fasudil has been researched along with Osteoporosis in 2 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We hypothesis that Rho kinase inhibitor fasudil ameliorates osteoporosis following myocardial infarction (MI) by regulating cardiac calcitonin secretion." | 8.12 | Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion. ( Xiang, C; Xu, M; Zhang, D; Zhu, Y, 2022) |
| "We hypothesis that Rho kinase inhibitor fasudil ameliorates osteoporosis following myocardial infarction (MI) by regulating cardiac calcitonin secretion." | 4.12 | Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion. ( Xiang, C; Xu, M; Zhang, D; Zhu, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiang, C | 1 |
| Zhu, Y | 1 |
| Xu, M | 1 |
| Zhang, D | 1 |
| Ohnaka, K | 1 |
| Takayanagi, R | 1 |
1 review available for fasudil and Osteoporosis
| Article | Year |
|---|---|
[Rho-kinase inhibitor].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Drug Design; Humans; Intracellular Signaling | 2004 |
1 other study available for fasudil and Osteoporosis
| Article | Year |
|---|---|
Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion.
Topics: Animals; Calcitonin; Fibrosis; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Osteoporo | 2022 |