Page last updated: 2024-10-29

isoniazid and Psoriasis

isoniazid has been researched along with Psoriasis in 24 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
" Isoniazid is an antibiotic with high bactericidal effect on replicating mycobacteria and constitutes the most commonly prescribed treatment for latent tuberculosis infection."7.91Severe psoriasis entering remission after treatment for latent tuberculosis with isoniazid: Report of two cases. ( Giácaman-von der Weth, M; Hernández-Bel, P; Partarrieu-Mejías, F; Pérez-Ferriols, A, 2019)
" Objective The aim of this study was to present the follow-up results for Isoniazid (INH) chemoprophylaxis in patients with psoriasis receiving different biological therapies."7.83Isoniazid toxicity and TB development during biological therapy of patients with psoriasis in Colombia. ( Cataño, J; Morales, M, 2016)
"Isoniazid therapy was started with marked improvement of psoriatic lesions before biologic treatment could be initiated."5.40Improvement in severe psoriasis associated with isoniazid treatment. ( Brzezinski, P; Chiriac, A; Feldman, SR; Ferariu, D; Solovan, C, 2014)
"To evaluate the safety of isoniazid (INH) prophylaxis for newly identified latent tuberculosis infection (LTBI) in ustekinumab-treated patients with psoriasis."5.16The safety of ustekinumab treatment in patients with moderate-to-severe psoriasis and latent tuberculosis infection. ( Ho, V; Kato, T; Leonardi, C; Li, S; Shen, YK; Song, M; Szapary, P; Tsai, TF; Wasfi, Y, 2012)
" Isoniazid is an antibiotic with high bactericidal effect on replicating mycobacteria and constitutes the most commonly prescribed treatment for latent tuberculosis infection."3.91Severe psoriasis entering remission after treatment for latent tuberculosis with isoniazid: Report of two cases. ( Giácaman-von der Weth, M; Hernández-Bel, P; Partarrieu-Mejías, F; Pérez-Ferriols, A, 2019)
" Objective The aim of this study was to present the follow-up results for Isoniazid (INH) chemoprophylaxis in patients with psoriasis receiving different biological therapies."3.83Isoniazid toxicity and TB development during biological therapy of patients with psoriasis in Colombia. ( Cataño, J; Morales, M, 2016)
" Latent tuberculosis was diagnosed at baseline and the patient was treated with isoniazid for 9 months."3.76Etanercept in a patient with severe psoriasis and latent viral hepatic disease and latent tuberculosis. ( Ferguglia, G; Laria, G; Prestinari, F, 2010)
"Although rare, tuberculosis has been reported with biologic treatment against psoriasis in Japan, a tuberculosis medium-burden country."1.56Mycobacterium tuberculosis infection in psoriatic patients treated with biologics: Real-world data from 18 Japanese facilities. ( Furue, M; Hayashi, H; Higashi, Y; Hino, R; Imafuku, S; Kaneko, S; Kikuchi, S; Koike, Y; Matsuzaka, Y; Mitoma, C; Miyagi, T; Morizane, S; Nakahara, T; Nakamura, M; Nomura, H; Ohata, C; Ohyama, B; Okazaki, F; Sawada, Y; Sugita, K; Takahashi, K; Tsuruta, N; Yamaguchi, K; Yamaguchi, M; Yanase, T; Yonekura, K, 2020)
"Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs."1.46Management of long-term therapy with biological drugs in psoriatic patients with latent tuberculosis infection in real life setting. ( Conti, A; Galdo, G; Gisondi, P; Lasagni, C; Odorici, G; Pellacani, G; Piaserico, S, 2017)
"The reactivation of a latent tuberculosis infection is one of the possible major events that may occur during biologic therapies for inflammatory chronic diseases such as psoriasis."1.42Prevalence of latent tuberculosis infection in patients with moderate to severe psoriasis taking biologic therapies in a dermatologic private practice in Miami, Florida. ( Dehesa, L; Kerdel, F; Medina-Gil, C; Vega, A, 2015)
"Isoniazid therapy was started with marked improvement of psoriatic lesions before biologic treatment could be initiated."1.40Improvement in severe psoriasis associated with isoniazid treatment. ( Brzezinski, P; Chiriac, A; Feldman, SR; Ferariu, D; Solovan, C, 2014)
"Screening for latent tuberculosis infection (LTBI) is mandatory in patients with psoriasis prior to biological therapy."1.40Latent tuberculosis infection in patients with chronic plaque psoriasis who are candidates for biological therapy. ( Girolomoni, G; Gisondi, P; Lo Cascio, G; Pezzolo, E, 2014)
"A case of acute respiratory failure due to diaphragmatic weakness following adalimumab therapy for psoriasis is described."1.35Acute bilateral phrenic neuropathy following treatment with adalimumab. ( Alexopoulou, A; Antoniou, C; Archimandritis, A; Katsambas, A; Katsaounis, P; Kilidireas, K; Koskinas, J; Papageorgiou, C; Soultati, A, 2009)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's15 (62.50)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Megna, M1
Patruno, C1
Bongiorno, MR1
Gambardella, A1
Guarneri, C1
Foti, C1
Lembo, S1
Loconsole, F1
Fabbrocini, G1
Kaneko, S1
Tsuruta, N1
Yamaguchi, K1
Miyagi, T1
Takahashi, K1
Higashi, Y1
Morizane, S1
Nomura, H1
Yamaguchi, M1
Hino, R1
Sawada, Y1
Nakamura, M1
Ohyama, B1
Ohata, C1
Yonekura, K1
Hayashi, H1
Yanase, T1
Matsuzaka, Y1
Sugita, K1
Kikuchi, S1
Mitoma, C1
Nakahara, T1
Furue, M1
Okazaki, F1
Koike, Y1
Imafuku, S1
Machado, Á1
Abreu, M1
Torres, T1
Baççıoğlu, A1
Karabulut, AA1
Kalpaklıoğlu, AF1
Momose, M1
Asahina, A1
Hayashi, M1
Yanaba, K1
Umezawa, Y1
Nakagawa, H1
Conti, A1
Piaserico, S1
Gisondi, P2
Odorici, G1
Galdo, G1
Lasagni, C1
Pellacani, G1
Huang, TH1
Wei, YC1
Lan, CE1
Snast, I1
Bercovici, E1
Avni, T1
Shitenberg, D1
Hodak, E1
Pavlovsky, L1
Partarrieu-Mejías, F1
Hernández-Bel, P1
Giácaman-von der Weth, M1
Pérez-Ferriols, A1
Sánchez-Moya, AI2
Dauden, E2
Chiriac, A1
Ferariu, D1
Solovan, C1
Brzezinski, P1
Feldman, SR1
Pezzolo, E1
Lo Cascio, G1
Girolomoni, G1
Medina-Gil, C1
Dehesa, L1
Vega, A1
Kerdel, F1
Cataño, J1
Morales, M1
Alexopoulou, A1
Koskinas, J1
Soultati, A1
Katsaounis, P1
Kilidireas, K1
Papageorgiou, C1
Antoniou, C1
Katsambas, A1
Archimandritis, A1
Prestinari, F1
Ferguglia, G1
Laria, G1
Tsai, TF2
Ho, V1
Song, M2
Szapary, P1
Kato, T1
Wasfi, Y1
Li, S1
Shen, YK1
Leonardi, C1
Chiu, HY1
Chan, D1
Shear, NH1
Fernández López, E1
de Unamuno Pérez, P1
Kagramanova, AT1
Tishchenko, LD1
Rowe, E1
Meffert, H1
Wischnewsky, GG1
Fellner, MJ1

Reviews

1 review available for isoniazid and Psoriasis

ArticleYear
[New approach to the pathogenetic therapy of psoriasis].
    Vestnik dermatologii i venerologii, 1987, Issue:4

    Topics: Adult; Drug Evaluation; Humans; Isoniazid; Methods; Middle Aged; Polyamines; Psoriasis; Tablets

1987

Trials

2 trials available for isoniazid and Psoriasis

ArticleYear
Isoniazid therapy for latent tuberculosis in psoriasis patients receiving biological agents: is it safe and efficacious?
    International journal of dermatology, 2014, Volume: 53, Issue:3

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Female; Humans; Immunosuppressive A

2014
The safety of ustekinumab treatment in patients with moderate-to-severe psoriasis and latent tuberculosis infection.
    The British journal of dermatology, 2012, Volume: 167, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Case-Contro

2012

Other Studies

21 other studies available for isoniazid and Psoriasis

ArticleYear
Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection.
    The Journal of dermatological treatment, 2022, Volume: 33, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Humans; Isoniazid; Latent Tuberculosis; Psoriasis; Retrospective

2022
Mycobacterium tuberculosis infection in psoriatic patients treated with biologics: Real-world data from 18 Japanese facilities.
    The Journal of dermatology, 2020, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Biological Products; Child; Femal

2020
Safety of secukinumab in psoriasis patients with latent tuberculosis infection.
    European journal of dermatology : EJD, 2020, Dec-01, Volume: 30, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Contraindications, Drug; Dermatologi

2020
Erythema Multiforme-like Dermatitis Due to Isoniazid Hypersensitivity in a Patient With Psoriasis.
    Cutis, 2021, Volume: 107, Issue:4

    Topics: Dermatitis; Erythema Multiforme; Humans; Isoniazid; Psoriasis

2021
Biologic treatments for elderly patients with psoriasis.
    The Journal of dermatology, 2017, Volume: 44, Issue:9

    Topics: Adalimumab; Age Factors; Aged; Aged, 80 and over; Antitubercular Agents; Biological Products; Cerebr

2017
Management of long-term therapy with biological drugs in psoriatic patients with latent tuberculosis infection in real life setting.
    Dermatologic therapy, 2017, Volume: 30, Issue:5

    Topics: Aged; Antitubercular Agents; Biological Products; Dermatologic Agents; Female; Follow-Up Studies; Hu

2017
QuantiFERON®-TB Gold test conversion in a psoriatic patient with pleural tuberculosis one year after adalimumab treatment.
    The Kaohsiung journal of medical sciences, 2018, Volume: 34, Issue:3

    Topics: Adalimumab; Anti-Inflammatory Agents; Antitubercular Agents; Biopsy; Humans; Isoniazid; Male; Middle

2018
Tuberculosis Screening in Patients with Psoriasis Receiving Biologic Therapy: A Retrospective Cohort Study.
    Acta dermato-venereologica, 2018, Nov-05, Volume: 98, Issue:10

    Topics: Adult; Aged; Antitubercular Agents; Biological Products; Chemoprevention; Female; Humans; Isoniazid;

2018
Severe psoriasis entering remission after treatment for latent tuberculosis with isoniazid: Report of two cases.
    The Journal of dermatology, 2019, Volume: 46, Issue:9

    Topics: Aged; Antitubercular Agents; Female; Humans; Isoniazid; Latent Tuberculosis; Male; Middle Aged; Psor

2019
Improvement in severe psoriasis associated with isoniazid treatment.
    Dermatology online journal, 2014, May-16, Volume: 20, Issue:5

    Topics: Aged; Antitubercular Agents; Facial Dermatoses; Humans; Isoniazid; Male; Psoriasis; Tuberculosis

2014
Latent tuberculosis infection in patients with chronic plaque psoriasis who are candidates for biological therapy.
    The British journal of dermatology, 2014, Volume: 171, Issue:4

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Biolog

2014
Prevalence of latent tuberculosis infection in patients with moderate to severe psoriasis taking biologic therapies in a dermatologic private practice in Miami, Florida.
    International journal of dermatology, 2015, Volume: 54, Issue:7

    Topics: Adalimumab; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclon

2015
Isoniazid toxicity and TB development during biological therapy of patients with psoriasis in Colombia.
    The Journal of dermatological treatment, 2016, Volume: 27, Issue:5

    Topics: Adult; Aged; Antitubercular Agents; Colombia; Female; Humans; Immunosuppressive Agents; Isoniazid; L

2016
Acute bilateral phrenic neuropathy following treatment with adalimumab.
    Clinical rheumatology, 2009, Volume: 28, Issue:11

    Topics: Acute Disease; Adalimumab; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoc

2009
Etanercept in a patient with severe psoriasis and latent viral hepatic disease and latent tuberculosis.
    American journal of clinical dermatology, 2010, Volume: 11 Suppl 1

    Topics: Antitubercular Agents; Etanercept; Hepatitis B; Humans; Immunoglobulin G; Immunologic Factors; Isoni

2010
Incidence of tuberculosis infection in psoriatic patients on anti-TNF therapy: report of a case series with 144 patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2011, Volume: 25, Issue:6

    Topics: Adalimumab; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antibodies, Monocl

2011
A case of latent tuberculosis reactivation in a patient treated with ustekinumab without concomitant isoniazid chemoprophylaxis in the PEARL trial.
    The British journal of dermatology, 2013, Volume: 168, Issue:2

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Dermatologic Agents; Humans; Isoniaz

2013
'Is it safe?' Safety is a process, not a question.
    The British journal of dermatology, 2012, Volume: 167, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Female; Humans; Is

2012
[A case of excellent response to efalizumab. Experience in the University Hospital of Salamanca].
    Actas dermo-sifiliograficas, 2008, Volume: 99 Suppl 1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antitubercular Agents; Biological Product

2008
[Therapeutic trial with isonicotinic acid hydrazide in chronic stationary psoriasis].
    Dermatologische Monatschrift, 1985, Volume: 171, Issue:6

    Topics: Adult; Chronic Disease; Female; Humans; Isoniazid; Male; Middle Aged; Psoriasis

1985
[Adverse effects of isoniazid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1970, Volume: 21, Issue:7

    Topics: Desensitization, Immunologic; Diagnosis, Differential; Drug Hypersensitivity; Drug Tolerance; Exanth

1970