Assay ID | Title | Year | Journal | Article |
AID610935 | Antiinflammatory activity in ovalbumin-sensitized ip dosed BALB/c mouse asthma model assessed as reduction in IL-4 level in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID781156 | Antimigratory activity against human SGC7901 cells at 10 uM after 12 to 48 hrs by wound-healing assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID1544513 | Induction of neurite outgrowth in rat PC12 cells assessed as neurite bearing cells in absence of 20 ng/ml NGF incubated for 48 hrs by light microscopy | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID249073 | Concentration causing 50% inhibition of cancer cell growth against human lung H522 cell line | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID1204914 | Cytotoxicity against human Jurkat T cells assessed as appearance of viable cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID376608 | Neuroprotective effect against amyloid beta(25 to 35)-induced cell death in Harlan Sprague-Dawley rat pups cortical neurons assessed as cell viability at 10 uM treated 2 hrs before amyloid beta(25 to 35) treatment after 40 hrs by MTT assay | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 ISSN: 0163-3864 | Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. |
AID1408139 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of alpha-SMA mRNA level at 500 nM measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID1544507 | Cytotoxicity in mouse BV2 cells assessed as reduction in cell viability | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID611021 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in Ym-2 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID781151 | Cytotoxicity against human PC3 cells assessed as growth inhibition at 10 uM after 48 hrs by MTT assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID1761539 | Cytotoxicity against C57BL/6 mouse BMM cells assessed as reduction in cell viability measured after 48 hrs in presence of M-CSF by CCK8 assay | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213ISSN: 1768-3254 | Synthesis and evaluation of andrographolide derivatives as potent anti-osteoporosis agents in vitro and in vivo. |
AID1367187 | Growth inhibition of human KB cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID383495 | Antiproliferative activity against human HL60 cells by trypan blue assay | 2008 | Journal of natural products, May, Volume: 71, Issue:5 ISSN: 0163-3864 | ent-Labdane diterpenoid lactone stereoisomers from Andrographis paniculata. |
AID611032 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in goblet cell hyperplasia at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs using hematoxylin and eosin st | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1204904 | Binding affinity to 6His-tagged recombinant human NF-kappaB p50 N-terminal domain expressed in Escherichia coli BL21 (DE3) up to 50:1 compound to protein molar ratio after 2 hrs by mass spectrometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID1140535 | Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 ISSN: 1464-3405 | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
AID1367192 | Growth inhibition of human KKU-M213 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID380105 | Antimicrobial activity against Candida sake at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID380106 | Antimicrobial activity against Aspergillus niger at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID610929 | Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability at 3 to 120 uM after 24 to 48 hrs by MTS assay | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1204911 | Cytotoxicity against human Jurkat T cells assessed as appearance of early apoptotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID1140530 | Cytotoxicity against human HepG2.2.15 cells by MTT assay | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 ISSN: 1464-3405 | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
AID1544494 | Lipophilicity, log P of the compound | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID1544514 | Induction of neurite outgrowth in NGF-induced rat PC12 cells assessed as neurite bearing cells at 20 uM cotreated with 20 ng/ml NGF incubated for 48 hrs by methylene blue staining based light microscopy | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID611027 | Antiinflammatory activity in ip dosed BALB/c mouse asthma model assessed as reduction in ovalbumin-induced eosinophil counts in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by cell count | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610930 | Cytotoxicity against rat RBL2H3 cells assessed as reduction in cell viability at 3 to 120 uM after 24 to 48 hrs by MTS assay | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610932 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as reduction in NF-kappaB DNA binding activity at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by immunoblotting | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611022 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in YLK-40 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610934 | Inhibition of NF-kappaB p65 subunit in TNFalpha-stimulated human A549 cells assessed as reduction in DNA binding activity at 30 uM after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID380102 | Antimicrobial activity against Escherichia coli at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID1544506 | Induction of neurite outgrowth in NGF-induced rat PC12 cells assessed as neurite bearing cells cotreated with 20 ng/ml NGF incubated for 48 hrs by light microscopy | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID376606 | Neuroprotective effect against amyloid beta(25 to 35)-induced cell death in Harlan Sprague-Dawley rat pups cortical neurons assessed as cell viability at 1 uM treated 2 hrs before amyloid beta(25 to 35) treatment after 40 hrs by MTT assay | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 ISSN: 0163-3864 | Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. |
AID249075 | Concentration causing 50% inhibition of cancer cell growth against human colon SW620 cell line | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID611031 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in mucus production in lung at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs using PAS staining by histolo | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID380100 | Antimicrobial activity against Bacillus subtilis at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID1544501 | Neuroprotective activity against H2O2-induced toxicity in rat PC12 cells assessed as increase in cell viability at 20 uM pretreated for 24 hrs followed by H2O2 challenge and measured after 24 hrs by MTT assay | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID1367193 | Growth inhibition of human HuCCa1 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID610936 | Antiinflammatory activity in ovalbumin-sensitized ip dosed BALB/c mouse asthma model assessed as reduction in IL-5 level in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1367189 | Growth inhibition of human MCF7 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID611025 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in COX-2 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611118 | Toxicity in BALB/c mouse assessed as reduction in white blood cell count at 1 mg/kg, ip | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611026 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in Muc5ac mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610938 | Antiinflammatory activity in ovalbumin-sensitized ip dosed BALB/c mouse asthma model assessed as reduction in eotaxin level in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610941 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in IgG1 level in serum at 0.1 to 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID380103 | Antimicrobial activity against Micrococcus luteus at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID1204910 | Inhibition of TNF-alpha-stimulated NF-kappaB p50 (unknown origin) expressed in HEK293 cells at 1 to 100 uM preincubated for 4 hrs followed by TNF-alpha challenge measured after 24 hrs by secreted alkaline phosphatase reporter assay | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID1204913 | Cytotoxicity against human Jurkat T cells assessed as appearance of necrotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID376609 | Neuroprotective effect against amyloid beta(25 to 35)-induced cell death in Harlan Sprague-Dawley rat pups cortical neurons assessed as cell viability at 20 uM treated 2 hrs before amyloid beta(25 to 35) treatment after 40 hrs by MTT assay | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 ISSN: 0163-3864 | Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. |
AID376607 | Neuroprotective effect against amyloid beta(25 to 35)-induced cell death in Harlan Sprague-Dawley rat pups cortical neurons assessed as cell viability at 5 uM treated 2 hrs before amyloid beta(25 to 35) treatment after 40 hrs by MTT assay | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 ISSN: 0163-3864 | Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. |
AID1544504 | Induction of neurite outgrowth in NGF-induced rat PC12 cells assessed as neurite bearing cells at 20 uM cotreated with 20 ng/ml NGF incubated for 48 hrs by light microscopy | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID610943 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in VCAM-1 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610940 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in IgE level in serum at 0.1 to 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611024 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in IL-33 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611029 | Antiinflammatory activity in BALB/c mouse asthma model assessed as reduction in ovalbumin-induced macrophage counts in bronchoalveolar lavage fluid at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by cell | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID781155 | Cytotoxicity against human SGC7901 cells assessed as growth inhibition at 10 uM after 48 hrs by MTT assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID1367190 | Growth inhibition of human A549 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID1741322 | Aqueous stability of compound | 2020 | European journal of medicinal chemistry, Oct-15, Volume: 204ISSN: 1768-3254 | From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action. |
AID1408132 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID1367186 | Growth inhibition of mouse P388 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID781157 | Cytotoxicity against human 5637 cells assessed as growth inhibition at 10 uM after 48 hrs by MTT assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID611023 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in IL-17 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID781159 | Antimigratory activity against human 5637 cells at 10 uM after 12 to 48 hrs by wound-healing assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID264791 | Inhibition of alpha glucosidase at 100 uM | 2006 | Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10 ISSN: 0960-894X | Studies on the novel alpha-glucosidase inhibitory activity and structure-activity relationships for andrographolide analogues. |
AID1367195 | Growth inhibition of human HEK293 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID611020 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in Ym-1 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1408141 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of COL1A1 mRNA level at 500 nM measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID1544503 | Neuroprotective activity against 6-OHDA -induced toxicity in rat PC12 cells assessed as increase in cell viability at 20 uM pretreated for 24 hrs followed by 6-OHDA challenge and measured after 24 hrs by MTT assay | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID611107 | Cytotoxicity against human A549 cells assessed as reduction in cell viability at 3 to 120 uM after 24 to 48 hrs by MTS assay | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611104 | Inhibition of IgE-mediated rat RBL2H3 cell degranulation assessed as inhibition of beta-hexosaminidase release | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1140536 | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 ISSN: 1464-3405 | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
AID610937 | Antiinflammatory activity in ovalbumin-sensitized ip dosed BALB/c mouse asthma model assessed as reduction in IL-13 level in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1367188 | Growth inhibition of human HT-29 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID380104 | Antimicrobial activity against Candida albicans at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID1408138 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of TGFbeta1-induced increase in COL1A1 mRNA level at 500 nM preincubated for 1 hr followed by TGFbeta-1 addition measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID611119 | Toxicity in BALB/c mouse assessed as reduction in hematocrit at 1 mg/kg, ip | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID307364 | Inhibition of alpha-glucosidase at 100 uM | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 ISSN: 0968-0896 | Synthesis of andrographolide derivatives: a new family of alpha-glucosidase inhibitors. |
AID1140537 | Octanol-water partition coefficient, log P of the compound at 30 degC by HPLC analysis | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 ISSN: 1464-3405 | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
AID249081 | Concentration causing 50% inhibition of cancer cell growth against human ovarian SKOV3 cell line; nd = not done | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID1367191 | Growth inhibition of rat ASK cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID611103 | Inhibition of ovalbumin-induced mast cell degranulation in BALB/c mouse asthma model at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs using toluidine blue staining by cell counting | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611028 | Antiinflammatory activity in ip dosed BALB/c mouse asthma model assessed as reduction in ovalbumin-induced total cell counts in bronchoalveolar lavage fluid administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by cell count | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1408140 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of FN mRNA level at 500 nM measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID1408136 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of TGFbeta1-induced increase in alpha-SMA mRNA level at 500 nM preincubated for 1 hr followed by TGFbeta-1 addition measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID611106 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in methacholine-induced distensibility of the lung at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID249072 | Concentration causing 50% inhibition of cancer cell growth against human CNS U251 cell line | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID610933 | Inhibition of NF-kappaB p65 subunit translocation in TNFalpha-stimulated human A549 cells assessed as reduction in p65 level in nuclear extract at 30 uM after 24 hrs by immunoblotting | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID781152 | Antimigratory activity against human PC3 cells at 10 uM after 12 to 48 hrs by wound-healing assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 ISSN: 1464-3405 | Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide. |
AID610931 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as Inhibition of NF-kappaB p65 subunit nuclear translocation at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by i | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID264793 | Inhibition of beta glucosidase at 100 uM | 2006 | Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10 ISSN: 0960-894X | Studies on the novel alpha-glucosidase inhibitory activity and structure-activity relationships for andrographolide analogues. |
AID380101 | Antimicrobial activity against Staphylococcus aureus at 10 ug/ml by disk diffusion assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 ISSN: 0163-3864 | ent-Labdane diterpenoids from Andrographis paniculata. |
AID610939 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in total IgE level in serum at 0.1 to 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID249080 | Concentration causing 50% inhibition of cancer cell growth against human renal A498 cell line; nd = not done | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID1367194 | Growth inhibition of human KKU100 cells after 72 hrs by SRB assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23 ISSN: 1464-3405 | Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. |
AID611117 | Toxicity in BALB/c mouse assessed as reduction in red blood cell count at 1 mg/kg, ip | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610942 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in IgG2a level in serum at 0.1 to 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by ELISA | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID610944 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in E-selectin mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1408137 | Antifibrotic activity against mouse NIH/3T3 cells assessed as inhibition of TGFbeta1-induced increase in FN mRNA level at 500 nM preincubated for 1 hr followed by TGFbeta-1 addition measured after 24 hrs by qRT-PCR method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254 | Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives. |
AID249077 | Concentration causing 50% inhibition of cancer cell growth against human prostate DU145 cell line | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID611105 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model assessed as reduction in methacholine-induced maximum total lung resistance at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611018 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in MCP-1 mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1204912 | Cytotoxicity against human Jurkat T cells assessed as appearance of late apoptotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 ISSN: 1520-6025 | Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. |
AID249078 | Concentration causing 50% inhibition of cancer cell growth against human breast MCF-7/ADR cell line | 2004 | Bioorganic & medicinal chemistry letters, Sep-20, Volume: 14, Issue:18 ISSN: 0960-894X | Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. |
AID611019 | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse asthma model lung assessed as suppression in AMCase mRNA level at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by RT-PCR analysis | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID611030 | Antiinflammatory activity in BALB/c mouse asthma model assessed as reduction in ovalbumin-induced lymphocyte counts in bronchoalveolar lavage fluid at 1 mg/kg, ip administered 2 hrs before and 10 hrs after ovalbumin challenge measured after 24 hrs by cell | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1761538 | Anti-osteoporosis activity in C57BL/6 mouse BMM cells assessed as inhibition of M-CSF/RANKL-induced osteoclastogenesis by measuring reduction in multinucleated TRAP+ cells incubated for 5 days with media replenishment for every 48 hrs measured by TRAP-sta | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213ISSN: 1768-3254 | Synthesis and evaluation of andrographolide derivatives as potent anti-osteoporosis agents in vitro and in vivo. |
AID1741323 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL6 release at 5 to 10 uM preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by ELISA | 2020 | European journal of medicinal chemistry, Oct-15, Volume: 204ISSN: 1768-3254 | From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action. |
AID1741327 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha release at 5 to 10 uM preincubated for 1 hr followed by LPS stimulation and measured after 4 hrs by ELISA | 2020 | European journal of medicinal chemistry, Oct-15, Volume: 204ISSN: 1768-3254 | From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action. |
AID611120 | Toxicity in BALB/c mouse assessed as reduction in hemoglobin concentration at 1 mg/kg, ip | 2011 | Journal of natural products, Jun-24, Volume: 74, Issue:6 ISSN: 1520-6025 | Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation. |
AID1544493 | Antiinflammatory activity in mouse BV2 cells assessed as reduction in LPS-induced NO production at 20 uM incubated for 24 hrs by Griess method | 2019 | Bioorganic & medicinal chemistry, 06-01, Volume: 27, Issue:11 ISSN: 1464-3391 | Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 ISSN: 1945-7170 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | 2022 | The Journal of biological chemistry, 08, Volume: 298, Issue:8 ISSN: 1083-351X | |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 ISSN: 1945-7170 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 ISSN: 2472-5560 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 ISSN: 1521-0111 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 ISSN: 1091-6490 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 ISSN: 1091-6490 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 ISSN: 1521-0111 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1347087 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Confirmatory Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173ISSN: 1872-9096 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347088 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): Viability assay - Alamar blue signal for LCMV Confirmatory Screen | 2020 | Antiviral research, 01, Volume: 173ISSN: 1872-9096 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347084 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Confirmatory Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173ISSN: 1872-9096 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
AID1347081 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Confirmatory Screen | 2020 | Antiviral research, 01, Volume: 173ISSN: 1872-9096 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
alpha-hydroxyglutarate | | 2-hydroxydicarboxylic acid; dicarboxylic fatty acid | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-isopropylmalate | | 2-hydroxy carboxylic acid; 3-hydroxy carboxylic acid; dicarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acetoacetic acid | | 3-oxo fatty acid; ketone body | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-hydroxybenzyl alcohol | | hydroxybenzyl alcohol; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-carbamoyl-beta-alanine | | beta-alanine derivative | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethylene glycol | | ethanediol; glycol | metabolite; mouse metabolite; solvent; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acetoin | | methyl ketone; secondary alpha-hydroxy ketone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ammonium hydroxide | | azane; gas molecular entity; mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor; metabolite; mouse metabolite; neurotoxin; NMR chemical shift reference compound; nucleophilic reagent; refrigerant | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
benzyl alcohol | | benzyl alcohols | antioxidant; fragrance; metabolite; solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
carbon monoxide | | carbon oxide; gas molecular entity; one-carbon compound | biomarker; EC 1.9.3.1 (cytochrome c oxidase) inhibitor; human metabolite; ligand; metabolite; mitochondrial respiratory-chain inhibitor; mouse metabolite; neurotoxin; neurotransmitter; P450 inhibitor; probe; signalling molecule; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
formic acid | | monocarboxylic acid | antibacterial agent; astringent; metabolite; protic solvent; solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-hydroxymandelic acid | | 2-hydroxy carboxylic acid; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aminoethylphosphonic acid | | phosphonic acids; primary amino compound; zwitterion | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydrogen sulfide | | gas molecular entity; hydracid; mononuclear parent hydride; sulfur hydride | Escherichia coli metabolite; genotoxin; metabolite; signalling molecule; toxin; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-aminophenol | | aminophenol | allergen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n(1)-acetylspermidine | | acetylspermidine | Escherichia coli metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aminocaproic acid | | amino acid zwitterion; epsilon-amino acid; omega-amino fatty acid | antifibrinolytic drug; hematologic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydrouracil | | pyrimidone | Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydroxyacetone | | ketotriose; primary alpha-hydroxy ketone | antifungal agent; Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dimethylamine | | methylamines; secondary aliphatic amine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycolic acid | | 2-hydroxy monocarboxylic acid; primary alcohol | keratolytic drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydantoin-5-propionic acid | | imidazolidine-2,4-dione; monocarboxylic acid | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
niacinamide | | pyridine alkaloid; pyridinecarboxamide; vitamin B3 | anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
niacin | | pyridine alkaloid; pyridinemonocarboxylic acid; vitamin B3 | antidote; antilipemic drug; EC 3.5.1.19 (nicotinamidase) inhibitor; Escherichia coli metabolite; human urinary metabolite; metabolite; mouse metabolite; plant metabolite; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
orotic acid | | pyrimidinemonocarboxylic acid | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oxaloacetic acid | | C4-dicarboxylic acid; oxo dicarboxylic acid | geroprotector; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
porphobilinogen | | aralkylamino compound; dicarboxylic acid; pyrroles | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-propanol | | propan-1-ols; short-chain primary fatty alcohol | metabolite; protic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
trimethyloxamine | | tertiary amine oxide | Escherichia coli metabolite; metabolite; osmolyte | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-hydroxymelatonin | | acetamides; tryptamines | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetylphenylalanine | | N-acetyl-amino acid; phenylalanine derivative | antidepressant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetyltryptophan | | N-acetyl-amino acid; tryptophan derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arecoline | | enoate ester; methyl ester; pyridine alkaloid; tetrahydropyridine | metabolite; muscarinic agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aristolochic acid i | | aristolochic acids; aromatic ether; C-nitro compound; cyclic acetal; monocarboxylic acid; organic heterotetracyclic compound | carcinogenic agent; metabolite; mutagen; nephrotoxin; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
berberine | | alkaloid antibiotic; berberine alkaloid; botanical anti-fungal agent; organic heteropentacyclic compound | antilipemic drug; antineoplastic agent; antioxidant; EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor; EC 1.21.3.3 (reticuline oxidase) inhibitor; EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.11.10 (IkappaB kinase) inhibitor; EC 3.1.1.4 (phospholipase A2) inhibitor; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor; EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; geroprotector; hypoglycemic agent; metabolite; potassium channel blocker | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dibutyl phthalate | | diester; phthalate ester | EC 3.2.1.20 (alpha-glucosidase) inhibitor; environmental contaminant; metabolite; plasticiser; teratogenic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydroxymethyltolbutamide | | benzyl alcohols; sulfonamide; ureas | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl salicylate | | benzoate ester; methyl ester; salicylates | flavouring agent; insect attractant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
myristicin | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenmetrazine | | morpholines | metabolite; sympathomimetic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylbutazone | | pyrazolidines | antirheumatic drug; EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor; metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
safrole | | benzodioxoles | flavouring agent; insecticide; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,2'-thiodiethanol | | aliphatic sulfide; diol | antineoplastic agent; antioxidant; metabolite; solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sorbitol | | glucitol | cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alloxan | | pyrimidone | hyperglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thymidine | | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glutamine | | amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
allyl isothiocyanate | | alkenyl isothiocyanate; isothiocyanate | antimicrobial agent; antineoplastic agent; apoptosis inducer; lachrymator; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-methyltryptamine | | tryptamine alkaloid; tryptamines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-deoxypyridoxine | | hydroxymethylpyridine; methylpyridines; monohydroxypyridine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cycloserine | | 4-amino-1,2-oxazolidin-3-one; organonitrogen heterocyclic antibiotic; organooxygen heterocyclic antibiotic; zwitterion | antiinfective agent; antimetabolite; antitubercular agent; metabolite; NMDA receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
17-alpha-hydroxyprogesterone | | 17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; tertiary alpha-hydroxy ketone | human metabolite; metabolite; mouse metabolite; progestin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mannitol | | mannitol | allergen; antiglaucoma drug; compatible osmolytes; Escherichia coli metabolite; food anticaking agent; food bulking agent; food humectant; food stabiliser; food thickening agent; hapten; metabolite; osmotic diuretic; sweetening agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenacyl bromide | | acetophenones; alpha-bromoketone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
trichloroacetic acid | | monocarboxylic acid; organochlorine compound | carcinogenic agent; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acrylic acid | | alpha,beta-unsaturated monocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-methylacetamide | | acetamides; monocarboxylic acid amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bis(4-hydroxyphenyl)sulfone | | bisphenol; sulfone | endocrine disruptor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rotenone | | organic heteropentacyclic compound; rotenones | antineoplastic agent; metabolite; mitochondrial NADH:ubiquinone reductase inhibitor; phytogenic insecticide; piscicide; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-amino-4-hydroxy-2-naphthalenesulfonic acid | | aminonaphthalenesulfonic acid; naphthols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl benzoate | | benzoate ester; methyl ester | insect attractant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-dichlorobenzene | | dichlorobenzene | hepatotoxic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,4-diaminotoluene | | aminotoluene | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-butyrolactone | | butan-4-olide | metabolite; neurotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sulfosalicylic acid | | arenesulfonic acid; benzoic acids; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl lactate | | ethyl ester; lactate ester; secondary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
furaldehyde | | aldehyde; furans | Maillard reaction product; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thiophene-2-carboxaldehyde | | aldehyde; thiophenes | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-resorcylic acid | | dihydroxybenzoic acid; resorcinols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methylenebis(chloroaniline) | | chloroaniline | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-phenylethyl acetate | | acetate ester | metabolite; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dibenzyl ether | | benzyl ether | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl propionate | | propanoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
citronellal | | aldehyde; monoterpenoid | antifungal agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl oenanthate | | fatty acid ethyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl caprylate | | fatty acid ethyl ester; octanoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl laurate | | fatty acid ethyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acetic anhydride | | acyclic carboxylic anhydride | metabolite; reagent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl isovalerate | | fatty acid ethyl ester; olefinic compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-butyl n-butyrate | | butyrate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl decanoate | | decanoate ester; fatty acid ethyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl octanoate | | fatty acid methyl ester; octanoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-octanone | | methyl ketone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hexylamine | | primary aliphatic amine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lauric acid methyl ester | | dodecanoate ester; fatty acid methyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
octylamine | | primary aliphatic amine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-decyl alcohol | | decanol; primary alcohol | metabolite; pheromone; protic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl palmitate | | fatty acid methyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
maltol | | 4-pyranones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chloranil | | 1,4-benzoquinones; organochlorine compound | EC 2.7.1.33 (pantothenate kinase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dibenzoylmethane | | aromatic ketone; beta-diketone | antimutagen; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl anthranilate | | benzoate ester | flavouring agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
benzyl acetate | | acetate ester; benzyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl acetate | | acetate ester; ethyl ester; volatile organic compound | EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor; metabolite; polar aprotic solvent; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dibenzyl disulfide | | organic aromatic compound; organic disulfide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mequinol | | methoxybenzenes; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
gamma-resorcylic acid | | dihydroxybenzoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kynuramine | | kynurenamines; primary amino compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-methylpyrazole-3-carboxylic acid | | monocarboxylic acid; pyrazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-trifluoromethylaniline | | (trifluoromethyl)benzenes; substituted aniline | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methylguanidine | | guanidines | EC 1.14.13.39 (nitric oxide synthase) inhibitor; metabolite; uremic toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
liriodenine | | alkaloid antibiotic; cyclic ketone; organic heteropentacyclic compound; oxacycle; oxoaporphine alkaloid | antifungal agent; antimicrobial agent; antineoplastic agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
plumbagin | | hydroxy-1,4-naphthoquinone; phenols | anticoagulant; antineoplastic agent; immunological adjuvant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
imperatorin | | psoralens | EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
osthol | | botanical anti-fungal agent; coumarins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Dillapiole | | benzodioxoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
coumaran | | 1-benzofurans | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1,3-propanediol | | propane-1,3-diols | metabolite; protic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tridecanedioic acid | | alpha,omega-dicarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
physcione | | dihydroxyanthraquinone | anti-inflammatory agent; antibacterial agent; antifungal agent; antineoplastic agent; apoptosis inducer; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apiole | | benzodioxoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
flavone | | flavones | metabolite; nematicide | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cetyl palmitate | | hexadecanoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-amyl butyrate | | butyrate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-aminobutyric acid | | amino acid zwitterion; beta-amino acid; monocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl lactate | | lactate ester; methyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
paeonol | | methoxybenzenes; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,2-dimethylbutyric acid | | dimethylbutyric acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-chloroacrylic acid | | alpha,beta-unsaturated monocarboxylic acid; chlorocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
galactitol | | hexitol | Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-methyluracil | | nucleobase analogue; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-pyrrolidone | | pyrrolidin-2-ones | metabolite; polar solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-ethylacetamide | | acetamides | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-methyluracil | | pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylglutaric acid | | alpha,omega-dicarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
amyl acetate | | acetate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dibenzothiophene 5-oxide | | dibenzothiophenes | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-acetamidoethanethiol | | acetamides | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-hydroxyquinoxaline | | hydroxyquinoxaline | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,4-dihydroxyacetophenone | | acetophenones; catechols; dihydroxyacetophenone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl hippurate | | glycine derivative; methyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isobarbaloin | | anthracenes; C-glycosyl compound; cyclic ketone; phenols | laxative; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vincamine | | alkaloid ester; hemiaminal; methyl ester; organic heteropentacyclic compound; vinca alkaloid | antihypertensive agent; metabolite; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl tert-butyl ether | | ether | fuel additive; metabolite; non-polar solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-octylphenol | | phenols | metabolite; surfactant; xenoestrogen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dronabinol | | benzochromene; diterpenoid; phytocannabinoid; polyketide | cannabinoid receptor agonist; epitope; hallucinogen; metabolite; non-narcotic analgesic | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenethyl isothiocyanate | | isothiocyanate | antineoplastic agent; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-methoxy-1,4-naphthoquinone | | 1,4-naphthoquinones; enol ether | antimicrobial agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aviprin | | furanocoumarin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydroxyphenytoin | | imidazolidine-2,4-dione; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
squaric acid | | alicyclic ketone; carbon oxoacid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl methanethiosulfonate | | sulfonic acid derivative; thiosulfonate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arabinofuranosyluracil | | N-glycosyl compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-aminonicotinic acid | | aminonicotinic acid; aminopyridine; aromatic amine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mannose | | D-aldohexose; D-mannose; mannopyranose | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,3-hexanedione | | alpha-diketone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tabersonine | | alkaloid ester; methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,3-dimethylglutarate | | alpha,omega-dicarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
raspberry ketone | | methyl ketone; phenols | androgen antagonist; cosmetic; flavouring agent; fragrance; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
laurolitsine | | aporphine alkaloid; aromatic ether; phenols | HIV-1 integrase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
helenalin | | cyclic ketone; gamma-lactone; organic heterotricyclic compound; secondary alcohol; sesquiterpene lactone | anti-inflammatory agent; antineoplastic agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diethyl malate | | malate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
carbendazim | | benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester | antifungal agrochemical; antinematodal drug; metabolite; microtubule-destabilising agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glucoheptonate | | carbohydrate acid; monocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
deslanoside | | 12beta-hydroxy steroid; 14beta-hydroxy steroid; cardenolide glycoside; tetrasaccharide derivative | anti-arrhythmia drug; cardiotonic drug; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
streptozocin | | N-acylglucosamine; N-nitrosoureas | antimicrobial agent; antineoplastic agent; DNA synthesis inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pedalitin | | monomethoxyflavone; tetrahydroxyflavone | EC 1.17.3.2 (xanthine oxidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl nonanoate | | fatty acid ethyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl hexanoate | | fatty acid ethyl ester; hexanoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
butyl acetate | | acetate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1,4-dioxane | | dioxane; volatile organic compound | carcinogenic agent; metabolite; NMR chemical shift reference compound; non-polar solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoamyl acetate | | acetate ester | metabolite; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ribostamycin | | amino cyclitol glycoside; aminoglycoside antibiotic | antibacterial drug; antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tramadol | | 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol | adrenergic uptake inhibitor; antitussive; capsaicin receptor antagonist; delta-opioid receptor agonist; kappa-opioid receptor agonist; metabolite; mu-opioid receptor agonist; muscarinic antagonist; nicotinic antagonist; NMDA receptor antagonist; opioid analgesic; serotonergic antagonist; serotonin uptake inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-pentylpyrone | | 2-pyranones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
paclitaxel | | taxane diterpenoid; tetracyclic diterpenoid | antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-methylhistamine | | aralkylamino compound; imidazoles | histamine agonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
perfosfamide | | nitrogen mustard; organochlorine compound; peroxol; phosphorodiamide | alkylating agent; antineoplastic agent; drug allergen; immunosuppressive agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
castanospermine | | indolizidine alkaloid | anti-HIV-1 agent; anti-inflammatory agent; EC 3.2.1.* (glycosidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pravastatin | | 3-hydroxy carboxylic acid; carbobicyclic compound; carboxylic ester; hydroxy monocarboxylic acid; secondary alcohol; statin (semi-synthetic) | anticholesteremic drug; environmental contaminant; metabolite; xenobiotic | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methyl-2-butenal | | enal | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl 3-hydroxybutyrate | | fatty acid ethyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4,5-dimethyl-3-hydroxy-2(5h)-furanone | | butenolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-methylnicotinamide | | pyridinecarboxamide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-aminoisobutyric acid | | amino acid zwitterion; beta-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
platanic acid | | hydroxy monocarboxylic acid; methyl ketone; pentacyclic triterpenoid | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2'-deoxyuridylic acid | | deoxyuridine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-monophosphate | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
gallocatechol | | gallocatechin | antioxidant; metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-methylinosine | | inosines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydrobetulinic acid | | hydroxy monocarboxylic acid; pentacyclic triterpenoid | anti-HIV agent; antileishmanial agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bergenin | | trihydroxybenzoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-methoxyestradiol | | 17beta-hydroxy steroid; 3-hydroxy steroid | angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3'-cmp | | cytidine 3'-phosphate; pyrimidine ribonucleoside 3'-monophosphate | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xanthoxyletin | | coumarins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pinocembrin | | (2S)-flavan-4-one; dihydroxyflavanone | antineoplastic agent; antioxidant; metabolite; neuroprotective agent; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
orsellinic acid | | dihydroxybenzoic acid; resorcinols | fungal metabolite; marine metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoimperatorin | | psoralens | EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rotenolone | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
seselin | | coumarins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
perillene | | furans; monoterpenoid | fragrance; metabolite; semiochemical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycine methyl ester | | glycinyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hexadecanamide | | primary fatty amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
benzocyclobutene | | carbobicyclic compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
9-methyladenine | | methyladenine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n'-methyl-2-pyridone-5-carboxamide | | methylpyridines; pyridinecarboxamide; pyridone | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1,3-dimethyluracil | | pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methoxysalicylic acid | | methoxysalicylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1,3-dimethyluric acid | | oxopurine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucyltyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylxanthine | | 3-methylxanthine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucyl-glycyl-glycine | | tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acetylleucine | | L-leucine derivative; N-acetyl-L-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-benzoylalanine, (dl-ala)-isomer | | alanine derivative; N-acyl-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dipropylacetamide | | fatty amide | geroprotector; metabolite; teratogenic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
masoprocol | | nordihydroguaiaretic acid | antineoplastic agent; hypoglycemic agent; lipoxygenase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-methyladenine | | methyladenine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acetylisoniazid | | carbohydrazide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
illimaquinone | | monohydroxy-1,4-benzoquinones; prenylquinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
coptisine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
betulin | | diol; pentacyclic triterpenoid | analgesic; anti-inflammatory agent; antineoplastic agent; antiviral agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
narciclasine | | phenanthridines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lividomycin | | lividomycins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dmp 323 | | diazepanone; ureas | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eupolauridine | | naphthyridine derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
zaluzanin C | | gamma-lactone; guaiane sesquiterpenoid; organic heterotricyclic compound; secondary alcohol; sesquiterpene lactone | EC 1.14.13.39 (nitric oxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-aminonicotinic acid | | aminonicotinic acid; aminopyridine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(-)-catechin | | catechin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dehydrocostus lactone | | gamma-lactone; guaiane sesquiterpenoid; organic heterotricyclic compound; sesquiterpene lactone | antimycobacterial drug; antineoplastic agent; apoptosis inducer; cyclooxygenase 2 inhibitor; metabolite; trypanocidal drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Tormentic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pinobanksin | | secondary alpha-hydroxy ketone; trihydroxyflavanone | antimutagen; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sigmoidin a | | 4'-hydroxyflavanones; tetrahydroxyflavanone | anti-inflammatory agent; anti-obesity agent; antibacterial agent; metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xanthosine 5'-triphosphate | | purine ribonucleoside 5'-monophosphate; xanthosine 5'-phosphate | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
monotropein | | beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monocarboxylic acid; monosaccharide derivative | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyl-histidyl-lysine | | tripeptide | chelator; hepatoprotective agent; metabolite; vulnerary | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
homoeriodictyol | | 3'-methoxyflavanones; 4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone | flavouring agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arjunolic acid | | hydroxy monocarboxylic acid; pentacyclic triterpenoid | antibacterial agent; antifungal agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oxazolidin-2-one | | carbamate ester; oxazolidinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
monoethyl phthalate | | ethyl ester; phthalic acid monoester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methylimidazoleacetic acid | | imidazoles; monocarboxylic acid | GABA agonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-(2-aminoethyl)pyridine | | aminoalkylpyridine; primary amine | histamine agonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xanthurenic acid 8-methyl ether | | aromatic ether; monohydroxyquinoline; quinolinemonocarboxylic acid | carcinogenic agent; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl orsellinate | | hydroxybenzoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,2-di(4-methacryloxyphenyl)propane | | bisphenol; enoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sofosbuvir | | aminopyrimidine; aromatic carboxylic acid; nucleobase analogue; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methyluracil | | nucleobase analogue; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-methylcytosine | | aminopyrimidine; methylcytosine; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucyl-alanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucyl-leucyl-leucine | | tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,4-dihydroxyphenylethanol | | catechols; primary alcohol | antineoplastic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,7-dimethyluric acid | | oxopurine | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanylproline | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
d-biotin-d-sulfoxide | | biotins; sulfoxide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
biotin sulfone | | biotins; sulfone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
asperuloside | | acetate ester; beta-D-glucoside; gamma-lactone; iridoid monoterpenoid; monosaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
primin | | 1,4-benzoquinones | allergen; antifeedant; antimicrobial agent; hapten; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-(hydroxymethyl)anthraquinone | | anthraquinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tyrosylleucine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
o-methylserine | | L-serine derivative; non-proteinogenic L-alpha-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cinchonine | | (8xi)-cinchonan-9-ol; cinchona alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aucubin | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
catalpol | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,4-dihydroxyphenylglycol | | catechols; tetrol | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-methylhistamine | | aralkylamino compound; imidazoles | histamine agonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-methylhippuric acid | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taraxerol | | pentacyclic triterpenoid; secondary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-peltatin | | furonaphthodioxole; gamma-lactone; lignan; organic heterotetracyclic compound; phenols | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-acetyllupeol | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lupenone | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyltryptophan | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
monocerin | | hydroxybenzoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
propionyl-coenzyme a | | acyl-CoA | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-hydroxyisocaproic acid | | 2-hydroxy fatty acid; branched-chain fatty acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
totarol | | diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taraxerone | | scalarane sesterterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prunin protein, prunus | | (2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; flavanone 7-O-beta-D-glucoside; monosaccharide derivative | antibacterial agent; antilipemic drug; hypoglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
uvaol | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyltyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycylleucine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanyltyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyl-l-phenylalanine | | dipeptide zwitterion; dipeptide | human metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
digoxigenin-mono(digitoxoside) | | cardenolide glycoside; digitoxoside; monosaccharide derivative; steroid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thiazolidine-4-carboxylic acid, (r)-isomer | | thiazolidinemonocarboxylic acid; thioproline | geroprotector; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,6-dihydrothymine | | pyrimidone | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dehydroabietic acid | | abietane diterpenoid; carbotricyclic compound; monocarboxylic acid | allergen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
palmitone | | dialkyl ketone | anticonvulsant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-methylthymine | | methylthymine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
imidazoleacetic acid | | imidazoles; monocarboxylic acid | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-methylguanosine | | methylguanosine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanylphenylalanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
murrayanine | | carbazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
girinimbine | | carbazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tryptophylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
canthin-6-one | | enone; indole alkaloid; organic heterotetracyclic compound | antimycobacterial drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycylaspartic acid | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-methylhippuric acid | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
delta(9)-tetrahydrocannabinolic acid | | benzochromene; diterpenoid; hydroxy monocarboxylic acid; phytocannabinoid; polyketide | anti-inflammatory agent; biomarker; metabolite; neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylhippuric acid | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-glycylglutamic acid | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-caproylglycine | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diosgenin | | 3beta-sterol; hexacyclic triterpenoid; sapogenin; spiroketal | antineoplastic agent; antiviral agent; apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
s-2-aminoethyl cysteine | | L-cysteine thioether; non-proteinogenic L-alpha-amino acid | EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor; metabolite; protein synthesis inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-hydroxycyclophosphamide | | nitrogen mustard; organochlorine compound; phosphorodiamide | alkylating agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-glutamyltryptophan | | dipeptide | angiogenesis modulating agent; antineoplastic agent; immunomodulator; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
malabaricone c | | butanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
loliolide | | benzofurans | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tuberostemonine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pyrrole-3-carboxylic acid | | pyrrolecarboxylic acid | metabolite; Penicillium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
histidylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
histidinoalanine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cinchonidine | | (8xi)-cinchonan-9-ol; cinchona alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
quillaic acid | | aldehyde; hydroxy monocarboxylic acid; pentacyclic triterpenoid | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
p-methoxy-n-methylphenethylamine | | aromatic ether; secondary amino compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ecgonine methyl ester | | methyl ester; tertiary amino compound; tropane alkaloid | analgesic; central nervous system depressant; metabolite; mouse metabolite; opioid analgesic; peripheral nervous system drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetylcytidine | | acetamides; cytidines; secondary carboxamide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-hydroxydebrisoquin | | carboxamidine; isoquinolines; secondary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hypotaurine | | aminosulfinic acid; zwitterion | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hc toxin | | homodetic cyclic peptide; tetrapeptide | antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor; metabolite; phytotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
epicatechin gallate | | catechin; gallate ester; polyphenol | EC 3.2.1.1 (alpha-amylase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
versiconal hemiacetal acetate | | acetate ester; anthrafuran; lactol; palmitoyl amino acid; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
selenodiglutathione | | glutathione derivative; thioselenide | Escherichia coli metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
coprine | | cyclopropanes; dicarboxylic acid monoamide; L-glutamine derivative; non-proteinogenic L-alpha-amino acid | EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; metabolite; mycotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aristolochic acid ii | | aristolochic acids; aromatic ether; C-nitro compound; cyclic acetal; monocarboxylic acid; organic heterotetracyclic compound | carcinogenic agent; metabolite; mutagen; nephrotoxin; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
exp3174 | | biphenylyltetrazole; imidazoles; organochlorine compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ribonolactone | | butan-4-olide; ribonolactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sulfamethoxazole hydroxylamine | | isoxazoles; sulfonamide | allergen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
androsterone glucuronide | | beta-D-glucosiduronic acid; steroid glucosiduronic acid | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tephrosin | | aromatic ether; cyclic ketone; organic heteropentacyclic compound; rotenones | antineoplastic agent; metabolite; pesticide | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sapintoxin d | | phorbol ester; tertiary alpha-hydroxy ketone | fluorescent probe; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
amarogentin | | monosaccharide derivative; secoiridoid glycoside | EC 5.99.1.2 (DNA topoisomerase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taraxasterol | | pentacyclic triterpenoid; secondary alcohol | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
asiatic acid | | monocarboxylic acid; pentacyclic triterpenoid; triol | angiogenesis modulating agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
flavoglaucin | | hydroquinones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone | | benzofurans | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dioscin | | hexacyclic triterpenoid; spiroketal; spirostanyl glycoside; trisaccharide derivative | anti-inflammatory agent; antifungal agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 1.14.18.1 (tyrosinase) inhibitor; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
maculosin | | dipeptide; homodetic cyclic peptide; phenols; pyrrolopyrazine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n(4)-methylcytosine | | aminopyrimidine; methylcytosine; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetylputrescine | | N-monoacetylalkane-alpha,omega-diamine; N-substituted putrescine | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4'-demethylpodophyllotoxin | | furonaphthodioxole; organic heterotetracyclic compound; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lysicamine | | alkaloid antibiotic; oxoaporphine alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
celastrol | | monocarboxylic acid; pentacyclic triterpenoid | anti-inflammatory drug; antineoplastic agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; Hsp90 inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
procyanidin b2 | | biflavonoid; hydroxyflavan; polyphenol; proanthocyanidin | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aromadedrin | | 4'-hydroxyflavanones; dihydroflavonols; secondary alpha-hydroxy ketone; tetrahydroxyflavanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylthymine | | methylthymine; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tyrosyl-glycyl-glycine | | tripeptide zwitterion; tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclic adp-ribose | | cyclic purine nucleotide; nucleotide-sugar | metabolite; ryanodine receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycylglutamine | | dipeptide zwitterion; dipeptide | metabolite; protective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanylglutamine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
naadp | | nicotinic acid dinucleotide | calcium channel agonist; metabolite; signalling molecule | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
procyanidin b5 | | biflavonoid; hydroxyflavan; polyphenol; proanthocyanidin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
proanthocyanidin a2 | | hydroxyflavan; proanthocyanidin | angiogenesis modulating agent; anti-HIV agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydrosanguinarine | | benzophenanthridine alkaloid | antifungal agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tetrahydrocurcumin | | beta-diketone; diarylheptanoid; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eriodictyol 7-glucuronide | | 3'-hydroxyflavonoid; beta-D-glucosiduronic acid | EC 1.1.1.21 (aldehyde reductase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
beta-lipotropin, gln(9)- | | catechols; crown compound; macrocyclic lactone | bacterial metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-nitrososulfamethoxazole | | isoxazoles; nitroso compound; sulfonamide | allergen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
protosappanin a | | catechols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,3'-neotrehalosadiamine | | amino disaccharide; glycosyl glycoside derivative | antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salvinorin a | | organic heterotricyclic compound; organooxygen compound | metabolite; oneirogen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyanidin | | 5-hydroxyanthocyanidin | antioxidant; metabolite; neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
yakuchinone-a | | ketone; monomethoxybenzene; phenols | antineoplastic agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; EC 1.14.13.39 (nitric oxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
marsupsin | | 1-benzofurans; aromatic ether; polyphenol | antilipemic drug; hypoglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6,6'-bieckol | | aromatic ether; oxacycle; phlorotannin | anti-HIV-1 agent; metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylcytosine | | aminopyrimidine; methylcytosine; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eckol | | phlorotannin | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
procyanidin b3 | | biflavonoid; hydroxyflavan; polyphenol; proanthocyanidin | anti-inflammatory agent; antioxidant; EC 2.3.1.48 (histone acetyltransferase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aclacinomycin | | aminoglycoside; anthracycline; deoxy hexoside; methyl ester; monosaccharide derivative; phenols; polyketide; tertiary alcohol; tetracenequinones; zwitterion | antimicrobial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylarginine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolylarginine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-methoxytryptophan | | L-alpha-amino acid zwitterion; L-tryptophan derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylglutamate | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aspartylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aspartylglutamate | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-hydroxypipecolic acid | | piperidinemonocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolyl-tyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
histidylproline | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanyl-glycyl-glycine | | tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucylarginine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pendolmycin | | indoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
atractylenolide iii | | naphthofuran | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
malvidin | | 5-hydroxyanthocyanidin | biological pigment; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-hydroxytryptoline | | beta-carbolines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
perlolyrine | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
endocrocin | | monocarboxylic acid; phenols; trihydroxyanthraquinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sulochrin | | benzophenones; carboxylic ester; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
i-677 | | L-serine derivative; non-proteinogenic L-alpha-amino acid | antimetabolite; antimicrobial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isohomovanillic acid | | aromatic ether; phenols; phenylacetic acids | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-amino-2-methoxypyrimidine | | aminopyrimidine; aromatic ether; methylcytosine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
asimilobine | | aporphine alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aristolochic acid D | | aristolochic acids; aromatic ether; C-nitro compound; cyclic acetal; monocarboxylic acid; organic heterotetracyclic compound | carcinogenic agent; metabolite; nephrotoxin; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leukodopachrome | | hydroxy monocarboxylic acid; indoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ampelopsin | | dihydromyricetin; secondary alpha-hydroxy ketone | antineoplastic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pinusolide | | diterpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,4,5-trihydroxypentanoic acid gamma-lactone | | ribonolactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydroxysitosterol | | 3beta-hydroxy-Delta(5)-steroid; 7alpha-hydroxy steroid | metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
jolkinolide a | | diterpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
jolkinolide b | | diterpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-o-hexadecyl-2-lyso-glycero-3-phosphorylcholine | | 1-alkyl-sn-glycero-3-phosphocholine; lysophosphatidylcholine O-16:0 | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isovitexin | | C-glycosyl compound; trihydroxyflavone | EC 3.2.1.20 (alpha-glucosidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dopamine quinone | | 1,2-benzoquinones; primary amino compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
platycodin d | | triterpenoid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
frenolicin b | | benzoisochromanequinone; p-quinones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-oxopentanal | | ketoaldehyde | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
my 12-62c | | monohydroxyquinoline; quinolone | antibacterial agent; iron chelator; metabolite; signalling molecule | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,4-dihydroxyphenylpyruvic acid | | 2-oxo monocarboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
proximadiol | | eudesmane sesquiterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aristolochic acid c | | aristolochic acids; aromatic ether; C-nitro compound; cyclic acetal; monocarboxylic acid; organic heterotetracyclic compound | carcinogenic agent; metabolite; mutagen; nephrotoxin; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylacetyl-coenzyme a | | acyl-CoA | Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taxusin | | acetate ester; carbotricyclic compound; taxane diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
confertin | | cyclic ketone; gamma-lactone; organic heterotricyclic compound; pseudoguaianolide | anti-inflammatory agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
beta-methylcrotonylglycine | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tracheloside | | glycoside; lignan | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
maytenonic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
procyanidin C1 | | hydroxyflavan; polyphenol; proanthocyanidin | anti-inflammatory agent; antioxidant; EC 1.17.3.2 (xanthine oxidase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; lipoxygenase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methyleneindolenine | | indoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isopulegol | | p-menthane monoterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kadsurin | | tannin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lysylproline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-o-methylembelin | | enol ether; monohydroxy-1,4-benzoquinones | antileishmanial agent; antineoplastic agent; hepatitis C protease inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydrodaidzein | | hydroxyisoflavanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4'-o-methylepigallocatechin | | catechin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
corynoline | | benzophenanthridine alkaloid; cyclic acetal; isoquinolines; organic heterohexacyclic compound; secondary alcohol | antineoplastic agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
limonin | | epoxide; furans; hexacyclic triterpenoid; lactone; limonoid; organic heterohexacyclic compound | inhibitor; metabolite; volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dichamanetin | | diarylheptanoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
brevianamide f | | dipeptide; indoles; pyrrolopyrazine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ergolide | | acetate ester; cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone | anti-inflammatory agent; antineoplastic agent; metabolite; NF-kappaB inhibitor; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-sulfocatechol | | dihydroxybenzenesulfonic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
histidylleucine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-methoxyheptaphylline | | carbazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylserine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phellamurin | | 4'-hydroxyflavanones; beta-D-glucoside; dihydroflavonols; flavanone glycoside; monosaccharide derivative; trihydroxyflavanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolylglutamic acid | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nantenine | | oxoaporphine alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hydrastine | | isoquinolines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
butyrylcarnitine | | O-butanoylcarnitine; saturated fatty acyl-L-carnitine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-hydroxyestradiol | | 17beta-hydroxy steroid; 2-hydroxy steroid | carcinogenic agent; human metabolite; metabolite; mouse metabolite; prodrug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aromaticin | | cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone | anti-inflammatory agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acivicin | | isoxazoles; non-proteinogenic L-alpha-amino acid; organochlorine compound | antileishmanial agent; antimetabolite; antimicrobial agent; antineoplastic agent; EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor; glutamine antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-methylcorydaldine | | quinolone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-amino-3,3-dimethylbutanoic acid | | non-proteinogenic alpha-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pentabromopseudilin | | pyrroles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rocaglamide | | monocarboxylic acid amide; monomethoxybenzene; organic heterotricyclic compound | antileishmanial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dentatin | | coumarins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acronine | | acridone derivatives; alkaloid | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
enmein | | delta-lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-aminonicotinic acid | | aminonicotinic acid; aminopyridine; aromatic amine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pomolic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aglafoline | | methyl ester; organic heterotricyclic compound | metabolite; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isomaltose | | glycosylglucose | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
deoxyglucose | | 2-deoxy-D-glucose | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vestitone | | (3R)-2'-hydroxyisoflavanones; hydroxyisoflavanone; methoxyisoflavanone | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pantetheine | | pantetheines; thiol | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salicin | | aromatic primary alcohol; aryl beta-D-glucoside; benzyl alcohols | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taxifolin | | taxifolin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-formylmethionine | | L-methionine derivative; N-formyl amino acid; proteinogenic amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fucose | | deoxygalactose | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
saponarin | | C-glycosyl compound; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hippeastrine | | delta-lactone; indole alkaloid; organic heteropentacyclic compound; secondary alcohol | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyanidin 3-o-beta-d-glucopyranoside | | anthocyanin cation; beta-D-glucoside; monosaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
silychristin | | 1-benzofurans; aromatic ether; flavonolignan; polyphenol; secondary alpha-hydroxy ketone | lipoxygenase inhibitor; metabolite; prostaglandin antagonist; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
peonidin | | 5-hydroxyanthocyanidin | antineoplastic agent; antioxidant; apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
convallatoxin | | 14beta-hydroxy steroid; 19-oxo steroid; 5beta-hydroxy steroid; alpha-L-rhamnoside; steroid aldehyde; steroid lactone | metabolite; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
furostanol i | | beta-D-glucoside; cyclic hemiketal; pentacyclic triterpenoid; steroid saponin; trisaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
decursinol | | cyclic ether; delta-lactone; organic heterotricyclic compound; secondary alcohol | analgesic; antineoplastic agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
abyssinone v | | 4'-hydroxyflavanones; phenols; trihydroxyflavanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
davidigenin | | dihydrochalcones; polyphenol | anti-allergic agent; anti-asthmatic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
farrerol | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
naringin | | (2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; neohesperidoside | anti-inflammatory agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isonaringin | | (2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; rutinoside | anti-inflammatory agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cleomiscosin a | | aromatic ether; delta-lactone; organic heterotricyclic compound; phenols; primary alcohol | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vicenin ii | | C-glycosyl compound; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eugeniin | | beta-D-glucoside; ellagitannin; gallate ester; lactone | anti-HSV-1 agent; antifungal agent; antineoplastic agent; EC 3.2.1.20 (alpha-glucosidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
knipholone | | aromatic ketone; dihydroxyanthraquinone; methoxybenzenes; methyl ketone; polyphenol; resorcinols | antineoplastic agent; antioxidant; antiplasmodial drug; leukotriene antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha bitter acid | | aromatic ketone; cyclic ketone; diketone; tertiary alpha-hydroxy ketone; triol | antibacterial drug; antioxidant; cyclooxygenase 2 inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acanthoside b | | beta-D-glucoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chlorpromazine n-oxide | | organochlorine compound; phenothiazines; tertiary amine oxide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-hydroxyaspartic acid, (threo-l)-isomer | | 3-hydroxy-L-aspartic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclo(l-phe-l-pro) | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pyochelin | | monocarboxylic acid; phenols; thiazolidines | metabolite; siderophore | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
surfactin c | | cyclodepsipeptide; lipopeptide antibiotic; macrocyclic lactone | antibacterial agent; antifungal agent; antineoplastic agent; antiviral agent; metabolite; platelet aggregation inhibitor; surfactant | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
petunidin-3-glucoside | | anthocyanin cation; aromatic ether; beta-D-glucoside | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
malvidin-3-glucoside | | anthocyanin cation; aromatic ether; beta-D-glucoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dioncophylline a | | biaryl; isoquinoline alkaloid; isoquinolines; methoxynaphthalene; methylnaphthalenes; naphthalenes | antifungal agent; antimalarial; metabolite; molluscicide | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dioncophylline c | | aromatic ether; biaryl; isoquinoline alkaloid; isoquinolines; methoxynaphthalene; methylnaphthalenes; naphthols | antimalarial; antiplasmodial drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
latrunculin a | | cyclic hemiketal; macrolide; oxabicycloalkane; thiazolidinone | actin polymerisation inhibitor; metabolite; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aglucovancomycin b | | cyclic ether; heterodetic cyclic peptide; peptide antibiotic; peptide zwitterion; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(S)-ATPA | | isoxazoles; non-proteinogenic L-alpha-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
epothilone a | | epothilone; epoxide | antineoplastic agent; metabolite; microtubule-stabilising agent; tubulin modulator | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alitretinoin | | retinoic acid | antineoplastic agent; keratolytic drug; metabolite; retinoid X receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoleucylvaline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
afimoxifene | | phenols; tertiary amino compound | antineoplastic agent; estrogen receptor antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-hydroxyhippuric acid | | N-acylglycine; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
12-deoxyphorbol 13-acetate | | phorbol ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
conidendrin | | lignan | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bevirimat | | dicarboxylic acid monoester; monocarboxylic acid; pentacyclic triterpenoid | HIV-1 maturation inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
azaserine | | carboxylic ester; diazo compound; L-serine derivative; non-proteinogenic L-alpha-amino acid | antifungal agent; antimetabolite; antimicrobial agent; antineoplastic agent; glutamine antagonist; immunosuppressive agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
16beta,17-dihydroxy-ent-kaurane-19-oic acid | | bridged compound; diol; ent-kaurane diterpenoid; hydroxy monocarboxylic acid; primary alcohol; tertiary alcohol | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyrin | | aromatic ether; coumarins; hydroxyisoflavans | antibacterial agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
reynosin | | organic heterotricyclic compound; sesquiterpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
moronic acid | | pentacyclic triterpenoid | anti-HIV agent; anti-HSV-1 agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
maltitol | | alpha-D-glucoside; glycosyl alditol | laxative; metabolite; sweetening agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Phe-Tyr | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-acetyl-1-pyrroline | | acylimine; methyl ketone; pyrroline | flavouring agent; Maillard reaction product; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl indole-3-carboxylate | | indoles; methyl ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
camalexin | | 1,3-thiazoles; indole phytoalexin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
komaroviquinone | | bridged compound; lactol; p-quinones; tetracyclic diterpenoid | metabolite; trypanocidal drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-hydroxycinnamic acid | | 2-coumaric acid; phenols | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
16-epivincamine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diethyl fumarate | | diester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoliquiritigenin | | chalcones | antineoplastic agent; biological pigment; EC 1.14.18.1 (tyrosinase) inhibitor; GABA modulator; geroprotector; metabolite; NMDA receptor antagonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-acetyl-beta-carboline | | harmala alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
propolin c | | 4'-hydroxyflavanones; tetrahydroxyflavanone | metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xanthohumol | | aromatic ether; chalcones; polyphenol | anti-HIV-1 agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
butylidenephthalide | | 2-benzofurans; gamma-lactone | EC 3.2.1.20 (alpha-glucosidase) inhibitor; hypoglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
malonyl coenzyme a | | malonyl-CoAs | EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor; Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
imidazol-1-ylacetic acid | | imidazolyl carboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
captax | | aryl thiol; benzothiazoles | carcinogenic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetyltryptophan | | L-tryptophan derivative; N-acetyl-L-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cinnamoylglycine | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-benzoylalanine | | N-acyl-L-alanine; N-benzoylalanine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoferulic acid | | ferulic acids | antioxidant; biomarker; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oxypeucadanin, (r)-(+)-isomer | | furanocoumarin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
curcumin | | aromatic ether; beta-diketone; diarylheptanoid; enone; polyphenol | anti-inflammatory agent; antifungal agent; antineoplastic agent; biological pigment; contraceptive drug; dye; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; flavouring agent; food colouring; geroprotector; hepatoprotective agent; immunomodulator; iron chelator; ligand; lipoxygenase inhibitor; metabolite; neuroprotective agent; nutraceutical; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thiouracil | | nucleobase analogue; thiocarbonyl compound | antithyroid drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
allylthiourea | | thioureas | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-glycylalanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
caryophyllene oxide | | epoxide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fumonisin b1 | | diester; fumonisin; primary amino compound; triol | carcinogenic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
olivetolic acid | | benzoic acids; monocarboxylic acid; polyketide; resorcinols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hirsutine, (16e,20beta)-isomer | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Ganodermanontriol | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dieckol | | aromatic ether; oxacycle; phlorotannin | anticoagulant; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycylproline | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tamoxifen n-oxide | | aromatic ether; tertiary amine oxide | anti-estrogen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-deacetylgedunin | | cyclic terpene ketone; delta-lactone; enone; epoxide; furans; limonoid; pentacyclic triterpenoid | anti-inflammatory agent; antimalarial; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
galactose-6-phosphate | | D-galactose 6-phosphate | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nicotine n-glucuronide | | iminium betaine; N-glycosylpyridine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isorhyncophylline | | indolizines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cysteinylproline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycyllysine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methionyltryptophan | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ascorbigen | | indolyl carbohydrate | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pimeloyl-coenzyme a | | omega-carboxyacyl-CoA | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1-salicylate glucuronide | | benzoic acids; beta-D-glucosiduronic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoschaftoside | | C-glycosyl compound; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
croomine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-hydroxyflavanone | | 3'-hydroxyflavanones; monohydroxyflavanone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ungeremine | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
seryl-proline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-hydroxy-5-methyl-3(2h)-furanone | | cyclic ketone; enol; furans | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
annomontine | | alkaloid; aminopyrimidine; beta-carbolines | antiparasitic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
8-hydroxymanzamine a | | alkaloid; beta-carbolines; isoquinolines | anti-HSV-2 agent; EC 2.7.11.26 (tau-protein kinase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ginkgetin | | biflavonoid; hydroxyflavone; methoxyflavone; ring assembly | anti-HSV-1 agent; antineoplastic agent; cyclooxygenase 2 inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
calceolarioside b | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eupatilin | | dihydroxyflavone; trimethoxyflavone | anti-inflammatory agent; anti-ulcer drug; antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
quercetin 3-o-glucuronide | | beta-D-glucosiduronic acid; quercetin O-glycoside | antidepressant; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
australifungin | | carbobicyclic compound; enol; enone; secondary alcohol | antifungal agent; EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor; HIV-1 integrase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
catechin gallate | | flavans; gallate ester; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sterigmatocystin | | sterigmatocystins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,7-dimethoxy-5,3',4'-trihydroxyflavone | | dimethoxyflavone; trihydroxyflavone | EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apigenin | | trihydroxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7,3'-dihydroxy-4'-methoxyisoflavone | | 4'-methoxyisoflavones; 7-hydroxyisoflavones | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
calcitriol | | D3 vitamins; hydroxycalciol; triol | antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vomifoliol | | (6S)-vomifoliol | metabolite; phytotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
feruloyltyramine | | tyramines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
luteolin-7-glucuronide | | glycosyloxyflavone; luteolin O-glucuronoside; monosaccharide derivative; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chrysoeriol | | monomethoxyflavone; trihydroxyflavone | antineoplastic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
quercetin 3-o-methyl ether | | monomethoxyflavone; tetrahydroxyflavone | antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dexmedetomidine | | trihydroxyflavone; trimethoxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apigetrin | | beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative | antibacterial agent; metabolite; non-steroidal anti-inflammatory drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rutin | | disaccharide derivative; quercetin O-glucoside; rutinoside; tetrahydroxyflavone | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-ketoprostaglandin e1 | | prostaglandins E | metabolite; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lipoxin a4 | | hydroxy polyunsaturated fatty acid; lipoxin; long-chain fatty acid | human metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
harmine | | harmala alkaloid | anti-HIV agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
naringenin chalcone | | chalcones; polyphenol | anti-allergic agent; anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cornexistin | | cyclic dicarboxylic anhydride; organic heterobicyclic compound; secondary alpha-hydroxy ketone | herbicide; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isobavachalcone | | chalcones; polyphenol | antibacterial agent; metabolite; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
daphnoretin | | aromatic ether; hydroxycoumarin | antineoplastic agent; antiviral agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Rhynchophylline | | indolizines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
esculin | | beta-D-glucoside; hydroxycoumarin | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mammeisin | | neoflavonoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ostruthin | | terpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
costunolide | | germacranolide; heterobicyclic compound | anthelminthic drug; antiinfective agent; antineoplastic agent; antiparasitic agent; antiviral drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
caryophyllene | | beta-caryophyllene | fragrance; insect attractant; metabolite; non-steroidal anti-inflammatory drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phaseic acid | | alpha,beta-unsaturated monocarboxylic acid; apo carotenoid sesquiterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
agathisflavone | | biaryl; biflavonoid; hydroxyflavone | antineoplastic agent; antiviral agent; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cupressuflavone | | biflavonoid; hydroxyflavone; ring assembly | EC 3.4.21.37 (leukocyte elastase) inhibitor; metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fisetin | | 3'-hydroxyflavonoid; 7-hydroxyflavonol; tetrahydroxyflavone | anti-inflammatory agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
genkwanin | | dihydroxyflavone; monomethoxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bellidifolin | | polyphenol; xanthones | EC 3.1.1.7 (acetylcholinesterase) inhibitor; hypoglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
demethylbellidifolin | | tetrol; xanthones | antioxidant; EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite; mutagen; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hinokiflavone | | aromatic ether; biflavonoid; hydroxyflavone | antineoplastic agent; metabolite; neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
euxanthone | | phenols; xanthones | metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylquercetin | | 7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone | anticoagulant; EC 1.14.18.1 (tyrosinase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
norswertianolin | | beta-D-glucoside; xanthones | EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
swerchirin | | aromatic ether; phenols; xanthones | hypoglycemic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoscutellarein | | tetrahydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kaempferide | | 7-hydroxyflavonol; monomethoxyflavone; trihydroxyflavone | antihypertensive agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
morin | | 7-hydroxyflavonol; pentahydroxyflavone | angiogenesis modulating agent; anti-inflammatory agent; antibacterial agent; antihypertensive agent; antineoplastic agent; antioxidant; EC 5.99.1.2 (DNA topoisomerase) inhibitor; hepatoprotective agent; metabolite; neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
norwogonin | | trihydroxyflavone | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
orientin | | 3'-hydroxyflavonoid; C-glycosyl compound; tetrahydroxyflavone | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
patuletin | | flavonols; monomethoxyflavone; pentahydroxyflavone | analgesic; antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor; lipoxygenase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rhamnetin | | monomethoxyflavone; tetrahydroxyflavone | anti-inflammatory agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
robustaflavone | | biflavonoid; hydroxyflavone; ring assembly | anti-HBV agent; antineoplastic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
scutellarein | | tetrahydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tamarixetin | | 7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tricetin | | pentahydroxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tricin | | 3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
astringin | | beta-D-glucoside; monosaccharide derivative; polyphenol; stilbenoid | antineoplastic agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
polydatin | | beta-D-glucoside; monosaccharide derivative; polyphenol; stilbenoid | anti-arrhythmia drug; antioxidant; geroprotector; hepatoprotective agent; metabolite; nephroprotective agent; potassium channel modulator | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
epsilon-viniferin | | 1-benzofurans; polyphenol; stilbenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
irilone | | hydroxyisoflavone; organic heterotricyclic compound; oxacycle | antineoplastic agent; immunomodulator; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
caffeic acid phenethyl ester | | alkyl caffeate ester | anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiviral agent; immunomodulator; metabolite; neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
licoisoflavone a | | 7-hydroxyisoflavones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prunetin | | 7-methoxyisoflavones; hydroxyisoflavone | anti-inflammatory agent; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
wedelolactone | | aromatic ether; coumestans; delta-lactone; polyphenol | antineoplastic agent; apoptosis inducer; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; hepatoprotective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rottlerin | | aromatic ketone; benzenetriol; chromenol; enone; methyl ketone | anti-allergic agent; antihypertensive agent; antineoplastic agent; apoptosis inducer; K-ATP channel agonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
syringetin | | 3',5'-dimethoxyflavone; 3'-methoxyflavones; 7-hydroxyflavonol; dimethoxyflavone; tetrahydroxyflavone | metabolite; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
10-deoxymethynolide | | macrolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4',7-dihydroxyflavone | | dihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rhoifolin | | dihydroxyflavone; glycosyloxyflavone; neohesperidoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
veronicastroside | | disaccharide derivative; glycosyloxyflavone; neohesperidoside; trihydroxyflavone | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
quercimeritrin | | beta-D-glucoside; flavonols; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone | antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
josamycin | | acetate ester; aldehyde; disaccharide derivative; glycoside; macrolide antibiotic; tertiary alcohol; tertiary amino compound | antibacterial drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n,n-dimethylsphingenine | | aminodiol; sphingoid; tertiary amino compound | EC 2.7.1.91 (sphingosine kinase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-hydroxyestradiol | | 4-hydroxy steroid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
9-hydroxy-10,12-octadecadienoic acid | | HODE; octadecadienoic acid | human metabolite; metabolite; mouse metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
9-oxo-10,12-octadecadienoic acid | | enone; oxooctadecadienoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
13-oxo-9,11-octadecadienoic acid | | 13-oxo-9,11-octadecadienoic acid; oxo fatty acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
13,14-dihydro-15-ketoprostaglandin d2 | | prostaglandins D | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
15-keto-13,14-dihydroprostaglandin f2alpha | | ketone; prostaglandins Falpha | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,3-dinor-6-ketoprostaglandin f1alpha | | 4-oxo monocarboxylic acid; prostanoid; secondary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ergosta-7,22-dien-3-ol, (3beta,5alpha,6alpha,22e)-isomer | | 3beta-sterol | anti-HSV-1 agent; antifungal agent; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
calcifediol | | D3 vitamins; diol; hydroxycalciol | bone density conservation agent; human metabolite; metabolite; mouse metabolite; nutraceutical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclosporine | | homodetic cyclic peptide | anti-asthmatic drug; anticoronaviral agent; antifungal agent; antirheumatic drug; carcinogenic agent; dermatologic drug; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; geroprotector; immunosuppressive agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oleyl alcohol | | fatty alcohol 18:1; long-chain primary fatty alcohol | metabolite; nonionic surfactant | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fortimicin a | | amino cyclitol glycoside; aminoglycoside antibiotic; diol; monocarboxylic acid amide; primary amino compound | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3',4',7-trihydroxyisoflavone | | 7-hydroxyisoflavones | antineoplastic agent; EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6,7,4'-trihydroxyisoflavone | | 7-hydroxyisoflavones | anti-inflammatory agent; antimutagen; EC 1.14.18.1 (tyrosinase) inhibitor; metabolite; PPARalpha agonist; PPARgamma agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
15-deoxy-delta(12,14)-prostaglandin j2 | | prostaglandins J | electrophilic reagent; insulin-sensitizing drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cytochalasin b | | cytochalasin; lactam; lactone; organic heterotricyclic compound | actin polymerisation inhibitor; metabolite; mycotoxin; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ciguatoxins | | ciguatoxin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
12-hydroxy-5,8,10-heptadecatrienoic acid | | hydroxy polyunsaturated fatty acid; long-chain fatty acid; trienoic fatty acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bisdemethoxycurcumin | | beta-diketone; diarylheptanoid; enone; polyphenol | EC 3.2.1.1 (alpha-amylase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
clausine e | | carbazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ethyl caffeate | | alkyl caffeate ester; ethyl ester; hydroxycinnamic acid | anti-inflammatory agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
heptaphylline | | carbazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pellitorine | | fatty amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
andrographolide | | carbobicyclic compound; gamma-lactone; labdane diterpenoid; primary alcohol; secondary alcohol | anti-HIV agent; anti-inflammatory drug; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isorhamnetin-3-o-galactoside | | beta-D-galactoside; glycosyloxyflavone; monomethoxyflavone; monosaccharide derivative; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isorhamnetin 3-o-glucoside | | beta-D-glucoside; glycosyloxyflavone; monomethoxyflavone; monosaccharide derivative; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kaempferol-3-o-rutinoside | | disaccharide derivative; kaempferol O-glucoside; rutinoside; trihydroxyflavone | metabolite; plant metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ligustilide | | butenolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7,4'-dihydroxy-3'-methoxyisoflavone | | 7-hydroxyisoflavones; methoxyisoflavone | antiplasmodial drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sappanchalcone | | catechols; chalcones; monomethoxybenzene | anti-allergic agent; anti-inflammatory agent; antioxidant; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methyl brevifolincarboxylate | | cyclic ketone; delta-lactone; organic heterotricyclic compound; phenols | EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; metabolite; platelet aggregation inhibitor; radical scavenger; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-deoxysappanchalcone | | chalcones; monomethoxybenzene; phenols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nostocarboline | | alkaloid; beta-carbolines; organic cation; organochlorine compound | antimalarial; EC 3.1.1.8 (cholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ergosterol-5,8-peroxide | | 3beta-sterol; ergostanoid; organic peroxide; phytosterols | antimycobacterial drug; antineoplastic agent; metabolite; trypanocidal drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-(4-hydroxy-3-methoxyphenyl)-n-(2-(4-hydroxy-3-methoxyphenyl)ethyl)-2-propenamide | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
macluraxanthone b | | phenols; xanthones | anti-HIV agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
flavokawain b | | chalcones; dimethoxybenzene; phenols | anti-inflammatory agent; antileishmanial agent; antineoplastic agent; apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alternariol | | benzochromenone; phenols | EC 3.1.1.8 (cholinesterase) inhibitor; metabolite; mycotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cis-3-hexenyl acetate | | acetate ester; olefinic compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pipercallosidine | | alkaloid; benzodioxoles; enamide; secondary carboxamide | apoptosis inducer; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-(4-hydroxy-beta-phenethyl)-4-hydroxycinnamide | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-hydroxyisoflavone | | 7-hydroxyisoflavones | EC 1.14.14.14 (aromatase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
flazin | | harmala alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
11-hydroxynoracronycine | | acridines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
jaceosidin | | dimethoxyflavone; trihydroxyflavone | anti-allergic agent; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,7,3'-trihydroxy-3,4'-dimethoxyflavone | | dimethoxyflavone; trihydroxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salutaridine | | morphinane alkaloid | anti-HBV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cytochalasin e | | cytochalasan alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
artocarpin lectin | | monomethoxyflavone; trihydroxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fumarates | | butenedioate; C4-dicarboxylate | human metabolite; metabolite; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bleomycin | | bleomycin | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
1,7-dihydroxy-4-methoxyxanthone | | aromatic ether; phenols; xanthones | metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
demethoxycurcumin | | beta-diketone; diarylheptanoid; enone; polyphenol | anti-inflammatory agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bergamottin | | furanocoumarin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanyl-alanyl-alanine | | tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
24-ethyl-4-cholesten-3-one | | C29-steroid; steroid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
myricetin 3-o-glucuronide | | monosaccharide derivative; myricetin O-glucuronide; pentahydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylalanine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpinumisoflavone | | isoflavanones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-aspartylalanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanyltyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arglabin | | epoxide; gamma-lactone; organic heterotetracyclic compound; sesquiterpene lactone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
quercetin 7-rhamnoside | | alpha-L-rhamnoside; flavonols; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
albonoursin | | 2,5-diketopiperazines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oroidin | | pyrroles; secondary carboxamide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
monorden | | cyclic ketone; enone; epoxide; macrolide antibiotic; monochlorobenzenes; phenols | antifungal agent; metabolite; tyrosine kinase inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apratoxin a | | 1,3-thiazoles; apratoxin | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(-)-catechin-3-O-gallate | | flavans; gallate ester; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aspartyllysine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arginyllysine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hygromycin a | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
latrunculin b | | cyclic hemiketal; macrolide; oxabicycloalkane; thiazolidinone | actin polymerisation inhibitor; metabolite; toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
falcarindiol | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dehydroergosterol | | 3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols | biomarker; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-oleoylglycine | | fatty amide; N-acylglycine 18:1 | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rhizoxin | | 1,3-oxazoles; epoxide; macrolide antibiotic | antimitotic; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
manoalide | | butenolide; lactol; sesterterpenoid | EC 3.1.1.4 (phospholipase A2) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
concanamycin a | | carbamate ester; concanamycin | antifungal agent; EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid | | enoate ester; methyl ester; monocarboxylic acid amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thunberginol f | | catechols; gamma-lactone; isobenzofuranone | metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pyracrenic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eicosa-11,14-dienoic acid, (z,z)-isomer | | icosadienoic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
yuanhuadine | | diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
tiglylglycine | | N-acylglycine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rhodiocyanoside a | | aliphatic nitrile; beta-D-glucoside; cyanogenic glycoside; monosaccharide derivative | anti-allergic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(2E,4E)-N-isobutyl-2,4-dodecadienamide | | fatty amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mycothiazole | | thiazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
13-oxo-9,11-octadecadienoic acid | | 13-oxo-9,11-octadecadienoic acid | metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
linderalactone | | butenolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pros-methylimidazoleacetic acid | | imidazolyl carboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cellobionic acid | | carbohydrate acid; disaccharide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pseudopteroxazole | | tetralins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sophoraflavanone a | | (2S)-flavan-4-one; 4'-hydroxyflavanones; trihydroxyflavanone | antibacterial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
panduratin a | | diarylheptanoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
stigmasterol 3-o-beta-d-glucopyranoside | | beta-D-glucoside; monosaccharide derivative; phytosterols; steroid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
17-hydroxyjolkinolide b | | diterpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sq-23377 | | cyclic ether; enol; polyunsaturated fatty acid; very long-chain fatty acid | calcium ionophore; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
corosolic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclo(prolyl-valyl) | | piperazinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucyl-phenylalanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glutamylalanine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glutaminyl-glycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methionylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
valylleucine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanyl-valine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclo(glycyltryptophyl) | | indoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alanylglycine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
valyltyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alpha-glutamyltryptophan | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lysylglutamic acid | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methionylglutamic acid | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
seryl-histidine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arginyl-glutamine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanylproline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lysylglycine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycylhistidine | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kopsinine | | indole alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclo(leucyl-phenylalanyl) | | 2,5-diketopiperazines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolylisoleucine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
phenylalanyl-valine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
isoleucyl-tyrosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolyl-serine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
grayanotoxin i | | acetate ester; pentol; secondary alcohol; tertiary alcohol; tetracyclic diterpenoid | antihypertensive agent; metabolite; neuromuscular agent; phytotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
19-norandrosterone | | 17-oxo steroid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
s-allylcysteine | | L-alpha-amino acid zwitterion; S-hydrocarbyl-L-cysteine | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
oleandrigenin | | 14beta-hydroxy steroid; 3beta-hydroxy steroid; steroid ester | EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
valyl-prolyl-proline | | tripeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
prolylvaline | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
palbinone | | 16-oxo steroid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pseurotin | | azaspiro compound; lactam; oxaspiro compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
gambogic acid | | pyranoxanthones | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xenovulene a | | cyclic ether; enone; organic heterotetracyclic compound; sesquiterpenoid | GABA antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
fr 148083 | | aromatic ether; macrolide; phenols; secondary alcohol; secondary alpha-hydroxy ketone | antibacterial agent; antineoplastic agent; metabolite; NF-kappaB inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
LL-Z1640-1 | | macrolide; resorcinols | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
9-methoxycanthin-6-one | | aromatic ether; indole alkaloid; organic heterotetracyclic compound | antineoplastic agent; antiplasmodial drug; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
n-acetylcarnosine | | dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cholest-5-en-3-one | | 3-oxo-Delta(5)-steroid; cholestanoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kaempferol 3-O-beta-L-glucopyranoside | | beta-L-glucoside; flavonols; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rubraxanthone | | aromatic ether; polyphenol; xanthones | antibacterial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ubiquinol | | polyprenylhydroquinone; ubiquinol | biomarker; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
landomycin a | | oligosaccharide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ancistroealaine a | | aromatic ether; biaryl; isoquinoline alkaloid; isoquinolines; methoxynaphthalene; methylnaphthalenes | antileishmanial agent; antiplasmodial drug; metabolite; trypanocidal drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cerberin | | acetate ester; cardenolide glycoside; monosaccharide derivative | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
actein | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
araloside a | | triterpenoid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ageladine a | | alkaloid; aromatic amine; imidazopyridine; organobromine compound; pyrroles | angiogenesis inhibitor; antineoplastic agent; matrix metalloproteinase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
corynoxine b | | indolizines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kaempferol 7-o-glucoside | | beta-D-glucoside; flavonols; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone | metabolite; plant metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
delphinidin 3-sambubioside | | anthocyanidin 3-O-beta-D-sambubioside | apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nodosin | | delta-lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
protylonolide | | diol; enone; macrolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
arisugacin | | aromatic ether; delta-lactone; enone; organic heterotetracyclic compound; tertiary alcohol | antimicrobial agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite; Penicillium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nymphaeol c | | 4'-hydroxyflavanones; tetrahydroxyflavanone | metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thonningianin a | | tannin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cephalostatin i | | oxo steroid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
papyriflavonol a | | 3'-hydroxyflavonoid; flavonols; pentahydroxyflavone | EC 1.14.18.1 (tyrosinase) inhibitor; EC 3.1.1.4 (phospholipase A2) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lactonamycin | | gamma-lactone; organic heterohexacyclic compound; phenols; trideoxyhexose derivative | antibacterial agent; antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
myrsinoic acid b | | 1-benzofurans; monocarboxylic acid | anti-inflammatory agent; EC 4.4.1.11 (methionine gamma-lyase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
betulone | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eckstolonol | | organic heteropentacyclic compound; oxacycle; phlorotannin | metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
manassantin b | | benzodioxoles; dimethoxybenzene; lignan; oxolanes; secondary alcohol | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
gitaloxin | | cardenolide glycoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
paeonilide | | benzoate ester | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydroxanthohumol | | aromatic ether; dihydrochalcones; polyphenol | EC 1.14.13.39 (nitric oxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
corynoxine | | indolizines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-phloroeckol | | aromatic ether; phlorotannin | antioxidant; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside | | beta-D-glucoside; dimethoxybenzene; lignan; monosaccharide derivative; polyphenol; primary alcohol; tetralins | antibacterial agent; antifungal agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Sphaeropsidin C | | tricyclic diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
kelampayoside a | | glycoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside | | aromatic ether; benzyl alcohols; beta-D-glucoside; monosaccharide derivative; primary alcohol | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,3-dihydro-3beta-methoxy withaferin A | | 27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; secondary alcohol; withanolide | metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nigranoic acid | | dicarboxylic acid; tetracyclic triterpenoid | antineoplastic agent; HIV-1 reverse transcriptase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
esculeoside a | | azaspiro compound; oxaspiro compound; saponin; steroid alkaloid; steroid saponin | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
aerothionin | | isoxazoles | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
artemisic acid | | carbobicyclic compound; monocarboxylic acid; octahydronaphthalenes; sesquiterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
26-deoxyactein | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5-formylcytosine | | aminopyrimidine; heteroarenecarbaldehyde; nucleobase analogue; pyrimidone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
migrastatin | | ether; macrolide antibiotic; piperidones; secondary alcohol | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Lyngbic acid | | long-chain fatty acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9h-xanthen-9-one | | polyphenol; xanthones | anti-inflammatory agent; antineoplastic agent; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bielschowskysin | | acetate ester; cyclic acetal; diterpenoid; gamma-lactone; organic heterohexacyclic compound | antimalarial; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
procyanidin b1 | | biflavonoid; hydroxyflavan; polyphenol; proanthocyanidin | anti-inflammatory agent; EC 3.4.21.5 (thrombin) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cyclo(tyrosyl-tyrosyl) | | cyclo(tyrosyl-tyrosyl) | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
spiculoic acid a | | carbobicyclic compound; cyclic ketone; oxo monocarboxylic acid; styrenes | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
myrocin a | | tertiary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3'-o-methylepicatechin | | catechin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
episilvestrol | | dioxanes; ether; methyl ester; organic heterotricyclic compound | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
protopanaxatriol | | 12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; 6alpha-hydroxy steroid; sapogenin; tetracyclic triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
laurinterol | | organobromine compound; phenols; sesquiterpenoid | antibacterial agent; apoptosis inducer; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Pseudopterosin G-J aglycone | | diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ceratamine a | | alkaloid; aromatic ether; cyclic ketone; organic heterobicyclic compound; organobromine compound; secondary amino compound; tertiary amine | antimitotic; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
liphagal | | aldehyde; cyclic ether; meroterpenoid; organic heterotetracyclic compound; polyphenol | EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pulsatilla saponin d | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diversonol | | phenols; tertiary alcohol | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
neotuberostemonine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
drymaritin | | enol ether; enone; indole alkaloid; organic heterotetracyclic compound | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lyoniresinol | | dimethoxybenzene; lignan; polyphenol; primary alcohol; tetralins | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
silvestrol | | dioxanes; ether; methyl ester; organic heterotricyclic compound | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ginsenoside ro | | triterpenoid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diosgenin glucoside | | hexacyclic triterpenoid; monosaccharide derivative; spiroketal; sterol 3-beta-D-glucoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pyripyropene a | | organic heterotetracyclic compound; sesquiterpenoid | acyl-CoA:cholesterol acyltransferase 2 inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-epioleanolic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leucylproline | | dipeptide zwitterion; dipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
R-(-)-actinodaphnine | | aporphine alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cytotrienin a | | cyclopropanecarboxylate ester; ether; hydroquinones; lactam; macrocycle; secondary alcohol | antibacterial agent; antimicrobial agent; antineoplastic agent; apoptosis inducer; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
methylamphotericin b | | macrolide; methyl ester; monosaccharide derivative | antifungal agent; antiinfective agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2'-methoxykurarinone | | 4'-hydroxyflavanones; dihydroxyflavanone; dimethoxyflavanone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
verproside | | glycoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
verminoside | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
minecoside | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(R)-(+)-6',7'-dihydroxybergamottin | | furanocoumarin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lapidilectine b | | indolyl carboxylic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
batzelladine a | | alkaloid; carboxylic ester; guanidines; organic heterotricyclic compound; pyrrolopyrimidine; triazaacenaphthylene | anti-HIV-1 agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alloin | | anthracenes; C-glycosyl compound; cyclic ketone; phenols | laxative; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
longipinene | | alpha-longipinene | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
parkeol | | 3beta-hydroxy-4,4-dimethylsteroid; 3beta-sterol; tetracyclic triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rutundic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
a-factor (streptomyces) | | butan-4-olide; primary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
taraxasteryl acetate | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chikusetsu saponin iva | | triterpenoid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
xestoaminol c | | amino alcohol; sphingoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
malyngamide A | | dicarboximide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
simalikalactone D | | cyclic ether; delta-lactone; enone; organic heteropentacyclic compound; quassinoid; secondary alcohol; secondary alpha-hydroxy ketone; triol | antimalarial; antineoplastic agent; antiviral agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
friedelane | | triterpene | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
shamixanthone | | cyclic ketone; phenols; pyranoxanthene | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
17,18-epoxy-5,8,11,14-eicosatetraenoic acid | | EpETE | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chaetominine | | indole alkaloid; lactam; organic heterotetracyclic compound; quinazolines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
schweinfurthin g | | cyclic ether; organic heterotricyclic compound; resorcinols; stilbenoid | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salmon calcitonin | | heterodetic cyclic peptide; peptide hormone; polypeptide | bone density conservation agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
complestatin | | cyclic ether; heterodetic cyclic peptide; indoles; organic heterobicyclic compound; organochlorine compound; peptide antibiotic; polyphenol | anti-HIV-1 agent; antimicrobial agent; HIV-1 integrase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
neuroprotectin a | | cyclic ether; heterodetic cyclic peptide; indoles; organochlorine compound; polyphenol | HIV-1 integrase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alx-0600 | | polypeptide | antioxidant; glucagon-like peptide-2 receptor agonist; metabolite; protective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
schweinfurthin f | | cyclic ether; organic heterotricyclic compound; resorcinols; stilbenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
antrocamphin a | | methoxybenzenes | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
respirantin | | benzamides; cyclodepsipeptide; formamides; phenols | antimicrobial agent; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
streptobiosamine | | amino disaccharide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
interiotherin b | | aromatic ether; fatty acid ester; lignan; organic heteropentacyclic compound; oxacycle | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
succinyladenosine | | adenosines; amino dicarboxylic acid; L-aspartic acid derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-tuliposide a | | 6-O-acyl-D-glucose; homoallylic alcohol | allergen; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
glycochenodeoxycholate-3-sulfate | | 7alpha-hydroxy steroid; bile acid glycine conjugate; steroid sulfate | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
wewakazole | | cyclic peptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
spongia-13(16),14-dien-19-oic acid | | cyclic ether; monocarboxylic acid; tetracyclic diterpenoid | androgen antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Icariside E4 | | benzofurans | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lucidenic acid n | | cyclic terpene ketone; dioxo monocarboxylic acid; secondary alcohol; tetracyclic triterpenoid | antineoplastic agent; EC 3.1.1.8 (cholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dihydroagarofuran | | bridged compound; cyclic ether; eudesmane sesquiterpenoid; organic heterotricyclic compound | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
23-epi-26-deoxyactein | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
23-hydroxybetulinic acid | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(1S,3aR,4S,6S,6aS,9aS,9bS)-9a-isocyano-6-(2-isocyano-2-methylpropyl)-1,4-dimethyl-7-methylidene-2,3,3a,4,5,6,6a,8,9,9b-decahydro-1H-phenalene | | diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
bromophycolide a | | diterpenoid; macrolide; organobromine compound; phenols; tertiary alcohol | anti-HIV agent; antibacterial agent; antifungal agent; antimalarial; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-acetamidoglucal | | acetamides; glycal derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
diorcinol | | aromatic ether; phenols | fungal metabolite; marine metabolite; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
caribenol a | | organic heterotetracyclic compound; terpene lactone; tertiary alcohol | antimalarial; antitubercular agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
halisulfate 1 | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-O-feruloylcatalpol | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
grassypeptolide | | cyclodepsipeptide; macrocycle | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
essramycin | | triazolopyrimidines | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ainsliadimer a | | sesquiterpene lactone; spiro compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salvileucalin b | | bridged compound; diterpenoid; furans; gamma-lactone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ciliatamide a | | caprolactams; lipopeptide | antileishmanial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
etnangien | | hydroxy monocarboxylic acid; macrolide antibiotic | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
latrunculol a | | macrolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
N-trans-sinapoyltyramine | | hydroxycinnamic acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lycojapodine a | | alkaloid; bridged compound; cyclic ketone; lactone; organic heterotetracyclic compound | anti-HIV-1 agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
epi-maslinic acid | | dihydroxy monocarboxylic acid; pentacyclic triterpenoid | anti-inflammatory agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eoxin c4 | | eoxin; leukotriene | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
brartemicin | | benzoate ester; glycosyl glycoside derivative; resorcinols | antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Majusculamide AB | | amino acid amide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7,8-dihydroxyflavanone | | dihydroxyflavanone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
antcin a | | ergostanoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
integric acid | | carboxylic ester; cyclic ketone; dioxo monocarboxylic acid; enal; enone; eremophilane sesquiterpenoid | HIV-1 integrase inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vanilloloside | | glycoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2,3-dihydro-3beta-O-sulfate withaferin A | | 27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; steroid sulfate; withanolide | antineoplastic agent; metabolite; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dicranin | | acetylenic fatty acid; long-chain fatty acid; straight-chain fatty acid; trienoic fatty acid | antibacterial agent; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leachianone a | | 4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone | antimalarial; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
hordatine a | | aromatic ether; benzofurans; dicarboxylic acid diamide; guanidines; phenols | adrenergic antagonist; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
englerin a | | cinnamate ester; glycolate ester; guaiane sesquiterpenoid | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
monanchocidin | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eurycomanone | | cyclic ether; delta-lactone; enone; organic heteropentacyclic compound; pentol; quassinoid; secondary alcohol; secondary alpha-hydroxy ketone; tertiary alcohol | antimalarial; antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sphaeropsidin a | | gamma-lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
gardenoside | | beta-D-glucoside; cyclopentapyran; enoate ester; methyl ester; monosaccharide derivative; tertiary alcohol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
landomycin d | | anthraquinone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | | 11-oxo steroid; 12alpha-hydroxy steroid; 3alpha-hydroxy steroid; 7-oxo steroid; monocarboxylic acid; secondary alpha-hydroxy ketone; steroid acid | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
antcin k | | bile acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | | 11-oxo steroid; 3alpha-hydroxy steroid; 7-oxo steroid; monocarboxylic acid; steroid acid | antineoplastic agent; cholinergic antagonist; metabolite; serotonergic antagonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
shizukaol B | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
shizukaol f | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
calicheamicin gamma(1)i | | calicheamicin; enediyne antibiotic; organoiodine compound | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
staphyloxanthin | | apo carotenoid triterpenoid; D-aldohexose derivative; fatty acid ester; triol; xanthophyll | antioxidant; biological pigment; metabolite; virulence factor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sm 1 peptide | | acetate ester; ergot alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
mycocyclosin | | 2,5-diketopiperazines; organic heterotetracyclic compound; polyphenol | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
callipeltin a | | cyclodepsipeptide; guanidines; lactone; oligopeptide; phenols | anti-HIV-1 agent; antifungal agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
vinylamycin | | cyclodepsipeptide; macrocycle; primary alcohol | antibacterial agent; antimicrobial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
promegestone | | terpene lactone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lancifodilactone g | | cyclic ether; diol; enol; gamma-lactone; oxaspiro compound; triterpenoid | anti-HIV agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rediocide a | | diterpenoid; epoxide; ortho ester; terpene lactone | insecticide; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lasiokaurin | | kaurane diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
longikaurin a | | kaurane diterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ponicidin | | dioxanes | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
(Z)-6,6',7,3'a-Diligustilide | | butenolide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
suvanine | | organic molecular entity | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
shizukaol d | | triterpenoid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
thailandepsin a | | cyclodepsipeptide | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nordidemnin b | | didemnin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4-formylaminooxyvinylglycine | | non-proteinogenic alpha-amino acid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
platycoside e | | triterpenoid saponin | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
leuconoxine | | alkaloid | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
epidermin | | macrocycle; type A lantibiotic | antibacterial agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
surfactin A | | cyclodepsipeptide; lipopeptide antibiotic; macrocyclic lactone | antibacterial agent; antifungal agent; antineoplastic agent; antiviral agent; metabolite; surfactant | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
myriaporone 3 | | beta-hydroxy ketone; epoxide; lactol; oxanes; primary alcohol; secondary alcohol | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
avenacoside b | | beta-D-glucoside; hexacyclic triterpenoid; spiroketal; steroid saponin; tetrasaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3-methylglutarylcarnitine | | O-methylglutarylcarnitine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pivaloylcarnitine | | C5-acylcarnitine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
levoleucovorin | | 5-formyltetrahydrofolic acid | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7,8-dihydroneopterin | | dihydropterin; neopterins | Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
guanosine monophosphate | | guanosine 5'-phosphate; purine ribonucleoside 5'-monophosphate | biomarker; Escherichia coli metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-amino-4-oxo-6-acetyl-7,8-dihydro-3h,9h-pyrimidodiazepine | | methyl ketone; pyrimidodiazepine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dyspropterin | | biopterins; tetrahydropterin | human metabolite; metabolite; mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2'-o-methylguanosine | | methylguanosine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
allopurinol riboside | | nucleoside analogue | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
norclozapine | | dibenzodiazepine; organochlorine compound; piperazines | delta-opioid receptor agonist; metabolite; serotonergic antagonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-methylguanosine | | methylguanosine; organic cation | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
3'-o-methylguanosine | | methylguanosine | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
primapterin | | biopterins | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7-methylinosine | | inosines; organic cation | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
marineosin a | | azaspiro compound; ether; macrocycle; oxaspiro compound; pyrroles | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
marineosin b | | azaspiro compound; ether; macrocycle; oxaspiro compound; pyrroles | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |