epsilon-(gamma-glutamyl)-lysine has been researched along with Psoriasis* in 1 studies
1 other study(ies) available for epsilon-(gamma-glutamyl)-lysine and Psoriasis
| Article | Year |
|---|---|
N1N8-bis(gamma-glutamyl)spermidine cross-linking in epidermal-cell envelopes. Comparison of cross-link levels in normal and psoriatic cell envelopes.
N1N8-Bis(gamma-glutamyl)spermidine was found in exhaustive proteolytic digests of isolated cell envelopes from human epidermis at levels comparable with those of epsilon-(gamma-glutamyl)lysine. Significantly higher than normal amounts of these compounds, particularly the bis(gamma-glutamyl)polyamine, were observed in envelopes from afflicted areas (scales) of psoriatic patients. These findings support the notions that N1N8-bis(gamma-glutamyl)spermidine, like epsilon-(gamma-glutamyl)lysine, functions in cell envelopes as an enzyme-generated protein cross-link and stabilizing force and that individuals with the chronic, recurrent skin disease, psoriasis, exhibit in involved epidermis abnormal cell-envelope-protein cross-linking. Topics: Amino Acids; Cross-Linking Reagents; Dipeptides; Epidermis; Humans; Molecular Structure; Polyamines; Psoriasis; Skin; Spermidine; Spermine | 1990 |