Page last updated: 2024-11-01

ofloxacin and Osteoporosis

ofloxacin has been researched along with Osteoporosis in 1 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

ExcerptRelevanceReference
"Levofloxacin is used in adult patients with cystic fibrosis but its pharmacokinetics is not well characterized in this population."9.12Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate. ( Allen, SE; Amsden, GW; Pai, MP, 2006)
"Levofloxacin is used in adult patients with cystic fibrosis but its pharmacokinetics is not well characterized in this population."5.12Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate. ( Allen, SE; Amsden, GW; Pai, MP, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pai, MP1
Allen, SE1
Amsden, GW1

Trials

1 trial available for ofloxacin and Osteoporosis

ArticleYear
Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2006, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Calcium Carbonate; Cations; Cross

2006