Assay ID | Title | Year | Journal | Article |
AID223375 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by adenosine 5'-diphosphate-(ADP) | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
AID170337 | Effect on the wet thrombus weight in male wistar rat was determined(in vivo) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID165505 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-5 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID381992 | Inhibition of 10 uM adenosine diphosphate-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291690 | Effect on liver weight in ovariectomized mouse at 0.110 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID381983 | Nitric oxide radical scavenging activity in rat aortic strip assessed as inhibition of acetylcholine-induced vasorelaxation at 1 uM | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID270586 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 0.1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID291692 | Effect on uterus weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID165502 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-5 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID291691 | Effect on spleen weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID301634 | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 0.1 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID183997 | Compound tested for inhibition of Ach-induced vasorelaxation was determined in rat aortic strips | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID301635 | Antithrombotic effect in Wistar rat assessed as reduction in wet thrombus mass at 5 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID270585 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID291689 | Effect on lung weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID291688 | Effect on mineral content in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID381999 | Antithrombotic activity in Wistar rat assessed as wet thrombus weight at 5 umol/kg | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291682 | Effect on serum phosphorus level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID291685 | Effect on femur length in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID381993 | Inhibition of 1 uM adenosine diphosphate-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291686 | Effect on calcium level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID270587 | Decrease in weight of wet thrombus in rat at 5 umol/kg | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID381997 | Inhibition of 0.1 uM platelet activating factor-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291683 | Effect on dry weight of femurs in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID382240 | Nitric oxide radical scavenging activity in rat aortic strip assessed as inhibition of acetylcholine-induced vasorelaxation at 10 uM | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID270584 | Effect on PAF-induced platelet aggregation in rabbit platelet-rich plasma at 10 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID381996 | Inhibition of 1 uM platelet activating factor-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID382001 | Antithrombotic activity in Wistar rat assessed as wet thrombus weight at 5 umol/kg | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID270588 | Decrease in weight of dry thrombus in rat at 5 umol/kg | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID291684 | Effect on femur ash weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID270581 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 10 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID165506 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-6 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID301629 | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 10 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID381995 | Inhibition of 10 uM platelet activating factor-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291687 | Effect on phosphorus level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID301630 | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 1 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID170332 | Effect on the dry thrombus weight in male wistar rat was determined(in vivo) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID165507 | Maximum rate of PAF induced platelet aggregation was determined in rabbit blood at a dose of 10-7 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID223377 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by thrombin | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
AID291679 | Increase in body weight in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID223376 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by collagen | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
AID92690 | Ability to inhibit the aggregation of fixed human platelets | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Design of a new class of orally active fibrinogen receptor antagonists. |
AID270582 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID301636 | Antithrombotic effect in Wistar rat assessed as reduction in dry thrombus mass at 5 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID381984 | Nitric oxide radical scavenging activity in rat aortic strip assessed as inhibition of acetylcholine-induced vasorelaxation at 100 uM | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID291681 | Effect on serum calcium level in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID301633 | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 1 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID301631 | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 0.1 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
AID270583 | Effect on ADP-induced platelet aggregation in rabbit platelet-rich plasma at 0.1 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17
| Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates. |
AID381994 | Inhibition of 0.1 uM adenosine diphosphate-induced platelet aggregation in rabbit blood | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| A class of novel nitronyl nitroxide labeling basic and acidic amino acids: synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations. |
AID165504 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-7 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID165503 | Maximum rate of ADP induced platelet aggregation was determined in rabbit blood at a dose of 10-6 mol/L (in vitro) | 2003 | Bioorganic & medicinal chemistry letters, Nov-17, Volume: 13, Issue:22
| Synthesis and bioactivities of nitronyl nitroxide and RGD containing pseudopeptides. |
AID73164 | Inhibition of fibrinogen binding to immobilized fibrinogen receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
AID217303 | Inhibition of fibrinogen binding to immobilized vitronectin receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23
| Low molecular weight, non-peptide fibrinogen receptor antagonists. |
AID291680 | Effect on serum ALP lavel in ovariectomized mouse at 0.1103 mmol/kg, ip once daily for 4 weeks | 2007 | Journal of medicinal chemistry, Jul-12, Volume: 50, Issue:14
| Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates. |
AID301632 | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 10 umol/L | 2007 | Bioorganic & medicinal chemistry, Nov-15, Volume: 15, Issue:22
| Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |