prednisone and Osteoporosis studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

Excerpt	Relevance	Reference
"To determine the effect of alendronate (ALN) and teriparatide on trabecular bone score (TBS) in patients with glucocorticoid-induced osteoporosis."	9.22	Trabecular Bone Score in Patients With Chronic Glucocorticoid Therapy-Induced Osteoporosis Treated With Alendronate or Teriparatide. ( Agnusdei, D; Alam, J; Hans, D; Kohlmeier, LA; Krohn, KD; Leib, ES; MacLaughlin, EJ; Marcus, R; Saag, KG; Simonelli, C; Taylor, KA, 2016)
"This study aims to describe effects on BMD of treatment according to EULAR guidelines with a methotrexate-based tight control strategy including 10 mg prednisone daily versus the same strategy without prednisone in early RA patients who received preventive therapy for osteoporosis."	9.17	Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? ( Bakker, MF; Bijlsma, JW; Jacobs, JW; Jurgens, MS; van der Goes, MC; van der Veen, MJ; van der Werf, JH; Welsing, PM, 2013)
"This study summarizes the treatment effect of zoledronic acid infusion on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis."	9.16	Post hoc analysis of a single IV infusion of zoledronic acid versus daily oral risedronate on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis. ( Bucci-Rechtweg, C; Devogelaer, JP; Lau, CS; Papanastasiou, P; Reginster, JY; Reid, DM; Roux, C; Saag, K; Sambrook, PN; Su, G, 2012)
"To determine the effect of alendronate on glucocorticoid-induced osteoporosis(GIO)."	9.14	[Effect of alendronate on glucocorticoid-induced osteoporosis]. ( Li, Q; Shi, C; Zou, X, 2009)
"Prednisone, 10 mg/d, provides clinical benefit, particularly in the first 6 months, and substantially inhibits progression of radiologic joint damage in patients with early active rheumatoid arthritis and no previous treatment with disease-modifying antirheumatic drugs."	9.10	Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial. ( Bijlsma, JW; Jacobs, JW; Siewertsz Van Reesema, DR; van Everdingen, AA, 2002)
"The objectives were to determine the efficacy and safety of nasal salmon calcitonin 200 IU daily in the prevention of corticosteroid-induced osteoporosis."	9.08	Salmon calcitonin nasal spray in the prevention of corticosteroid-induced osteoporosis. ( Adachi, JD; Bell, MJ; Bensen, WG; Bianchi, FA; Cividino, AA; Craig, GL; Gent, M; Gordon, M; Roberts, R; Sebaldt, RJ; Steele, M; Sturtridge, WC; Themeles, E; Tugwell, P, 1997)
"To determine the effects of low dose methotrexate (MTX) on bone mineral density (BMD) of patients with rheumatoid arthritis (RA)."	9.08	Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. ( Buckley, LM; Cartularo, KS; Cooper, SM; Leib, ES; Vacek, PM, 1997)
"Eighteen male and 21 female patients who had established corticosteroid-induced osteoporosis and were receiving chronic prednisone therapy (> or = 10 mg/d) were enrolled in a prospective 12-month, open-label study."	9.08	Cyclical etidronate reverses bone loss of the spine and proximal femur in patients with established corticosteroid-induced osteoporosis. ( Mulder, H; Snelder, AA; Struys, A, 1995)
"The long-term effects of high dose steroid treatment with either prednisone (PDN) or deflazacort (DFZ) were examined on various parts of the skeleton in 29 patients with nephrotic syndrome."	9.07	Glucocorticoid-induced osteoporosis in the lumbar spine, forearm, and mandible of nephrotic patients: a double-blind study on the high-dose, long-term effects of prednisone versus deflazacort. ( Brandi, L; Daugaard, H; Egfjord, M; Lewin, E; Olgaard, K; Storm, T; van Wowern, N, 1992)
"To determine whether primary care physicians (osteopathic and allopathic) are evaluating and treating adult patients at risk for osteoporosis secondary to long-term prednisone use."	7.73	Prednisone-induced osteoporosis: an overlooked and undertreated adverse effect. ( Gecys, GT; Shah, SK, 2006)
"Cyclosporine, a potent immunosuppressive drug, has been suggested to be beneficial in the treatment of some immune-mediated dermatoses, including pemphigus."	7.69	The efficacy of combined treatment with prednisone and cyclosporine in patients with pemphigus: preliminary study. ( Ben-Amitai, D; David, M; Katzenelson, V; Lapidoth, M; Lustig, S; Sandbank, M, 1994)
"The effect of long-acting medroxyprogesterone acetate (MPA) on the trabecular bone density in patients with glucocorticoid-induced osteoporosis (GCO) was evaluated."	7.68	Effective therapy of glucocorticoid-induced osteoporosis with medroxyprogesterone acetate. ( Grecu, EO; Simmons, R; Weinshelbaum, A, 1990)
"Long-acting medroxyprogesterone acetate (MPA) effect on some important parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis (GCO) was evaluated."	7.68	Effects of medroxyprogesterone acetate on some parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis. ( Baylink, DJ; Grecu, EO; Haloran, BP; Simmons, R; Spencer, ME, 1991)
"Prednisone-induced osteoporosis is very frequent in the long-term treatment of sarcoidosis (sarcoidosis 4:45-48, 1987)."	7.67	Bone protection with salmon calcitonin (sCT) in the long-term steroid therapy of chronic sarcoidosis. ( Montemurro, L; Rizzato, G; Schiraldi, G; Sisti, S; Tosi, G; Zanni, D, 1988)
"Synthetic 1alpha-hydroxycholecalciferol, a potent vitamin D analogue, was given daily together with calcium to seven patients with senile osteoporosis and to three patients with prednisone-induced bone loss."	7.65	Effect of 1alpha-hydroxycholecalciferol in senile osteoporosis and in bone loss following prednisone treatment. ( Andersen, RB; Friis, TH; Hjorth, L; Kjaer, I; Lund, B; Reimann, I; Sorensen, OH, 1977)
"Osteoporosis is a common complication of long-term glucocorticoid therapy for which there is no well-proved preventive or restorative treatment."	6.69	Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. ( Brown, JP; Czachur, M; Daifotis, AG; Delmas, PD; Emkey, R; Goemaere, S; Hawkins, F; Liberman, UA; Malice, MP; Saag, KG; Schnitzer, TJ; Thamsborg, G, 1998)
"Osteoporosis is a recognized complication of corticosteroid therapy."	6.68	Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis. ( Adachi, JD; Bensen, WG; Brown, J; Chines, AA; Hanley, D; Hodsman, A; Josse, R; Kendler, DL; Lentle, B; Olszynski, W; Ste-Marie, LG; Tenenhouse, A, 1997)
"To determine the effect of alendronate (ALN) and teriparatide on trabecular bone score (TBS) in patients with glucocorticoid-induced osteoporosis."	5.22	Trabecular Bone Score in Patients With Chronic Glucocorticoid Therapy-Induced Osteoporosis Treated With Alendronate or Teriparatide. ( Agnusdei, D; Alam, J; Hans, D; Kohlmeier, LA; Krohn, KD; Leib, ES; MacLaughlin, EJ; Marcus, R; Saag, KG; Simonelli, C; Taylor, KA, 2016)
" zoledronic acid (ZOL) versus oral risedronate (RIS), on bone turnover markers (BTMs) in subjects with glucocorticoid-induced osteoporosis (GIO)."	5.17	Effect on bone turnover markers of once-yearly intravenous infusion of zoledronic acid versus daily oral risedronate in patients treated with glucocorticoids. ( Bucci-Rechtweg, C; Collette, J; Devogelaer, JP; Goemaere, S; Ish-Shalom, S; Papanastasiou, P; Reginster, JY; Reid, DM; Sambrook, P; Su, G, 2013)
"This study aims to describe effects on BMD of treatment according to EULAR guidelines with a methotrexate-based tight control strategy including 10 mg prednisone daily versus the same strategy without prednisone in early RA patients who received preventive therapy for osteoporosis."	5.17	Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? ( Bakker, MF; Bijlsma, JW; Jacobs, JW; Jurgens, MS; van der Goes, MC; van der Veen, MJ; van der Werf, JH; Welsing, PM, 2013)
"This study summarizes the treatment effect of zoledronic acid infusion on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis."	5.16	Post hoc analysis of a single IV infusion of zoledronic acid versus daily oral risedronate on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis. ( Bucci-Rechtweg, C; Devogelaer, JP; Lau, CS; Papanastasiou, P; Reginster, JY; Reid, DM; Roux, C; Saag, K; Sambrook, PN; Su, G, 2012)
"To determine the effect of alendronate on glucocorticoid-induced osteoporosis(GIO)."	5.14	[Effect of alendronate on glucocorticoid-induced osteoporosis]. ( Li, Q; Shi, C; Zou, X, 2009)
" Adult patients (>21 years old) with early RA (symptom duration <1 year) and severe joint pain under maximal dose of nonsteroidal anti-inflammatory drugs (NSAIDS) were started on low-dose prednisone (10 mg/day)."	5.11	Bone mineral density in patients with early rheumatoid arthritis treated with corticosteroids. ( Habib, GS; Haj, S, 2005)
"Prednisone, 10 mg/d, provides clinical benefit, particularly in the first 6 months, and substantially inhibits progression of radiologic joint damage in patients with early active rheumatoid arthritis and no previous treatment with disease-modifying antirheumatic drugs."	5.10	Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial. ( Bijlsma, JW; Jacobs, JW; Siewertsz Van Reesema, DR; van Everdingen, AA, 2002)
"The objectives were to determine the efficacy and safety of nasal salmon calcitonin 200 IU daily in the prevention of corticosteroid-induced osteoporosis."	5.08	Salmon calcitonin nasal spray in the prevention of corticosteroid-induced osteoporosis. ( Adachi, JD; Bell, MJ; Bensen, WG; Bianchi, FA; Cividino, AA; Craig, GL; Gent, M; Gordon, M; Roberts, R; Sebaldt, RJ; Steele, M; Sturtridge, WC; Themeles, E; Tugwell, P, 1997)
"Nine adult patients 31-47 (median 39) years of age treated with prednisone and cyclosporin A (CsA) for chronic graft-versus-host disease (GVHD) were evaluated for biochemical factors associated with skeletal turnover at initiation of immunosuppressive therapy (3 months after marrow transplant) and 9 months later (follow-up)."	5.08	Bone density loss during treatment of chronic GVHD. ( Aker, SN; Bruemmer, B; Chesnut, CH; Lenssen, PS; Sanders, J; Stern, JM; Sullivan, KM, 1996)
"To determine the effects of low dose methotrexate (MTX) on bone mineral density (BMD) of patients with rheumatoid arthritis (RA)."	5.08	Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. ( Buckley, LM; Cartularo, KS; Cooper, SM; Leib, ES; Vacek, PM, 1997)
"Eighteen male and 21 female patients who had established corticosteroid-induced osteoporosis and were receiving chronic prednisone therapy (> or = 10 mg/d) were enrolled in a prospective 12-month, open-label study."	5.08	Cyclical etidronate reverses bone loss of the spine and proximal femur in patients with established corticosteroid-induced osteoporosis. ( Mulder, H; Snelder, AA; Struys, A, 1995)
"The long-term effects of high dose steroid treatment with either prednisone (PDN) or deflazacort (DFZ) were examined on various parts of the skeleton in 29 patients with nephrotic syndrome."	5.07	Glucocorticoid-induced osteoporosis in the lumbar spine, forearm, and mandible of nephrotic patients: a double-blind study on the high-dose, long-term effects of prednisone versus deflazacort. ( Brandi, L; Daugaard, H; Egfjord, M; Lewin, E; Olgaard, K; Storm, T; van Wowern, N, 1992)
" Steps to prevent or treat osteoporosis should be considered in all patients who take the equivalent of prednisone at a dose of 2."	5.05	Glucocorticoid-induced osteoporosis: Insights for the clinician. ( Hayat, S; Magrey, MN, 2020)
"A 66-year-old woman treated by alendronate for her osteoporosis was investigated."	4.31	Orbital myositis induced by alendronate: A case report. ( Biver, E; Caruso, A; Fayolle, D; Lefeuvre, L, 2023)
"In the past, patients with rheumatoid arthritis (RA) were treated with monotherapy with conventional drugs, such as sulfasalazine, methotrexate, and intramuscular gold, which often leads to persistent arthritis, loss of functional capacity, and decreased quality of life."	3.80	Are glucocorticoids harmful to bone in early rheumatoid arthritis? ( Lems, WF, 2014)
" Rheumatology providers of patients 40+, on prednisone, with no record of BMD testing in the past 2 years, were targeted with the message: 'This patient is at risk for osteoporosis due to prednisone use."	3.75	Development, implementation and evaluation of an electronic medical record prompt for bone density testing. ( Amundson, JH; Jackson, JM; Rolnick, SJ, 2009)
"To determine whether primary care physicians (osteopathic and allopathic) are evaluating and treating adult patients at risk for osteoporosis secondary to long-term prednisone use."	3.73	Prednisone-induced osteoporosis: an overlooked and undertreated adverse effect. ( Gecys, GT; Shah, SK, 2006)
"Disease duration and cumulative dose of prednisone in children with polyarticular JIA are risk factors of stunted growth and decreased QUS values of bone quality."	3.73	Quantitative ultrasonometry of the calcaneus in children with juvenile idiopathic arthritis. ( Bayer, M; Dolezalova, P; Kutilek, S; Nemcova, D, 2006)
"Cheng Zai Wan ([symbol: see text]), a Chinese herbal preparation was administrated in the two-leg rat model of aseptic necrosis of the femoral head established by taking prednisone acetate for a long period and the osteoporosis model rat by castration in order to explore the effects of the prescription on necrosis of the femoral head."	3.72	Experimental study on cheng zai wan for treatment of necrosis of the femoral head. ( Chen, Y; Huang, H; Huang, K; Huang, Y; Lang, F; Zhang, W; Zhou, C, 2003)
" Fifty-six per cent of patients met osteoporotic criteria; a greater proportion of patients treated with prednisone had osteoporosis compared with those an hydrocortisone."	3.72	Long-term follow-up of bone mineral density in Addison's disease. ( Hawkins, F; Jara, A; Jódar, E; Martinez, G; Valdepeñas, MP, 2003)
"We identified patients aged > or = 20 years who received prescriptions for > or = 2 g of prednisone (or equivalent) during any 12-month period between January 1, 1998, and December 31, 1999, and who initiated use of osteoporosis-specific drugs (alendronate sodium, etidronate disodium, and calcitonin) during that period."	3.71	Prevalence and determinants of osteoporosis drug prescription among patients with high exposure to glucocorticoid drugs. ( Chidambaran, P; Ettinger, B; Pressman, A, 2001)
"Cyclosporine, a potent immunosuppressive drug, has been suggested to be beneficial in the treatment of some immune-mediated dermatoses, including pemphigus."	3.69	The efficacy of combined treatment with prednisone and cyclosporine in patients with pemphigus: preliminary study. ( Ben-Amitai, D; David, M; Katzenelson, V; Lapidoth, M; Lustig, S; Sandbank, M, 1994)
" Multivariate analyses identified the following factors to be associated with fracturing: years taking prednisone, previous diagnosis of osteoporosis, disability, age, lack of physical activity, female sex, disease duration, impaired grip strength, and low body mass."	3.68	Fractures in rheumatoid arthritis: an evaluation of associated risk factors. ( Bloch, DA; Fries, JF; Michel, BA; Wolfe, F, 1993)
" We describe six patients, all under 45 yrs of age, with chronic long-standing sarcoidosis, in whom long-term prednisone therapy resulted in 15 +/- 7% bone loss, as evaluated by quantitative computed tomography."	3.68	Reversibility of exogenous corticosteroid-induced bone loss. ( Montemurro, L; Rizzato, G, 1993)
"The effect of long-acting medroxyprogesterone acetate (MPA) on the trabecular bone density in patients with glucocorticoid-induced osteoporosis (GCO) was evaluated."	3.68	Effective therapy of glucocorticoid-induced osteoporosis with medroxyprogesterone acetate. ( Grecu, EO; Simmons, R; Weinshelbaum, A, 1990)
" Group 1 (67 patients) had steroid dependent asthma (mean daily dose of prednisone 11."	3.68	Vertebral fractures in steroid dependent asthma and involutional osteoporosis: a comparative study. ( Del Rio, L; Guañabens, N; Luengo, M; Montserrat, JM; Picado, C; Setoain, J, 1991)
"The basal and calcium-stimulated calcitonin response was measured in 10 patients with giant cell arteritis before and 1, 3 and 6 wk after the start of daily treatment with 60 mg of prednisone."	3.68	Change of serum calcitonin in patients receiving glucocorticoids: an acute phase study. ( Hackeng, WH; Mulder, H; Siersema-Smallegange, M; vd Lely, AJ, 1990)
"Long-acting medroxyprogesterone acetate (MPA) effect on some important parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis (GCO) was evaluated."	3.68	Effects of medroxyprogesterone acetate on some parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis. ( Baylink, DJ; Grecu, EO; Haloran, BP; Simmons, R; Spencer, ME, 1991)
"Prednisone-induced osteoporosis is very frequent in the long-term treatment of sarcoidosis (sarcoidosis 4:45-48, 1987)."	3.67	Bone protection with salmon calcitonin (sCT) in the long-term steroid therapy of chronic sarcoidosis. ( Montemurro, L; Rizzato, G; Schiraldi, G; Sisti, S; Tosi, G; Zanni, D, 1988)
"The bone mineral content (BMC) in both forearms (highly correlated to total body calcium) was measured by photon absorptiometry in a representative sample of rheumatoid arthritis outpatients comprising 129 patients treated with either gold salts (n = 29), penicillamine (n = 61), prednisone (n = 24), or other anti-RA drugs (n = 15)."	3.67	Prevalence of decreased bone mass in rheumatoid arthritis. Relation to anti-inflammatory treatment. ( Als, OS; Christiansen, C; Hellesen, C, 1984)
"Synthetic 1alpha-hydroxycholecalciferol, a potent vitamin D analogue, was given daily together with calcium to seven patients with senile osteoporosis and to three patients with prednisone-induced bone loss."	3.65	Effect of 1alpha-hydroxycholecalciferol in senile osteoporosis and in bone loss following prednisone treatment. ( Andersen, RB; Friis, TH; Hjorth, L; Kjaer, I; Lund, B; Reimann, I; Sorensen, OH, 1977)
"Patients with Cushing's syndrome have a high prevalence of osteoporotic fractures."	2.73	Cushing's syndrome and bone mineral density: lowest Z scores in young patients. ( den Heijer, M; Hermus, AR; Oyen, WJ; van der Eerden, AW, 2007)
"Osteoporosis is a common complication of long-term glucocorticoid therapy for which there is no well-proved preventive or restorative treatment."	2.69	Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. ( Brown, JP; Czachur, M; Daifotis, AG; Delmas, PD; Emkey, R; Goemaere, S; Hawkins, F; Liberman, UA; Malice, MP; Saag, KG; Schnitzer, TJ; Thamsborg, G, 1998)
"Osteoporosis has been recognized as an important side effect of long-term and of pulsed steroid application after heart transplantation."	2.69	Progression of steroid-associated osteoporosis after heart transplantation. ( Abraham, C; Cremer, J; Demertzis, S; Graeter, T; Haverich, A; Nischelsky, J; Strüber, M; Wagenbreth, I, 1999)
"Osteoporosis is a recognized complication of corticosteroid therapy."	2.68	Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis. ( Adachi, JD; Bensen, WG; Brown, J; Chines, AA; Hanley, D; Hodsman, A; Josse, R; Kendler, DL; Lentle, B; Olszynski, W; Ste-Marie, LG; Tenenhouse, A, 1997)
"Osteoporosis is a serious side effect of systemic treatment with steroids."	2.67	Does alternate-day cloprednol therapy prevent bone loss? A longitudinal double-blind, controlled clinical study. ( Medici, TC; Rüegsegger, P, 1990)
"Prevention or treatment of osteoporosis should be considered in all patients who received a daily dose of at least 7."	2.49	[Corticosteroid-induced osteoporosis]. ( Briot, K; Roux, C, 2013)
"GC stimulates osteoclast-mediated bone resorption and reduces osteoblast-mediated bone formation, which results in increased overall net bone resorption."	2.47	Adverse effects of corticosteroids on bone metabolism: a review. ( Mitra, R, 2011)
"Osteopenia or osteoporosis is common in patients with inflammatory bowel disease."	2.40	Prevention and treatment of osteoporosis in patients with inflammatory bowel disease. ( Sninsky, CA; Valentine, JF, 1999)
" It is clear that new dosing arrangements need to be created and studied."	2.39	Corticosteroids in the treatment of rheumatologic diseases. ( Weisman, MH, 1995)
" We evaluated adverse side effects (ASEs) of corticosteroid treatment in patients with gMG."	1.62	Adverse Side Effects Associated with Corticosteroid Therapy: A Study in 39 Patients with Generalized Myasthenia Gravis. ( Govindarajan, R; Johnson, S; Katyal, N; Narula, N, 2021)
" Although daily glucocorticoid therapy has been shown to extend ambulatory function in DMD, less frequent dosing is often used because of side effect concerns."	1.46	Long-Term Outcome of Interdisciplinary Management of Patients with Duchenne Muscular Dystrophy Receiving Daily Glucocorticoid Treatment. ( Jefferies, JL; McMahon, MA; Rutter, MM; Rybalsky, I; Sawnani, H; Shellenbarger, KC; Tian, C; Wong, BL, 2017)
"Relapses were defined as reappearance of disease-related symptoms requiring treatment adjustment."	1.40	Relapses in patients with giant cell arteritis: prevalence, characteristics, and associated clinical findings in a longitudinally followed cohort of 106 patients. ( Alba, MA; Butjosa, M; Cid, MC; Corbera-Bellalta, M; Espígol-Frigolé, G; García-Martínez, A; Hernández-Rodríguez, J; Planas-Rigol, E; Prieto-González, S; Tavera-Bahillo, I, 2014)
"Glucocorticoid (GC) induced osteoporosis (GIO) is caused by the long-term use of GC for treatment of autoimmune and inflammatory diseases."	1.38	Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis. ( Chen, Y; Cui, L; Huang, L; Jee, WS; Li, P; Li, T; Liu, Y; Tian, X; Wu, T; Xu, B; Zhou, L, 2012)
" The dosage of glucocorticoids was higher among women than men (11."	1.36	Glucocorticoid-related osteoporotic fractures. ( Al-Elq, AH; Al-Omran, AS; Al-Osail, AM; Azzam, Q; Sadat-Ali, M, 2010)
"We identified 1909 COPD patients admitted with a main diagnosis of COPD."	1.36	Screening, prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease - a population-based database study. ( Brixen, K; Hallas, J; Madsen, H, 2010)
"Prednisone was started during the ambulant phase at age 3."	1.35	Prednisone 10 days on/10 days off in patients with Duchenne muscular dystrophy. ( de Groot, IJ; Overweg-Plandsoen, WC; Straathof, CS; van den Burg, GJ; van der Kooi, AJ; Verschuuren, JJ, 2009)
" We also examined how glucocorticoid dosage affected osteoporosis management in adjusted models."	1.33	Osteoporosis management in patients with rheumatoid arthritis: Evidence for improvement. ( Bukowski, JF; Cabral, D; Coblyn, JS; Katz, JN; Patrick, AR; Solomon, DH, 2006)
"Osteoporosis was demonstrated in 35."	1.33	Correlation of different bone markers with bone density in patients with rheumatic diseases on glucocorticoid therapy. ( Bohl, N; Burmester, GR; Buttgereit, F; Loddenkemper, K; Perka, C, 2006)
"Zoledronic acid is a new intravenous bisphosphonate that has been approved by the US FDA for use with hypercalcemia of malignancies and might be an effective treatment for postmenopausal osteoporosis."	1.32	The effect of intravenous zoledronic acid on glucocorticoid-induced multiple vertebral fractures in juvenile systemic lupus erythematosus. ( Borges, CT; Jorgetti, V; Pereira, RM; Souza, SC, 2004)
"Relapses were treated with 60 mg/m2/d until remission for 3 days, followed by 40 mg on alternate days for 4 weeks and tapered by 10 mg/m2/wk."	1.32	Are children with idiopathic nephrotic syndrome at risk for metabolic bone disease? ( Godbole, M; Gulati, K; Gulati, S; Singh, U; Srivastava, A, 2003)
" The mean daily dosage of prednisone (or its equivalent) was 8."	1.31	Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: rates and predictors of care in an academic rheumatology practice. ( Coblyn, J; Jacobs, JP; Katz, JN; La Tourette, AM; Solomon, DH, 2002)
" They had been receiving oral prednisone treatment for a median of 30 months (range 6-74); mean daily dosage during the six-month study period was 12."	1.31	Management of glucocorticoid-induced osteoporosis in male veterans. ( Binkley, NC; Carnes, ML; Elliott, ME; Farrah, RM; Gudmundsson, A, 2000)
"Osteoporosis is a major complication of long-term corticosteroid administration, but the magnitude of the effect in patients with chronic obstructive pulmonary disease (COPD) is not well defined."	1.30	Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease. ( Bender, E; Ensrud, KE; Genant, HK; Griffith, JM; McEvoy, CE; Niewoehner, DE; Yu, W, 1998)
"Iatrogenic osteoporosis is a very common secondary osteoporosis is found in patients treated with large dosage of glucocorticosteroid of long duration."	1.29	[Iatrogenic osteoporsis: six case reports]. ( Wang, JZ; Zheng, LM, 1994)
"The experimental result has shown that the water extract of Herba Epimedii (Epimedium sagittalum) works very well in preventing and curing the side effects induced by long-term use of glucocorticoids in rats, especially in antagonizing adrenocortical atrophy and osteoporosis."	1.29	[Experimental study on antagonizing action of herba Epimedii on side effects induced by glucocorticoids]. ( Chen, Z; Cui, L; Huang, L; Li, Q; Liao, J; Wu, T; Zhang, Z, 1996)
" Vertebral fractures (VF) were found in four men and were associated with higher prednisone dosage (P < 0."	1.29	Long-term bone loss in kidney transplant recipients: a cross-sectional and longitudinal study. ( Bonnardeaux, A; Cardinal, J; Gagné, M; Ouimet, D; Pichette, V; Prudhomme, L, 1996)
"Prednisone acetate was given to the group B twice per weeks, Zhuanggu Shengbao (ZGSB) was added to the group C besides prednisone, the group A was control."	1.29	[Experimental study on zhuanggu shengbao in preventing hormone-induced osteoporosis of rats]. ( Li, Q; Liao, J; Wu, T, 1996)
"However, many patients with end-stage pulmonary disease have multiple risk factors for osteoporosis, and several studies have suggested that osteoporosis before transplantation may increase the risk of fracture after transplantation."	1.29	Osteoporosis in lung transplantation candidates with end-stage pulmonary disease. ( Addesso, V; Donovan, D; Jorgesen, B; McGregor, C; Papadopoulos, A; Schulman, L; Shane, E; Silverberg, SJ; Staron, RB, 1996)
"In comparison with control rats, the bone resorption was enhanced and bone formation decreased."	1.29	[Effect of total coumarins from dried fruits of Cnidium monnieri on glucocorticoid-induced osteoporosis in rats]. ( Huang, LF; Li, QN; Wu, T; Xie, H, 1994)
"To assess the impact of primary biliary cirrhosis on bone mass in general and the relative importance of the stage of the liver disease and of treatment with glucocorticoids for the possible development of osteoporosis, bone mineral mass was measured by single and dual photon absorptiometry in 55 unselected female patients with longstanding primary biliary cirrhosis."	1.28	Bone mass in women with primary biliary cirrhosis: the relation with histological stage and use of glucocorticoids. ( Beukers, R; Birkenhäger, JC; Kooij, PP; Pols, HA; Schalm, SW; Van Berkum, FN, 1990)
"The long-term use of glucocorticoid drugs frequently results in the development of osteoporosis."	1.27	Calcium supplements in the prevention of steroid-induced osteoporosis. ( Ibbertson, HK; Reid, IR, 1986)

Research

Studies (249)

Authors

Clinical Trials (10)

Trial Overview

Trial Outcomes

Change From Baseline at 18 Month Endpoint in Lumbar Spine Bone Mineral Density (BMD)

Timeframe	Studies, this research(%)	All Research%
pre-1990	82 (32.93)	18.7374
1990's	68 (27.31)	18.2507
2000's	56 (22.49)	29.6817
2010's	36 (14.46)	24.3611
2020's	7 (2.81)	2.80

Authors	Studies
Wang, C	1
Cui, W	1
Zhao, M	1
Yang, J	1
Peng, S	1
Johnson, S	1
Katyal, N	1
Narula, N	1
Govindarajan, R	1
Lefeuvre, L	1
Caruso, A	1
Biver, E	1
Fayolle, D	1
Adami, G	1
Fassio, A	1
Rossini, M	3
Benini, C	1
Pistillo, F	1
Viapiana, O	2
Bertelle, D	1
Gatti, D	3
Sapkota, S	1
Baig, S	1
Hess, T	1
O'Connell, AM	1
Menk, J	1
Shyne, M	1
Fazeli, P	1
Ensrud, K	1
Shmagel, A	1
Ruiz-Irastorza, G	1
Ugarte, A	1
Ruiz-Arruza, I	1
Khamashta, M	1
Hayat, S	1
Magrey, MN	1
Chavatza, K	1
Kostopoulou, M	1
Nikolopoulos, D	1
Gioti, O	1
Togia, K	1
Andreoli, L	1
Aringer, M	1
Boletis, J	1
Doria, A	1
Houssiau, FA	1
Jayne, D	1
Mosca, M	1
Svenungsson, E	1
Tincani, A	1
Bertsias, G	1
Fanouriakis, A	1
Boumpas, DT	1
Yang, YJ	1
Zhu, Z	1
Wang, DT	1
Zhang, XL	1
Liu, YY	1
Lai, WX	1
Mo, YL	1
Li, J	1
Liang, YL	1
Hu, ZQ	1
Yu, YJ	1
Cui, L	4
Wang, H	1
Feng, T	1
Guo, D	1
Zhang, M	1
Chen, L	1
Zhou, Y	1
Giollo, A	1
Bettili, F	1
Ghellere, F	1
Fracassi, E	1
Idolazzi, L	1
Buckley, L	1
Humphrey, MB	1
Koller, G	1
Katz, S	1
Charrois, TL	1
Ye, C	1
Mahmood, K	1
Koubar, S	1
Shofer, SL	1
Ninan, NA	1
Wahidi, MM	1
Majumdar, SR	1
Lix, LM	1
Morin, SN	1
Yogendran, M	1
Metge, CJ	1
Leslie, WD	1
Saag, KG	4
Curtis, J	1
Warriner, A	1
Dominguez, AR	1
Goldman, SE	1
Velázquez Benito, A	1
Bellosta Diago, E	1
Santos Lasaosa, S	1
Pascual Millán, LF	1
Lems, WF	2
Lin, S	1
Huang, J	1
Zheng, L	1
Liu, Y	3
Liu, G	1
Li, N	1
Wang, K	1
Zou, L	1
Wu, T	9
Qin, L	1
Li, G	1
Alba, MA	1
García-Martínez, A	1
Prieto-González, S	1
Tavera-Bahillo, I	1
Corbera-Bellalta, M	1
Planas-Rigol, E	1
Espígol-Frigolé, G	1
Butjosa, M	1
Hernández-Rodríguez, J	1
Cid, MC	1
Leib, ES	3
Winzenrieth, R	1
Agnusdei, D	1
Hans, D	1
Kohlmeier, LA	1
Krohn, KD	1
MacLaughlin, EJ	1
Alam, J	1
Simonelli, C	1
Taylor, KA	1
Marcus, R	1
Muruganandam, M	1
Sandhu, H	1
Faraj, W	1
El Nounou, G	1
Abou Al Naaj, A	1
Nakhoul, N	1
Haydar, A	1
Khalife, M	1
Tsang-A-Sjoe, MW	1
Bultink, IE	1
Heslinga, M	1
Voskuyl, AE	1
Wong, BL	1
Rybalsky, I	1
Shellenbarger, KC	1
Tian, C	1
McMahon, MA	1
Rutter, MM	1
Sawnani, H	1
Jefferies, JL	1
Masala, S	1
Anselmetti, GC	1
Marcia, S	1
Massari, F	1
Manca, A	1
Simonetti, G	1
Yokote, Y	1
Kimura, E	1
Kimura, M	1
Kozono, Y	1
Straathof, CS	1
Overweg-Plandsoen, WC	1
van den Burg, GJ	1
van der Kooi, AJ	1
Verschuuren, JJ	1
de Groot, IJ	1
Coulson, KA	1
Reed, G	1
Gilliam, BE	1
Kremer, JM	1
Pepmueller, PH	1
Zou, X	1
Li, Q	5
Shi, C	1
Ali Ou Alla, S	1
Allali, F	1
Hajjaj-Hassouni, N	1
Pepene, CE	1
Seck, T	1
Diel, I	1
Minne, HW	1
Ziegler, R	1
Pfeilschifter, J	1
Rolnick, SJ	1
Jackson, JM	1
Amundson, JH	1
Madsen, H	1
Brixen, K	1
Hallas, J	1
Husein-Elahmed, H	1
Aneiros-Fernandez, J	1
Arias-Santiago, S	1
Aneiros-Cachaza, J	1
Naranjo-Sintes, R	1
Schmajuk, G	1
Yelin, E	1
Chakravarty, E	1
Nelson, LM	1
Panopolis, P	1
Yazdany, J	1
Sbrocchi, AM	1
Rauch, F	1
Matzinger, M	1
Feber, J	1
Ward, LM	1
Al-Osail, AM	1
Sadat-Ali, M	1
Al-Elq, AH	1
Al-Omran, AS	1
Azzam, Q	1
Guillén, CA	1
Zea, AC	1
Mitra, R	1
Weinstein, RS	2
Di Munno, O	1
Delle Sedie, A	1
Roux, C	2
Reid, DM	3
Devogelaer, JP	3
Saag, K	1
Lau, CS	1
Reginster, JY	2
Papanastasiou, P	2
Bucci-Rechtweg, C	2
Su, G	2
Sambrook, PN	1
Li, T	1
Zhou, L	1
Li, P	1
Xu, B	1
Huang, L	4
Chen, Y	2
Tian, X	1
Jee, WS	1
McKeown, E	1
Bykerk, VP	1
De Leon, F	1
Bonner, A	1
Thorne, C	1
Hitchon, CA	1
Boire, G	1
Haraoui, B	1
Ferland, DS	1
Keystone, EC	1
Pope, JE	1
van der Goes, MC	1
Jacobs, JW	3
Jurgens, MS	1
Bakker, MF	1
van der Veen, MJ	1
van der Werf, JH	1
Welsing, PM	1
Bijlsma, JW	3
Briot, K	1
Sambrook, P	3
Goemaere, S	3
Ish-Shalom, S	1
Collette, J	1
Hu, B	3
Li, C	1
Yen, D	1
Hedden, D	1
Solomon, DH	2
Katz, JN	2
Jacobs, JP	1
La Tourette, AM	1
Coblyn, J	1
Chevalet, P	1
Masseau-Imbert, A	1
Durand-Fix, MH	1
Agard, C	2
Brisseau, JM	1
Rodat, O	1
Barrier, JH	2
Liao, JM	2
Li, QN	3
Huang, LF	3
Li, ZH	1
Zhao, WD	1
Zhang, MC	1
Zhong, SZ	1
Emkey, R	2
Delmas, PD	3
Liberman, UA	2
Poubelle, PE	1
Daifotis, AG	2
Verbruggen, N	1
Lombardi, A	1
Czachur, M	2
Beglinger, Ch	1
Jódar, E	1
Valdepeñas, MP	1
Martinez, G	1
Jara, A	1
Hawkins, F	2
Gulati, S	1
Godbole, M	1
Singh, U	1
Gulati, K	1
Srivastava, A	1
RANKIN, TJ	1
MARKHAM, S	1
RUTSCHMANN, JP	1
DELACHAUX, A	1
HEATHER, AJ	1
LUND, H	1
CHARPIN, J	1
PAYAN, H	1
LUCCIONI, R	1
LIEUTAUD, R	1
OHRESSER, P	1
NICOLINO, J	1
MYKHAMEDZIANOVA, GS	1
RICH, C	1
ENSINCK, J	1
IVANOVICH, P	1
MUSSHOFF, K	1
MUELLER, W	1
LITWIN, SD	1
LISTER, J	1
ROTSTEIN, J	1
ROTHERMICH, NO	1
FISHER, DA	1
PANOS, TC	1
MELBY, JC	1
KENDALL, PH	2
Frediani, B	1
Falsetti, P	1
Baldi, F	1
Acciai, C	1
Filippou, G	1
Marcolongo, R	1
Boyanov, M	1
Robeva, R	1
Popivanov, P	1
Adler, RA	1
Hochberg, MC	2
Huang, K	1
Lang, F	1
Huang, Y	1
Huang, H	2
Zhou, C	1
Zhang, W	1
García Camín, RM	1
Cabezas, A	1
Calero, F	1
Ballarín, JA	1
Habib, GS	1
Haj, S	1
Tanaka, Y	1
Souza, SC	1
Borges, CT	1
Jorgetti, V	1
Pereira, RM	1
Liao, J	3
Li, Z	1
Zhong, S	1
Ortego-Centeno, N	1
Muñoz-Torres, M	1
Callejas-Rubio, JL	1
Riera-Montes, M	1
Loddenkemper, K	1
Bohl, N	1
Perka, C	1
Burmester, GR	1
Buttgereit, F	1
Feldstein, AC	1
Elmer, PJ	1
Nichols, GA	1
Herson, M	1
Kutilek, S	1
Bayer, M	1
Dolezalova, P	1
Nemcova, D	1
Gehlbach, SH	1
Curtis, JR	1
Youket, TE	1
Worley, K	1
Lange, JL	1
Cabral, D	1
Patrick, AR	1
Bukowski, JF	1
Coblyn, JS	1
Shah, SK	1
Gecys, GT	1
Guzman-Clark, JR	1
Fang, MA	1
Sehl, ME	1
Traylor, L	1
Hahn, TJ	1
van der Eerden, AW	1
den Heijer, M	1
Oyen, WJ	1
Hermus, AR	1
Papierska, L	1
Rabijewski, M	1
Rossi, CM	1
Di Comite, G	1
Cohran, VC	1
Griffiths, M	1
Heubi, JE	1
Wijbrandts, CA	1
Klaasen, R	1
Dijkgraaf, MG	1
Gerlag, DM	1
van Eck-Smit, BL	1
Tak, PP	1
Duncan, H	2
Lindholm, B	1
Gasparini, M	1
Zizic, TM	1
Abbrederis, K	1
Gattringer, C	1
König, P	1
Gastl, G	1
Lo Cascio, V	2
Bonucci, E	2
Imbimbo, B	1
Ballanti, P	2
Tartarotti, D	1
Galvanini, G	1
Fuccella, L	1
Adami, S	3
Als, OS	1
Christiansen, C	1
Hellesen, C	1
Frey, FJ	1
Rubinow, A	1
Brandt, KD	1
Cohen, AS	1
Sack, B	1
Webb, DR	1
Baylink, DJ	2
Greenwald, RA	1
Lane, NE	3
Mroczkowski, PJ	1
Pons, F	2
Peris, P	2
Guañabens, N	4
Font, J	1
Huguet, M	1
Espinosa, G	1
Ingelmo, M	1
Muñoz-Gomez, J	2
Setoain, J	3
Weisman, MH	1
Boot, AM	1
Nauta, J	1
Hokken-Koelega, AC	1
Pols, HA	2
de Ridder, MA	1
de Muinck Keizer-Schrama, SM	1
Hahn, BH	1
Mazzaferri, EL	1
Struys, A	1
Snelder, AA	1
Mulder, H	2
Zheng, LM	1
Wang, JZ	1
Xie, H	1
Carlson, K	1
Aström, G	1
Nyman, R	1
Ahlström, H	1
Simonsson, B	1
Grotz, W	1
Mundinger, A	1
Gugel, B	1
Exner, V	1
Reichelt, A	1
Schollmeyer, P	1
Worth, H	1
Stammen, D	1
Keck, E	1
Romano, TJ	1
Lapidoth, M	1
David, M	1
Ben-Amitai, D	1
Katzenelson, V	1
Lustig, S	1
Sandbank, M	1
Pirofsky, JG	1
Huang, CT	1
Waites, KB	1
Michel, BA	2
Bloch, DA	2
Wolfe, F	1
Fries, JF	2
Rizzato, G	6
Montemurro, L	4
Shane, E	2
Rivas, MC	1
Silverberg, SJ	2
Kim, TS	1
Staron, RB	2

Trial	Phase	Enrollment	Study Type	Start Date	Status
Biomarkers in Giant Cells Arteritis[NCT02844023]		100 participants (Actual)	Interventional	2015-01-31	Terminated (stopped due to recruitment failure)
Comparison of the Effects of Teriparatide With Those of Alendronate Sodium on Lumbar Spine Bone Mineral Density in Glucocorticoid-Induced Osteoporosis[NCT00051558]	Phase 3	428 participants (Actual)	Interventional	2002-11-30	Completed
A Prospective Baseline Assessment of the Risk of Osteoporosis in Patients With Chronic Obstructive Lung Disease and Outcomes After 2 Years; a Pilot Study[NCT01161680]		30 participants (Actual)	Observational	2010-07-31	Completed
Efficacy and Safety of Zoledronic Acid in the Prevention and Treatment of Corticosteroid Induced Osteoporosis[NCT00100620]	Phase 3	802 participants	Interventional	2004-06-30	Completed
Prognostic Factors of Efficacy in Corticoid and Anesthetic Joint Infiltration for the Treatment of Patients With Low Back Pain Secondary to Zygapophyseal Osteoarthritis: a Prospective Cohort Study[NCT03304730]		147 participants (Anticipated)	Observational	2017-09-01	Recruiting
Low-level Mechanical Vibration, Bone Density, Bone Resorption and Muscular Strength in Ambulant Children Affected by Duchenne Muscular Dystrophy[NCT05281120]		20 participants (Actual)	Interventional	2006-11-30	Completed
Teriparatide for Joint Erosions in Rheumatoid Arthritis: The TERA Trial[NCT01400516]	Phase 4	26 participants (Actual)	Interventional	2011-08-31	Completed
Prevention of Glucocorticoid-Induced Osteoporosis in Patients With Rheumatic Diseases. The STOP-Study: a Randomized Placebo Controlled Trial With Alendronate Versus Alfacalcidol.[NCT00138983]	Phase 3	200 participants	Interventional	2000-05-31	Completed
Bisphosphonates for Prevention of Post-Denosumab Bone Loss in Premenopausal Women With Idiopathic Osteoporosis[NCT03396315]	Phase 2	27 participants (Actual)	Interventional	2018-01-29	Active, not recruiting
Comparison of the Efficacy and Safety of Two Different Starting Dosages of Prednisolone in Early Active Rheumatoid Arthritis: a Randomized, Placebo Controlled Trial[NCT02000336]	Phase 3	395 participants (Actual)	Interventional	2014-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

change from baseline at endpoint in bone mineral density of the lumbar spine as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 18 month endpoint

Change From Baseline at 18 Month Endpoint in Lumbar Spine Bone Mineral Density (BMD), Female Subset

Intervention	grams per square centimeters (Least Squares Mean)
Teriparatide	0.059
Alendronate	0.028

change from baseline at endpoint in bone mineral density of the lumbar spine as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 18 month endpoint

Any Fracture, Nonvertebral Fractures, Vertebral Fractures, Clinical Vertebral Fractures, and Severity Fractures

Intervention	grams per square centimeters (Least Squares Mean)
Teriparatide	0.056
Alendronate	0.023

Clinical vertebral fracture was defined as a radiographically confirmed fracture that was associated with symptoms such as back pain. (NCT00051558)
Timeframe: 36 months

Change From Baseline in Femoral Neck Bone Mineral Density (BMD), Women and Men Combined

Intervention	participants (Number)
	Any Fracture	Nonvertebral Fracture	Vertebral Fracture	Clinical Vertebral Fracture	Nonvertebral Fragility Fracture	Severity-Radiographic Vertebral Fracture: Mild	Severity-Radiographic Vertebral Fracture: Moderate	Severity-Radiographic Vertebral Fracture: Severe
Alendronate	27	15	13	4	5	7	2	4
Teriparatide	19	16	3	0	9	1	2	0

change from baseline in bone mineral density of the femoral neck as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 18, 24, 36 months, and 18 and 36 month endpoints

Change From Baseline in Lumbar Spine Bone Mineral Density (BMD), Women and Men Combined

Intervention	grams per square centimeters (Least Squares Mean)
	Change, baseline to 36 month endpoint(N=185,N=177)	Change from baseline at 36 months(N=120,N=113)	Change from baseline at 24 months(N=135,N=131)	Change, baseline to 18 month endpoint(N=185,N=176)	Change from baseline at 18 months (N=156,N=145)
Alendronate	0.017	0.021	0.015	0.014	0.017
Teriparatide	0.033	0.041	0.030	0.024	0.028

change from baseline in bone mineral density of the lumbar spine as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 24 and 36 months and Endpoint at 36 months

Change From Baseline in Total Hip Bone Mineral Density (BMD), Women and Men Combined

Intervention	grams per square centimeters (Least Squares Mean)
	Change, baseline to 36 month endpoint(N=198,N=195)	Change from baseline at 36 months (N=123, N=112)	Change from baseline at 24 months (N=136, N=131)
Alendronate	0.034	0.044	0.043
Teriparatide	0.073	0.090	0.081

change from baseline in bone mineral density of the total hip as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 18, 24, 36 months, and 18 and 36 month endpoints

Time Course of Change From Baseline in Bone Turnover Markers in Subset of Patients - Bone-Specific Alkaline Phosphatase

Time Course of Change From Baseline in Bone Turnover Markers in Subset of Patients - Osteocalcin

Time Course of Change From Baseline in Bone Turnover Markers in Subset of Patients - Serum C-terminal Propeptide of Type 1 Procollagen

Time Course of Change From Baseline in Bone Turnover Markers in Subset of Patients - Serum N-terminal Propeptide of Type 1 Procollagen

Time Course of Change From Baseline in Bone Turnover Markers in Subset of Patients - Serum Type 1 Collagen Degradation Fragments

Time Course of Change From Baseline in Femoral Neck Bone Mineral Density (BMD), Women and Men Combined

Intervention	grams per square centimeters (Least Squares Mean)
	Change, baseline to 36 month endpoint(N=185,N=177)	Change from baseline at 36 months(N=120,N=113)	Change from baseline at 24 months(N=135,N=131)	Change, baseline to 18 month endpoint(N=185,N=176)	Change from baseline at 18 months (N=156,N=144)
Alendronate	0.017	0.020	0.018	0.017	0.018
Teriparatide	0.032	0.037	0.034	0.026	0.027

Intervention	percent (Mean)
	Percent change from baseline at Month 1(N=65,N=78)	Percent change from baseline at Month 6(N=66,N=76)	Percent change from baseline at Month18(N=54,N=65)	Percent change from baseline at Month36(N=44,N=49)
Alendronate	0.5	-7.2	-4.1	20.6
Teriparatide	35.0	52.3	34.4	44.7

Intervention	percent (Mean)
	Percent change from baseline at Month1(N=94,N=100)	Percent change from baseline at Month 6(N=84,N=88)	Percent change from baseline at Month18(N=77,N=77)	Percent change from baseline at Month36(N=56,N=58)
Alendronate	-5.2	-33.6	-25.0	-19.6
Teriparatide	147.1	120.0	108.9	62.1

Intervention	percent (Mean)
	Percent change from baseline at Month 1(N=66,N=78)	Percent change from baseline at Month 6(N=67,N=76)	Percent change from baseline at Month18(N=55,N=65)	Percent change from baseline at Month36(N=45,N=49)
Alendronate	-8.8	-22.3	-21.3	-15.4
Teriparatide	48.2	10.5	5.1	-1.3

Intervention	percent (Mean)
	Percent change from baseline at Month 1(N=98,N=99)	Percent change from baseline at Month 6(N=86,N=85)	Percent change from baseline at Month18(N=77,N=76)	Percent change from baseline at Month36(N=59,N=57)
Alendronate	-14.8	-43.2	-35.8	-20.2
Teriparatide	107.0	130.8	86.3	61.7

Intervention	percent (Mean)
	Percent change from baseline at Month 1(N=70,N=79)	Percent change from baseline at Month 6(N=66,N=75)	Percent change from baseline at Month18(N=64,N=71)	Percent change from baseline at Month36(N=49,N=48)
Alendronate	-38.6	-42.4	-47.5	-16.2
Teriparatide	29.0	66.8	29.1	30.7

change from baseline in bone mineral density of the femoral neck as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 12, 18, 24, and 36 months

Time Course of Change From Baseline in Lumbar Spine Bone Mineral Density (BMD), Female Subset

Intervention	grams per square centimeters (Least Squares Mean)
	Change from baseline at Month 36 (N=120,N=113)	Change from baseline at Month 24 (N=135,N=131)	Change from baseline at Month 18 (N=156,N=145)	Change from baseline at Month 12 (N=167,N=158)
Alendronate	0.021	0.015	0.017	0.012
Teriparatide	0.041	0.030	0.028	0.026

change from baseline in bone mineral density of the lumbar spine as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 3, 6, 12, and 18 months

Time Course of Change From Baseline in Lumbar Spine Bone Mineral Density (BMD), Women and Men Combined

Intervention	grams per square centimeters (Least Squares Mean)
	Change from baseline at Month 18 (N=127,N=119)	Change from baseline at Month 12 (N=139,N=129)	Change from baseline at Month 6 (N=147,N=139)	Change from baseline at Month 3 (N=149,N=150)
Alendronate	0.027	0.024	0.015	0.012
Teriparatide	0.062	0.052	0.031	0.017

change from baseline in bone mineral density of the lumbar spine as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 3, 6, 12, 18, 24, 36 months

Time Course of Change From Baseline in Total Hip Bone Mineral Density (BMD), Women and Men Combined

Intervention	grams per square centimeters (Least Squares Mean)
	Change from baseline at Month 36 (N=123,N=112)	Change from baseline at Month 24 (N=136,N=131)	Change from baseline at Month 18 (N=156,N=148)	Change from baseline at Month 12 (N=170,N=159)	Change from baseline at Month 6 (N=178,N=173)	Change from baseline at Month 3 (N=183,N=184)
Alendronate	0.044	0.043	0.031	0.028	0.018	0.012
Teriparatide	0.090	0.081	0.066	0.054	0.034	0.019

change from baseline in bone mineral density of the total hip as assessed by dual energy X-ray absorptiometry (DXA) (NCT00051558)
Timeframe: 12, 18, 24, and 36 months

Change From Baseline in Bone Mineral Density (BMD) Measured by Dual-Energy X-ray Absorptiometry (DXA) and Instant Vertebral Assessment (IVA) Scan

Intervention	grams per square centimeters (Least Squares Mean)
	Change from baseline at 36 Months (N=120, N=113)	Change from baseline at 24 Months (N=135, N=131)	Change from baseline at 18 Months (N=156, N=145)	Change from baseline at 12 Months (N=167, N=158)
Alendronate	0.020	0.018	0.018	0.014
Teriparatide	0.037	0.034	0.027	0.022

BMD was measured at the lumbosacral spine antero-posterior and at the femoral neck using a densitometer. A positive change from Baseline (increased bone density) indicates improvement. (NCT01400516)
Timeframe: Baseline and Month 12

Change From Baseline in Disease Activity Score 28 Joint Count C-Reactive Protein (DAS-28 CRP)

Intervention	grams/centimeters squared (g/cm^2) (Mean)
	Spine, Baseline	Spine, Change from Baseline at Month12	Femoral neck, Baseline	Femoral neck, Change from Baseline at Month 12
Control Arm	0.93	-0.002	0.73	-0.03
Teriparatide	0.91	0.06	0.68	0.03

The DAS28 score is a measure of the patient's disease activity calculated using the tender joint count (TJC) [28 joints], swollen joint count (SJC) [28 joints], patient's global assessment of disease activity [visual analog scale: 0=no disease activity to 100=maximum disease activity] and C-Reactive Protein (CRP) for a total possible score of 2 to 10. Higher values indicate higher disease activity. A negative change from baseline indicates improvement. (NCT01400516)
Timeframe: Baseline and Month 12

Change From Baseline in Joint Erosion Volume Measured by 3-Dimensional Computed Tomography (3D CT) Scan

Intervention	score on a scale (Mean)
	Baseline	Change from Baseline at Month 12
Control Arm	2.73	-0.50
Teriparatide	2.66	0.42

Both hands were scanned using a CT scanner. A semi-automated software tool was used to segment the erosion margins in 3D. A board certified radiologist identified the individual erosions in six sub-regions: radius, ulna, proximal carpals, distal carpals, metacarpophalangeal (MCP) joints and proximal interphalangeal (PIP) joints. The average total in a single hand/wrist was calculated. A negative change from Baseline(less joint erosions) indicates improvement. (NCT01400516)
Timeframe: Baseline and Month 12

Article	Year
Seventy years after Hench's Nobel prize: revisiting the use of glucocorticoids in systemic lupus erythematosus. Lupus, 2020, Volume: 29, Issue:10 Topics: Administration, Oral; Disease Progression; Dose-Response Relationship, Drug; Drug Tapering; Female;	2020
Glucocorticoid-induced osteoporosis: Insights for the clinician. Cleveland Clinic journal of medicine, 2020, 06-30, Volume: 87, Issue:7 Topics: Adult; Bone Density; Cancellous Bone; Drug Administration Schedule; Female; Glucocorticoids; Humans;	2020
Glucocorticoid-Induced Osteoporosis. The New England journal of medicine, 2018, Dec-27, Volume: 379, Issue:26 Topics: Aged; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fractures, Bone; Gluco	2018
Adverse effects of corticosteroids on bone metabolism: a review. PM & R : the journal of injury, function, and rehabilitation, 2011, Volume: 3, Issue:5 Topics: Bone and Bones; Bone Resorption; Fractures, Bone; Glucocorticoids; Humans; Osteoblasts; Osteoclasts;	2011
Clinical practice. Glucocorticoid-induced bone disease. The New England journal of medicine, 2011, Jul-07, Volume: 365, Issue:1 Topics: Asthma; Bone Density; Bone Diseases; Calcium; Diphosphonates; Female; Fractures, Bone; Glucocorticoi	2011
[Prevention and treatment of glucocorticoid-induced osteoporosis in International and Italian scenarios]. Reumatismo, 2011, Volume: 63, Issue:2 Topics: Adult; Aged; Algorithms; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fra	2011
[Corticosteroid-induced osteoporosis]. La Revue de medecine interne, 2013, Volume: 34, Issue:5 Topics: Adrenal Cortex Hormones; Bone Density Conservation Agents; Diphosphonates; Fractures, Bone; Glucocor	2013
[Treatment of Crohn's disease]. Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:3 Topics: Acute Disease; Adjuvants, Immunologic; Adrenal Cortex Hormones; Algorithms; Aminosalicylic Acids; An	2003
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[Glucocorticoid-induced osteoporosis]. Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8 Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Calcium; Diphosphonates; Female; Fractu	2007
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Systemic lupus erythematosus X: corticosteroid therapy and its complications. Maryland state medical journal, 1984, Volume: 33, Issue:5 Topics: Anemia, Hemolytic; Central Nervous System Diseases; Cushing Syndrome; Humans; Kidney Diseases; Lupus	1984
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Trabecular Bone Score in Patients With Chronic Glucocorticoid Therapy-Induced Osteoporosis Treated With Alendronate or Teriparatide. Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:9 Topics: Alendronate; Bone Density Conservation Agents; Cancellous Bone; Chronic Disease; Double-Blind Method	2016
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Post hoc analysis of a single IV infusion of zoledronic acid versus daily oral risedronate on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012, Volume: 23, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bone Density; Bone De	2012
Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:4 Topics: Absorptiometry, Photon; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone	2013
Effect on bone turnover markers of once-yearly intravenous infusion of zoledronic acid versus daily oral risedronate in patients treated with glucocorticoids. Rheumatology (Oxford, England), 2013, Volume: 52, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents;	2013
Changes in bone mineral density following discontinuation or continuation of alendronate therapy in glucocorticoid-treated patients: a retrospective, observational study. Arthritis and rheumatism, 2003, Volume: 48, Issue:4 Topics: Adult; Aged; Alendronate; Bone Density; Dose-Response Relationship, Drug; Drug Administration Schedu	2003
Effects of 4-year treatment with once-weekly clodronate on prevention of corticosteroid-induced bone loss and fractures in patients with arthritis: evaluation with dual-energy X-ray absorptiometry and quantitative ultrasound. Bone, 2003, Volume: 33, Issue:4 Topics: Absorptiometry, Photon; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Arthrit	2003
Bone mineral density in patients with early rheumatoid arthritis treated with corticosteroids. Clinical rheumatology, 2005, Volume: 24, Issue:2 Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid;	2005
Etidronate and glucocorticoid induced osteoporosis. The Journal of rheumatology, 2005, Volume: 32, Issue:1 Topics: Asthma; Bone Density; Budesonide; Drug Therapy, Combination; Etidronic Acid; Glucocorticoids; Humans	2005
Cushing's syndrome and bone mineral density: lowest Z scores in young patients. The Netherlands journal of medicine, 2007, Volume: 65, Issue:4 Topics: Absorptiometry, Photon; Adult; Bone Density; Bone Resorption; Cushing Syndrome; Female; Femur Neck;	2007
Bone mineral density in rheumatoid arthritis patients 1 year after adalimumab therapy: arrest of bone loss. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:3 Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Ag	2009
Cyclical etidronate reverses bone loss of the spine and proximal femur in patients with established corticosteroid-induced osteoporosis. The American journal of medicine, 1995, Volume: 99, Issue:3 Topics: Absorptiometry, Photon; Aged; Alkaline Phosphatase; Bone Density; Calcium; Drug Administration Sched	1995
Missing impact of cyclosporine on osteoporosis in renal transplant recipients. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Absorptiometry, Photon; Age Factors; Analysis of Variance; Body Weight; Bone Density; Cyclosporine;	1994
Therapy of steroid-induced bone loss in adult asthmatics with calcium, vitamin D, and a diphosphonate. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:2 Topics: Adrenal Cortex Hormones; Asthma; Bone Density; Calcium; Drug Therapy, Combination; Etidronic Acid; F	1994
Corticosteroid-induced bone loss. The Journal of family practice, 1996, Volume: 42, Issue:4 Topics: Calcium; Etidronic Acid; Female; Femur; Follow-Up Studies; Glucocorticoids; Humans; Male; Middle Age	1996
Bone density loss during treatment of chronic GVHD. Bone marrow transplantation, 1996, Volume: 17, Issue:3 Topics: Absorptiometry, Photon; Adult; Bone Density; Bone Marrow Transplantation; Cyclosporine; Diet; Female	1996
Efficiency of preventive treatment of glucocorticoid-induced osteoporosis with 25-hydroxyvitamin D3 and calcium in kidney transplant patients. Transplantation proceedings, 1996, Volume: 28, Issue:6 Topics: Adolescent; Adult; Azathioprine; Bone Density; Calcitriol; Calcium; Calcium Carbonate; Cyclosporine;	1996
Salmon calcitonin nasal spray in the prevention of corticosteroid-induced osteoporosis. British journal of rheumatology, 1997, Volume: 36, Issue:2 Topics: Absorptiometry, Photon; Administration, Inhalation; Aged; Analgesics; Bone and Bones; Bone Density;	1997
Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis. The New England journal of medicine, 1997, Aug-07, Volume: 337, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Bone Density; Calcium Carbonate; Double-Blind Method; Drug Administr	1997
Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. The Journal of rheumatology, 1997, Volume: 24, Issue:8 Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Art	1997
Prevention of corticosteroid-induced osteoporosis with alendronate in sarcoid patients. Calcified tissue international, 1997, Volume: 61, Issue:5 Topics: Absorptiometry, Photon; Adult; Aged; Alendronate; Analysis of Variance; Anti-Inflammatory Agents; Bi	1997
A histomorphometric long-term longitudinal study of trabecular bone loss in glucocorticoid-treated patients: prednisone versus deflazacort. Calcified tissue international, 1998, Volume: 62, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents; Biopsy; Bone Density; Female; Glucocorticoids; Humans; Ilium;	1998
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Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. The New England journal of medicine, 1998, Jul-30, Volume: 339, Issue:5 Topics: Adolescent; Aged; Aged, 80 and over; Alendronate; Bone Density; Double-Blind Method; Female; Glucoco	1998
Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. The New England journal of medicine, 1998, Jul-30, Volume: 339, Issue:5 Topics: Adolescent; Aged; Aged, 80 and over; Alendronate; Bone Density; Double-Blind Method; Female; Glucoco	1998
Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. The New England journal of medicine, 1998, Jul-30, Volume: 339, Issue:5 Topics: Adolescent; Aged; Aged, 80 and over; Alendronate; Bone Density; Double-Blind Method; Female; Glucoco	1998
Effect of deflazacort on bone mineral density in renal transplant recipients. Transplantation proceedings, 1998, Volume: 30, Issue:7 Topics: Amino Acids; Biomarkers; Bone Density; Graft Survival; Humans; Immunosuppressive Agents; Kidney Tran	1998
Progression of steroid-associated osteoporosis after heart transplantation. The Annals of thoracic surgery, 1999, Volume: 67, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Bone Density; Calcitonin; Disease Progression; Double-Blind Method;	1999
Prevention of corticosteroid-induced osteoporosis by alfacalcidol. Zeitschrift fur Rheumatologie, 2000, Volume: 59 Suppl 1 Topics: Adjuvants, Immunologic; Adult; Arthritis, Rheumatoid; Asthma; Bone Density; Calcium; Dose-Response R	2000
Bone mass continues to increase at the hip after parathyroid hormone treatment is discontinued in glucocorticoid-induced osteoporosis: results of a randomized controlled clinical trial. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:5 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Calcium; Female; Humans; Middle Aged;	2000
[Glucocorticosteroid induced osteoporosis in patients with rheumatoid arthritis]. Przeglad lekarski, 2000, Volume: 57, Issue:2 Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Density; Female; Glucocorticoids; Humans; Middle Aged; Oste	2000
Risedronate increases bone density and reduces vertebral fracture risk within one year in men on corticosteroid therapy. Calcified tissue international, 2001, Volume: 69, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone and Bones; Bone Density; Calcium Channel Blockers;	2001
Positive effect of etidronate therapy is maintained after drug is terminated in patients using corticosteroids. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2001,Winter, Volume: 4, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Bone Density; Etidronic Acid; Femur Neck; Glucocorticoids; Hip; Huma	2001
Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial. Annals of internal medicine, 2002, Jan-01, Volume: 136, Issue:1 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Disease Progression; F	2002
Summaries for patients. Prednisone for rheumatoid arthritis. Annals of internal medicine, 2002, Jan-01, Volume: 136, Issue:1 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Disease Progression; F	2002
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Article	Year
Studies on the synthesis and anti-Osteoporosis of estrogen-GHRPs linkers. Bioorganic & medicinal chemistry letters, 2003, Jan-06, Volume: 13, Issue:1 Topics: Animals; Body Weight; Calcium; Cross-Linking Reagents; Estrogens; Femur; Growth Hormone-Releasing Ho	2003
Adverse Side Effects Associated with Corticosteroid Therapy: A Study in 39 Patients with Generalized Myasthenia Gravis. Medical science monitor : international medical journal of experimental and clinical research, 2021, Oct-28, Volume: 27 Topics: Adrenal Cortex Hormones; Adult; Affect; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged;	2021
Orbital myositis induced by alendronate: A case report. European journal of neurology, 2023, Volume: 30, Issue:6 Topics: Aged; Alendronate; Diphosphonates; Female; Humans; Orbital Myositis; Osteoporosis; Prednisone	2023
Bone Loss in Inflammatory Rheumatic Musculoskeletal Disease Patients Treated With Low-Dose Glucocorticoids and Prevention by Anti-Osteoporosis Medications. Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:10 Topics: Bone Density; Female; Fractures, Bone; Glucocorticoids; Humans; Inflammation; Longitudinal Studies;	2023
Vitamin D and bisphosphonate therapy in systemic lupus erythematosus patients who receive glucocorticoids: are we offering the best care? Lupus, 2020, Volume: 29, Issue:3 Topics: Adult; Bone Density Conservation Agents; Diphosphonates; Female; Glucocorticoids; Humans; Lupus Eryt	2020
Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients. Annals of the rheumatic diseases, 2021, Volume: 80, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Antirheumatic Agents; Aspirin; Drug Tapering; Europe; Fema	2021
Tanshinol alleviates impaired bone formation by inhibiting adipogenesis via KLF15/PPARγ2 signaling in GIO rats. Acta pharmacologica Sinica, 2018, Volume: 39, Issue:4 Topics: Adipocytes; Adipogenesis; Animals; Body Weight; Bone Marrow; Caffeic Acids; CCAAT-Enhancer-Binding P	2018
Sanggenon C Stimulates Osteoblastic Proliferation and Differentiation, Inhibits Osteoclastic Resorption, and Ameliorates Prednisone-Induced Osteoporosis in Zebrafish Model. Molecules (Basel, Switzerland), 2018, Sep-13, Volume: 23, Issue:9 Topics: Alkaline Phosphatase; Animals; Benzofurans; Cell Differentiation; Cell Line; Cell Proliferation; Chr	2018
Permanent Discontinuation of Glucocorticoids in Polymyalgia Rheumatica Is Uncommon but May Be Enhanced by Amino Bisphosphonates. The Journal of rheumatology, 2019, Volume: 46, Issue:3 Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Bone Density Conservation Agents; Diphosphonates; Ele	2019
Glucocorticoid-induced osteoporosis preventive care in rheumatology patients. Archives of osteoporosis, 2019, 02-05, Volume: 14, Issue:1 Topics: Adult; Bone Density Conservation Agents; Calcium, Dietary; Female; Glucocorticoids; Humans; Male; Mi	2019
Alendronate tracheobronchitis. Annals of the American Thoracic Society, 2013, Volume: 10, Issue:1 Topics: Alendronate; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biopsy; Bone Density Conservation Agen	2013
The disconnect between better quality of glucocorticoid-induced osteoporosis preventive care and better outcomes: a population-based cohort study. The Journal of rheumatology, 2013, Volume: 40, Issue:10 Topics: Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Female; Fractures, Bone; Gl	2013
Challenges in defining quality of care for glucocorticoid-induced osteoporosis: defending good against perfect. The Journal of rheumatology, 2013, Volume: 40, Issue:10 Topics: Bone Density; Female; Fractures, Bone; Glucocorticoids; Humans; Male; Osteoporosis; Prednisone; Qual	2013
Nonuremic calciphylaxis in a patient with rheumatoid arthritis and osteoporosis treated with teriparatide. Journal of the American Academy of Dermatology, 2014, Volume: 70, Issue:2 Topics: Arthritis, Rheumatoid; Bone Density Conservation Agents; Calciphylaxis; Diagnosis, Differential; Dru	2014
[Acute sensory-motor axonal neuropathy (Guillain-Barre syndrome) following vertebroplasty]. Medicina clinica, 2014, Sep-15, Volume: 143, Issue:6 Topics: Accidental Falls; Arthritis, Rheumatoid; Female; Guillain-Barre Syndrome; Humans; Immunocompromised	2014
Are glucocorticoids harmful to bone in early rheumatoid arthritis? Annals of the New York Academy of Sciences, 2014, Volume: 1318 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Glucocorticoids; Humans;	2014
Glucocorticoid-induced osteoporosis in growing rats. Calcified tissue international, 2014, Volume: 95, Issue:4 Topics: Acetates; Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone Resorption; Densitometry;	2014
Relapses in patients with giant cell arteritis: prevalence, characteristics, and associated clinical findings in a longitudinally followed cohort of 106 patients. Medicine, 2014, Volume: 93, Issue:5 Topics: Aged; Aged, 80 and over; Cohort Studies; Disease Progression; Dose-Response Relationship, Drug; Drug	2014
Bone status in glucocorticoid-treated men and women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:1 Topics: Absorptiometry, Photon; Adult; Aged; Anthropometry; Bone Density; Case-Control Studies; Female; Gluc	2016
Orbital Inflammation Secondary to Zoledronic Acid, a Rare Presentation. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2016, Volume: 22, Issue:7 Topics: Aged; Bone Density Conservation Agents; Diphosphonates; Female; Glucocorticoids; Humans; Imidazoles;	2016
Osteoporosis in Pediatric Liver Transplantation. Progress in transplantation (Aliso Viejo, Calif.), 2016, Volume: 26, Issue:4 Topics: Adolescent; Bone Density; Female; Humans; Immunosuppressive Agents; Liver Transplantation; Osteoporo	2016
Both prolonged remission and Lupus Low Disease Activity State are associated with reduced damage accrual in systemic lupus erythematosus. Rheumatology (Oxford, England), 2017, Volume: 56, Issue:1 Topics: Adult; Arthritis; Cataract; Cohort Studies; Diabetes Mellitus; Disease Progression; Female; Glucocor	2017
Long-Term Outcome of Interdisciplinary Management of Patients with Duchenne Muscular Dystrophy Receiving Daily Glucocorticoid Treatment. The Journal of pediatrics, 2017, Volume: 182 Topics: Adolescent; Age Factors; Child; Cohort Studies; Dose-Response Relationship, Drug; Drug Administratio	2017
Percutaneous vertebroplasty in multiple myeloma vertebral involvement. Journal of spinal disorders & techniques, 2008, Volume: 21, Issue:5 Topics: Aged; Aged, 80 and over; Back Pain; Bone Cements; Female; Humans; Lumbar Vertebrae; Male; Middle Age	2008
Biomechanical analysis of combined treatment of high calcium and bisphosphonate in tibia of steroid-treated growing-phase rats. Dental materials journal, 2008, Volume: 27, Issue:5 Topics: Absorptiometry, Photon; Animals; Biomechanical Phenomena; Bone Density; Bone Density Conservation Ag	2008
Prednisone 10 days on/10 days off in patients with Duchenne muscular dystrophy. Journal of neurology, 2009, Volume: 256, Issue:5 Topics: Adolescent; Age Factors; Age of Onset; Akathisia, Drug-Induced; Anti-Inflammatory Agents; Child; Chi	2009
Factors influencing fracture risk, T score, and management of osteoporosis in patients with rheumatoid arthritis in the Consortium of Rheumatology Researchers of North America (CORRONA) registry. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:4 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Density; Bone Density	2009
Rheumatoid arthritis in patient with homozygous haemoglobin C disease. Rheumatology international, 2011, Volume: 31, Issue:6 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Glucocorticoids; Hem	2011
Effect of glucocorticoid-, parathyroid- and thyroid hormones excess on human iliac crest bone matrix insulin-like growth factor (IGF)-I in patients with osteoporosis. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:5 Topics: Bone Density; Bone Matrix; Female; Glucocorticoids; Humans; Hyperparathyroidism; Ilium; Insulin-Like	2010
Development, implementation and evaluation of an electronic medical record prompt for bone density testing. Health informatics journal, 2009, Volume: 15, Issue:4 Topics: Absorptiometry, Photon; Algorithms; Anti-Inflammatory Agents; Attitude of Health Personnel; Bone Den	2009
Screening, prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease - a population-based database study. The clinical respiratory journal, 2010, Volume: 4, Issue:1 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Male; Mass Screeni	2010
Lichenoid dermatosis induced by alendronate: an unusual skin drug reaction. Acta dermato-venereologica, 2010, Volume: 90, Issue:3 Topics: Aged; Alendronate; Biopsy; Bone Density Conservation Agents; Glucocorticoids; Humans; Lichenoid Erup	2010
Osteoporosis screening, prevention, and treatment in systemic lupus erythematosus: application of the systemic lupus erythematosus quality indicators. Arthritis care & research, 2010, Volume: 62, Issue:7 Topics: Adult; Anti-Inflammatory Agents; Bone Density; Bone Density Conservation Agents; Calcium; Dietary Su	2010
Vertebral fractures despite normal spine bone mineral density in a boy with nephrotic syndrome. Pediatric nephrology (Berlin, Germany), 2011, Volume: 26, Issue:1 Topics: Bone and Bones; Bone Density; Child; Glucocorticoids; Humans; Lumbar Vertebrae; Male; Nephrotic Synd	2011
Glucocorticoid-related osteoporotic fractures. Singapore medical journal, 2010, Volume: 51, Issue:12 Topics: Adult; Age Factors; Anti-Inflammatory Agents; Female; Femoral Fractures; Fractures, Bone; Glucocorti	2010
Acroosteolysis in systemic lupus erythematosus. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:2 Topics: Acro-Osteolysis; Adult; Cyclophosphamide; Female; Finger Phalanges; Humans; Lupus Erythematosus, Sys	2011
Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis. PloS one, 2012, Volume: 7, Issue:4 Topics: Adipocytes; Adipogenesis; Animals; Benzofurans; beta Catenin; Bone and Bones; Bone Marrow Cells; Bon	2012
Quality assurance study of the use of preventative therapies in glucocorticoid-induced osteoporosis in early inflammatory arthritis: results from the CATCH cohort. Rheumatology (Oxford, England), 2012, Volume: 51, Issue:9 Topics: Arthritis, Rheumatoid; Bone Density Conservation Agents; Calcium; Cohort Studies; Databases, Factual	2012
[Skeletal effect of xianzhen gubao on preventing prednisone-induced osteoporosis in male rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1999, Volume: 24, Issue:9 Topics: Animals; Capsules; Drug Combinations; Drugs, Chinese Herbal; Male; Osteogenesis; Osteoporosis; Phyto	1999
Multiple vertebral compression fractures in a patient treated with corticosteroids for cystic fibrosis. Canadian journal of surgery. Journal canadien de chirurgie, 2002, Volume: 45, Issue:5 Topics: Adolescent; Anti-Inflammatory Agents; Casts, Surgical; Cystic Fibrosis; Fatal Outcome; Fractures, Sp	2002
Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: rates and predictors of care in an academic rheumatology practice. Arthritis and rheumatism, 2002, Volume: 46, Issue:12 Topics: Academic Medical Centers; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Clinical	2002
[Giant cell arteritis after the age of 75]. Annales de medecine interne, 2002, Volume: 153, Issue:6 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Monitoring; F	2002
Effects of prednisone on bone mineral density and biomechanical characteristics of the femora and lumbar vertebras in rats. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:2 Topics: Animals; Biomechanical Phenomena; Bone Density; Femur; Glucocorticoids; Lumbar Vertebrae; Male; Oste	2003
Long-term follow-up of bone mineral density in Addison's disease. Clinical endocrinology, 2003, Volume: 58, Issue:5 Topics: Addison Disease; Aged; Alkaline Phosphatase; Analysis of Variance; Bone and Bones; Bone Density; Fem	2003
Are children with idiopathic nephrotic syndrome at risk for metabolic bone disease? American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:6 Topics: Absorptiometry, Photon; Anti-Inflammatory Agents; Bone Density; Bone Diseases, Metabolic; Calcium, D	2003
Low dosage adrenocorticosteroid maintenance therapy of rheumatoid arthritis: icidence of peptic ulcer and osteoporosis. American practitioner and digest of treatment, 1961, Volume: 12 Topics: Arthritis; Arthritis, Rheumatoid; Humans; Osteoporosis; Peptic Ulcer; Prednisone	1961
[On the action of certain anabolic drugs and prednisone in the chronically ill and aged patient with osteoporosis]. Schweizerische medizinische Wochenschrift, 1962, Oct-13, Volume: 92 Topics: Calcium; Calcium, Dietary; Chronic Disease; Humans; Osteoporosis; Prednisone; Steroids; Testosterone	1962
TREATMENT OF OSTEOPOROSIS WITH AN ANABOLIC COMPOUND AND L-LYSINE. Delaware medical journal, 1963, Volume: 35 Topics: Amino Acids; Anabolic Agents; Appetite; Arthritis; Arthritis, Rheumatoid; Dietary Proteins; Emotions	1963
CORTICOSTEROID OSTEOPOROSIS AND TREATMENT WITH ANABOLIC HORMONE. Acta medica Scandinavica, 1963, Volume: 174 Topics: Adrenal Cortex Hormones; Anabolic Agents; Arthritis; Arthritis, Rheumatoid; Hormones; Osteoporosis;	1963
[ATTEMPTED EVALUATION OF THE OSSEOUS HAZARD IN ASTHMATICS SUBJECTED TO LONG-TERM CORTICOID TREATMENT]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1963, Oct-14, Volume: 39 Topics: Adrenal Cortex Hormones; Asthma; Bone and Bones; Cortisone; Dexamethasone; Hydrocortisone; Methylpre	1963
[CONGENITAL HYPOPLASTIC STATE OF THE HEMATOPOIETIC SYSTEM IN CHILDREN]. Pediatriia, 1963, Volume: 42 Topics: Anemia; Anemia, Aplastic; Ascorbic Acid; Bilirubin; Blood Cell Count; Blood Chemical Analysis; Blood	1963
THE EFFECTS OF SODIUM FLORIDE ON CALCIUM METABOLISM OF SUBJECTS WITH METABOLIC BONE DISEASES. The Journal of clinical investigation, 1964, Volume: 43 Topics: Blood; Body Fluids; Bone Diseases, Metabolic; Calcium; Diet; Feces; Fluorides; Geriatrics; Metabolis	1964
[VERTEBRAL FRACTURES DURING CORTICOSTEROID THERAPY]. Radiologia clinica, 1964, Volume: 33 Topics: Adrenal Cortex Hormones; Dexamethasone; Fractures, Bone; Humans; Lumbar Vertebrae; Methyltestosteron	1964
BILATERAL POPLITEAL CYSTS IN A PATIENT WITH RHEUMATOID ARTHRITIS. New York state journal of medicine, 1964, Aug-15, Volume: 64 Topics: Arthritis; Arthritis, Rheumatoid; Cervical Vertebrae; Cysts; Drug Therapy; Elbow; Elbow Joint; Human	1964
CORTICOSTEROID THERAPY IN RHEUMATOID ARTHRITIS. CRITERIA AND RESULTS. Postgraduate medicine, 1964, Volume: 36 Topics: Arthritis; Arthritis, Rheumatoid; Corticosterone; Dosage Forms; Drug Therapy; Fractures, Bone; Geria	1964
INTERMITTENT CORTICOSTEROID THERAPY OF JUVENILE RHEUMATOID ARTHRITIS. Arthritis and rheumatism, 1964, Volume: 7 Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Arthritis; Arthr	1964
THE SIDE-EFFECTS OF CORTICOSTEROIDS. Annals of physical medicine, 1964, Volume: 8 Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Arthritis; Arthritis, Rheumatoid; Dosage Forms; Fra	1964
Steroid osteoporosis. Proceedings of the Royal Society of Medicine, 1960, Volume: 53 Topics: Humans; Osteoporosis; Prednisone; Steroids; Triamcinolone	1960
Bone mineral density changes in women with systemic lupus erythematosus. Clinical rheumatology, 2003, Volume: 22, Issue:4-5 Topics: Absorptiometry, Photon; Adult; Age Distribution; Bone Density; Bulgaria; Calcium; Case-Control Studi	2003
Suggested guidelines for evaluation and treatment of glucocorticoid-induced osteoporosis for the Department of Veterans Affairs. Archives of internal medicine, 2003, Nov-24, Volume: 163, Issue:21 Topics: Absorptiometry, Photon; Calcium; Diphosphonates; Fractures, Bone; Glucocorticoids; Humans; Osteoporo	2003
Experimental study on cheng zai wan for treatment of necrosis of the femoral head. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2003, Volume: 23, Issue:4 Topics: Animals; Animals, Newborn; Drug Combinations; Drugs, Chinese Herbal; Female; Femur Head; Femur Head	2003
[Steroid-responsive nephrotic syndrome in IgA nephropathy]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3 Topics: Biopsy; Cyclophosphamide; Cyclosporine; Diabetes Mellitus; Drug Therapy, Combination; Glomerulonephr	2004
The effect of intravenous zoledronic acid on glucocorticoid-induced multiple vertebral fractures in juvenile systemic lupus erythematosus. Revista do Hospital das Clinicas, 2004, Volume: 59, Issue:5 Topics: Adolescent; Azathioprine; Bone Density; Bone Density Conservation Agents; Cervical Vertebrae; Diphos	2004
[Bone mineral density and biomechanical effects of Chinese herbal drug Yanhuogubao on experimental osteoporosis in rats]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2002, Volume: 25, Issue:11 Topics: Animals; Biomechanical Phenomena; Bone Density; Bone Resorption; Drugs, Chinese Herbal; Femur; Lumba	2002
Correlation of different bone markers with bone density in patients with rheumatic diseases on glucocorticoid therapy. Rheumatology international, 2006, Volume: 26, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Density; Bone Di	2006
Practice patterns in patients at risk for glucocorticoid-induced osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:12 Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Asthma; Bone De	2005
Quantitative ultrasonometry of the calcaneus in children with juvenile idiopathic arthritis. Rheumatology (Oxford, England), 2006, Volume: 45, Issue:10 Topics: Adolescent; Analysis of Variance; Arthritis, Juvenile; Body Height; Body Mass Index; Body Weight; Ca	2006
Trends in prevention of glucocorticoid-induced osteoporosis. The Journal of rheumatology, 2006, Volume: 33, Issue:8 Topics: Adolescent; Adult; Aged; Bone Density; Bone Density Conservation Agents; Female; Glucocorticoids; Hu	2006
Osteoporosis management in patients with rheumatoid arthritis: Evidence for improvement. Arthritis and rheumatism, 2006, Dec-15, Volume: 55, Issue:6 Topics: Aged; Arthritis, Rheumatoid; Bone Density; Comorbidity; Female; Glucocorticoids; Guideline Adherence	2006
Prednisone-induced osteoporosis: an overlooked and undertreated adverse effect. The Journal of the American Osteopathic Association, 2006, Volume: 106, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Female; Glucocorticoids; Humans; Male; Middle Aged; Ost	2006
Barriers in the management of glucocorticoid-induced osteoporosis. Arthritis and rheumatism, 2007, Feb-15, Volume: 57, Issue:1 Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Calcium, Dietary; Clinical Competence; Female; Focus	2007
Teriparatide or alendronate in glucocorticoid-induced osteoporosis. The New England journal of medicine, 2008, Mar-20, Volume: 358, Issue:12 Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Glucocorticoids; Humans; Osteoporosis;	2008
Bone mineral density in children exposed to chronic glucocorticoid therapy. Clinical pediatrics, 2008, Volume: 47, Issue:5 Topics: Adolescent; Arthritis, Juvenile; Bone Density; Calcium, Dietary; Child; Child, Preschool; Cross-Sect	2008
Bone dynamics of rheumatoid arthritis treated with adrenal corticosteroids. Arthritis and rheumatism, 1967, Volume: 10, Issue:3 Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Development; Bone Resorption; Female; Humans; Male; Middle	1967
Body cell mass during long-term treatment with cortisone and anabolic steroids in asthmatic subjects. Acta endocrinologica, 1967, Volume: 55, Issue:2 Topics: Adult; Aged; Asthma; Basal Metabolism; Body Fluids; Body Weight; Cortisone; Female; Humans; Male; Mi	1967
[Long-term osteoporosis with multiple fractures as the early monosymptomatic stage of multiple myeloma]. Onkologie, 1984, Volume: 7, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fractures, Spontaneous; Hum	1984
Bone loss after glucocorticoid therapy. Calcified tissue international, 1984, Volume: 36, Issue:4 Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Osteoporosis; Prednisone; Pregnenediones; Time Facto	1984
Prevalence of decreased bone mass in rheumatoid arthritis. Relation to anti-inflammatory treatment. Clinical rheumatology, 1984, Volume: 3, Issue:2 Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone and Bones; Calcium; Female; Gold;	1984
[Practical aspects of glucocorticosteroid therapy]. Schweizerische medizinische Wochenschrift, 1984, Mar-17, Volume: 114, Issue:11 Topics: Calcium; Dose-Response Relationship, Drug; Drug Administration Schedule; Glucocorticoids; Humans; In	1984
Iatrogenic morbidity accompanying suppression of temporal arteritis by adrenal corticosteroids. Annals of ophthalmology, 1984, Volume: 16, Issue:3 Topics: Adrenal Cortex Hormones; Aged; Drug Administration Schedule; Female; Fractures, Spontaneous; Giant C	1984
Glucocorticoid-induced osteoporosis. The New England journal of medicine, 1983, Aug-04, Volume: 309, Issue:5 Topics: Bone Resorption; Female; Glucocorticoids; Humans; Osteoporosis; Prednisone	1983
Complications of steroid therapy. Delaware medical journal, 1981, Volume: 53, Issue:9 Topics: Administration, Oral; Administration, Topical; Adult; Female; Granulocytes; Heart Failure; Humans; H	1981
The effect of systemic lupus erythematosus and long-term steroid therapy on bone mass in pre-menopausal women. British journal of rheumatology, 1995, Volume: 34, Issue:8 Topics: Adult; Bone Density; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Femur; Follo	1995
Renal transplantation and osteoporosis. Archives of disease in childhood, 1995, Volume: 72, Issue:6 Topics: Adult; Bone Density; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Kidn	1995
Glucocorticoid-induced osteoporosis. Hospital practice (1995), 1995, Aug-15, Volume: 30, Issue:8 Topics: Adolescent; Aged; Calcium; Combined Modality Therapy; Diphosphonates; Drug Therapy, Combination; Exe	1995
[Iatrogenic osteoporsis: six case reports]. Zhonghua nei ke za zhi, 1994, Volume: 33, Issue:10 Topics: Adult; Arthritis, Rheumatoid; Asthma; Bone Resorption; Female; Follow-Up Studies; Humans; Iatrogenic	1994
[Effect of total coumarins from dried fruits of Cnidium monnieri on glucocorticoid-induced osteoporosis in rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:4 Topics: Animals; Bone Resorption; Coumarins; Drugs, Chinese Herbal; Male; Osteoporosis; Prednisone; Rats; Ra	1994
MR imaging of multiple myeloma in tumour mass measurement at diagnosis and during treatment. Acta radiologica (Stockholm, Sweden : 1987), 1995, Volume: 36, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Female; Femur; Humans; Magnetic R	1995
Prednisone in managing rheumatoid arthritis. Annals of internal medicine, 1994, Apr-15, Volume: 120, Issue:8 Topics: Arthritis, Rheumatoid; Humans; Osteoporosis; Prednisone	1994
The efficacy of combined treatment with prednisone and cyclosporine in patients with pemphigus: preliminary study. Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:5 Pt 1 Topics: Administration, Oral; Adult; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Gin	1994
Spinal osteomyelitis due to Mycobacterium avium-intracellulare in an elderly man with steroid-induced osteoporosis. Spine, 1993, Oct-01, Volume: 18, Issue:13 Topics: Aged; Diagnosis, Differential; Humans; Lupus Erythematosus, Systemic; Male; Mycobacterium avium-intr	1993
Fractures in rheumatoid arthritis: an evaluation of associated risk factors. The Journal of rheumatology, 1993, Volume: 20, Issue:10 Topics: Aging; Arthritis, Rheumatoid; Body Mass Index; Disabled Persons; Female; Fractures, Bone; Humans; Ma	1993
Reversibility of exogenous corticosteroid-induced bone loss. The European respiratory journal, 1993, Volume: 6, Issue:1 Topics: Adult; Bone Density; Chronic Disease; Female; Humans; Lung Diseases; Male; Osteoporosis; Prednisone;	1993
Osteoporosis after cardiac transplantation. The American journal of medicine, 1993, Volume: 94, Issue:3 Topics: Absorptiometry, Photon; Bone Density; Cyclosporine; Female; Femur Neck; Heart Transplantation; Human	1993
Differential effects of glucocorticoids on cortical appendicular and cortical vertebral bone mineral content. Calcified tissue international, 1993, Volume: 52, Issue:1 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Analysis of Variance; Arthritis, Rheumatoid; Bone D	1993
Testosterone treatment of men treated with glucocorticoids. Archives of internal medicine, 1996, Jun-10, Volume: 156, Issue:11 Topics: Asthma; Bone Density; Glucocorticoids; Humans; Male; Osteoporosis; Prednisone; Testosterone	1996
Long-term bone loss in kidney transplant recipients: a cross-sectional and longitudinal study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:1 Topics: Adult; Bone Density; Bone Diseases, Metabolic; Cross-Sectional Studies; Female; Follow-Up Studies; G	1996
[Experimental study on zhuanggu shengbao in preventing hormone-induced osteoporosis of rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996, Volume: 16, Issue:2 Topics: Animals; Bone Density; Bone Resorption; Drugs, Chinese Herbal; Male; Osteoporosis; Prednisone; Rando	1996
Osteoporosis in lung transplantation candidates with end-stage pulmonary disease. The American journal of medicine, 1996, Volume: 101, Issue:3 Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Bone Density; Cystic Fibrosis; Female; Fractures, S	1996
Methods to score vertebral deformities in patients with rheumatoid arthritis. British journal of rheumatology, 1997, Volume: 36, Issue:2 Topics: Aged; Anthropometry; Arthritis, Rheumatoid; Bone and Bones; Female; Glucocorticoids; Humans; Lumbar	1997
Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:3 Pt 1 Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Age Factors; Aged; Anti-	1998
[Experimental study on antagonizing action of herba Epimedii on side effects induced by glucocorticoids]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1996, Volume: 21, Issue:12 Topics: Adrenal Cortex; Animals; Atrophy; Drugs, Chinese Herbal; Magnoliopsida; Male; Osteoporosis; Phytothe	1996
Effects of total coumarins of Cnidium monnieri on bone density and biomechanics of glucocorticoids-induced osteoporosis in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:6 Topics: Animals; Apiaceae; Biomechanical Phenomena; Bone Density; Coumarins; Femur; Male; Osteoporosis; Pred	1997
Polymorphism of the vitamin D receptor gene and corticosteroid-related osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 9, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone De	1999
Prevention of glucocorticoid-induced osteoporosis: provider practice at an urban county hospital. The American journal of medicine, 1999, Volume: 107, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Calcium; Estrogen Replacement Therapy; Fem	1999
A marked increase in bone mineral density in a patient with glucocorticoid-induced osteoporosis. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 1999,Winter, Volume: 2, Issue:4 Topics: Absorptiometry, Photon; Aged; Bone Density; Bone Neoplasms; Glucocorticoids; Humans; Male; Osteoporo	1999
Glucocorticoid-induced osteoporosis: is the bone density decrease the only explanation? Joint bone spine, 2000, Volume: 67, Issue:2 Topics: Bone Density; Case-Control Studies; Female; Fractures, Spontaneous; Glucocorticoids; Humans; Middle	2000
Drugs for rheumatoid arthritis. The Medical letter on drugs and therapeutics, 2000, Jul-10, Volume: 42, Issue:1082 Topics: Administration, Oral; Adrenal Cortex Hormones; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; An	2000
Management of glucocorticoid-induced osteoporosis in male veterans. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:12 Topics: Adult; Aged; Bone Density; Calcium; Dietary Supplements; Disease Management; Glucocorticoids; Gonada	2000
Posttransplant bone disease: evidence for a high bone resorption state. Transplantation, 2000, Dec-27, Volume: 70, Issue:12 Topics: Adult; Aged; Amino Acids; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cross-Se	2000
Bone mass and mineral metabolism in liver transplant patients treated with FK506 or cyclosporine A. Calcified tissue international, 2001, Volume: 68, Issue:2 Topics: Absorptiometry, Photon; Azathioprine; Bone Density; Cyclosporine; Drug Therapy, Combination; Femur N	2001
[Non-specific inflammation of the respiratory tract in a female patient with inflammatory bowel disease and osteoporosis]. Nederlands tijdschrift voor geneeskunde, 2001, May-26, Volume: 145, Issue:21 Topics: Administration, Inhalation; Adult; Anti-Inflammatory Agents; Asthma; Colectomy; Contraindications; D	2001
Change in bone mineral density in patients with rheumatoid arthritis during the first decade of the disease. Arthritis and rheumatism, 2001, Volume: 44, Issue:6 Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumat	2001
Prevalence and determinants of osteoporosis drug prescription among patients with high exposure to glucocorticoid drugs. The American journal of managed care, 2001, Volume: 7, Issue:6 Topics: Adult; Aged; Alendronate; Calcitonin; California; Drug Prescriptions; Drug Utilization Review; Etidr	2001
Fractures in adults on systemic steroid therapy: which prophylaxis? Prescrire international, 1999, Volume: 8, Issue:43 Topics: Arthritis, Rheumatoid; Asthma; Bone Density; Calcitonin; Calcium; Clinical Trials as Topic; Diphosph	1999
Audit of the management of suspected giant cell arteritis in a large teaching hospital. Internal medicine journal, 2002, Volume: 32, Issue:7 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biopsy; Diagnosis, Differential; Female; Giant Ce	2002
Osteoscintigraphic changes in kidney-transplanted patients. Nephron, 1978, Volume: 21, Issue:2 Topics: Adult; Bone and Bones; Bone Diseases; Female; Humans; Kidney Failure, Chronic; Kidney Transplantatio	1978
Orthopedic complications of renal transplantation in children. Transplantation proceedings, 1979, Volume: 11, Issue:1 Topics: Adolescent; Age Factors; Child; Dose-Response Relationship, Drug; Female; Humans; Immunosuppression	1979
[Complication following long-term use of corticosteroid preparations]. Vrachebnoe delo, 1977, Issue:11 Topics: Female; Humans; Middle Aged; Osteoporosis; Prednisolone; Prednisone	1977
Effect of 1alpha-hydroxycholecalciferol in senile osteoporosis and in bone loss following prednisone treatment. Israel journal of medical sciences, 1977, Volume: 13, Issue:3 Topics: Aged; Aging; Calcium; Humans; Hydroxycholecalciferols; Hydroxyproline; Osteoporosis; Prednisone	1977
Steroid myopathy in connective tissue disease. The American journal of medicine, 1976, Volume: 61, Issue:4 Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Child; Collagen Diseases; Creatine Kinase; Cre	1976
[Problems raised by corticoid therapy in children]. La Revue du praticien, 1975, Mar-11, Volume: 25, Issue:15 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Insufficiency; Age Factors; Animals; Chickenpox; Ch	1975
Estrogen and progesterone replacement therapy reduces glucocorticoid-induced bone loss. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:9 Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Estrogen Replacement Therapy; Estrogens, Conjugat	1992
Corticosteroid-induced osteoporosis: effects of a treatment with slow-release sodium fluoride. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1992, Volume: 2, Issue:6 Topics: Adrenal Cortex Hormones; Aged; Bone Density; Delayed-Action Preparations; Female; Humans; Male; Midd	1992
[Comparison of the effects of sodium fluoride and calcidiol on the remodeling of the endosteal surface of the rib cortex in dogs after administration of prednisone]. Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:2 Topics: Animals; Bone Remodeling; Calcifediol; Disease Models, Animal; Dogs; Drug Synergism; Osteoporosis; P	1992
Vertebral osteoporosis in rheumatoid arthritis patients: effect of low dose prednisone therapy. British journal of rheumatology, 1992, Volume: 31, Issue:8 Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Osteoporosis; Prednisone	1992
Vertebral osteoporosis in rheumatoid arthritis patients: effect of low dose prednisone therapy. British journal of rheumatology, 1992, Volume: 31, Issue:2 Topics: Arthritis, Rheumatoid; Bone Density; Dose-Response Relationship, Drug; Female; Humans; Male; Menopau	1992
Vertebral fractures in steroid dependent asthma and involutional osteoporosis: a comparative study. Thorax, 1991, Volume: 46, Issue:11 Topics: Adult; Aged; Asthma; Bone Density; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Osteoporosis	1991
Treatment of elderly-onset rheumatoid arthritis. Journal of the American Geriatrics Society, 1991, Volume: 39, Issue:10 Topics: Aged; Arthritis, Rheumatoid; Cardiovascular Diseases; Humans; Osteoporosis; Prednisone	1991
Endosteal implants in a patient with corticosteroid dependence. The Journal of oral implantology, 1991, Volume: 17, Issue:4 Topics: Alveolar Process; Dental Implantation, Endosseous; Dental Implants; Female; Humans; Middle Aged; Ost	1991
Effects of medroxyprogesterone acetate on some parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis. Bone and mineral, 1991, Volume: 13, Issue:2 Topics: Aged; Alkaline Phosphatase; Calcifediol; Calcitonin; Calcitriol; Calcium; Humans; Insulin-Like Growt	1991
Intestinal calcium absorption and parathyroid hormone secretion in asthmatic patients on prolonged oral or inhaled steroid treatment. The European respiratory journal, 1991, Volume: 4, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Asthma; Beclomethasone; Calcium; Female; Humans; I	1991
Bone loss in patients with rheumatoid arthritis--effect of steroids measured by low dose quantitative computed tomography. Rheumatology international, 1991, Volume: 11, Issue:1 Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Density; Female; Humans; Menopause; Middle Aged; Osteoporos	1991
Predictors of fractures in early rheumatoid arthritis. The Journal of rheumatology, 1991, Volume: 18, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Fractures, Bone; Humans;	1991
Prevention of corticosteroid-induced osteoporosis with salmon calcitonin in sarcoid patients. Calcified tissue international, 1991, Volume: 49, Issue:2 Topics: Administration, Intranasal; Adult; Bone Density; Calcitonin; Female; Follow-Up Studies; Humans; Inje	1991
Effective therapy of glucocorticoid-induced osteoporosis with medroxyprogesterone acetate. Calcified tissue international, 1990, Volume: 46, Issue:5 Topics: Aged; Asthma; Bone Density; Humans; Luteinizing Hormone; Male; Medroxyprogesterone; Medroxyprogester	1990
Natural and corticosteroid-induced osteoporosis in sarcoidosis: prevention, treatment, follow up and reversibility. Sarcoidosis, 1990, Volume: 7, Issue:2 Topics: Anti-Inflammatory Agents; Calcitonin; Humans; Osteoporosis; Prednisone; Pregnenediones; Sarcoidosis	1990
The long-term treatment of steroid osteoporosis with fluoride. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5 Suppl 1 Topics: Adult; Aged; Bone Density; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteoporosis; Prednis	1990
Bone mass in women with primary biliary cirrhosis: the relation with histological stage and use of glucocorticoids. Gastroenterology, 1990, Volume: 99, Issue:4 Topics: Bone Density; Female; Humans; Liver; Liver Cirrhosis, Biliary; Middle Aged; Osteoporosis; Prednisone	1990
Change of serum calcitonin in patients receiving glucocorticoids: an acute phase study. The Netherlands journal of medicine, 1990, Volume: 36, Issue:5-6 Topics: Acute Disease; Aged; Calcitonin; Calcium; Female; Giant Cell Arteritis; Humans; Male; Middle Aged; O	1990
Insulin-like growth factor 1 and bone turnover in glucocorticoid-treated and control subjects. Clinical endocrinology, 1989, Volume: 30, Issue:4 Topics: Adult; Alkaline Phosphatase; Asthma; Bone and Bones; Female; Humans; Hydroxyproline; Insulin-Like Gr	1989
[Complications of long-term corticotherapy: how to prevent?]. Pediatrie, 1989, Volume: 44, Issue:2 Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Growth; Humans; Osteoporosis; Prednisolone; Predniso	1989
Serum osteocalcin in the assessment of corticosteroid induced osteoporosis. Effect of long and short term corticosteroid treatment. The Journal of rheumatology, 1989, Volume: 16, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Calcium-Binding Proteins; Co	1989
New therapeutic approaches in asthma. The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:4 Topics: Adrenergic beta-Agonists; Aerosols; Airway Obstruction; Aspirin; Asthma; Bronchi; Bronchodilator Age	1986
Prednisone-induced bone loss in sarcoidosis: a risk especially frequent in postmenopausal women. Sarcoidosis, 1988, Volume: 5, Issue:2 Topics: Adult; Aged; Female; Humans; Lumbar Vertebrae; Male; Menopause; Middle Aged; Minerals; Osteoporosis;	1988
Bone protection with salmon calcitonin (sCT) in the long-term steroid therapy of chronic sarcoidosis. Sarcoidosis, 1988, Volume: 5, Issue:2 Topics: Adult; Calcitonin; Chronic Disease; Female; Humans; Male; Menopause; Middle Aged; Minerals; Osteopor	1988
Effects of moderate physical training on prednisone-induced protein wasting: a study of whole-body and bone protein metabolism. Metabolism: clinical and experimental, 1988, Volume: 37, Issue:3 Topics: Adult; Body Weight; Bone and Bones; Calcium-Binding Proteins; Humans; Male; Methylhistidines; Osteoc	1988
Researching osteoporosis in prednisone treated sarcoid patients. Sarcoidosis, 1987, Volume: 4, Issue:1 Topics: Bone and Bones; Female; Humans; Lumbar Vertebrae; Male; Minerals; Osteoporosis; Prednisone; Sarcoido	1987
Monitoring fluoride therapy in osteoporosis by dual photon absorptiometry. Bone, 1987, Volume: 8, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Estrogens; Female; Humans; Male; Middle Aged; Minera	1987
Supraacetabular and femoral head stress fracture during fluoride treatment. Gerontology, 1987, Volume: 33, Issue:5 Topics: Acetabulum; Aged; Female; Femoral Neck Fractures; Fractures, Spontaneous; Humans; Osteoporosis; Pred	1987
Calcium supplements in the prevention of steroid-induced osteoporosis. The American journal of clinical nutrition, 1986, Volume: 44, Issue:2 Topics: Adolescent; Adult; Aged; Bone and Bones; Calcium; Female; Humans; Hydroxyproline; Male; Middle Aged;	1986
Drug-induced arthropathy and necrosis of the femoral head. The Journal of bone and joint surgery. British volume, 1973, Volume: 55, Issue:2 Topics: Adult; Aged; Alcoholism; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Asthma; Bone Regeneration;	1973
Osteoporosis and long-term corticosteroid therapy. British medical journal, 1973, Jul-21, Volume: 3, Issue:5872 Topics: Activation Analysis; Adrenal Cortex Hormones; Adult; Body Composition; Calcium; Calcium Isotopes; Fe	1973
[Chronic viral hepatitis in childhood. 24 cases including 5 sibling pairs]. Infection, 1973, Volume: 1, Issue:4 Topics: Adolescent; Agammaglobulinemia; Age Factors; Autoantibodies; Azathioprine; Biopsy; Child; Child, Pre	1973
[What is guaranteed in the therapy of chronic hepatitis?]. Der Internist, 1973, Volume: 14, Issue:12 Topics: Acne Vulgaris; Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Diabetes Mellitus; Gastrointe	1973
[A contribution to A-hypervitaminosis]. Helvetica paediatrica acta, 1968, Volume: 23, Issue:2 Topics: Age Determination by Skeleton; Alkaline Phosphatase; Anorexia Nervosa; Bone and Bones; Calcium; Chil	1968
Vertebral compression in childhood leukemia. American journal of diseases of children (1960), 1973, Volume: 125, Issue:6 Topics: Age Factors; Child; Female; Fractures, Spontaneous; Humans; Leukemia, Lymphoid; Male; Mercaptopurine	1973
Metabolic studies of bone in uremia before and after treatment. Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4 Topics: Adult; Azathioprine; Bone and Bones; Bone Resorption; Carbon Isotopes; Chronic Kidney Disease-Minera	1972
Renal transplantation in children. Analysis of 25 consecutive transplants in 19 recipients. Archives of disease in childhood, 1972, Volume: 47, Issue:254 Topics: Adolescent; Azathioprine; Child; Female; Graft Rejection; Histocompatibility Testing; Humans; Immuno	1972
Cyclophosphamide in the treatment of pemphigus vulgaris and bullous pemphigoid. Archives of dermatology, 1972, Volume: 106, Issue:5 Topics: Adult; Aged; Alopecia; Cataract; Child; Cyclophosphamide; Diabetes Mellitus; Female; Humans; Leukope	1972
Necrosis of the femoral head occurring in association with corticosteroid medication. Archivum chirurgicum Neerlandicum, 1972, Volume: 24, Issue:2 Topics: Adult; Anemia, Aplastic; Female; Femur Head Necrosis; Fractures, Spontaneous; Humans; Lupus Erythema	1972
[Corticoid long-term therapy. Desired and undesired effects]. Fortschritte der Medizin, 1973, Apr-26, Volume: 91, Issue:12 Topics: Anti-Inflammatory Agents; Diabetes Mellitus; Edema; Eye Diseases; Glucocorticoids; Humans; Immunosup	1973
[Hazards of local corticoid therapy]. Zeitschrift fur arztliche Fortbildung, 1973, Aug-15, Volume: 67, Issue:16 Topics: Administration, Topical; Adult; Aged; Ankylosis; Anti-Inflammatory Agents; Bursitis; Cellulitis; Dex	1973
Treatment of pemphigus and pemphigoid with azathioprine. Dermatologica, 1973, Volume: 147, Issue:3 Topics: Aged; Azathioprine; Candidiasis, Cutaneous; Drug Therapy, Combination; Female; Follow-Up Studies; Hu	1973
Letter: Calcitonin in steroid-induced osteoporosis. The New England journal of medicine, 1974, Jun-27, Volume: 290, Issue:26 Topics: Aged; Calcitonin; Calcium; Diet Therapy; Female; Humans; Hydroxyproline; Injections, Subcutaneous; L	1974
Renal homotransplantation in pediatric patients. Pediatrics, 1971, Volume: 47, Issue:3 Topics: Adolescent; Affective Symptoms; Age Factors; Cadaver; Child; Child Behavior Disorders; Child, Presch	1971
The relationships between adrenal cortical steroids, parathyroid extract, and calcitonin. Pediatrics, 1971, Volume: 47, Issue:1 Topics: Adrenal Cortex Hormones; Animals; Bone Transplantation; Calcification, Physiologic; Calcitonin; Calc	1971
[Treatment of glucocorticoid osteoporosis using sodium fluoride]. Das Deutsche Gesundheitswesen, 1971, Dec-16, Volume: 26, Issue:51 Topics: Fluorides; Glucocorticoids; Humans; Long-Term Care; Male; Middle Aged; Osteoporosis; Prednisone; Sod	1971
Clinical observations on the use of adrenal steroids. Comments on side effects and approaches to avoiding them. Clinical pediatrics, 1972, Volume: 11, Issue:7 Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Child; Glucocorticoids; Growth Disorders; Half-Life	1972
[Bone metabolism and rheumatoid arthritis]. Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1972, Volume: 2 Topics: Adult; Aged; Alkaline Phosphatase; Analysis of Variance; Arthritis, Rheumatoid; Bone and Bones; Calc	1972
[Studies on calcium metabolism in humans with the aid of a whole body counter. Whole body retention of Ca47 in the healthy and in patients with tumors and other diseases]. Radiologia clinica et biologica, 1971, Volume: 40, Issue:3 Topics: Adult; Age Factors; Aged; Bone Diseases; Bone Neoplasms; Calcium; Calcium Isotopes; Cortisone; Femal	1971
[Clinical and x-ray studies on the development of osteopathy of calcipenic genesis in childhood]. Radiologia diagnostica, 1971, Volume: 12, Issue:3 Topics: Adolescent; Bone Diseases, Developmental; Calcium Metabolism Disorders; Child; Child, Preschool; Hum	1971
[Skeletal deposition of radiostrontium in osteoporosis. Scintigraphic examination using 85 Sr]. Schweizerische medizinische Wochenschrift, 1971, Oct-30, Volume: 101, Issue:43 Topics: Adult; Aged; Bone and Bones; Calcium; Cushing Syndrome; Female; Fractures, Bone; Humans; Male; Middl	1971
The treatment of cryptogenic fibrosing alveolitis with immunosuppressant drugs. The Quarterly journal of medicine, 1971, Volume: 40, Issue:158 Topics: Adult; Agglutination Tests; Antibodies, Antinuclear; Azathioprine; Chlorambucil; Complement Fixation	1971
Case of extreme hypersensitivity to almost all antituberculous drugs. British medical journal, 1969, Nov-29, Volume: 4, Issue:5682 Topics: Aminosalicylic Acids; Antitubercular Agents; Cortisone; Drug Hypersensitivity; Ethambutol; Fludrocor	1969
Rheumatoid arthritis and papilledema. Résumé of case. Mayo Clinic proceedings, 1970, Volume: 45, Issue:9 Topics: Arthritis, Rheumatoid; Cerebrospinal Fluid; Diagnosis, Differential; Endocarditis, Subacute Bacteria	1970
Cyclophosphamide and pemphigus vulgaris. Archives of dermatology, 1971, Volume: 103, Issue:2 Topics: Adrenal Cortex Hormones; Blood Protein Electrophoresis; Cyclophosphamide; Diabetes Complications; Hu	1971
[Effect of corticoids on bone metabolism]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Jun-01, Volume: 26, Issue:11 Topics: Adrenal Cortex Hormones; Animals; Bone and Bones; Calcium; Female; Osteoporosis; Photometry; Prednis	1971
[Primary sclerosing cholangitis]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Jul-10, Volume: 91, Issue:19 Topics: Alkaline Phosphatase; Bilirubin; Cholangiography; Cholangitis; Female; Humans; Middle Aged; Osteopor	1971
[The mineralization degree of the spine after long-term corticosteroid therapy of chronic bronchial asthma]. Klinische Wochenschrift, 1967, Jun-01, Volume: 45, Issue:11 Topics: Adolescent; Adult; Aged; Asthma; Chronic Disease; Female; Humans; Hydroxyapatites; Lumbar Vertebrae;	1967
[Problems of long-term prednisone therapy in existing senile osteoporosis]. Zeitschrift fur Alternsforschung, 1967, Volume: 20, Issue:3 Topics: Aged; Asthma; Female; Fractures, Spontaneous; Humans; Middle Aged; Osteomalacia; Osteoporosis; Predn	1967
[Role of corticotherapy in vertebral osteoporosis in rheumatoid arthritis]. Revue du rhumatisme et des maladies osteo-articulaires, 1968, Volume: 35, Issue:3 Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Osteoporosis; Prednison	1968
[Bone biopsy studies in systemic lupus erythematosus treated with encortone]. Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 42, Issue:2 Topics: Adolescent; Adult; Biopsy; Bone and Bones; Female; Humans; Lupus Erythematosus, Systemic; Male; Oste	1969
[Side-effects of glucocorticoids in liver therapy]. Deutsche medizinische Wochenschrift (1946), 1969, Jun-27, Volume: 94, Issue:26 Topics: Acute Disease; Chronic Disease; Diabetes Mellitus; Fractures, Spontaneous; Glucocorticoids; Hepatiti	1969
[Chlorambucil in the treatment of idiopathic nephrotic syndrome without glomrular lesions in childhood. Apropos of 30 cases]. Annales de pediatrie, 1969, Jan-02, Volume: 16, Issue:1 Topics: Adolescent; Anemia; Biopsy; Child; Child, Preschool; Chlorambucil; Female; Glucocorticoids; Humans;	1969
[Bone changes due to prednisone addiction]. Zeitschrift fur arztliche Fortbildung, 1965, Nov-01, Volume: 59, Issue:21 Topics: Diagnosis, Differential; Female; Fractures, Spontaneous; Gastric Juice; Humans; Kidney Function Test	1965

prednisone and Osteoporosis