Compounds > o-4-nitrophenyl phenylphosphonate
Page last updated: 2024-12-08

o-4-nitrophenyl phenylphosphonate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

O-4-nitrophenyl phenylphosphonate: phosphonate ester substrate for nitrophenyl phosphatase; RN & N1 from CI Form Index; cpd not in Chemline 7/7/83 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID171562
SCHEMBL ID548572
MeSH IDM0081020

Synonyms (20)

Synonym
o-4-nitrophenyl phenylphosphonate
4-nitrophenyl phenylphosphonate
4-nitrophenyl phenylphosphonate, adenosine receptor agonist, 5'-nucleotide phosphodiesterase substrate
(4-nitrophenoxy)-phenylphosphinic acid
4-nitrophenyl hydrogen phenylphosphonate
pnppph
57072-35-2
phenylphosphonic acid, mono(4-nitrophenyl) ester
FT-0689435
AM20040738
phosphonic acid, p-phenyl-, mono(4-nitrophenyl) ester
S10703
AKOS015901310
5'-nucleotide phosphodiesterase substrate
SCHEMBL548572
DTXSID90205683
mfcd00057611
CS-0079207
PD044503
AKOS040756105

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The permethrin susceptibility of larvae was determined by a dose-response bioassay."( Enzymes-based resistant mechanism in pyrethroid resistant and susceptible Aedes aegypti strains from northern Thailand.
Lumjuan, N; Prapanthadara, LA; Somboon, P; Somwang, P; Suwan, W; Walton, C; Yanola, J, 2011)		0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (33.33)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.31

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.31 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.87 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.31)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (8.33%)4.05%
Observational0 (0.00%)0.25%
Other11 (91.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.		210aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
ciprofloxacin
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.		2.610aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
iodoacetic acid
Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.. iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.		1.9710haloacetic acid;
organoiodine compound		alkylating agent
piperonyl butoxide
[no description available]		2.0610benzodioxolespesticide synergist
phenylphosphonic acid
phenylphosphonic acid: RN given refers to parent cpd; NM same as N1		1.9510benzenes
manganese
Manganese: A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035). manganese(4+) : A manganese cation that is monoatomic and has a formal charge of +4.		1.9710elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
permethrin
hemoglobin Atlanta-Coventry: Leu replaced by Pro at beta75 and Leu deleted at beta141		2.0610cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
fluorodeoxyglucose f18
Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)		2102-deoxy-2-((18)F)fluoro-D-glucose;
2-deoxy-2-fluoro-aldehydo-D-glucose
2',3'-cyclic amp
2',3'-cyclic AMP: structure; ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE was see ADENOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC AMP to search ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93		2.03102',3'-cyclic purine nucleotideEscherichia coli metabolite
mevinphos
Mevinphos: An organophosphate cholinesterase inhibitor that is used as an insecticide.		210
pyrethrins
[no description available]		2.0610
nitrophenols
Nitrophenols: PHENOLS carrying nitro group substituents.		3.69100
ConditionIndicatedRelationship StrengthStudiesTrials
Organophosphorus Poisoning
[description not available]		0210
Anton Syndrome
[description not available]		0210
Organophosphate Poisoning
Poisoning due to exposure to ORGANOPHOSPHORUS COMPOUNDS, such as ORGANOPHOSPHATES; ORGANOTHIOPHOSPHATES; and ORGANOTHIOPHOSPHONATES.		0210
Innate Inflammatory Response
[description not available]		02.610
Palmoplantaris Pustulosis
[description not available]		02.610
Dermatoses
[description not available]		02.610
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.		02.610
Psoriasis
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.		02.610
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS.		02.610
Infections, Staphylococcal
[description not available]		02.610
Staphylococcal Infections
Infections with bacteria of the genus STAPHYLOCOCCUS.		02.610