indirubin has been researched along with Psoriasis in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, C; Lin, Y; Lu, X; Shen, D; Wang, H; Xie, F; Yang, J; Zhang, H | 1 |
| Feng, F; Fu, J; Han, X; Hu, X; Li, L; Li, P; Liu, C; Liu, X; Meng, Y; Peng, B; Qi, C; Wang, Y; Yang, D; Zheng, Y | 1 |
| Chen, X; He, X; Hou, Y; Jiang, W; Li, W; Liu, M; Shen, F; Su, L; Xu, Z; Zhang, H; Zhu, Y; Zou, C | 1 |
| Chen, YF; Liu, SG; Luo, GP; Qu, YB | 1 |
| Chen, Z; Di, T; Li, P; Liu, Y; Qi, C; Wang, Y; Xie, X; Zhao, J | 1 |
| Chi, CC; Huang, YH; Hui, RC; Lin, YK; See, LC | 1 |
| Koo, J; Sekhon, S | 1 |
| Bassukas, ID; Gaitanis, G; Magiatis, P; Velegraki, A | 1 |
| Lee, BH; Lin, YK | 1 |
| Dai, H; Hu, J; Li, C; Li, J; Tao, C; Wu, J; Xu, J; Xue, X | 1 |
| Madan, R; McDermott, L; Rupani, R; Siegel, D | 1 |
| Chen, HW; Leu, YL; Lin, YK; Pang, JH; Wang, CT; Yang, SH | 1 |
| Digiovanni, J; Miyoshi, K; Sano, S; Takaishi, M | 1 |
| Chang, YC; Huang, YH; Leu, YL; Lin, YK; See, LC; Shen, YM; Tsou, TC | 1 |
| Chen, TY; Hsieh, WL; Lin, YK; Pang, JH; Tsai, CN; Wang, TM | 1 |
| Sun, DT; Yuan, ZZ | 1 |
1 review(s) available for indirubin and Psoriasis
| Article | Year |
|---|---|
A Review of Indigo Naturalis as an Alternative Treatment for Nail Psoriasis.
Topics: Administration, Topical; Cell Proliferation; Cytokines; Drugs, Chinese Herbal; Epidermis; Humans; Indigofera; Indoles; Keratinocytes; Nail Diseases; Oils; Ointments; Phytotherapy; Psoriasis; Randomized Controlled Trials as Topic; Severity of Illness Index; Signal Transduction; Skin; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2016 |
2 trial(s) available for indirubin and Psoriasis
| Article | Year |
|---|---|
Comparison of indirubin concentrations in indigo naturalis ointment for psoriasis treatment: a randomized, double-blind, dosage-controlled trial.
Topics: Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Humans; Indoles; Male; Ointments; Psoriasis; Treatment Outcome | 2018 |
Comparison of refined and crude indigo naturalis ointment in treating psoriasis: randomized, observer-blind, controlled, intrapatient trial.
Topics: Adult; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Humans; Indoles; Male; Medication Adherence; Middle Aged; Ointments; Patient Acceptance of Health Care; Phytotherapy; Psoriasis; Single-Blind Method | 2012 |
13 other study(ies) available for indirubin and Psoriasis
| Article | Year |
|---|---|
Indirubin combined with umbilical cord mesenchymal stem cells to relieve psoriasis-like skin lesions in BALB/c mice.
Topics: Animals; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-17; Interleukin-23; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Psoriasis; Skin Diseases; Tumor Necrosis Factor-alpha; Umbilical Cord | 2022 |
CD44 targeted indirubin nanocrystal-loaded hyaluronic acid hydrogel for the treatment of psoriasis.
Topics: Animals; Hyaluronic Acid; Hydrogels; Mice; Nanoparticles; Psoriasis; Skin | 2023 |
Targeting upregulation of the immunosuppressive activity of MDSCs with indirubin as a novel strategy to alleviate psoriasis.
Topics: Animals; Humans; Immunosuppressive Agents; Mice; Myeloid-Derived Suppressor Cells; Psoriasis; Skin; Up-Regulation | 2023 |
Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; beta Catenin; Cell Cycle Checkpoints; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; Filaggrin Proteins; HaCaT Cells; Humans; Indoles; Psoriasis; Wnt Signaling Pathway | 2020 |
Indirubin attenuates IL-17A-induced CCL20 expression and production in keratinocytes through repressing TAK1 signaling pathway.
Topics: Animals; Cell Line; Chemokine CCL20; Humans; Indoles; Interleukin-17; Keratinocytes; Male; MAP Kinase Kinase Kinases; Mice, Inbred BALB C; Psoriasis; Signal Transduction; Transcriptome | 2021 |
Indirubin: a novel topical agent in the treatment of psoriasis.
Topics: Double-Blind Method; Drugs, Chinese Herbal; Humans; Indoles; Psoriasis | 2018 |
A traditional Chinese remedy points to a natural skin habitat: indirubin (indigo naturalis) for psoriasis and the Malassezia metabolome.
Topics: Double-Blind Method; Drugs, Chinese Herbal; Ecosystem; Humans; Indigo Carmine; Indoles; Malassezia; Metabolome; Psoriasis | 2018 |
Does Lindioil (indirubin) treatment affect the composition of Malassezia species on psoriatic skin?
Topics: Double-Blind Method; Drugs, Chinese Herbal; Humans; Indoles; Malassezia; Psoriasis; Skin | 2018 |
Indirubin attenuates mouse psoriasis-like skin lesion in a CD274-dependent manner: an achievement of RNA sequencing.
Topics: Adolescent; Adult; Aged; Animals; B7-H1 Antigen; CDC2 Protein Kinase; Disease Models, Animal; Epidermis; Female; Flow Cytometry; Gene Expression Regulation; Humans; Indoles; Interferon-gamma; Interleukin-17; Keratinocytes; Male; Mice; Middle Aged; Primary Cell Culture; Psoriasis; Sequence Analysis, RNA; Skin Abnormalities; Toll-Like Receptor 3; Toll-Like Receptor 4; Young Adult | 2018 |
Anti-psoriatic effects of indigo naturalis on the proliferation and differentiation of keratinocytes with indirubin as the active component.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Dermatologic Agents; Down-Regulation; Gene Expression; Humans; Indigo Carmine; Indigofera; Indoles; Keratinocytes; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Protein Precursors; Psoriasis | 2009 |
Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804.
Topics: Animals; Breast Neoplasms; Cell Proliferation; Female; Humans; Indoles; Keratinocytes; Male; Mice; Oximes; Prostatic Neoplasms; Psoriasis; Sequence Analysis, DNA; Signal Transduction; Skin; Up-Regulation | 2012 |
Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes.
Topics: cdc25 Phosphatases; Cell Proliferation; DNA, Complementary; Dose-Response Relationship, Drug; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Gene Expression Regulation; Humans; Indigo Carmine; Indoles; Keratinocytes; Oligonucleotide Array Sequence Analysis; Plant Extracts; Psoriasis; Skin; Time Factors; Transfection | 2012 |
[Clinical and ultrastructural study on psoriasis treated by indirubin].
Topics: Adolescent; Adult; Epidermis; Female; Humans; Indoles; Male; Middle Aged; Psoriasis; Skin | 1987 |