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arginyl-glycyl-aspartic acid and Osteoporosis

arginyl-glycyl-aspartic acid has been researched along with Osteoporosis in 16 studies

*Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. [MeSH]

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (31.25)18.2507
2000's9 (56.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duggan, ME; Duong, LT; Hartman, GD; Hoffman, WF; Huff, JR; Ihle, NC; Leu, CT; Meissner, RS; Nagy, RM; Naylor-Olsen, A; Perkins, JJ; Rodan, GA; Rodan, SB; Wesolowski, GA; Whitman, DB1
Chuang, WJ; Fu, WM; Lin, TH; Lin, YM; Liou, HC; Tu, HJ; Yang, RS1
Liu, J; Peng, S; Zhang, X; Zhao, M1
Li, C; Liu, J; Peng, L; Peng, S; Zhang, X; Zhao, M1
Gamsjaeger, S; Klaushofer, K; Paschalis, EP; Rumpler, M; Spitzer, S; Thaler, R; Varga, F; Zwerina, J1
Suzuki, K1
Chen, KM; Dai, CL; Ding, XY; Qiu, MC; Zhang, ML; Zhang, X1
Chen, W; Diao, W; Ji, J; Liu, J; Tang, J1
Duggan, ME; Duong, LT; Fernandez-Metzler, C; Hartman, GD; Leu, CT; Meissner, RS; Prueksaritanont, T; Rodan, GA; Rodan, SB; Zartman, AE1
Chang, HW; Peng, S; Wang, C; Xiong, Y; Zhao, M1
Dresner-Pollak, R; Rosenblatt, M1
Bianco, P; Fedarko, NS; Friedenstein, A; Grzesik, W; Hefferan, TE; Mintz, KP; Robey, PG; Van der Pluijm, G; Vetter, UK; Young, MF1
Oursler, MJ; Spelsberg, TC1
Chorev, M; Dresner-Pollak, R; Eshel, Y; Rosenblatt, M1
Engleman, VW; Griggs, DW; Horton, MA; Nickols, GA; Ross, FP; Ruminski, PG; Settle, SL; Teitelbaum, SL1
Askew, BC; Brashear, KM; Breslin, MJ; Coleman, PJ; Duggan, ME; Fernandez-Metzler, C; Hartman, GD; Hoffman, WF; Hunt, CA; Hutchinson, JH; Leu, CT; Libby, LA; Lynch, JJ; Lynch, R; Ma, B; McVean, CA; Merkle, KM; Prueksaritanont, T; Rodan, GA; Rodan, SB; Stump, GL; Wallace, AA1

Reviews

5 review(s) available for arginyl-glycyl-aspartic acid and Osteoporosis

ArticleYear
[Osteopontin].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 2

    Topics: Amino Acid Motifs; Animals; Bone Resorption; Gene Deletion; Humans; Hyaluronan Receptors; Oligopeptides; Osteoblasts; Osteoclasts; Osteogenesis; Osteopontin; Osteoporosis; Sialoglycoproteins

2004
Blockade of osteoclast-mediated bone resorption through occupancy of the integrin receptor: a potential approach to the therapy of osteoporosis.
    Journal of cellular biochemistry, 1994, Volume: 56, Issue:3

    Topics: Amino Acid Sequence; Animals; Bone Resorption; Cell Adhesion; Humans; Integrins; Ligands; Molecular Sequence Data; Oligopeptides; Osteoclasts; Osteoporosis

1994
Structure and molecular regulation of bone matrix proteins.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8 Suppl 2

    Topics: Bone Matrix; Collagen; Extracellular Matrix Proteins; Gene Expression Regulation; Glycoproteins; Humans; Oligopeptides; Osteoporosis; Phosphorylation; Protein Biosynthesis; Proteoglycans; Stereoisomerism

1993
Echistatin, a potential new drug for osteoporosis.
    Endocrinology, 1993, Volume: 132, Issue:3

    Topics: Animals; Bone Resorption; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Oligopeptides; Osteoporosis; Peptides; Platelet Aggregation Inhibitors; Viper Venoms

1993
Approach to discovering novel therapeutic agents for osteoporosis based on integrin receptor blockade.
    Biopolymers, 1995, Volume: 37, Issue:6

    Topics: Amino Acid Sequence; Bone Resorption; Chemistry, Pharmaceutical; Female; Humans; Integrins; Molecular Sequence Data; Oligopeptides; Osteoporosis; Peptides

1995

Other Studies

11 other study(ies) available for arginyl-glycyl-aspartic acid and Osteoporosis

ArticleYear
Nonpeptide alpha(v)beta(3) antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide.
    Bioorganic & medicinal chemistry letters, 2002, Jan-07, Volume: 12, Issue:1

    Topics: Amides; Binding, Competitive; Drug Design; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Molecular Conformation; Molecular Mimicry; Oligopeptides; Osteoporosis; Platelet Aggregation; Receptors, Vitronectin; Structure-Activity Relationship

2002
Inhibition of osteoporosis by the αvβ3 integrin antagonist of rhodostomin variants.
    European journal of pharmacology, 2017, Jun-05, Volume: 804

    Topics: Animals; Disintegrins; Female; Humans; Integrin alphaVbeta3; Male; Mice; Mutation; Oligopeptides; Osteoporosis; Peptides; Protein Domains; Rats; Serum Albumin

2017
Synthesis, evaluation and 3D QSAR analysis of novel estradiol-RGD octapeptide conjugates with oral anti-osteoporosis activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Administration, Oral; Alkaline Phosphatase; Animals; Blood Coagulation; Calcium; Endometrial Hyperplasia; Estradiol; Female; Femur; Mice; Mice, Inbred ICR; Minerals; Models, Molecular; Molecular Conformation; Oligopeptides; Organ Size; Osteoporosis; Phosphorus; Quantitative Structure-Activity Relationship; Reference Standards; Thromboembolism; Uterus

2009
3D QSAR of novel estrogen-RGD peptide conjugates: getting insight into structural dependence of anti-osteoporosis activity and side effect of estrogen in ERT.
    Bioorganic & medicinal chemistry, 2009, May-15, Volume: 17, Issue:10

    Topics: Amino Acid Sequence; Animals; Bone and Bones; Computer Simulation; Estrogen Replacement Therapy; Estrogens; Female; Humans; Mice; Models, Chemical; Oligopeptides; Osteoporosis; Peptides; Quantitative Structure-Activity Relationship

2009
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:2

    Topics: 3T3 Cells; Animals; Base Sequence; beta Catenin; Cell Line; Chemokine CCL5; Collagen Type I; Extracellular Matrix; fas Receptor; Focal Adhesion Kinase 1; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinase 13; Mice; Models, Biological; Oligopeptides; Osteoblasts; Osteoporosis; Paxillin; Protein Denaturation; RNA, Messenger; RNA, Small Interfering; Serum Amyloid A Protein; Signal Transduction

2013
[Distribution of tetracycline-arginine-glycine-aspartate-tyrosine in mice and its effect on bone].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004, Volume: 26, Issue:4

    Topics: Animals; Bone Density; Bone Remodeling; Female; Mice; Oligopeptides; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Tetracycline; Tissue Distribution; Tyrosine

2004
Bone loss induced by ovariectomy in rats is prevented by gene transfer of parathyroid hormone or an Arg-Gly-Asp-containing peptide.
    Biotechnology letters, 2005, Volume: 27, Issue:1

    Topics: Animals; Bone Density; Female; Oligopeptides; Organ Size; Osteoporosis; Ovariectomy; Parathyroid Hormone; Rats; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Uterus

2005
Nonpeptide alpha(v)beta3 antagonists: identification of potent, chain-shortened 7-oxo RGD mimetics.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: Animals; Dogs; Heterocyclic Compounds, 2-Ring; Integrin alphaVbeta3; Models, Chemical; Molecular Structure; Oligopeptides; Osteoporosis; Structure-Activity Relationship

2005
Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates.
    Journal of medicinal chemistry, 2007, Jul-12, Volume: 50, Issue:14

    Topics: Alkaline Phosphatase; Animals; Calcium; Endometrium; Estrogen Replacement Therapy; Estrogens; Female; Hyperplasia; Mice; Oligopeptides; Organ Size; Osteoporosis; Ovariectomy

2007
A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo.
    The Journal of clinical investigation, 1997, May-01, Volume: 99, Issue:9

    Topics: Amino Acids; Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Cell Adhesion; Cells, Cultured; Dentin; Female; Humans; Integrins; Oligopeptides; Osteoclasts; Osteoporosis; Ovariectomy; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Receptors, Vitronectin; Vitronectin

1997
Non-peptide alpha(v)beta(3) antagonists. Part 3: identification of potent RGD mimetics incorporating novel beta-amino acids as aspartic acid replacements.
    Bioorganic & medicinal chemistry letters, 2002, Jan-07, Volume: 12, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Dogs; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Molecular Mimicry; Oligopeptides; Osteoporosis; Protein Binding; Receptors, Vitronectin; Structure-Activity Relationship

2002