G; Suzuki, Y; Uehara, R	1
Kita, K; Sierakowski, S	1
Freeman-Narrod, M; Narrod, SA	1
Babcock, AL; Stanisavljevic, S	1
Heyn, R; Krivit, W; Nesbit, M; Sharp, H	1
Fill, H; Haas, H; Koller, A; Kurz, R; Riccabona, G	1
Wells, AU	1
McLain, DA	1
Bruning, PF; de Jong-Bakker, M; Hart, A; Pit, MJ; van den Ende, A; van Enk, A	1
Grisanti, JM; Mazanec, DJ	1
Melhorn, DK; Newman, AJ	1
Melhorn, DK; Newman, AJ; O'Regan, S	1
Frech, RS; Ragab, AH; Vietti, TJ	1

Reviews

15 review(s) available for methotrexate and Osteoporosis

Article	Year
Clinical features of methotrexate osteopathy in rheumatic musculoskeletal disease: A systematic review. Seminars in arthritis and rheumatism, 2022, Volume: 52 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Female; Humans; Methotrexate; Osteoporosis	2022
Methotrexate osteopathy: five cases and systematic literature review. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021, Volume: 32, Issue:2 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone Diseases; Child; Humans; Methotrexate; Osteoporosis	2021
[Glucocorticoids in the treatment of giant cell arteritis : How much, how long and how to spare?] Zeitschrift fur Rheumatologie, 2021, Volume: 80, Issue:4 Topics: Giant Cell Arteritis; Glucocorticoids; Humans; Methotrexate; Osteoporosis; Recurrence	2021
Epidemiology of rheumatoid arthritis, clinical aspects and socio-economic determinants in Pakistani patients: A systematic review and meta-analysis. JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:3 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Cardiovascular Diseases; Comorbidity; Cost of Illness; Depression; Depressive Disorder; Fibromyalgia; Methotrexate; Osteoporosis; Pakistan; Prevalence; Risk Factors; Social Class	2019
Osteoporosis and Psoriasis. Actas dermo-sifiliograficas, 2019, Volume: 110, Issue:8 Topics: Adrenal Cortex Hormones; Bone and Bones; Bone Density; Densitometry; Female; Fractures, Spontaneous; Humans; Immunosuppressive Agents; Male; Methotrexate; Osteoporosis; Psoriasis; Risk Factors; Vitamin D	2019
[Secondary osteoporosis UPDATE. Rheumatoid arthritis and bone damage: trends in treatment]. Clinical calcium, 2010, Volume: 20, Issue:5 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Bone Density Conservation Agents; Bone Remodeling; Denosumab; Diphosphonates; Glucocorticoids; Humans; Methotrexate; Osteoclasts; Osteoporosis; RANK Ligand; Synovial Membrane; Tumor Necrosis Factor-alpha	2010
Osteoporosis drug therapy strategies in the setting of disease-modifying agents for autoimmune disease. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:2 Topics: Autoimmune Diseases; Bone Density; Bone Density Conservation Agents; Humans; Immunosuppressive Agents; Methotrexate; Osteoporosis; Tumor Necrosis Factor-alpha	2013
[Treatment of Crohn's disease]. Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:3 Topics: Acute Disease; Adjuvants, Immunologic; Adrenal Cortex Hormones; Algorithms; Aminosalicylic Acids; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Case-Control Studies; Clinical Trials as Topic; Crohn Disease; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Methotrexate; Metronidazole; Osteoporosis; Prednisolone; Prednisone; Randomized Controlled Trials as Topic; Time Factors	2003
[Non-corticosteroid drug-induced metabolic bone disease]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:10 Pt 2 Topics: Aged; Animals; Anticoagulants; Anticonvulsants; Antipsychotic Agents; Aromatase Inhibitors; Bone Density; Child; Cyclosporins; Densitometry; Disease Progression; Diuretics; Female; Follow-Up Studies; Fractures, Bone; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Iatrogenic Disease; Immunosuppressive Agents; Lithium Compounds; Male; Menopause; Methotrexate; Middle Aged; Osteomalacia; Osteoporosis; Osteoporosis, Postmenopausal; Placebos; Prospective Studies; Protease Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tacrolimus; Thyroid Hormones; Time Factors	2006
[Pathologic condition of osteoporosis in rheumatoid arthritis]. Clinical calcium, 2007, Volume: 17, Issue:8 Topics: Arthritis, Rheumatoid; Bone Remodeling; Bone Resorption; Cell Differentiation; Cyclosporine; Disease Progression; Glucocorticoids; Humans; Menopause; Methotrexate; Osteoclasts; Osteoporosis; RANK Ligand; Tumor Necrosis Factor-alpha	2007
Osteoporosis in rheumatoid arthritis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1997, Volume: 7 Suppl 3 Topics: Adrenal Cortex Hormones; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Folic Acid Antagonists; Humans; Menopause; Methotrexate; Middle Aged; Movement; Osteoporosis; Rats; Sex Factors	1997
Rheumatoid arthritis and osteoporosis. Zeitschrift fur Rheumatologie, 2000, Volume: 59 Suppl 1 Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fractures, Spontaneous; Humans; Male; Methotrexate; Osteoporosis; Risk Factors	2000
The treatment of juvenile arthritis. Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7 Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Etanercept; Folic Acid Antagonists; Glucocorticoids; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunologic Factors; Infliximab; Methotrexate; Osteoporosis; Receptors, Tumor Necrosis Factor; Uveitis	2001
[Bone destruction and bone loss in rheumatoid arthritis--mechanism, prevention and treatment]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 3 Topics: Arthritis, Rheumatoid; Bone Density; Bone Resorption; Calcium, Dietary; Cholecalciferol; Cytokines; Glycoproteins; Humans; Methotrexate; Osteoclasts; Osteoporosis; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Synovial Membrane	2002
Drug-induced osteoporosis. Cleveland Clinic journal of medicine, 1989, Volume: 56, Issue:3 Topics: Adrenal Cortex Hormones; Adult; Child; Female; Heparin; Humans; Methotrexate; Osteoporosis; Pregnancy	1989

Trials

8 trial(s) available for methotrexate and Osteoporosis

Article	Year
Bone loss in patients with active early rheumatoid arthritis: infliximab and methotrexate compared with methotrexate treatment alone. Explorative analysis from a 12-month randomised, double-blind, placebo-controlled study. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:12 Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infliximab; Male; Methotrexate; Middle Aged; Osteoporosis	2009
Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:4 Topics: Absorptiometry, Photon; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone Density Conservation Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Hip Joint; Humans; Lumbar Vertebrae; Male; Methotrexate; Middle Aged; Osteoporosis; Prednisone; Severity of Illness Index; Tumor Necrosis Factor-alpha	2013
Exercise effects on bone mineral density in women with breast cancer receiving adjuvant chemotherapy. Oncology nursing forum, 2007, Volume: 34, Issue:3 Topics: Antineoplastic Agents; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Exercise Therapy; Female; Glucocorticoids; Humans; Menopause; Methotrexate; Middle Aged; Osteoporosis; Prospective Studies	2007
Bone mineral density in rheumatoid arthritis patients 1 year after adalimumab therapy: arrest of bone loss. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:3 Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; C-Reactive Protein; Drug Therapy, Combination; Female; Femur Neck; Glucocorticoids; Humans; Lumbar Vertebrae; Male; Methotrexate; Middle Aged; Osteoporosis; Prednisone; Prospective Studies; Severity of Illness Index; Time Factors; Tumor Necrosis Factor-alpha	2009
Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. The Journal of rheumatology, 1997, Volume: 24, Issue:8 Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Calcium; Cholecalciferol; Drug Therapy, Combination; Female; Femur Neck; Humans; Lumbar Vertebrae; Male; Methotrexate; Middle Aged; Osteoporosis; Prednisone; Prospective Studies	1997
[Measure of bone loss in rheumatoid arthritis]. Orvosi hetilap, 1999, Feb-07, Volume: 140, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Densitometry; Female; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal	1999
The effect of low dose methotrexate on bone density. The Journal of rheumatology, 2001, Volume: 28, Issue:11 Topics: Absorptiometry, Photon; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Middle Aged; Osteoporosis; Prospective Studies; Severity of Illness Index	2001
Acute lymphocytic leukemia in children: maintenance therapy with methotrexat administered intermittently. Acute Leukemia Group B. JAMA, 1969, Feb-03, Volume: 207, Issue:5 Topics: Adolescent; Adult; Blood Platelets; Bone Marrow Cells; Bone Marrow Examination; Child; Child, Preschool; Dyspnea; Female; Gastrointestinal Diseases; Hemoglobins; Herpesviridae Infections; Humans; Infant; Infant, Newborn; Infections; Injections, Intramuscular; Leukemia, Lymphoid; Leukocyte Count; Leukopenia; Male; Methotrexate; Mouth Diseases; Neurologic Manifestations; Osteoporosis; Pneumonia; Pneumonia, Pneumocystis; Prednisolone; Respiratory Tract Diseases; Thrombocytopenia; Vincristine	1969

Other Studies

43 other study(ies) available for methotrexate and Osteoporosis

Article	Year
Osteonecrosis of the Jaw in Two Rheumatoid Arthritis Patients Not Treated with a Bisphosphonate. Acta medica Okayama, 2023, Volume: 77, Issue:1 Topics: Arthritis, Rheumatoid; Diphosphonates; Humans; Methotrexate; Osteonecrosis; Osteoporosis	2023
[Does MTX-induced osteoporosis exist?] Zeitschrift fur Rheumatologie, 2020, Volume: 79, Issue:9 Topics: Humans; Immunosuppressive Agents; Methotrexate; Osteoporosis	2020
Correspondence on 'Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and Mendelian randomisation study'. Annals of the rheumatic diseases, 2023, Volume: 82, Issue:1 Topics: Arthritis, Psoriatic; Humans; Methotrexate; Osteoporosis; Psoriasis	2023
Vitamin D and Calcium Are Required during Denosumab Treatment in Osteoporosis with Rheumatoid Arthritis. Nutrients, 2017, Apr-26, Volume: 9, Issue:5 Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Calcium Carbonate; Denosumab; Dietary Supplements; Female; Humans; Methotrexate; Osteoporosis; Prednisolone; Retrospective Studies; Vitamin D	2017
Factors influencing spinal sagittal balance, bone mineral density, and Oswestry Disability Index outcome measures in patients with rheumatoid arthritis. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018, Volume: 27, Issue:2 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Cross-Sectional Studies; Disability Evaluation; Female; Glucocorticoids; Humans; Lordosis; Low Back Pain; Male; Methotrexate; Middle Aged; Osteoporosis; Outcome Assessment, Health Care; Pelvis; Posture; Quality of Life; Radiography; Risk Factors; Spinal Curvatures; Surveys and Questionnaires	2018
[Diagnosing and treating rheumatoid arthritis]. Ugeskrift for laeger, 2018, Oct-29, Volume: 180, Issue:44 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Glucocorticoids; Humans; Methotrexate; Osteoporosis	2018
Permanent Discontinuation of Glucocorticoids in Polymyalgia Rheumatica Is Uncommon but May Be Enhanced by Amino Bisphosphonates. The Journal of rheumatology, 2019, Volume: 46, Issue:3 Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Bone Density Conservation Agents; Diphosphonates; Electronic Health Records; Female; Follow-Up Studies; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Osteoporosis; Polymyalgia Rheumatica; Prednisone; Retrospective Studies; Treatment Outcome	2019
The importance of inhibition of a catabolic pathway of methotrexate metabolism in its efficacy for rheumatoid arthritis. Medical hypotheses, 2019, Volume: 122 Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Drug Therapy, Combination; Female; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Male; Methotrexate; Osteoporosis; Purines; Raloxifene Hydrochloride; Rats; Rats, Inbred Lew; Treatment Outcome	2019
Are glucocorticoids harmful to bone in early rheumatoid arthritis? Annals of the New York Academy of Sciences, 2014, Volume: 1318 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Glucocorticoids; Humans; Methotrexate; Osteoporosis; Prednisone	2014
Bisphosphonate-associated osteonecrosis of jaw reoccurrence after methotrexate therapy: a case report. Journal of endodontics, 2014, Volume: 40, Issue:9 Topics: Aged; Alendronate; Amoxicillin; Anti-Bacterial Agents; Apicoectomy; Arthritis, Rheumatoid; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Drug Interactions; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Methotrexate; Osteoporosis; Tooth Extraction; Wound Healing	2014
Association of osteoprotegerin and bone loss after adjuvant chemotherapy in early-stage breast cancer. Molecular and cellular endocrinology, 2015, Feb-15, Volume: 402 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Osteoporosis; Osteoprotegerin; Primary Ovarian Insufficiency	2015
Effects of dexamethasone, celecoxib, and methotrexate on the histology and metabolism of bone tissue in healthy Sprague Dawley rats. Clinical interventions in aging, 2015, Volume: 10 Topics: Animals; Antirheumatic Agents; Biomarkers; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Celecoxib; Dexamethasone; Female; Femur; Lumbar Vertebrae; Methotrexate; Osteoporosis; Rats; Rats, Sprague-Dawley; X-Ray Microtomography	2015
Effects of TNF Inhibitors on Parathyroid Hormone and Wnt Signaling Antagonists in Rheumatoid Arthritis. Calcified tissue international, 2016, Volume: 99, Issue:4 Topics: Adalimumab; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone Remodeling; Bone Resorption; Certolizumab Pegol; Collagen Type I; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Osteoporosis; Parathyroid Hormone; Peptides; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Wnt Proteins; Wnt Signaling Pathway	2016
[Three patients with a fracture during methotrexate use, possibly due to methotrexate osteopathy]. Nederlands tijdschrift voor geneeskunde, 2008, Oct-25, Volume: 152, Issue:43 Topics: Aged; Bone Diseases, Metabolic; Female; Fractures, Stress; Humans; Immunosuppressive Agents; Inflammation; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteoporosis; Remission, Spontaneous	2008
[Paradigm shift in the therapy for rheumatoid arthritis and osteoporosis]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2008, Oct-10, Volume: 97, Issue:10 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Infliximab; Methotrexate; Osteoporosis; Practice Guidelines as Topic; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha	2008
An osteoporotic hip fracture in a 14-year-old girl undergoing chemotherapy and operated for knee osteosarcoma. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2009, Volume: 10, Issue:3 Topics: Adolescent; Antineoplastic Agents; Arthroplasty, Replacement, Knee; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Femur; Fracture Fixation, Internal; Hip Fractures; Humans; Ifosfamide; Immobilization; Magnetic Resonance Imaging; Methotrexate; Osteoporosis; Osteosarcoma; Postoperative Care; Radiography	2009
Rheumatoid arthritis in patient with homozygous haemoglobin C disease. Rheumatology international, 2011, Volume: 31, Issue:6 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Glucocorticoids; Hemoglobin C Disease; Homozygote; Humans; Methotrexate; Middle Aged; Osteoporosis; Prednisone; Remission Induction	2011
Prospective bone ultrasound patterns during childhood acute lymphoblastic leukemia treatment. Bone, 2010, Volume: 46, Issue:4 Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Density; Chi-Square Distribution; Child; Child, Preschool; Cyclophosphamide; Cytosine; Female; Fractures, Bone; Humans; Male; Mercaptopurine; Methotrexate; Osteonecrosis; Osteoporosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Time Factors; Ultrasonography; Vincristine	2010
Osteoporosis in children and young adults: a late effect after chemotherapy for bone sarcoma. Clinical orthopaedics and related research, 2012, Volume: 470, Issue:10 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Density; Bone Neoplasms; Child; Female; Humans; Male; Methotrexate; Osteoporosis; Osteosarcoma; Retrospective Studies; Time Factors; Young Adult	2012
Quantitative assessment of the clavicle radiostructure as a tool for estimation of the osteopathic effect of breast cancer chemotherapy. Breast cancer research and treatment, 2002, Volume: 73, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Breast Neoplasms; Clavicle; Cyclophosphamide; Female; Fluorouracil; Humans; Image Processing, Computer-Assisted; Methotrexate; Middle Aged; Osteoporosis; Premenopause; Radiography; Reproducibility of Results; Sensitivity and Specificity; Software	2002
Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis. Annals of the rheumatic diseases, 2003, Volume: 62, Issue:6 Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Female; Fractures, Spontaneous; Humans; Methotrexate; Osteoporosis; Radionuclide Imaging	2003
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. Advances in experimental medicine and biology, 2003, Volume: 527 Topics: Arthritis, Rheumatoid; Case-Control Studies; Etidronic Acid; Female; Humans; Kynurenine; Methotrexate; Neopterin; Osteoporosis; Prednisolone; Raloxifene Hydrochloride; Receptors, Glutamate; Tryptophan	2003
Effect of low dose methotrexate on bone density in women with rheumatoid arthritis: results from a multicenter cross-sectional study. The Journal of rheumatology, 2004, Volume: 31, Issue:7 Topics: Absorptiometry, Photon; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Cross-Sectional Studies; Female; Humans; Methotrexate; Middle Aged; Osteoporosis; Sex Factors	2004
[So that the patients.would be able to move for a long time after first diagnosis of rheumatism. Approach as an emergency!]. MMW Fortschritte der Medizin, 2004, Sep-09, Volume: 146, Issue:37 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Methotrexate; Osteoporosis; Receptors, Tumor Necrosis Factor; Time Factors; Tumor Necrosis Factor-alpha	2004
Risk factors for vertebral fracture in menopausal or postmenopausal Japanese women with rheumatoid arthritis: a cross-sectional and longitudinal study. Journal of bone and mineral metabolism, 2006, Volume: 24, Issue:2 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Humans; Incidence; Japan; Longitudinal Studies; Lumbar Vertebrae; Menopause; Methotrexate; Middle Aged; Osteoclasts; Osteoporosis; Postmenopause; Risk Factors; Sensitivity and Specificity; Spinal Fractures; Spine; Steroids; Time Factors	2006
[Diagnosis, prophylaxis and therapy of osteoporosis in juvenile idiopathic arthritis: consensus statement of the German Association for Pediatric Rheumatology]. Zeitschrift fur Rheumatologie, 2007, Volume: 66, Issue:5 Topics: Absorptiometry, Photon; Adolescent; Arthritis, Juvenile; Calcium; Child; Diphosphonates; Exercise Therapy; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Muscle Strength; Muscular Atrophy; Osteoporosis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin D	2007
Cytotoxic drugs for non-neoplastic disease. British medical journal (Clinical research ed.), 1983, Sep-10, Volume: 287, Issue:6394 Topics: Fractures, Spontaneous; Humans; Male; Methotrexate; Middle Aged; Osteoporosis; Psoriasis	1983
Methotrexate osteopathy. Skeletal radiology, 1984, Volume: 11, Issue:1 Topics: Bone and Bones; Bone Diseases; Burkitt Lymphoma; Child, Preschool; Fractures, Bone; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Ossification, Heterotopic; Osteoporosis; Radiography	1984
[Letterer-Siwe in an eighteen-month child (author's transl)]. Anales espanoles de pediatria, 1981, Volume: 14, Issue:6 Topics: Adrenal Cortex Hormones; Biopsy; Bone Resorption; Histiocytosis, Langerhans-Cell; Humans; Infant; Male; Methotrexate; Osteolysis; Osteoporosis; Prognosis; Sella Turcica; Skin; Skin Diseases; Sphenoid Bone	1981
Methotrexate osteopathy in long-term, low-dose methotrexate treatment for psoriasis and rheumatoid arthritis. Archives of dermatology, 1996, Volume: 132, Issue:2 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Female; Fractures, Stress; Humans; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteoporosis; Psoriasis; Radiography	1996
Methotrexate osteopathy. The Journal of rheumatology, 1997, Volume: 24, Issue:10 Topics: Arthritis, Rheumatoid; Fractures, Bone; Humans; Methotrexate; Osteoporosis; Risk Factors	1997
Drugs for rheumatoid arthritis. The Medical letter on drugs and therapeutics, 2000, Jul-10, Volume: 42, Issue:1082 Topics: Administration, Oral; Adrenal Cortex Hormones; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Central Nervous System Diseases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Methotrexate; Nausea; Osteoporosis; Plasmapheresis; Prednisone; Sulfasalazine; Tumor Necrosis Factor-alpha	2000
[The effect of low dose methotrexate treatment on bone mineral density in patients with rheumatoid arthritis]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 12, Issue:68 Topics: Absorptiometry, Photon; Adult; Arthritis, Rheumatoid; Bone Density; Female; Humans; Methotrexate; Osteoporosis; Sulfasalazine	2002
Chronic toxicity of methotrexate in mice. Journal of the National Cancer Institute, 1977, Volume: 58, Issue:3 Topics: Age Factors; Animals; Bone and Bones; Bone Marrow; Digestive System; Drug Administration Schedule; Female; Infertility, Male; Male; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Osteoporosis; Pregnancy; Skin; Species Specificity; Spleen; Testis	1977
Fractures in children treated with methotrexate for leukemia. Clinical orthopaedics and related research, 1977, Issue:125 Topics: Child; Female; Fracture Fixation; Fractures, Bone; Humans; Leukemia; Methotrexate; Osteoporosis	1977
Acute and chronic effects of methotrexate on hepatic, pulmonary, and skeletal systems. Cancer, 1976, Volume: 37, Issue:2 Suppl Topics: Bone and Bones; Humans; Leukemia, Lymphoid; Liver; Lung; Methotrexate; Osteoporosis; Pneumonia; Pulmonary Fibrosis; Scoliosis	1976
Osteopathy due to methotrexate. Osterreichische Zeitschrift fur Onkologie. Austrian journal of oncology, 1976, Sep-13, Volume: 3, Issue:3 Topics: Calcium; Child; Femoral Fractures; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteoporosis; Phosphates	1976
Corticosteroid induced osteoporosis in severe menstrual asthma. Steroid sparing drugs may be useful. BMJ (Clinical research ed.), 1992, Aug-15, Volume: 305, Issue:6850 Topics: Adult; Asthma; Female; Humans; Menstruation Disturbances; Methotrexate; Osteoporosis; Prednisolone	1992
Highlights of the Eighth Annual Rheumatology on the Beach. Alabama medicine : journal of the Medical Association of the State of Alabama, 1991, Volume: 60, Issue:11 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Methotrexate; Osteoporosis; Rheumatology; United States	1991
Bone mineral density after adjuvant chemotherapy for premenopausal breast cancer. British journal of cancer, 1990, Volume: 61, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Osteoporosis; Risk Factors	1990
Vertebral compression in childhood leukemia. American journal of diseases of children (1960), 1973, Volume: 125, Issue:6 Topics: Age Factors; Child; Female; Fractures, Spontaneous; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Osteoporosis; Prednisone; Radiography; Remission, Spontaneous; Spinal Diseases; Thoracic Vertebrae	1973
Methotrexate-induced bone pain in childhood leukemia. American journal of diseases of children (1960), 1973, Volume: 126, Issue:4 Topics: Bone Diseases; Bone Regeneration; Child; Child, Preschool; Female; Fractures, Bone; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteoporosis; Pain; Radiography; Remission, Spontaneous; Time Factors	1973
Osteoporotic fractures secondary to methotrexate therapy of acute leukemia in remission. Cancer, 1970, Volume: 25, Issue:3 Topics: Calcinosis; Child; Child, Preschool; Female; Fractures, Spontaneous; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteoporosis	1970