Page last updated: 2024-10-21

phenytoin and Osteoporosis

phenytoin has been researched along with Osteoporosis in 10 studies

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

ExcerptRelevanceReference
"Markers of bone formation and bone resorption were determined in serum and urine."1.31Long-term anticonvulsant therapy leads to low bone mineral density--evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells. ( Becker, A; Feldkamp, J; Scharff, D; Scherbaum, WA; Witte, OW, 2000)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ensrud, KE1
Walczak, TS1
Blackwell, T1
Ensrud, ER1
Bowman, PJ1
Stone, KL1
Seymour, HM1
Glendenning, P1
Onodera, K2
Kuribayashi, Y1
Takahashi, A2
Baars, A1
Baars, M1
Beier, R1
Bretschneider, T1
Feldkamp, J1
Becker, A1
Witte, OW1
Scharff, D1
Scherbaum, WA1
Mayanagi, H1
Wakabayashi, H1
Kamei, J1
Shinoda, H1
Johnell, O1
Nilsson, BE1
Wallöe, A1
Wiklund, PE1
Maclay, E1
Hadden, DR1
McIlrath, EM1
Nesbitt, GS1
Lam, SY1
Evans, JH1
Quinn, MA1
Baker, HW1
Latorre, H1
Kenny, FM1

Other Studies

10 other studies available for phenytoin and Osteoporosis

ArticleYear
Antiepileptic drug use increases rates of bone loss in older women: a prospective study.
    Neurology, 2004, Jun-08, Volume: 62, Issue:11

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Bone Density; Bone Diseases, Metabolic; Calcaneus; Calcium

2004
Fit for a fracture.
    The Medical journal of Australia, 2005, Aug-15, Volume: 183, Issue:4

    Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fract

2005
[An animal model of antiepileptic-induced osteoporosis in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:5

    Topics: Animals; Anticonvulsants; Bone Density; Disease Models, Animal; Isoxazoles; Osteoporosis; Phenytoin;

2006
[Diagnosis of osteopathy caused by antiepileptic drugs].
    Zeitschrift fur arztliche Fortbildung, 1981, Aug-01, Volume: 75, Issue:15

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Han

1981
Long-term anticonvulsant therapy leads to low bone mineral density--evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2000, Volume: 108, Issue:1

    Topics: Absorptiometry, Photon; Adult; Amino Acids; Anticonvulsants; Bone Density; Bone Resorption; Carbamaz

2000
Phenytoin-induced bone loss and its prevention with alfacalcidol or calcitriol in growing rats.
    Calcified tissue international, 2001, Volume: 69, Issue:2

    Topics: Animals; Body Weight; Bone Density; Bone Diseases, Metabolic; Calcitriol; Hydroxycholecalciferols; M

2001
Bone morphology in epileptics.
    Calcified tissue international, 1979, Oct-31, Volume: 28, Issue:2

    Topics: Adult; Aged; Bone and Bones; Bone Diseases; Bone Resorption; Epilepsy; Female; Humans; Male; Middle

1979
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
    The Ulster medical journal, 1978, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalci

1978
Postpartum spinal wedge fractures in a 27-year-old epileptic anorectic woman.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1987, Volume: 27, Issue:1

    Topics: Adult; Anorexia Nervosa; Epilepsy, Tonic-Clonic; Female; Fractures, Spontaneous; Humans; Osteoporosi

1987
High-dosage intravenous calcium therapy for osteoporosis and osteomalacia in anticonvulsant therapy with hypomobilization.
    Pediatrics, 1974, Volume: 53, Issue:1

    Topics: Alkaline Phosphatase; Calcium; Child; Child, Preschool; Female; Humans; Infant; Osteomalacia; Osteop

1974