indomethacin has been researched along with Psoriasis in 48 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty patients with psoriasis undergoing a standard Ingram regime were entered into a double-blind comparison of oral indomethacin and placebo." | 9.07 | The effect of oral indomethacin on psoriasis treated with the Ingram regime. ( Goodfield, MJ; Rowell, NR; Sheehan-Dare, RA, 1991) |
| "Topical 1% indomethacin had no effect on chronic stable plaque psoriasis in an open controlled study using subjective clinical scores nor in a randomised double-blind inert base controlled study using both subjective and objective measurements of lesional response; nor did it initiate or affect the development of psoriasis after cold injury." | 9.06 | Lack of effect of topical indomethacin on psoriasis. ( Green, CA; Shuster, S, 1987) |
| "In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxyl]-acetic acid (acemetacin, TV 1322, Rantudil¿) and indometacin were tested in 40 patients (15 male, 25 female) suffering from psoriatic arthritis in which, in a period of three weeks, the patients received 180 mg acemetacin or 150 mg indometacin daily in form of three equally divided doses." | 9.05 | [Controlled double blind study on the effectiveness and adverse effects of acemetacin and indomethacin in the treatment of psoriatic arthritis]. ( Lonauer, G; Wirth, W, 1980) |
| " indomethacin per day was carried out on 34 patients with psoriatic arthritis and 16 patients with Reiter's disease." | 9.04 | A comparative pilot study of azapropazone and indomethacin in the treatment of psoriatic arthritis and Reiter's disease. ( Lassus, A, 1976) |
| "Fifty patients with psoriasis undergoing a standard Ingram regime were entered into a double-blind comparison of oral indomethacin and placebo." | 5.07 | The effect of oral indomethacin on psoriasis treated with the Ingram regime. ( Goodfield, MJ; Rowell, NR; Sheehan-Dare, RA, 1991) |
| "Topical 1% indomethacin had no effect on chronic stable plaque psoriasis in an open controlled study using subjective clinical scores nor in a randomised double-blind inert base controlled study using both subjective and objective measurements of lesional response; nor did it initiate or affect the development of psoriasis after cold injury." | 5.06 | Lack of effect of topical indomethacin on psoriasis. ( Green, CA; Shuster, S, 1987) |
| "In a double-blind fashion, we compared the effect of topical application of 1% indomethacin cream or 1% meclofenamate cream with the effect of vehicle therapy alone in thirty patients with psoriasis." | 5.06 | Topical application of nonsteroidal anti-inflammatory drugs prevents vehicle-induced improvement of psoriasis. ( Ellis, CN; Fallon, JD; Kang, S; Vanderveen, EE; Voorhees, JJ, 1986) |
| "In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxyl]-acetic acid (acemetacin, TV 1322, Rantudil¿) and indometacin were tested in 40 patients (15 male, 25 female) suffering from psoriatic arthritis in which, in a period of three weeks, the patients received 180 mg acemetacin or 150 mg indometacin daily in form of three equally divided doses." | 5.05 | [Controlled double blind study on the effectiveness and adverse effects of acemetacin and indomethacin in the treatment of psoriatic arthritis]. ( Lonauer, G; Wirth, W, 1980) |
| " indomethacin per day was carried out on 34 patients with psoriatic arthritis and 16 patients with Reiter's disease." | 5.04 | A comparative pilot study of azapropazone and indomethacin in the treatment of psoriatic arthritis and Reiter's disease. ( Lassus, A, 1976) |
| "The aim of the reported series of experiments was to examine the possible role played by arachidonic acid (Aa) derivatives in monocyte aggregation in psoriasis." | 3.67 | Arachidonic acid and LTB4 enhance aggregation of psoriatic peripheral blood mononuclear leukocytes in vitro. ( Altomare, GF; Pigatto, PD; Polenghi, MM; Tadini, GL; Villa, S, 1987) |
| " In a comparison of two non-steroidal anti-inflammatory agents in this condition we attempted to overcome the difficulties by using a run-in period during which the dosage of one of the trial drugs was adjusted to suit the individual patient." | 2.65 | The run-in period in trial design: a comparison of two non-steroidal anti-inflammatory agents in psoriatic arthropathy. ( Bird, HA; Fowler, PD; Leatham, PA; Wright, V, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (85.42) | 18.7374 |
| 1990's | 5 (10.42) | 18.2507 |
| 2000's | 2 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizuashi, M | 1 |
| Kuramoto, Y | 1 |
| Aiba, S | 1 |
| Tagami, H | 1 |
| Kanda, N | 1 |
| Tani, K | 1 |
| Enomoto, U | 1 |
| Nakai, K | 1 |
| Watanabe, S | 1 |
| COSTE, F | 1 |
| DELBARRE, F | 1 |
| BRAUN, S | 1 |
| NASTORG, G | 1 |
| Kingston, T | 1 |
| Marks, R | 2 |
| Katayama, H | 2 |
| Kawada, A | 2 |
| Leatham, PA | 1 |
| Bird, HA | 1 |
| Wright, V | 1 |
| Fowler, PD | 1 |
| Tkach, JR | 1 |
| Lonauer, G | 1 |
| Wirth, W | 1 |
| Misch, K | 1 |
| Davies, M | 1 |
| Greaves, M | 1 |
| Coutts, A | 1 |
| Krogstad, AL | 1 |
| Swanbeck, G | 1 |
| Wallin, BG | 1 |
| Pons, JC | 1 |
| Nekhlyudov, L | 1 |
| Delfraissy, JF | 1 |
| Tong, DW | 1 |
| Walder, BK | 1 |
| Daniliv, LN | 1 |
| Vlcek, F | 3 |
| Heimstädt, P | 1 |
| Lassus, A | 1 |
| Moen, F | 1 |
| Sheehan-Dare, RA | 1 |
| Goodfield, MJ | 1 |
| Rowell, NR | 1 |
| Arnold, WP | 1 |
| van Hooijdonk, CA | 1 |
| Mier, PD | 1 |
| van de Kerkhof, PC | 1 |
| Kemény, L | 1 |
| Csató, M | 1 |
| Nyirádi, J | 1 |
| Gábor, M | 1 |
| Dobozy, A | 1 |
| Lazarova, AZ | 1 |
| Tsankov, NK | 1 |
| Zlatkov, NB | 1 |
| Pigatto, PD | 1 |
| Polenghi, MM | 1 |
| Altomare, GF | 1 |
| Tadini, GL | 1 |
| Villa, S | 1 |
| Volk, HD | 1 |
| Koyka, I | 1 |
| Goan, SR | 1 |
| Gruner, S | 1 |
| Fiebig, H | 1 |
| Sönnichsen, N | 1 |
| Diezel, W | 1 |
| Higgs, GA | 1 |
| Green, CA | 1 |
| Shuster, S | 1 |
| Samsonov, VA | 1 |
| Timoshin, GG | 1 |
| Starkov, IV | 1 |
| Powles, AV | 1 |
| Griffiths, CE | 1 |
| Seifert, MH | 1 |
| Fry, L | 1 |
| Burdeĭnyĭ, AP | 1 |
| Sigidin, IaA | 1 |
| Novoselova, TM | 1 |
| Shall, L | 1 |
| Knopf, B | 1 |
| Barta, U | 1 |
| Sendagorta, E | 1 |
| Allegue, F | 1 |
| Rocamora, A | 1 |
| Ledo, A | 1 |
| Ellis, CN | 1 |
| Fallon, JD | 1 |
| Kang, S | 1 |
| Vanderveen, EE | 1 |
| Voorhees, JJ | 1 |
| Hart, FD | 1 |
| Cosh, JA | 1 |
| Emmrich, R | 1 |
| Zbojanová, M | 2 |
| Trnavský, K | 2 |
| Korting, GW | 1 |
| Metz, J | 1 |
| Metz, G | 1 |
| Treske, U | 1 |
| Haberman, JD | 1 |
| Ehrlich, GE | 1 |
| Levenson, C | 1 |
| Perkins, ES | 1 |
| MacFaul, PA | 1 |
| Tauchnitz, D | 1 |
| Duck, HJ | 1 |
| Cappelli, E | 1 |
| Rollier, R | 1 |
| Markouch, T | 1 |
| Vivas, M | 1 |
| Kern, AB | 1 |
| Rothermich, NO | 1 |
1 review available for indomethacin and Psoriasis
| Article | Year |
|---|---|
[Psoriasis vulgaris. Internal therapy].
Topics: Arsenic; Bromine; Cortisone; Folic Acid Antagonists; Humans; Indomethacin; Methotrexate; Psoriasis; | 1966 |
12 trials available for indomethacin and Psoriasis
| Article | Year |
|---|---|
The run-in period in trial design: a comparison of two non-steroidal anti-inflammatory agents in psoriatic arthropathy.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Clinical Trials as Topic; Diclofenac; Double-Blind Metho | 1982 |
[Controlled double blind study on the effectiveness and adverse effects of acemetacin and indomethacin in the treatment of psoriatic arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Double-Blind Method; Female; Humans; Indoleacetic | 1980 |
Axon-reflex-mediated vasodilatation in the psoriatic plaque?
Topics: Adult; Anesthetics; Axons; Erythema; Female; Humans; Indomethacin; Male; Middle Aged; Prostaglandin | 1995 |
[Use of indomethacin in the treatment of psoriatic arthritis].
Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Aged; P | 1978 |
A comparative pilot study of azapropazone and indomethacin in the treatment of psoriatic arthritis and Reiter's disease.
Topics: Adult; Apazone; Arthritis; Arthritis, Reactive; Clinical Trials as Topic; Drug Evaluation; Female; H | 1976 |
The effect of oral indomethacin on psoriasis treated with the Ingram regime.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anthralin; Chronic Disease; Coal Tar; Double-Blind Me | 1991 |
Lack of effect of topical indomethacin on psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Clinical Trials as Topic; Cold Temperature; Double | 1987 |
Exacerbation of psoriasis by indomethacin.
Topics: Aged; Female; Humans; Indomethacin; Male; Middle Aged; Psoriasis | 1987 |
[Treatment of psoriatic arthritis with gold salts (chrysotherapy)].
Topics: Adult; Arthritis; Clinical Trials as Topic; Dimercaprol; Drug Therapy, Combination; Female; Gold; Hu | 1986 |
The effects of concomitant administration of oral indomethacin with topical dithranol treatment in psoriasis.
Topics: Adolescent; Adult; Anthralin; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle | 1987 |
Topical application of nonsteroidal anti-inflammatory drugs prevents vehicle-induced improvement of psoriasis.
Topics: Administration, Topical; Arachidonic Acids; Biotransformation; Double-Blind Method; Humans; Indometh | 1986 |
Indomethacin in the treatment of uveitis. A double-blind trial.
Topics: Adolescent; Arthritis, Reactive; Clinical Trials as Topic; Colitis, Ulcerative; Diabetes Complicatio | 1965 |
35 other studies available for indomethacin and Psoriasis
| Article | Year |
|---|---|
Juvenile localized annular pustular psoriasis developing severe exacerbation after topical indomethacin application.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Child; Humans; Indomethaci | 2009 |
The skin fungus-induced Th1- and Th2-related cytokine, chemokine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris.
Topics: Adult; Antigens, Fungal; Candida albicans; Case-Control Studies; Chemokine CCL22; Chemokine CXCL10; | 2002 |
[EFFECTS OF INDOMETHACIN IN 96 CASES OF RHEUMATIC DISEASES].
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Arthritis; Arthritis, | 1964 |
Irritant reactions to dithranol in normal subjects and psoriatic patients.
Topics: Anthracenes; Anthralin; Dose-Response Relationship, Drug; Erythema; Humans; Indomethacin; Irritants; | 1983 |
[Effects of indomethacin on psoriasis (author's transl)].
Topics: Adult; Female; Humans; Indomethacin; Male; Middle Aged; Psoriasis | 1980 |
Exacerbation of psoriasis induced by indomethacin.
Topics: Adult; Aged; Female; Humans; Indomethacin; Male; Middle Aged; Prostaglandins, Synthetic; Psoriasis | 1981 |
Indomethacin-induced hyperglycemia in psoriatic arthritis.
Topics: Adult; Arthritis; Humans; Hyperglycemia; Indomethacin; Male; Psoriasis | 1982 |
Pharmacological studies of anthralin erythema.
Topics: Anthracenes; Anthralin; Aspirin; Betamethasone Valerate; Chlorpheniramine; Erythema; Female; Humans; | 1981 |
The course of the SAPHO syndrome during pregnancy.
Topics: Acne Vulgaris; Adult; Female; Humans; Hyperostosis; Indomethacin; Osteitis; Pregnancy; Pregnancy Com | 1996 |
Widespread plaque psoriasis responsive to mycophenolate mofetil.
Topics: Adult; Arthritis, Psoriatic; Female; Humans; Immunosuppressive Agents; Indomethacin; Mycophenolic Ac | 1999 |
[Various therapeutic problems in arthritic psoriasis].
Topics: Arthritis, Infectious; Balneology; Humans; Indomethacin; Methotrexate; Photochemotherapy; Psoriasis | 1979 |
[A case of sterno-costo-clavicular hyperostosis].
Topics: Adult; Calcitonin; Diagnostic Errors; Humans; Indomethacin; Male; Osteitis Deformans; Osteomyelitis; | 1978 |
[Psoriatic arthropathy].
Topics: Arthritis; Humans; Indomethacin; Methotrexate; Naproxen; Phenylbutazone; Psoriasis | 1977 |
Induction of ornithine decarboxylase following sellotape stripping in normal and psoriatic skin.
Topics: Adolescent; Adult; Betamethasone; Enzyme Induction; Female; Humans; Indomethacin; Male; Middle Aged; | 1990 |
[The irritant effect of dithranol using capillary resistance measurement].
Topics: Adult; Anthralin; Clemastine; Drug Eruptions; Female; Humans; Indomethacin; Male; Middle Aged; Psori | 1989 |
Psoriasis induced by topically applied indomethacin.
Topics: Administration, Topical; Female; Humans; Indomethacin; Middle Aged; Psoriasis | 1989 |
Arachidonic acid and LTB4 enhance aggregation of psoriatic peripheral blood mononuclear leukocytes in vitro.
Topics: Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Aggregation; Female; Humans; In Vitr | 1987 |
Serum-mediated inhibition of the interferon-gamma-induced HLA-DR expression on monocytes in patients with psoriasis.
Topics: Antigens, Surface; Cells, Cultured; HLA-D Antigens; HLA-DR Antigens; Humans; Indomethacin; Interfero | 1986 |
Topical indomethacin and psoriasis.
Topics: Administration, Topical; Humans; Indomethacin; Psoriasis | 1988 |
[Indomethacin ointment in the treatment of various dermatoses].
Topics: Adult; Dermatitis; Female; Humans; Indomethacin; Male; Middle Aged; Ointments; Psoriasis | 1988 |
[Local effect of the nonsteroidal anti-inflammatory drug indomethacin on psoriasis].
Topics: Administration, Topical; Anthralin; Humans; Indomethacin; Psoriasis; Salicylates; Salicylic Acid | 1987 |
Generalized pustular psoriasis precipitated by diclofenac and indomethacin.
Topics: Adult; Diclofenac; Humans; Indomethacin; Male; Psoriasis | 1987 |
Ankylosing spondylitis.
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Arthritis, Juvenile; Arthritis, Reactive; Colitis, Ul | 1968 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
[Hydroxyproline excretion in urine in chronic connective tissue disease].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Collagen | 1970 |
[Current status in the treatment of psoriatric arthritis].
Topics: Arthritis; Balneology; Climate; Humans; Indomethacin; Psoriasis | 1974 |
[Indocid in the treatment of psoriatic arthritis].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Humans; Indomethacin; Psoriasis | 1974 |
[The treatment of severe types of Reiter's disease].
Topics: Adrenal Cortex Hormones; Adult; Ampicillin; Arthritis, Reactive; Azathioprine; Blood Transfusion; Di | 1971 |
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop | 1968 |
Thermography in rheumatic diseases.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoi | 1968 |
[Psoriatic arthritis and ankylopoietic spondylarthritis].
Topics: Adenoma; Adult; Arthritis; Cyclophosphamide; Diabetes Complications; Diagnosis, Differential; Humans | 1969 |
[Curative action of Indocid in a case of very grave arthropathic pustular psoriasis].
Topics: Female; Humans; Indomethacin; Joint Diseases; Middle Aged; Psoriasis | 1968 |
[Severe arthropathic and pustular psoriasis cleared up by methotrexate].
Topics: Adrenal Cortex Hormones; Adult; Arthritis; Candidiasis; Drug Synergism; Humans; Indomethacin; Male; | 1969 |
Indomethacin for psoriasis.
Topics: Adult; Aged; Female; Humans; Indomethacin; Male; Middle Aged; Psoriasis | 1966 |
An extended study of indomethacin. II. Clinical therapy.
Topics: Adolescent; Adult; Arthritis; Arthritis, Rheumatoid; Aspirin; Child; Female; Gout; Humans; Indometha | 1966 |