chloroquine has been researched along with Osteoporosis in 5 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Icariin (ICA) has shown potential osteoprotective effects." | 1.51 | Icariin promotes osteogenic differentiation of bone marrow stromal cells and prevents bone loss in OVX mice via activating autophagy. ( Cai, L; Hou, Z; Li, S; Liang, X; Xie, Y; Yan, F; Zhu, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, X | 1 |
| Hou, Z | 1 |
| Xie, Y | 1 |
| Yan, F | 1 |
| Li, S | 1 |
| Zhu, X | 1 |
| Cai, L | 1 |
| Xiu, Y | 1 |
| Xu, H | 1 |
| Zhao, C | 1 |
| Li, J | 1 |
| Morita, Y | 1 |
| Yao, Z | 1 |
| Xing, L | 1 |
| Boyce, BF | 1 |
| Lin, NY | 1 |
| Chen, CW | 1 |
| Kagwiria, R | 1 |
| Liang, R | 1 |
| Beyer, C | 1 |
| Distler, A | 1 |
| Luther, J | 1 |
| Engelke, K | 1 |
| Schett, G | 1 |
| Distler, JH | 1 |
| Hamel, P | 1 |
| Abed, E | 1 |
| Brissette, L | 1 |
| Moreau, R | 1 |
| Miehle, W | 1 |
5 other studies available for chloroquine and Osteoporosis
| Article | Year |
|---|---|
Icariin promotes osteogenic differentiation of bone marrow stromal cells and prevents bone loss in OVX mice via activating autophagy.
Topics: Animals; Autophagy; Cell Differentiation; Chloroquine; Female; Flavonoids; Flow Cytometry; Fluoresce | 2019 |
Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.
Topics: Animals; Apoptosis Regulatory Proteins; Beclin-1; Bone Resorption; Cells, Cultured; Chloroquine; Fem | 2014 |
Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss.
Topics: Animals; Autophagy; Autophagy-Related Protein 7; Cells, Cultured; Chloroquine; Disease Models, Anima | 2016 |
Characterization of oxidized low-density lipoprotein-induced hormesis-like effects in osteoblastic cells.
Topics: Animals; Apoptosis; Atherosclerosis; Cell Line; Cell Proliferation; Chloroquine; Humans; Lipoprotein | 2008 |
[The Reiter syndrome. 2. Diagnosis, therapy, prognosis].
Topics: Arthritis; Arthritis, Reactive; Chloroquine; Gold; Humans; Immunosuppressive Agents; Osteoporosis; P | 1979 |