| Assay ID | Title | Year | Journal | Article |
|---|
| AID270584 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 10 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID217303 | Inhibition of fibrinogen binding to immobilized vitronectin receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID165504 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-7 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID183997 | Compound tested for inhibition of Ach-induced vasorelaxation was determined in rat aortic strips | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID291679 | Increase in body weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID291684 | Effect on femur ash weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID1159174 | Inhibition of fibronectin binding to human alpha5beta1 integrin after 1 hr by ELISA | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID270586 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 0.1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID165502 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-5 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID1159172 | Inhibition of vitronectin binding to human alphaVbeta3 integrin after 2 hrs by ELISA | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID291687 | Effect on phosphorus level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID92541 | Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma | 1992 | Journal of medicinal chemistry, May-29, Volume: 35, Issue:11
| Cyclic RGD peptide analogues as antiplatelet antithrombotics. |
| AID165505 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-5 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID1159182 | Inhibition of alphavbeta3 integrin-mediated cell adhesion in HUVEC after 15 mins by matrigel assay | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID170337 | Effect on the wet thrombus weight in male wistar rat was determined(in vivo) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID223377 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by thrombin | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID373516 | Stability in presence of pepsin at 37 degC after 90 mins | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4
| Synthesis, evaluation and 3D QSAR analysis of novel estradiol-RGD octapeptide conjugates with oral anti-osteoporosis activity. |
| AID291692 | Effect on uterus weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID270583 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 0.1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID291686 | Effect on calcium level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID270587 | Decrease in weight of wet thrombus in rat at 5 umol/kg | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID165507 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-7 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID291685 | Effect on femur length in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID270585 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID270582 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID291689 | Effect on lung weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID291680 | Effect on serum ALP lavel in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID165503 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-6 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID73164 | Inhibition of fibrinogen binding to immobilized fibrinogen receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID270588 | Decrease in weight of dry thrombus in rat at 5 umol/kg | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID1159181 | Inhibition of alphavbeta3 integrin-mediated capillary tube formation in HUVEC after 16 hrs by matrigel assay | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID291691 | Effect on spleen weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID270581 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 10 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
| AID73158 | Inhibition of Fibrinogen receptor | 1992 | Journal of medicinal chemistry, May-29, Volume: 35, Issue:11
| Cyclic RGD peptide analogues as antiplatelet antithrombotics. |
| AID291682 | Effect on serum phosphorus level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID1159175 | Inhibition of fibrinogen binding to human alpha2b/beta3 integrin after 1 hr by ELISA | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID291690 | Effect on liver weight in ovariectomized mouse at 0.110 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID291688 | Effect on mineral content in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID291681 | Effect on serum calcium level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID73166 | Inhibition of Fibrinogen receptor binding | 1992 | Journal of medicinal chemistry, Dec-25, Volume: 35, Issue:26
| Potent inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Asp-carboxylate of RGDX mimetics and the platelet GP IIb-IIIa receptor. |
| AID223376 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by collagen | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID291683 | Effect on dry weight of femurs in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
| AID1159173 | Inhibition of vitronectin binding to human alphaVbeta5 integrin after 1 hr by ELISA | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID165506 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-6 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID160947 | Inhibition of platelet aggregation (PRP) | 1992 | Journal of medicinal chemistry, Dec-25, Volume: 35, Issue:26
| Potent inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Asp-carboxylate of RGDX mimetics and the platelet GP IIb-IIIa receptor. |
| AID1159176 | Selectivity ratio IC50 for human alpha2b/beta3 integrin to IC50 for human alphaVbeta3 integrin | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. |
| AID170332 | Effect on the dry thrombus weight in male wistar rat was determined(in vivo) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
| AID223375 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by adenosine 5'-diphosphate-(ADP) | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |