Page last updated: 2024-11-02

oxyphenbutazone and Psoriasis

oxyphenbutazone has been researched along with Psoriasis in 7 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"We describe two patients who developed generalized pustular psoriasis after taking phenylbutazone and oxyphenbutazone respectively, and discuss the possible pharmacological mechanism of this effect."7.66Generalized pustular psoriasis precipitated by phenylbutazone and oxyphenbutazone. ( Hargreaves, GK; Reshad, H; Vickers, CF, 1983)
"We describe two patients who developed generalized pustular psoriasis after taking phenylbutazone and oxyphenbutazone respectively, and discuss the possible pharmacological mechanism of this effect."3.66Generalized pustular psoriasis precipitated by phenylbutazone and oxyphenbutazone. ( Hargreaves, GK; Reshad, H; Vickers, CF, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SPERLING, IL1
Versteegh, MI1
Vijverberg, PL1
van Dijk, HA1
Reshad, H1
Hargreaves, GK1
Vickers, CF1
Ring, EF1
Roberts, ME1
Wright, V1
Hill, AG1
Mehra, AC1
Cosh, JA1
Heber, W1

Reviews

2 reviews available for oxyphenbutazone and Psoriasis

ArticleYear
Thermography and rheumatic diseases.
    Bibliotheca radiologica, 1975, Issue:6

    Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Body Temperature

1975
[Isomorphic response in psoriasis vulgaris. Review and observations].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1974, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Amputation, Surgical; Antifungal Agents; Child; Cicatrix; Female; Glucocort

1974

Other Studies

5 other studies available for oxyphenbutazone and Psoriasis

ArticleYear
3 YEARS' EXPERIENCE WITH OXYPHENBUTAZONE IN THE TREATMENT OF RHEUMATIC DISORDERS.
    Applied therapeutics, 1964, Volume: 6

    Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Geriatrics; Gout; Osteoarthritis; Oxyphenbutazone; Pso

1964
[Pancreas irritation caused by oxyphenbutazone (Tanderil)].
    Nederlands tijdschrift voor geneeskunde, 1983, Oct-15, Volume: 127, Issue:42

    Topics: Adult; Amylases; Arthritis; Female; Humans; Oxyphenbutazone; Pancreatitis; Psoriasis

1983
Generalized pustular psoriasis precipitated by phenylbutazone and oxyphenbutazone.
    The British journal of dermatology, 1983, Volume: 109, Issue:1

    Topics: Adult; Aged; Female; Humans; Oxyphenbutazone; Phenylbutazone; Psoriasis

1983
Psoriatic arthritis. Follow-up study.
    Annals of the rheumatic diseases, 1976, Volume: 35, Issue:3

    Topics: Adult; Age Factors; Aged; Agglutination Tests; Arthritis; Arthritis, Rheumatoid; Female; Follow-Up S

1976
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974