avicularin has been researched along with Osteoporosis* in 1 studies
1 other study(ies) available for avicularin and Osteoporosis
Article | Year |
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Avicularin Alleviates Osteoporosis in Ovariectomized Mice by Inhibiting Osteoclastogenesis through NF-κB Pathway Inhibition.
Osteoporosis (OP) is mainly manifested by bone loss and bone degeneration. OP is considered a risk factor for pathological fractures, as well as impacts the health of middle-aged and elderly individuals. Drug therapy remains the main treatment scheme for OP; however, its efficacy is limited and has been associated with serious side effects. Therefore, it is important to develop new, effective, and safe treatment methods for OP. Avicularin (AL) is a flavonoid and quercetin derivative from various plants. Our study showed that AL disrupts osteoclast activation and resorptive function Topics: Animals; Bone Resorption; Cell Differentiation; Female; Flavonoids; Humans; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; RANK Ligand | 2023 |