rolipram has been researched along with Psoriasis in 2 studies
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Psoriasis is a common, chronic inflammatory disease characterized by abnormal skin plaques, and the effectiveness of phosphodiesterase 4 (PDE4) inhibitor to lessen the symptoms of psoriasis has been proved." | 1.51 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent. ( Chen, W; Dong, G; Feng, C; Gu, Z; Li, H; Li, J; Li, M; Liu, H; Tang, W; Xu, Y; Zhang, R; Zhang, X; Zhu, F, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akama, T | 1 |
| Baker, SJ | 1 |
| Zhang, YK | 1 |
| Hernandez, V | 1 |
| Zhou, H | 1 |
| Sanders, V | 1 |
| Freund, Y | 1 |
| Kimura, R | 1 |
| Maples, KR | 1 |
| Plattner, JJ | 1 |
| Zhang, X | 1 |
| Dong, G | 1 |
| Li, H | 1 |
| Chen, W | 1 |
| Li, J | 1 |
| Feng, C | 1 |
| Gu, Z | 1 |
| Zhu, F | 1 |
| Zhang, R | 1 |
| Li, M | 1 |
| Tang, W | 1 |
| Liu, H | 1 |
| Xu, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study to Evaluate the Possible Efficacy and Safety of Roflumilast in Patients With Ulcerative Colitis.[NCT05684484] | Phase 4 | 52 participants (Anticipated) | Interventional | 2023-02-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for rolipram and Psoriasis
| Article | Year |
|---|---|
Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Boron Compounds; Bridged | 2009 |
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
Topics: Animals; Caco-2 Cells; Catalytic Domain; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; | 2019 |