estriol has been researched along with Osteoporosis in 39 studies
hormonin: estrogen replacement; each tablet contains 600 ug micronized 17beta-estradiol, 270 ug estriol and 1.4 mg estrone
chlorapatite : A phosphate mineral with the formula Ca5(PO4)3Cl.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-nine healthy women in the early menopause were assessed in terms of calcium metabolism, coronary risk factors, Kupperman index, and various serum hormones before and during replacement therapy with 17 beta-oestradiol plus oestriol and norethisterone acetate." | 9.05 | Does oestriol add to the beneficial effect of combined hormonal prophylaxis against early postmenopausal osteoporosis? ( Christiansen, C; Rødbro, P, 1984) |
| "Estriol has been described to be a weak and short-acting estrogen without an increased risk of endometrial proliferation and hyperplasia." | 6.69 | Estriol add-back therapy in the long-acting gonadotropin-releasing hormone agonist treatment of uterine leiomyomata. ( Ando, K; Kikuchi, A; Matsumi, H; Momoeda, M; Nakayama, H; Osuga, Y; Sagara, Y; Taketani, Y; Wang, Y; Watanabe, M; Yano, T, 1999) |
| "A randomized prospective controlled trial was performed in a cohort of 32 elderly Japanese women with osteoporosis receiving HRT (estriol plus medroxyprogesterone) for more than 1 year." | 5.15 | The effects of selective estrogen receptor modulator treatment following hormone replacement therapy on elderly postmenopausal women with osteoporosis. ( Hayashi, T; Ina, K; Maeda, M; Nomura, H, 2011) |
| "Sixty-nine healthy women in the early menopause were assessed in terms of calcium metabolism, coronary risk factors, Kupperman index, and various serum hormones before and during replacement therapy with 17 beta-oestradiol plus oestriol and norethisterone acetate." | 5.05 | Does oestriol add to the beneficial effect of combined hormonal prophylaxis against early postmenopausal osteoporosis? ( Christiansen, C; Rødbro, P, 1984) |
| " The treatment of nilestriol and levenorgestrel may decrease the bone turnover and correct the imbalance to cure the osteoporosis." | 3.71 | [Histomorphometric analysis in ovariectomized rat with osteoporosis]. ( Li, DQ; Wu, HW, 2001) |
| "Estriol has been described to be a weak and short-acting estrogen without an increased risk of endometrial proliferation and hyperplasia." | 2.69 | Estriol add-back therapy in the long-acting gonadotropin-releasing hormone agonist treatment of uterine leiomyomata. ( Ando, K; Kikuchi, A; Matsumi, H; Momoeda, M; Nakayama, H; Osuga, Y; Sagara, Y; Taketani, Y; Wang, Y; Watanabe, M; Yano, T, 1999) |
| " The results showed reduced levels of both estrogens in smokers as compared with nonsmokers in all three dosage groups." | 2.66 | Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. ( Christiansen, C; Jensen, J; Rødbro, P, 1985) |
| "25 micrograms, oestrogens/gestagen alone or combined with 1,25(OH)2D3, and placebo." | 2.65 | Effect of 1,25-dihydroxy-vitamin D3 in itself or combined with hormone treatment in preventing postmenopausal osteoporosis. ( Christensen, MS; Christiansen, C; Hagen, C; Rødbro, P; Transbøl, I, 1981) |
| " It is likely that a higher dosage would be more effective, but would cause the potential endometrial effects." | 2.65 | Bone loss during oestriol therapy in postmenopausal women. ( Clark, AC; Garwood, J; Hart, DM; Kraszewski, A; Lindsay, R; Maclean, A, 1979) |
| " A preliminary dose-response study performed in weanling rats determined 2000 microg/kg/day to be the optimal dose of 16alpha-OHE(1) for studying estrogenic effect on bone." | 1.32 | Comparative effects of long-term continuous release of 16 alpha-hydroxyestrone and 17 beta-estradiol on bone, uterus, and serum cholesterol in ovariectomized adult rats. ( Kennedy, AM; Lotinun, S; Turner, RT; Westerlind, KC, 2003) |
| "Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month." | 1.26 | The effects of therapy with oestriol succinate and ethinyl oestradiol on the haemostatic mechanism in post-menopausal women. ( Davies, T; Fieldhouse, G; McNicol, GP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (61.54) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gray, S | 1 |
| Dai, L | 1 |
| Wu, H | 1 |
| Yu, S | 1 |
| Zhao, H | 1 |
| Xue, L | 1 |
| Xu, M | 1 |
| Shen, Z | 1 |
| Hu, M | 1 |
| Zhang, ZQ | 2 |
| Liu, HY | 1 |
| Liu, XY | 1 |
| Hayashi, T | 1 |
| Ina, K | 1 |
| Maeda, M | 1 |
| Nomura, H | 1 |
| Song, B | 1 |
| Seifert-Klauss, V | 1 |
| Li, DQ | 1 |
| Wu, HW | 1 |
| Lotinun, S | 1 |
| Westerlind, KC | 1 |
| Kennedy, AM | 1 |
| Turner, RT | 1 |
| BORDIER, P | 1 |
| Jiang, G | 1 |
| Matsumoto, H | 1 |
| Yamane, J | 1 |
| Kuboyama, N | 1 |
| Akimoto, Y | 1 |
| Fujii, A | 1 |
| Riis, BJ | 2 |
| Christiansen, C | 9 |
| Rødbro, P | 6 |
| Tjellesen, L | 1 |
| Christensen, MS | 1 |
| Hagen, C | 1 |
| Transbøl, I | 2 |
| Utian, WH | 1 |
| Jensen, GF | 1 |
| MacMahon, B | 1 |
| Trichopoulos, D | 1 |
| Cole, P | 1 |
| Brown, J | 1 |
| Smetnik, VP | 2 |
| Holland, EF | 1 |
| Leather, AT | 1 |
| Studd, JW | 1 |
| Nakayama, H | 1 |
| Yano, T | 1 |
| Sagara, Y | 1 |
| Kikuchi, A | 1 |
| Ando, K | 1 |
| Wang, Y | 1 |
| Watanabe, M | 1 |
| Matsumi, H | 1 |
| Osuga, Y | 1 |
| Momoeda, M | 1 |
| Taketani, Y | 1 |
| Ishii, J | 1 |
| Lindsay, R | 1 |
| Hart, DM | 1 |
| Maclean, A | 1 |
| Garwood, J | 1 |
| Clark, AC | 1 |
| Kraszewski, A | 1 |
| Hempel, E | 1 |
| Kriester, A | 1 |
| Freesmeyer, E | 1 |
| Walter, W | 1 |
| Follingstad, AH | 1 |
| Toy, JL | 1 |
| Davies, JA | 1 |
| McNicol, GP | 2 |
| Yoshino, S | 1 |
| Kosaka, H | 1 |
| Saito, H | 1 |
| Kimura, S | 1 |
| Ogawa, K | 1 |
| Davies, T | 1 |
| Fieldhouse, G | 1 |
| Stagnaro, MN | 1 |
| Stagnaro, S | 1 |
| Nilas, L | 1 |
| Deftos, L | 1 |
| Göretzlehner, G | 1 |
| Kyank, H | 1 |
| Blum, M | 1 |
| Jensen, J | 1 |
| Möbius, W | 1 |
| Igarashi, M | 1 |
| Hayashi, Y | 1 |
| Karube, S | 1 |
| Plotz, EJ | 1 |
| Staemmler, HJ | 1 |
| Wille-Schörcher, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Trial of 13-cis Retinoic Acid (Isotretinoin) for the Treatment of Men With Oligoasthenoteratozoospermia[NCT02061384] | Phase 2 | 20 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Millions of sperm per ejaculate in men treated with 13-cis retinoic acid (NCT02061384)
Timeframe: Up to 20-weeks
| Intervention | Millions of sperm per ejaculate (Median) |
|---|---|
| 13-cis Retinoic Acid | 2.5 |
| Calcitriol 0.25 mcg | 3.8 |
2 reviews available for estriol and Osteoporosis
| Article | Year |
|---|---|
The place of oestriol therapy after menopause.
Topics: Aged; Breast Neoplasms; Costs and Cost Analysis; Estriol; Female; Humans; Menopause; Mental Disorder | 1980 |
[Comparative analyses on osteoporosis guidelines in Japan, EU and USA].
Topics: Alendronate; Calcitonin; Clinical Trials as Topic; Drug Approval; Estriol; Etidronic Acid; Europe; H | 2002 |
12 trials available for estriol and Osteoporosis
| Article | Year |
|---|---|
The effects of selective estrogen receptor modulator treatment following hormone replacement therapy on elderly postmenopausal women with osteoporosis.
Topics: Adiponectin; Aged; Blood Glucose; Bone Density; Cholesterol, HDL; Cholesterol, LDL; Estriol; Estroge | 2011 |
Does calcium potentiate the bone-preserving effect of oestrogen treatment in early post-menopausal women by a change in vitamin D metabolism?
Topics: Calcium; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Estradiol; Estriol; | 1984 |
Serum alkaline phosphatase during hormone treatment in early postmenopausal women. A model for establishing optimal prophylaxis and treatment in postmenopausal osteoporosis.
Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Clinical Trials as Topic; Estradiol; Estriol; Est | 1984 |
Does oestriol add to the beneficial effect of combined hormonal prophylaxis against early postmenopausal osteoporosis?
Topics: Calcium; Coronary Disease; Drug Therapy, Combination; Estradiol; Estriol; Female; Hormones; Humans; | 1984 |
Effect of 1,25-dihydroxy-vitamin D3 in itself or combined with hormone treatment in preventing postmenopausal osteoporosis.
Topics: Bone and Bones; Calcitriol; Calcium; Clinical Trials as Topic; Double-Blind Method; Drug Combination | 1981 |
Treatment of post menopausal osteoporosis. A controlled therapeutic trial comparing oestrogen/gestagen, 1,25-dihydroxy-vitamin D3 and calcium.
Topics: Aged; Bone and Bones; Calcitriol; Calcium; Clinical Trials as Topic; Double-Blind Method; Drug Combi | 1982 |
Increase in bone mass of older postmenopausal women with low mineral bone density after one year of percutaneous oestradiol implants.
Topics: Absorptiometry, Photon; Administration, Cutaneous; Aged; Bone Density; Drug Implants; Estriol; Estro | 1995 |
Estriol add-back therapy in the long-acting gonadotropin-releasing hormone agonist treatment of uterine leiomyomata.
Topics: Absorptiometry, Photon; Adult; Antineoplastic Agents, Hormonal; Bone Density; Delayed-Action Prepara | 1999 |
Bone loss during oestriol therapy in postmenopausal women.
Topics: Adult; Alkaline Phosphatase; Bone and Bones; Calcium; Clinical Trials as Topic; Creatine; Double-Bli | 1979 |
Uncoupling of bone formation and resorption by combined oestrogen and progestagen therapy in postmenopausal osteoporosis.
Topics: Bone Development; Bone Resorption; Clinical Trials as Topic; Double-Blind Method; Drug Administratio | 1985 |
Photon absorptiometry studies in osteoporosis.
Topics: Bone and Bones; Calcitriol; Calcium; Clinical Trials as Topic; Drug Combinations; Estradiol; Estriol | 1985 |
Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause.
Topics: Adult; Bone Resorption; Drug Combinations; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; M | 1985 |
25 other studies available for estriol and Osteoporosis
| Article | Year |
|---|---|
Practice observed.
Topics: Anemia, Pernicious; Contraceptives, Oral, Synthetic; Crohn Disease; Cystitis, Interstitial; Desogest | 2018 |
Effects of OsteoKing on osteoporotic rabbits.
Topics: Absorptiometry, Photon; Acid Phosphatase; Administration, Oral; Animals; Bone Density; Bone Density | 2015 |
[Mechanism of the influence of CCE3 on bone mineral element metabolism in ovariectomized rats].
Topics: Animals; Bone Density; Estriol; Female; Follicle Stimulating Hormone; Interleukin-6; Luteinizing Hor | 2009 |
[Effects of exercise and nilestriol on bone size and bone mass in ovariectomized rats].
Topics: Animals; Bone and Bones; Bone Density; Combined Modality Therapy; Estriol; Female; Osteoporosis; Ova | 2011 |
[Question of a Colleague. Can I still give advice to my wife about hormone replacement?].
Topics: Age Factors; Aged; Clinical Trials as Topic; Estradiol; Estriol; Estrogens, Conjugated (USP); Female | 2002 |
[Histomorphometric analysis in ovariectomized rat with osteoporosis].
Topics: Animals; Estriol; Female; Levonorgestrel; Osteoporosis; Ovariectomy; Progesterone Congeners; Quinest | 2001 |
Comparative effects of long-term continuous release of 16 alpha-hydroxyestrone and 17 beta-estradiol on bone, uterus, and serum cholesterol in ovariectomized adult rats.
Topics: Animals; Bone and Bones; Cholesterol; Delayed-Action Preparations; Estradiol; Estriol; Female; Hydro | 2003 |
[Treatment of 15 cases of osteoporosis by the combination of 3 delayed-action hormonal steroids].
Topics: Delayed-Action Preparations; Estriol; Humans; Osteoporosis; Progesterone; Steroids; Testosterone | 1963 |
Prevention of trabecular bone loss in the mandible of ovariectomized rats.
Topics: Animals; Bone Density; Calcitonin; Calcium, Dietary; Estriol; Etidronic Acid; Female; Germanium; Man | 2004 |
Does postmenopausal bone loss respond to estrogen replacement therapy independent of bone loss rate?
Topics: Aged; Bone and Bones; Drug Therapy, Combination; Estradiol; Estradiol Congeners; Estriol; Female; Fo | 1983 |
Cigarette smoking and urinary estrogens.
Topics: Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Menopause; Menstruation; M | 1982 |
[Principles of replacement hormone therapy in climacteric disorders].
Topics: Adult; Aged; Cardiovascular Diseases; Climacteric; Estradiol; Estriol; Estrogen Replacement Therapy; | 1995 |
[Principles of hormone replacement therapy in climacteric].
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Climacteric; Estradiol; Estriol; Estrogen Replacem | 1997 |
[A prospective trial on osteoporosis following bilateral ovariectomy with and without oestrogen replacement (author's transl)].
Topics: Adult; Body Height; Castration; Estriol; Female; Fingers; Humans; Middle Aged; Osteoporosis; Postope | 1979 |
Estriol, the forgotten estrogen?
Topics: Breast Neoplasms; Estriol; Female; Humans; Osteoporosis; Risk; United States; United States Food and | 1978 |
The effects of long-term therapy with oestriol succinate on the haemostatic mechanism in postmenopausal women.
Topics: Adult; Estriol; Female; Hemostasis; Humans; Menopause; Middle Aged; Osteoporosis; Plasminogen; Plate | 1978 |
[Management of osteoporosis. (I) Effects of estriol on rats on low calcium diet].
Topics: Animals; Bone and Bones; Calcium; Estriol; Female; Osteoporosis; Rats | 1976 |
The effects of therapy with oestriol succinate and ethinyl oestradiol on the haemostatic mechanism in post-menopausal women.
Topics: Blood Coagulation Factors; Estriol; Ethinyl Estradiol; Female; Fibrinolysis; Hemostasis; Humans; Men | 1976 |
[Early clinical diagnosis of osteoporosis using auscultatory percussion. Therapeutic monitoring].
Topics: Adult; Aged; Aged, 80 and over; Auscultation; Calcium; Estriol; Female; Humans; Male; Middle Aged; O | 1991 |
[Estrogen metabolism and hormone substitution in the climacteric].
Topics: Adult; Aged; Climacteric; Dose-Response Relationship, Drug; Drug Administration Schedule; Estradiol; | 1985 |
Benefits of vaginal estriol cream combined with clonidine HCL for menopausal syndrome treatment.
Topics: Cholesterol; Cholesterol, HDL; Clonidine; Drug Therapy, Combination; Estriol; Female; Glycated Hemog | 1985 |
[Current treatment of climacteric problems].
Topics: Androgens; Climacteric; Estradiol; Estriol; Female; Humans; Menopause; Middle Aged; Osteoporosis; Pr | 1974 |
Effect of estriol on bone collagen of rats with experimental osteoporosis.
Topics: Administration, Oral; Amino Acids; Animals; Bone and Bones; Bone Resorption; Calcium; Calcium, Dieta | 1974 |
[Estrogens in the woman's life].
Topics: Aging; Blood Pressure; Bone and Bones; Cervix Mucus; Coronary Disease; Embryo Implantation; Endometr | 1971 |
[Problems of sex steroid therapy in aging women].
Topics: Adult; Aged; Androgens; Dysautonomia, Familial; Estriol; Estrogens; Female; Humans; Menopause; Middl | 1966 |