tannins has been researched along with Osteoporosis* in 2 studies
2 other study(ies) available for tannins and Osteoporosis
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The effect of tannic acid on bone mechanical and geometric properties, bone density, and trabecular histomorphometry as well as the morphology of articular and growth cartilages in rats co-exposed to cadmium and lead is dose dependent.
Cadmium (Cd) and lead (Pb) are toxic elements that accumulate to the largest extent in bones. Rats were used to investigate whether tannic acid (TA; 0.5%, 1.0%, 1.5%. 2.0%, or 2.5%) would have a protective effect on the structure and properties of bones in the case of exposure to Cd and Pb (diet: 7 mg Cd/kg and 50 mg Pb/kg) for 6 weeks. The effects of administration of TA in Cd- and Pb-poisoned rats on bone characteristics and the morphology of articular and growth cartilages were determined. All the rats administered Cd and Pb had an enhanced Cd and Pb concentration in blood plasma and bone and reduced bone Ca content irrespective of the TA administration. Cd and Pb alone reduced the mechanical endurance and histomorphometric parameters of trabecular bone and the thickness of the growth plate and articular cartilage. Tannic acid improved cancellous bone parameters in the rat exposed to Cd and Pb. A diet rich in TA improved articular cartilage constituents in heavy metal-poisoned rats. These results suggest that alimentary TA supplementation can counteract in a dose-dependent manner some of the destructive changes evoked by Cd and Pb possibly by reducing the exposure. Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Density Conservation Agents; Cadmium; Cadmium Poisoning; Calcium; Cancellous Bone; Cartilage, Articular; Dose-Response Relationship, Drug; Growth Plate; Lead; Lead Poisoning; Male; Osteomalacia; Osteoporosis; Protective Agents; Random Allocation; Rats, Wistar; Tannins; Toxicokinetics | 2017 |
New hydrolysable tannin from Cibotium barometz.
To study the chemical constituents from Cibotium batometz.. Column chromatograph and HPLC were used to isolate and purify the compound, and the structure was elucidated on the basis of MS and NMR spectroscopic methods.. A new phenolic compound, 4-O-caffeoyl-D-glucopyranose, has been isolated from the rhizome of C. barometz. The structure of the new compound was elucidated on the basis of chemical and spectroscopic methods, including intensive 1D, 2D NMR and ESI-MS data analysis.. 4-O-caffeoyl-D-glucopyranose was a new phenolic compound. Topics: Drugs, Chinese Herbal; Ferns; Hydrolysis; Osteoporosis; Rhizome; Tannins | 2013 |