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triiodothyronine and Osteoporosis

triiodothyronine has been researched along with Osteoporosis in 27 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

ExcerptRelevanceReference
"To examine if triiodothyronine (T3) increases osteogenic differentiation adipose tissue derived stem cells (ASCs) from ovariectomized adult rats with osteoporosis compared with young rats and adult rats without osteoporosis."7.79[In vitro effects of triiodothyronine on the reduced osteogenic potential of adipose tissue derived mesenchymal stem cells from of ovariectomized rats and with osteoporosis]. ( Boeloni, JN; Goes, AM; Ocarino, NM; Serakides, R, 2013)
"To examine if triiodothyronine (T3) increases osteogenic differentiation adipose tissue derived stem cells (ASCs) from ovariectomized adult rats with osteoporosis compared with young rats and adult rats without osteoporosis."3.79[In vitro effects of triiodothyronine on the reduced osteogenic potential of adipose tissue derived mesenchymal stem cells from of ovariectomized rats and with osteoporosis]. ( Boeloni, JN; Goes, AM; Ocarino, NM; Serakides, R, 2013)
" Prolonged subclinical hyperthyroidism due to L-thyroxine treatment has been associated with reduced bone mass and thus with the potential risk of premature development of osteoporosis."3.70Bone mineral density in premenopausal women receiving levothyroxine suppressive therapy. ( Carpinelli, A; Del Puente, AE; Esposito Del Puente, A; Lupoli, G; Nuzzo, V; Oriente, P; Rampone, E, 1998)
"Myxedema coma (MC) is a rare, but often fatal endocrine emergency."1.37A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis. ( Chihara, K; Hino, Y; Iida, K; Ohara, T, 2011)
"Intense bone resorption is a natural phenomenon also observed in some teleosts, during reproductive migration and fasting."1.34Thyroid hormone-induced demineralisation of the vertebral skeleton of the eel, Anguilla anguilla. ( Aroua, S; Baloche, S; Dufour, S; Kacem, A; Lopez, E; Meunier, F; Rousseau, K; Sbaihi, M, 2007)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's7 (25.93)18.2507
2000's10 (37.04)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Deng, T1
Zhang, W1
Zhang, Y1
Zhang, M1
Huan, Z1
Yu, C1
Zhang, X1
Wang, Y2
Xu, J1
Boeloni, JN1
Ocarino, NM1
Goes, AM1
Serakides, R1
Acibucu, F1
Kilicli, F1
Dokmetas, HS1
Cardoso, LF1
Maciel, LM1
Paula, FJ1
Acar, B1
Ozay, AC1
Ozay, OE1
Okyay, E1
Sisman, AR1
Ozaksoy, D1
de Rougemont, A1
Mourot, MG1
Riou, JP1
Svare, A1
Nilsen, TI1
Bjøro, T1
Forsmo, S1
Schei, B1
Langhammer, A1
Iida, K1
Hino, Y1
Ohara, T1
Chihara, K1
Legroux-Gérot, I1
Vignau, J1
d'Herbomez, M1
Flipo, RM1
Cortet, B1
Chae, HJ2
Chae, SW1
Yun, DH2
Keum, KS1
Yoo, SK2
Kim, HR2
Chin, HY1
Kim, HM1
Kim, SB1
Biondi, B1
Palmieri, EA1
Klain, M1
Schlumberger, M1
Filetti, S1
Lombardi, G1
Bruni, V1
Dei, M1
Filicetti, MF1
Balzi, D1
Pasqua, A1
Sbaihi, M1
Kacem, A1
Aroua, S1
Baloche, S1
Rousseau, K1
Lopez, E1
Meunier, F1
Dufour, S1
Sampath, TK1
Simic, P1
Sendak, R1
Draca, N1
Bowe, AE1
O'Brien, S1
Schiavi, SC1
McPherson, JM1
Vukicevic, S1
Schlamp, D1
Schneider, P1
Krahl, A1
Trott, GE1
Warnke, A1
Marcocci, C1
Golia, F1
Bruno-Bossio, G1
Vignali, E1
Pinchera, A1
Földes, J1
Tarján, G1
Szathmari, M1
Varga, F1
Krasznai, I1
Horvath, C1
Wu, H1
Zhou, J1
Nuzzo, V1
Lupoli, G1
Esposito Del Puente, A1
Rampone, E1
Carpinelli, A1
Del Puente, AE1
Oriente, P1
Gruber, DM1
Huber, JC1
Aĭlamazian, EK1
Kornilov, NV1
Avrunin, AS1
Sukhanova, AM1
Zazerskaia, IE1
Al-Abadi, AC1
Ding, G1
Eckerström, S1
Raisz, LG1
Bingham, PJ1

Reviews

6 reviews available for triiodothyronine and Osteoporosis

ArticleYear
The multiple effects of thyroid disorders on bone and mineral metabolism.
    Arquivos brasileiros de endocrinologia e metabologia, 2014, Volume: 58, Issue:5

    Topics: Animals; Bone and Bones; Calcification, Physiologic; Calcium; Databases, Bibliographic; Epiphyses; H

2014
Subclinical hyperthyroidism: clinical features and treatment options.
    European journal of endocrinology, 2005, Volume: 152, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Cardiovascular Diseases; Female; Humans; Hyperthyroid

2005
Conjugated estrogens--the natural SERMs.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1999, Volume: 13 Suppl 6

    Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Cardiovascular Diseases; Dihydrotestosterone; Equilin;

1999
Subclinical thyrotoxicosis.
    Postgraduate medical journal, 2001, Volume: 77, Issue:903

    Topics: Cardiovascular Diseases; Diagnosis, Differential; Disease Progression; Humans; Hyperthyroidism; Oste

2001
[Hormone therapy in geriatrics].
    Lakartidningen, 1969, Jan-22, Volume: 66, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Androgens; Arteriosclerosis; Breast Neoplasms; Coronary Disease;

1969
Effect of hormones on bone development.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Adolescent; Aging; Animals; Ascorbic Acid; Bone Development; Calcitonin; Calcium; Collagen; Diphosph

1972

Trials

1 trial available for triiodothyronine and Osteoporosis

ArticleYear
Carefully monitored levothyroxine suppressive therapy is not associated with bone loss in premenopausal women.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:4

    Topics: Adult; Bone Density; Calcium; Dose-Response Relationship, Drug; Female; Goiter; Humans; Middle Aged;

1994

Other Studies

20 other studies available for triiodothyronine and Osteoporosis

ArticleYear
Thyroid-stimulating hormone decreases the risk of osteoporosis by regulating osteoblast proliferation and differentiation.
    BMC endocrine disorders, 2021, Mar-16, Volume: 21, Issue:1

    Topics: Adult; Animals; Animals, Newborn; Bone Density; Cell Differentiation; Cell Proliferation; Cells, Cul

2021
[In vitro effects of triiodothyronine on the reduced osteogenic potential of adipose tissue derived mesenchymal stem cells from of ovariectomized rats and with osteoporosis].
    Arquivos brasileiros de endocrinologia e metabologia, 2013, Volume: 57, Issue:2

    Topics: Adipose Tissue; Age Factors; Alkaline Phosphatase; Animals; Cell Differentiation; Female; Mesenchyma

2013
Assessment of bone mineral density in patients with Sheehan's syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:7

    Topics: Absorptiometry, Photon; Adrenocorticotropic Hormone; Bone Density; Case-Control Studies; Estradiol;

2014
Evaluation of thyroid function status among postmenopausal women with and without osteoporosis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 134, Issue:1

    Topics: Aged; Aged, 80 and over; Bone Density; Case-Control Studies; Female; Humans; Logistic Models; Lumbar

2016
Atypical thyrotropin-secreting pituitary microadenoma revealed by severe osteoporosis in a young man.
    Journal of bone and mineral metabolism, 2009, Volume: 27, Issue:4

    Topics: Adult; Alkaline Phosphatase; Body Height; Body Weight; Bone Density; Calcium; Carbimazole; Diphospho

2009
Hyperthyroid levels of TSH correlate with low bone mineral density: the HUNT 2 study.
    European journal of endocrinology, 2009, Volume: 161, Issue:5

    Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Cross-Sectional Studies; Female; Forearm; Humans;

2009
A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis.
    Endocrine journal, 2011, Volume: 58, Issue:2

    Topics: Autoantibodies; Carcinoembryonic Antigen; Cardiomegaly; Coma; Female; Hashimoto Disease; Human Growt

2011
Predictive factors of change in BMD at 1 and 2 years in women with anorexia nervosa: a study of 146 cases.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012, Volume: 23, Issue:12

    Topics: Absorptiometry, Photon; Adolescent; Adult; Alkaline Phosphatase; Anorexia Nervosa; Biomarkers; Bone

2012
Prevention of bone loss in ovariectomized rats: the effect of Salvia miltiorrhiza extracts.
    Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:1

    Topics: Alkaline Phosphatase; Animals; Calcium; Cell Count; Compressive Strength; Female; Femur; Osteoclasts

2004
Effect of dang-gui-ji-hwang-yeum on osteoporosis in ovariectomized rats.
    The American journal of Chinese medicine, 2004, Volume: 32, Issue:3

    Topics: Angelica sinensis; Animals; Drugs, Chinese Herbal; Female; Femur; Microscopy; Osteoblasts; Osteoclas

2004
Predictors of bone loss in young women with restrictive eating disorders.
    Pediatric endocrinology reviews : PER, 2006, Volume: 3 Suppl 1

    Topics: Adolescent; Adult; Amenorrhea; Body Composition; Body Mass Index; Bone Density; Dehydroepiandrostero

2006
Thyroid hormone-induced demineralisation of the vertebral skeleton of the eel, Anguilla anguilla.
    General and comparative endocrinology, 2007, Volume: 151, Issue:1

    Topics: Anguilla; Animals; Bone Demineralization, Pathologic; Bone Density; Bone Resorption; Female; Osteopo

2007
Thyroid-stimulating hormone restores bone volume, microarchitecture, and strength in aged ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:6

    Topics: Alkaline Phosphatase; Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Cell Different

2007
[Bone density in anorexia nervosa--with comments on prevention and therapy of osteoporosis].
    Zeitschrift fur Kinder- und Jugendpsychiatrie, 1994, Volume: 22, Issue:3

    Topics: Adolescent; Anorexia Nervosa; Body Weight; Bone Density; Child; Estradiol; Female; Follow-Up Studies

1994
Bone mineral density in patients with endogenous subclinical hyperthyroidism: is this thyroid status a risk factor for osteoporosis?
    Clinical endocrinology, 1993, Volume: 39, Issue:5

    Topics: Adult; Aged; Bone Density; Cross-Sectional Studies; Female; Femur Neck; Goiter, Nodular; Humans; Hyp

1993
[Post-thyroidectomy osteoporosis].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1996, Volume: 18, Issue:4

    Topics: Adult; Bone Density; Calcitonin; Carcinoma, Papillary; Female; Follow-Up Studies; Humans; Male; Midd

1996
Bone mineral density in premenopausal women receiving levothyroxine suppressive therapy.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1998, Volume: 12, Issue:5

    Topics: Adult; Body Mass Index; Bone Density; Female; Goiter; Humans; Hyperthyroidism; Linear Models; Middle

1998
[Diagnosis of short-term subclinical shifts in the level of humoral parameters].
    Klinicheskaia laboratornaia diagnostika, 2000, Issue:8

    Topics: Adult; Algorithms; Female; Hormones; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Models, The

2000
[Experimental study of thyroid hormone and bone metabolism in the rat].
    Zhonghua yi xue za zhi, 1990, Volume: 70, Issue:4

    Topics: Animals; Bone and Bones; Bone Density; Calcitonin; Female; Osteoporosis; Parathyroid Glands; Rats; T

1990
Letter: Replacement treatment of hypothyroidism.
    The New England journal of medicine, 1974, Jul-11, Volume: 291, Issue:2

    Topics: Female; Humans; Hyperthyroidism; Hypothyroidism; Menopause; Osteoporosis; Thyroid Hormones; Thyrotro

1974