beta-lapachone has been researched along with Psoriasis in 2 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, K | 2 |
| Sellmer, A | 1 |
| Wiegrebe, W | 1 |
| Reichstein, A | 1 |
| Vortherms, S | 1 |
| Bannwitz, S | 1 |
| Tentrop, J | 1 |
| Prinz, H | 1 |
2 other studies available for beta-lapachone and Psoriasis
| Article | Year |
|---|---|
Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cell Division; Cell Line; Humans; Kera | 1999 |
Synthesis and structure-activity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular genera
Topics: Cell Line; Cell Membrane; Cell Proliferation; Dermatologic Agents; Dicumarol; Furans; Humans; Kerati | 2012 |