emodin has been researched along with Osteoporosis in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To identify micro-computed tomography (CT) imaging biomarkers for evaluating the effects of emodin, a potential drug to treat osteoporosis, in the mouse model of lipopolysaccharide (LPS)-mediated osteoporosis." | 7.80 | CT imaging biomarker for evaluation of emodin as a potential drug on LPS-mediated osteoporosis mice. ( Juhng, SK; Jung, ST; Kang, DM; Kim, JY; Lee, M; Lee, YH; Oh, JM; Yoon, KH, 2014) |
| "Emodin was administered orally (30 mg/kg body weight) every other day starting in the third week for 9 weeks." | 5.56 | Effects of emodin on inflammatory bowel disease-related osteoporosis. ( Luo, JS; Yang, Y; Zhao, X, 2020) |
| "To identify micro-computed tomography (CT) imaging biomarkers for evaluating the effects of emodin, a potential drug to treat osteoporosis, in the mouse model of lipopolysaccharide (LPS)-mediated osteoporosis." | 3.80 | CT imaging biomarker for evaluation of emodin as a potential drug on LPS-mediated osteoporosis mice. ( Juhng, SK; Jung, ST; Kang, DM; Kim, JY; Lee, M; Lee, YH; Oh, JM; Yoon, KH, 2014) |
| "Emodin was administered orally (30 mg/kg body weight) every other day starting in the third week for 9 weeks." | 1.56 | Effects of emodin on inflammatory bowel disease-related osteoporosis. ( Luo, JS; Yang, Y; Zhao, X, 2020) |
| "Osteoporosis is a bone pathology leading to increased fracture risk and challenging the quality of life." | 1.43 | NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells. ( Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Pengjam, Y; Yamaguchi, Y, 2016) |
| "Emodin is a natural anthraquinone derivative extracted from Chinese herbs, which have been used to treat bone diseases for thousands of years." | 1.40 | Emodin enhances osteogenesis and inhibits adipogenesis. ( Hao, YQ; Lu, ZM; Yang, F; Yuan, PW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, JS | 1 |
| Zhao, X | 1 |
| Yang, Y | 1 |
| Chen, X | 1 |
| Ren, S | 1 |
| Zhu, G | 1 |
| Wang, Z | 1 |
| Wen, X | 1 |
| Yang, F | 1 |
| Yuan, PW | 1 |
| Hao, YQ | 1 |
| Lu, ZM | 1 |
| Kang, DM | 1 |
| Yoon, KH | 1 |
| Kim, JY | 1 |
| Oh, JM | 1 |
| Lee, M | 1 |
| Jung, ST | 1 |
| Juhng, SK | 1 |
| Lee, YH | 1 |
| Kang, SN | 1 |
| Lee, JS | 1 |
| Park, JH | 2 |
| Cho, JH | 1 |
| Cho, KK | 1 |
| Lee, OH | 1 |
| Kim, IS | 1 |
| Pengjam, Y | 1 |
| Madhyastha, H | 1 |
| Madhyastha, R | 1 |
| Yamaguchi, Y | 1 |
| Nakajima, Y | 1 |
| Maruyama, M | 1 |
6 other studies available for emodin and Osteoporosis
| Article | Year |
|---|---|
Effects of emodin on inflammatory bowel disease-related osteoporosis.
Topics: Animals; Biomarkers; Bone and Bones; Bone Density; Cell Differentiation; Colon; Disease Models, Anim | 2020 |
Emodin suppresses cadmium-induced osteoporosis by inhibiting osteoclast formation.
Topics: Animals; Cadmium; Emodin; Environmental Pollutants; Lumbar Vertebrae; Male; Osteoclasts; Osteoporosi | 2017 |
Emodin enhances osteogenesis and inhibits adipogenesis.
Topics: Adipogenesis; Adipose Tissue; Animals; Bone and Bones; Bone Density; Bone Marrow; CCAAT-Enhancer-Bin | 2014 |
CT imaging biomarker for evaluation of emodin as a potential drug on LPS-mediated osteoporosis mice.
Topics: Animals; Biomarkers; Bone Remodeling; Bone Resorption; Emodin; Femur; Lipopolysaccharides; Male; Mic | 2014 |
In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts.
Topics: Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Chlorogenic Acid; Chromatograp | 2014 |
NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.
Topics: Aloe; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Emodin; Humans; I- | 2016 |