indomethacin has been researched along with Osteoporosis in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kynurenines were analysed by HPLC." | 5.33 | Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment. ( Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006) |
| " Here, we compared the analgesic effect of an ointment containing 1% diphenhydramine (a typical first-generation antihistaminic drug) with that of indomethacin (a typical non-steroidal anti-inflammatory drug) in elderly patients with osteoarthritis and/or osteoporosis who complained of bone-joint-muscle pain." | 5.17 | Prompt analgesic effect of antihistaminic diphenhydramine ointment on bone-joint-muscle pain as assessed by skin impedance. ( Endo, Y; Fujii, Y; Fujita, T; Jotoku, T; Miyauchi, A; Ohue, M; Takagi, Y; Tsuchiya, M, 2013) |
| "Kynurenines were analysed by HPLC." | 1.33 | Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment. ( Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, T | 1 |
| Ohue, M | 1 |
| Fujii, Y | 1 |
| Jotoku, T | 1 |
| Miyauchi, A | 1 |
| Takagi, Y | 1 |
| Tsuchiya, M | 1 |
| Endo, Y | 1 |
| Cankaya, D | 1 |
| Tabak, Y | 1 |
| Ozturk, AM | 1 |
| Gunay, MC | 1 |
| Forrest, CM | 1 |
| Mackay, GM | 1 |
| Oxford, L | 1 |
| Stoy, N | 1 |
| Stone, TW | 1 |
| Darlington, LG | 1 |
| Sturtridge, WC | 1 |
| Kolodny, AL | 1 |
| Klipper, AR | 1 |
| McBeath, AA | 1 |
| Schoutens, A | 1 |
| Verhas, M | 1 |
| Dourov, N | 1 |
| Bergmann, P | 1 |
| Caulin, F | 1 |
| Verschaeren, A | 1 |
| Mone, M | 1 |
| Heilporn, A | 1 |
| Leung, DY | 1 |
| Key, L | 1 |
| Steinberg, JJ | 1 |
| Young, MC | 1 |
| Von Deck, M | 1 |
| Wilkinson, R | 1 |
| Geha, RS | 1 |
| Suchomel, J | 1 |
| Beran, J | 1 |
| Carson, RW | 1 |
| Cohn, P | 1 |
| Levinson, JE | 1 |
| Plotz, CM | 1 |
| Sanchez, RC | 1 |
| Smyth, CJ | 1 |
| Ward, JR | 1 |
| Weiss, T | 1 |
| Bätzner, K | 1 |
| Beck, W | 1 |
| Wever, H | 1 |
| Motawakel, AG | 1 |
1 trial available for indomethacin and Osteoporosis
| Article | Year |
|---|---|
Prompt analgesic effect of antihistaminic diphenhydramine ointment on bone-joint-muscle pain as assessed by skin impedance.
Topics: Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Elect | 2013 |
11 other studies available for indomethacin and Osteoporosis
| Article | Year |
|---|---|
Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats.
Topics: Absorptiometry, Photon; Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, | 2015 |
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
Topics: 3-Hydroxyanthranilic Acid; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethac | 2006 |
Pharmacology and therapeutics of bone.
Topics: Animals; Bone Resorption; Calcitonin; Calcium; Cyclic AMP; Endotoxins; Glucocorticoids; Humans; Hydr | 1975 |
Bone and joint diseases in the elderly.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Age Factors; Aged; Anti-Inflammatory Agents; Ar | 1976 |
The aging skeleton. Osteoporosis and degenerative arthritis.
Topics: Age Factors; Aged; Aspirin; Estrogens; Female; Fracture Fixation; Humans; Ibuprofen; Indomethacin; J | 1975 |
Bone loss and bone blood flow in paraplegic rats treated with calcitonin, diphosphonate, and indomethacin.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Diphosphonates; Female; Indomethacin; | 1988 |
Increased in vitro bone resorption by monocytes in the hyper-immunoglobulin E syndrome.
Topics: Aspirin; Bone Resorption; Child; Child, Preschool; Dinoprostone; Female; Humans; Hydroxyproline; Hyp | 1988 |
[Transient osteoporosis of the hip joint].
Topics: Adult; Female; Hip Joint; Humans; Indomethacin; Osteoporosis; Pregnancy; Pregnancy Complications; Ti | 1973 |
Unremitting disease in a young mother.
Topics: Adult; Arthritis, Rheumatoid; Depression; Female; Humans; Indomethacin; Osteoporosis; Phenylbutazone | 1972 |
[Complications and problems of total arthroplasty of the hip joint].
Topics: Acrylates; Biomechanical Phenomena; Calcinosis; Embolism; Femoral Fractures; Hip; Humans; Indomethac | 1972 |
[Gout in dermatology].
Topics: Adolescent; Aged; Colchicine; Diagnosis, Differential; Gout; Humans; Indomethacin; Joint Diseases; M | 1969 |