Page last updated: 2024-12-06

methylprednisolone 17-hemisuccinate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

methylprednisolone 17-hemisuccinate: Mesh term is for the 21-succinate; RN given refers to (6alpha,11beta)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID13105989
MeSH IDM0093098

Synonyms (2)

Synonym
methylprednisolone 17-hemisuccinate
FT-0672166

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The same parasitic burden provoked only a slight decrease in the elimination half-life of methylprednisolone alcohol when its hemisuccinate ester was administered."( Comparative incidence of experimental fascioliasis on corticosteroid pharmacokinetics in sheep.
Alvinerie, M; Galtier, P; Houin, G; Toutain, PL; Tufenkji, AE, 1989
)
0.28

Bioavailability

ExcerptReferenceRelevance
" When methylprednisolone (80 mg) was also taken by mouth, the relative bioavailability of the tablets was 99%."( Kinetics of methylprednisolone and its hemisuccinate ester.
Derendorf, H; Möllmann, H; Rehder, J; Rohdewald, P; Schmidt, EW, 1985
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (8.33%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (8.33%)4.05%
Observational0 (0.00%)0.25%
Other10 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]