methoxsalen has been researched along with Osteoporosis in 4 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methoxsalen (MTS) is a natural bioactive compound found in a variety of plants that has many known biofunctions; however, its effects on osteoporosis and related mechanisms are not clear." | 3.85 | Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice. ( Choi, RY; Ham, JR; Hwang, YH; Kim, MJ; Lee, MK; Yee, ST, 2017) |
| " The phototoxicity of bergapten as a side effect should be further avoided." | 2.72 | Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity. ( Cao, Y; Dai, X; Li, X; Liang, Y; Liu, K; Lu, J; Wang, X; Xie, L; Zhang, X, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, Y | 1 |
| Xie, L | 1 |
| Liu, K | 1 |
| Cao, Y | 1 |
| Dai, X | 1 |
| Wang, X | 1 |
| Lu, J | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Ham, JR | 1 |
| Choi, RY | 1 |
| Yee, ST | 1 |
| Hwang, YH | 1 |
| Kim, MJ | 1 |
| Lee, MK | 1 |
| Xiao, JJ | 1 |
| Zhao, WJ | 1 |
| Zhang, XT | 1 |
| Zhao, WL | 1 |
| Wang, XX | 1 |
| Yin, SH | 1 |
| Jiang, F | 1 |
| Zhao, YX | 1 |
| Chen, FN | 1 |
| Li, SL | 1 |
| Li, XJ | 1 |
| Zhu, Z | 1 |
| Han, SL | 1 |
| Zhang, ZL | 1 |
1 review available for methoxsalen and Osteoporosis
| Article | Year |
|---|---|
Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity.
Topics: 5-Methoxypsoralen; Anti-Inflammatory Agents; Humans; Methoxsalen; Osteoporosis; Ultraviolet Rays | 2021 |
3 other studies available for methoxsalen and Osteoporosis
| Article | Year |
|---|---|
Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice.
Topics: Animals; Biomarkers; Body Weight; Bone and Bones; Bone Density; Core Binding Factor Alpha 1 Subunit; | 2017 |
Bergapten promotes bone marrow stromal cell differentiation into osteoblasts in vitro and in vivo.
Topics: 5-Methoxypsoralen; Alkaline Phosphatase; Animals; beta Catenin; Bone Marrow Cells; Cell Differentiat | 2015 |
Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice.
Topics: 5-Methoxypsoralen; Animals; Anti-Inflammatory Agents; Biomarkers; Diabetes Complications; Disease Mo | 2016 |