methylmalonic acid has been researched along with Osteoporosis in 4 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous data suggest that elevated serum total homocysteine (tHcy) may be a risk factor for bone fracture and osteoporosis." | 3.81 | B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States. ( Bailey, RL; Eicher-Miller, HA; Fakhouri, TH; Fan, R; Gahche, JJ; Looker, AC; Lu, Z; Mills, JL; Weaver, CM, 2015) |
| " Serum vitamin B12 was related to BMD in dose-response fashion up to about 200 pmol/L, and subjects with serum Hcy > or = 20 micromol/L had significantly lower BMD than subjects with serum Hcy < 10 micromol/L." | 1.33 | Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. ( Jacques, PF; Morris, MS; Selhub, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, RL | 1 |
| Looker, AC | 1 |
| Lu, Z | 1 |
| Fan, R | 1 |
| Eicher-Miller, HA | 1 |
| Fakhouri, TH | 1 |
| Gahche, JJ | 1 |
| Weaver, CM | 1 |
| Mills, JL | 1 |
| Vaes, BL | 1 |
| Lute, C | 1 |
| Blom, HJ | 1 |
| Bravenboer, N | 1 |
| de Vries, TJ | 1 |
| Everts, V | 1 |
| Dhonukshe-Rutten, RA | 2 |
| Müller, M | 1 |
| de Groot, LC | 2 |
| Steegenga, WT | 1 |
| Lips, M | 1 |
| de Jong, N | 1 |
| Chin A Paw, MJ | 1 |
| Hiddink, GJ | 1 |
| van Dusseldorp, M | 1 |
| van Staveren, WA | 1 |
| Morris, MS | 1 |
| Jacques, PF | 1 |
| Selhub, J | 1 |
4 other studies available for methylmalonic acid and Osteoporosis
| Article | Year |
|---|---|
B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States.
Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Creatinine; Cross-Sectional Studies; Female; | 2015 |
Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid.
Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Cell Differentiation; Cell Line; Cell Prolif | 2009 |
Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Body Composition; Body Height; Body Weight; Bone De | 2003 |
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans.
Topics: Aged; Bone Density; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Methylmalonic Acid; Osteopo | 2005 |