spironolactone has been researched along with Osteoporosis in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bisphosphonate, tetracycline and spironolactone use has been shown to increase gastro-oesophageal inflammation, an accepted risk factor for cancer." | 3.85 | The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data. ( Busby, J; Cardwell, CR; Iversen, L; Lee, AJ; Murchie, P; Murray, L; Spence, A; Watson, MC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amar, J | 1 |
| Angoulvant, T | 1 |
| Boivin, JM | 1 |
| Amar, L | 1 |
| Lantelme, P | 1 |
| Blacher, J | 1 |
| Plu-Bureau, G | 1 |
| Vehier, CM | 1 |
| Busby, J | 1 |
| Murchie, P | 1 |
| Murray, L | 1 |
| Iversen, L | 1 |
| Lee, AJ | 1 |
| Spence, A | 1 |
| Watson, MC | 1 |
| Cardwell, CR | 1 |
| Tragl, KH | 1 |
| Gaborit, P | 1 |
| Dobbels, E | 1 |
| Bonnefoy-Cudraz, M | 1 |
| Roux, H | 1 |
| Prezelj, J | 1 |
| Kocijancic, A | 1 |
1 review available for spironolactone and Osteoporosis
| Article | Year |
|---|---|
Topics: Age Factors; Antihypertensive Agents; Blood Pressure; Breast Neoplasms; Female; Humans; Hypertension | 2019 |
4 other studies available for spironolactone and Osteoporosis
| Article | Year |
|---|---|
The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data.
Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Esophageal Neoplasms; Female; Humans; Inflammation; | 2017 |
[Iatrogenic and environmentally caused diseases of the endocrine system in the aged].
Topics: Aged; Cortisone; Cushing Syndrome; Digitalis Glycosides; Endocrine System Diseases; Environmental Ex | 1983 |
[Osteoporosis and prolonged administration of antialdosterone drugs. Histomorphometric study].
Topics: Adult; Calcifediol; Calcium; Drug Administration Schedule; Female; Fractures, Spontaneous; Humans; H | 1983 |
Comment on spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.
Topics: Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Osteoporosis; Spironola | 1999 |