cimetidine has been researched along with Psoriasis in 13 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the efficacy of cimetidine and chlorpheniramine alone and in combination in the treatment of psoriasis under the conditions of a randomised controlled double-blind study." | 9.05 | Cimetidine and chlorpheniramine in the treatment of psoriasis. ( Brendel, E; Goerz, G; Kurka, M; Merk, H; Runne, U; Schäfer, J, 1983) |
| "A 2-month, double-blind, placebo-controlled clinical trial was undertaken to evaluate the effectiveness of cimetidine in the treatment of chronic, plaque-type psoriasis." | 9.05 | Cimetidine versus placebo in the treatment of psoriasis. ( Cottenot, F; Wallach, D, 1982) |
| "We examined the efficacy of cimetidine and chlorpheniramine alone and in combination in the treatment of psoriasis under the conditions of a randomised controlled double-blind study." | 5.05 | Cimetidine and chlorpheniramine in the treatment of psoriasis. ( Brendel, E; Goerz, G; Kurka, M; Merk, H; Runne, U; Schäfer, J, 1983) |
| "A 2-month, double-blind, placebo-controlled clinical trial was undertaken to evaluate the effectiveness of cimetidine in the treatment of chronic, plaque-type psoriasis." | 5.05 | Cimetidine versus placebo in the treatment of psoriasis. ( Cottenot, F; Wallach, D, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merk, H | 1 |
| Goerz, G | 1 |
| Runne, U | 1 |
| Kurka, M | 1 |
| Schäfer, J | 1 |
| Brendel, E | 1 |
| Manger, BF | 1 |
| Stix, R | 1 |
| Beck, AL | 1 |
| Kalden, JR | 1 |
| Wallach, D | 2 |
| Cottenot, F | 2 |
| Ben-Ami, M | 1 |
| Haim, S | 1 |
| Gilhar, A | 1 |
| Friedman-Birnbaum, R | 1 |
| Long, PR | 1 |
| Miller, OF | 1 |
| Roy, IJ | 1 |
| Yates, VM | 1 |
| Kerr, RE | 1 |
| Stashower, ME | 1 |
| Yeager, JK | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Wagner, KF | 1 |
| Urrea, AA | 1 |
| Vélez, GM | 1 |
| Nogues, AE | 1 |
| Camarasa, JG | 1 |
| Giacosa, A | 1 |
| Farris, A | 1 |
| Cheli, R | 1 |
| Decazes, JM | 1 |
| Andersen, M | 1 |
3 trials available for cimetidine and Psoriasis
| Article | Year |
|---|---|
Cimetidine and chlorpheniramine in the treatment of psoriasis.
Topics: Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinati | 1983 |
Cimetidine versus placebo in the treatment of psoriasis.
Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Guanidines; Humans; Male; | 1982 |
Cimetidine and psoriasis.
Topics: Cimetidine; Double-Blind Method; Guanidines; Humans; Psoriasis | 1981 |
10 other studies available for cimetidine and Psoriasis
| Article | Year |
|---|---|
Cimetidine and psoriatic arthritis.
Topics: Arthritis; Cimetidine; Guanidines; Humans; Psoriasis | 1983 |
[Cimetidine in psoriasis].
Topics: Aged; Cimetidine; Guanidines; Humans; Immunity, Cellular; Male; Psoriasis | 1982 |
Treatment of psoriasis with cimetidine.
Topics: Cimetidine; Guanidines; Humans; Psoriasis | 1980 |
Cimetidine and thrombocytopenia.
Topics: Aged; Cimetidine; Guanidines; Humans; Male; Psoriasis; Thrombocytopenia | 1980 |
Cimetidine as therapy for treatment-resistant psoriasis in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cimetidine; Humans; Male; Psoriasis | 1993 |
Psoriasis in an HIV-positive patient treated with cimetidine.
Topics: Adult; Cimetidine; Disease Progression; Follow-Up Studies; HIV Infections; Humans; Male; Psoriasis; | 1995 |
Cimetidine and psoriasis.
Topics: Adult; Cimetidine; Duodenal Ulcer; Female; Guanidines; Humans; Psoriasis | 1978 |
Cimetidine and psoriasis.
Topics: Cimetidine; Drug Evaluation; Duodenal Ulcer; Female; Guanidines; Humans; Psoriasis | 1978 |
[Severe psoriasis spectacularly improved during treatment with cimetidine (author's transl)].
Topics: Aged; Cimetidine; Guanidines; Humans; Male; Psoriasis | 1979 |
[Exacerbation of psoriasis during treatment with H2 antagonists].
Topics: Aged; Cimetidine; Female; Histamine H2 Antagonists; Humans; Middle Aged; Psoriasis; Ranitidine | 1991 |