chlorambucil has been researched along with Psoriasis in 9 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "B-, T- and O-lymphocytes detected as EAC-, E- and non-rosette forming lymphocytes were investigated in venous blood in 49 patients with connective tissue diseases, psoriasis and chronic lymphogenous leukaemia (CLL) during treatment with either prednisone alone, prednisone and cytostatic agents or cytostatic agents alone." | 3.65 | Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases. ( Jonsson, V, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bontoux, D | 1 |
| Peltier, A | 1 |
| Brouilhet, H | 1 |
| Coste, F | 1 |
| Jonsson, V | 1 |
| Datskovskiĭ, BM | 1 |
| Masetkin, IP | 1 |
| Osnovina, NG | 1 |
| Clements, PJ | 1 |
| Davis, J | 1 |
| Nashel, DJ | 1 |
| Durepaire, R | 1 |
| Eisenmann, D | 1 |
| Grupper, C | 1 |
| Steinberg, AD | 1 |
| Forbes, IJ | 1 |
4 reviews available for chlorambucil and Psoriasis
| Article | Year |
|---|---|
Cytotoxic drugs: their clinical application to the rheumatic diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemica | 1986 |
Mechanisms of action and clinical applications of cytotoxic drugs in rheumatic disorders.
Topics: Arthritis, Reactive; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Collagen Diseases; Cyclophos | 1985 |
Cytotoxic drugs in treatment of nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlor | 1972 |
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; G | 1973 |
5 other studies available for chlorambucil and Psoriasis
| Article | Year |
|---|---|
[Treatment of rheumatoid polyarthritis by so-called immunosuppressive agents].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Chlorambucil; Female; Humans; Immunosuppressi | 1967 |
Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Azathioprine; B-Lymphocytes; Child; Chlorambucil; Co | 1975 |
[External use of cytostatics in psoriasis].
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Chlorambucil; Cyclophosphamide; Drug Evaluation; | 1975 |
[Malignant reticulosis with Sezary's cells and psoriasis].
Topics: Aged; Chlorambucil; Dermatitis, Exfoliative; Diagnosis, Differential; Edema; Foot Dermatoses; Hand D | 1971 |
The clinical use of immunosuppressive drugs.
Topics: Adrenal Cortex Hormones; Aged; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; | 1973 |