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dihydroxyphenylalanine and Psoriasis

dihydroxyphenylalanine has been researched along with Psoriasis in 13 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"5-S-Cysteinyldopa and dopa concentrations in serum were studied by high-performance liquid chromatography (HPLC) in patients with psoriasis treated by 8-methoxypsoralen and UVA light."3.665-S-Cysteinyldopa and dopa in serum during treatment with 8-methoxypsoralen and UVA light. ( Hansson, C; Rorsman, H; Rosengren, E; Tegner, E, 1981)
" In a blind histologic assessment using routine and L-dihydroxyphenylalanine (dopa)-incubated tissue sections, both PM and SM were lentigines."3.66The PUVA-induced pigmented macule: a lentiginous proliferation of large, sometimes cytologically atypical, melanocytes. ( Harrist, TJ; Momtaz-T, K; Rhodes, AR, 1983)
"The excretion of the specific melanocytic metabolite 5-S-cysteinyldopa was studied in patients with psoriasis treated by 8-methoxypsoralen and UVA light."3.665-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light. ( Agrup, G; Hansson, C; Rorsman, H; Rosengren, E; Tegner, E, 1978)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199013 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BroƩr, BA1
Hansson, C3
Rorsman, H3
Rosengren, E4
Tegner, E4
Agrup, G2
Rhodes, AR1
Harrist, TJ1
Momtaz-T, K1
Nimmo, JE1
Gawkrodger, DJ1
O'Docherty, CS1
Going, SM1
Percy-Robb, IW1
Hunter, JA1
Wirestrand, LE1
Aronsson, A1
Barbeau, A2
Giroux, JM2
Dubuc, R1
Devoitille, JM1
De la Brassinne, MF1
Dethier, A1
Couteaux-Dumont, C1
Marks, R1
Wells, GC1
Lewis, MB1

Reviews

1 review available for dihydroxyphenylalanine and Psoriasis

ArticleYear
Observations on PUVA treatment of psoriasis and on 5-S-cysteinyldopa after exposure to UV light.
    Acta dermato-venereologica. Supplementum, 1983, Volume: 107

    Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Photochemotherapy; Pressure; Psoriasis; PUVA Therapy;

1983

Other Studies

12 other studies available for dihydroxyphenylalanine and Psoriasis

ArticleYear
[Comparative evaluation of catecholamine and dopa content in dermatoses].
    Laboratornoe delo, 1980, Issue:4

    Topics: Adult; Catecholamines; Circadian Rhythm; Dihydroxyphenylalanine; Dopamine; Eczema; Epinephrine; Fema

1980
5-S-Cysteinyldopa and dopa in serum during treatment with 8-methoxypsoralen and UVA light.
    Acta dermato-venereologica, 1981, Volume: 61, Issue:3

    Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanocytes; Middle Aged;

1981
The effect of UVB light on serum concentrations of 5-S-cysteinyldopa.
    Acta dermato-venereologica, 1983, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanocytes; M

1983
The PUVA-induced pigmented macule: a lentiginous proliferation of large, sometimes cytologically atypical, melanocytes.
    Journal of the American Academy of Dermatology, 1983, Volume: 9, Issue:1

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Humans; Lentigo; Male; Melanocytes; Middle Aged; Photoc

1983
5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.
    The Journal of investigative dermatology, 1978, Volume: 70, Issue:1

    Topics: Adult; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanocytes; Methoxsalen; Middle

1978
Plasma 5-S-cysteinyldopa as an index of melanogenesis.
    The British journal of dermatology, 1988, Volume: 118, Issue:4

    Topics: Adult; Anthralin; Cysteinyldopa; Dihydroxyphenylalanine; Female; Hair Color; Humans; Male; Melanins;

1988
Urinary excretion of 6-hydroxy-5-methoxyindole-2-carboxylic acid and 5-S-cysteinyldopa during PUVA treatment.
    Photo-dermatology, 1985, Volume: 2, Issue:2

    Topics: Adult; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Indoles; Kinetics; Male; Middle Aged;

1985
Levadopa and psoriasis.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Dihydroxyphenylalanine; Female; Huma

1972
Levodopa and Ro 4-4602 in psoriasis.
    Lancet (London, England), 1972, Aug-12, Volume: 2, Issue:7772

    Topics: Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Dihydroxyph

1972
Levodopa in treatment of psoriasis.
    Lancet (London, England), 1973, Mar-17, Volume: 1, Issue:7803

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Psoriasis

1973
A histochemical profile of lichen simplex.
    The British journal of dermatology, 1973, Volume: 88, Issue:6

    Topics: Adenosine Triphosphatases; Adult; Basement Membrane; Biopsy; Dihydroxyphenylalanine; Female; Histocy

1973
A pilot study of levodopa in psoriasis.
    The Australasian journal of dermatology, 1973, Volume: 14, Issue:3

    Topics: Adult; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Pilot Projects; Psoriasis

1973