hydroxychloroquine has been researched along with Psoriasis in 37 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A review of the literature on the longterm use of methotrexate in patients with rheumatoid arthritis (RA) showed that many questions on protocol remain unanswered." | 8.77 | Longterm methotrexate therapy in rheumatoid arthritis: a review. ( Kremer, JM, 1985) |
| " A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported." | 7.69 | Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995) |
| "Hydroxychloroquine (HQ) is an antimalarial drug that is widely used in many autoimmune rheumatic diseases, mainly in systemic lupus erythematosus (SLE)." | 5.72 | A case of palmoplantar pustular psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Akkuzu, G; Bes, C; Karaalioğlu, B; Mutlu, MY; Özgür, DS; Yıldırım, F, 2022) |
| "Hydroxychloroquine was discontinued and the patient was started on methotrexate therapy that resulted in resolution of her rashes in a week." | 5.51 | Hydroxychloroquine-induced inverse psoriasis. ( Khakwani, Z; Murphy, FT; Ullah, A; Zeb, H, 2019) |
| "Hydroxychloroquine (HCQ) has been used to treat systemic lupus erythematosus (SLE) in Japan since 2015." | 5.51 | A case of generalized pustular psoriasis caused by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Hashimoto, Y; Kawazoe, M; Kusunoki, N; Nanki, T; Shikano, K; Shindo, E; Yamamoto, T, 2019) |
| "A review of the literature on the longterm use of methotrexate in patients with rheumatoid arthritis (RA) showed that many questions on protocol remain unanswered." | 4.77 | Longterm methotrexate therapy in rheumatoid arthritis: a review. ( Kremer, JM, 1985) |
| "To describe two patients that had induction and exacerbation of psoriasis due to the administration of hydroxychloroquine, to adapt pertinent literature on the pathophysiology of this side effect, to review psoriasis-triggered cases by newer, non-quinolinic antimalarials, and to propose malaria treatment and prophylaxis guidelines for psoriatic patients." | 3.80 | Synthetic antimalarial drugs and the triggering of psoriasis - do we need disease-specific guidelines for the management of patients with psoriasis at risk of malaria? ( Bassukas, ID; Gaitanis, G; Gravani, A; Zioga, A, 2014) |
| "Among patients with RA or psoriasis, the adjusted risk of DM was lower for individuals starting a TNF inhibitor or hydroxychloroquine compared with initiation of other nonbiologic DMARDs." | 3.77 | Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis. ( Canning, C; Garg, R; Liu, J; Massarotti, E; Schneeweiss, S; Solomon, DH, 2011) |
| " Consequently, hydroxychloroquine and topical glucocorticoids therapy were initiated with reported improvement in pruritus, erythema, and scale." | 3.74 | Chronic cutaneous lupus erythematosus in vitiligo. ( Bossenbroek, NM; Johnson, H; Meehan, SA; Pomeranz, MK; Robles, M; Rosenman, K, 2008) |
| " A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported." | 3.69 | Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995) |
| "A patient with psoriatic arthritis developed a peripheral neuropathy while taking hydroxychloroquine and naproxen." | 3.67 | Drug-induced peripheral neuropathy in a patient with psoriatic arthritis. ( Rothenberg, RJ; Sufit, RL, 1987) |
| "A patient who developed exfoliative erythroderma 11 days after the initiation of hydroxychloroquine treatment for psoriatic arthritis is presented." | 3.67 | Plaquenil-induced erythroderma. ( James, WD; Slagel, GA, 1985) |
| "Hydroxychloroquine (HQ) is an antimalarial drug that is widely used in many autoimmune rheumatic diseases, mainly in systemic lupus erythematosus (SLE)." | 1.72 | A case of palmoplantar pustular psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Akkuzu, G; Bes, C; Karaalioğlu, B; Mutlu, MY; Özgür, DS; Yıldırım, F, 2022) |
| "8% oral bioavailability in mice." | 1.56 | A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist. ( Bandopadhyay, P; Ganguly, D; Kundu, B; Mitra, M; Mukherjee, A; Paul, B; Raychaudhuri, D; Sinha, BP; Talukdar, A, 2020) |
| "Hydroxychloroquine was discontinued and the patient was started on methotrexate therapy that resulted in resolution of her rashes in a week." | 1.51 | Hydroxychloroquine-induced inverse psoriasis. ( Khakwani, Z; Murphy, FT; Ullah, A; Zeb, H, 2019) |
| "Hydroxychloroquine (HCQ) has been used to treat systemic lupus erythematosus (SLE) in Japan since 2015." | 1.51 | A case of generalized pustular psoriasis caused by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Hashimoto, Y; Kawazoe, M; Kusunoki, N; Nanki, T; Shikano, K; Shindo, E; Yamamoto, T, 2019) |
| "Psoriasis was diagnosed in 63 patients (49 females, 14 males) for a prevalence of 3." | 1.46 | Psoriasis in systemic lupus erythematosus: a single-center experience. ( Gladman, DD; Pakchotanon, R; Polachek, A; Su, J; Tselios, K; Urowitz, MB; Yap, KS, 2017) |
| "The association psoriasis and systemic lupus erythematosus (SLE) is a very uncommon association." | 1.32 | [Psoriasis and systemic lupus erythematosus: a rare association with specific therapeutic problems]. ( Arlet, P; Astudillo, L; Carreiro, M; Dahan, S; Ollier, S; Sailler, L, 2003) |
| "Acute pustular psoriasis is characterized by fiery-red erythema followed by formation of pustules." | 1.32 | Acute pustular psoriasis complicated by leukocytoclastic vasculitis. ( Welsch, MJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (21.62) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 10 (27.03) | 24.3611 |
| 2020's | 10 (27.03) | 2.80 |
| Authors | Studies |
|---|---|
| Mukherjee, A | 1 |
| Raychaudhuri, D | 1 |
| Sinha, BP | 1 |
| Kundu, B | 1 |
| Mitra, M | 1 |
| Paul, B | 1 |
| Bandopadhyay, P | 1 |
| Ganguly, D | 1 |
| Talukdar, A | 1 |
| Kishibe, M | 1 |
| Takeda, K | 1 |
| Honma, M | 1 |
| Makino, Y | 1 |
| Ishida-Yamamoto, A | 1 |
| Karaalioğlu, B | 1 |
| Yıldırım, F | 1 |
| Mutlu, MY | 1 |
| Akkuzu, G | 1 |
| Özgür, DS | 1 |
| Bes, C | 1 |
| Kutlu, Ö | 1 |
| Metin, A | 1 |
| Ozaras, R | 1 |
| Berk, A | 1 |
| Ucar, DH | 1 |
| Duman, H | 1 |
| Kaya, F | 1 |
| Mutlu, H | 1 |
| Sachdeva, M | 1 |
| Mufti, A | 1 |
| Maliyar, K | 1 |
| Lytvyn, Y | 1 |
| Yeung, J | 1 |
| Facheris, P | 1 |
| Valenti, M | 1 |
| Pavia, G | 1 |
| Gargiulo, L | 1 |
| Narcisi, A | 1 |
| Costanzo, A | 1 |
| Borroni, RG | 1 |
| Öncü, INS | 1 |
| Güler, D | 1 |
| Gürel, G | 1 |
| Midorikawa, H | 1 |
| Kiniwa, Y | 1 |
| Minagawa, A | 1 |
| Osawa, K | 1 |
| Shirai, T | 1 |
| Sano, T | 1 |
| Nakamura, K | 1 |
| Ashida, A | 1 |
| Ueno, KI | 1 |
| Takeichi, T | 1 |
| Akiyama, M | 1 |
| Okuyama, R | 1 |
| Rutlen, C | 1 |
| Blatt, P | 1 |
| Kim, T | 1 |
| Burnett, J | 1 |
| Wang, WM | 1 |
| Wang, KY | 1 |
| Wang, T | 1 |
| Jin, HZ | 1 |
| Fang, K | 1 |
| Ullah, A | 1 |
| Zeb, H | 1 |
| Khakwani, Z | 1 |
| Murphy, FT | 1 |
| Shindo, E | 1 |
| Shikano, K | 1 |
| Kawazoe, M | 1 |
| Yamamoto, T | 1 |
| Kusunoki, N | 1 |
| Hashimoto, Y | 1 |
| Nanki, T | 1 |
| Fisher, V | 1 |
| Fernandez, MP | 1 |
| Krejci-Manwaring, J | 1 |
| Gravani, A | 1 |
| Gaitanis, G | 1 |
| Zioga, A | 1 |
| Bassukas, ID | 1 |
| Ben Dhaou, B | 1 |
| Aydi, Z | 1 |
| Baili, L | 1 |
| Ketari, S | 1 |
| Boussema, F | 1 |
| Rokbani, L | 1 |
| Gupta, R | 1 |
| High, WA | 1 |
| Butler, D | 1 |
| Murase, JE | 1 |
| Tselios, K | 1 |
| Yap, KS | 1 |
| Pakchotanon, R | 1 |
| Polachek, A | 1 |
| Su, J | 1 |
| Urowitz, MB | 1 |
| Gladman, DD | 1 |
| Johnson, H | 1 |
| Bossenbroek, NM | 1 |
| Rosenman, K | 1 |
| Meehan, SA | 1 |
| Robles, M | 1 |
| Pomeranz, MK | 1 |
| Solomon, DH | 1 |
| Massarotti, E | 1 |
| Garg, R | 1 |
| Liu, J | 1 |
| Canning, C | 1 |
| Schneeweiss, S | 1 |
| Bongartz, T | 1 |
| Kudva, Y | 1 |
| Astudillo, L | 1 |
| Sailler, L | 1 |
| Carreiro, M | 1 |
| Dahan, S | 1 |
| Ollier, S | 1 |
| Arlet, P | 1 |
| Welsch, MJ | 1 |
| RUTLEDGE, WU | 1 |
| Sorbara, S | 1 |
| Cozzani, E | 1 |
| Rebora, A | 1 |
| Parodi, A | 1 |
| Trnavský, K | 1 |
| Zbojanová, M | 1 |
| Vlcek, F | 1 |
| Assier, H | 1 |
| Auffret, N | 1 |
| Beltzer-Garelly, E | 1 |
| Faures-Quenet, B | 1 |
| Binet, O | 1 |
| Vine, JE | 1 |
| Hymes, SR | 1 |
| Warner, NB | 1 |
| Cohen, PR | 1 |
| Sibilia, J | 1 |
| Cribier, B | 1 |
| Javier, RM | 1 |
| Pflumio, F | 1 |
| Kuntz, JL | 1 |
| Wolf, R | 2 |
| Schiavo, AL | 1 |
| Lombardi, ML | 1 |
| de Angelis, F | 1 |
| Ruocco, V | 2 |
| Ladanyi, E | 1 |
| Nagy, E | 1 |
| Rothenberg, RJ | 1 |
| Sufit, RL | 1 |
| Slagel, GA | 1 |
| James, WD | 1 |
| Friedman, SJ | 1 |
| Kremer, JM | 1 |
| Gray, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Rheumatoid Arthritis on Type 2 Diabetes Mellitus[NCT02639988] | 1,000 participants (Anticipated) | Observational | 2016-04-13 | Suspended | |||
| Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis: A Prospective Randomized Double Blind Controlled Study[NCT02644954] | Phase 3 | 40 participants (Anticipated) | Interventional | 2016-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydroxychloroquine and Psoriasis
| Article | Year |
|---|---|
Hydroxychloroquine effects on psoriasis: A systematic review and a cautionary note for COVID-19 treatment.
Topics: Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans | 2020 |
Triggered psoriasis.
Topics: Adrenergic beta-Antagonists; Antimalarials; Humans; Hydroxychloroquine; Lithium; Psoriasis; Transglu | 1999 |
Longterm methotrexate therapy in rheumatoid arthritis: a review.
Topics: Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Drug Resistance; Gold; Humans | 1985 |
34 other studies available for hydroxychloroquine and Psoriasis
| Article | Year |
|---|---|
A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist.
Topics: Animals; Binding Sites; Caco-2 Cells; Dermatologic Agents; HEK293 Cells; Humans; Male; Mice, Inbred | 2020 |
Effectiveness of anti-interleukin-17-receptor antibody for hydroxychloroquine-induced generalized pustular psoriasis in a patient with systemic lupus erythematosus.
Topics: Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Psoriasis; Receptors, Interleukin-17; Ski | 2022 |
A case of palmoplantar pustular psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
Topics: Antimalarials; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Psoriasis; Quality of Life | 2022 |
A case of exacerbation of psoriasis after oseltamivir and hydroxychloroquine in a patient with COVID-19: Will cases of psoriasis increase after COVID-19 pandemic?
Topics: Aged; Antiviral Agents; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Female; Humans; H | 2020 |
Covid-19 and exacerbation of psoriasis.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroqui | 2020 |
Complicated coronavirus disease 2019 (COVID-19) in a psoriatic patient treated with ixekizumab.
Topics: Antibodies, Monoclonal, Humanized; Betacoronavirus; Brugada Syndrome; Ceftriaxone; Clinical Laborato | 2020 |
Exacerbation of psoriasis following hydroxychloroquine in a patient with suspected COVID-19.
Topics: COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Psoriasis; SARS-CoV-2 | 2021 |
Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation.
Topics: Erythema; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Mutation; Psoriasis | 2021 |
A Worsening Rash.
Topics: Alcoholism; Antirheumatic Agents; Arthritis, Rheumatoid; Clobetasol; Diagnostic Errors; Glucocortico | 2022 |
Hydroxychloroquine-Induced Psoriasis-form Erythroderma in a Patient with Systemic Lupus Erythematosus.
Topics: Antirheumatic Agents; Dermatitis, Exfoliative; Humans; Hydroxychloroquine; Lupus Erythematosus, Syst | 2018 |
Hydroxychloroquine-induced inverse psoriasis.
Topics: Aged; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Psoriasis | 2019 |
A case of generalized pustular psoriasis caused by hydroxychloroquine in a patient with systemic lupus erythematosus.
Topics: Adult; Antirheumatic Agents; Arthralgia; Female; Humans; Hydroxychloroquine; Japan; Leukapheresis; L | 2019 |
Lichen planus mimicking recalcitrant ulcerative psoriasis: when is it time to biopsy?
Topics: Acitretin; Adult; Biopsy; Clobetasol; Dermatologic Agents; Female; Humans; Hydroxychloroquine; Liche | 2013 |
Synthetic antimalarial drugs and the triggering of psoriasis - do we need disease-specific guidelines for the management of patients with psoriasis at risk of malaria?
Topics: Adult; Antimalarials; Female; Humans; Hydroxychloroquine; Infant, Newborn; Malaria; Practice Guideli | 2014 |
Systemic lupus erythematosus and psoriasis: a new case.
Topics: Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Lupus Eryt | 2013 |
Medicolegal aspects of prescribing dermatological medications in pregnancy.
Topics: Acne Vulgaris; Alopecia; Dermatitis, Atopic; Dermatologic Agents; Dermatology; Female; Fetal Disease | 2013 |
Psoriasis in systemic lupus erythematosus: a single-center experience.
Topics: Adolescent; Adult; Antirheumatic Agents; Azathioprine; Cohort Studies; Female; Humans; Hydroxychloro | 2017 |
Chronic cutaneous lupus erythematosus in vitiligo.
Topics: Autoimmunity; Carcinoma, Squamous Cell; Clobetasol; Diabetes Complications; Diagnostic Errors; Drug | 2008 |
Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Cohort Studies; Diabetes Mellitus; Female | 2011 |
Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Cohort Studies; Diabetes Mellitus; Female | 2011 |
Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Cohort Studies; Diabetes Mellitus; Female | 2011 |
Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Cohort Studies; Diabetes Mellitus; Female | 2011 |
Can treatment of chronic inflammatory diseases reduce the risk of diabetes mellitus?
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Hu | 2011 |
[Psoriasis and systemic lupus erythematosus: a rare association with specific therapeutic problems].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Azathioprine; Dermatologic Agents; Femal | 2003 |
Acute pustular psoriasis complicated by leukocytoclastic vasculitis.
Topics: Acute Disease; Aged; Female; Humans; Hydroxychloroquine; Male; Prednisone; Psoriasis; Vasculitis, Le | 2003 |
WHAT'S NEW AND WHAT'S TRUE OF WHAT'S NEW IN DERMATOLOGY.
Topics: Amodiaquine; Dermatology; Humans; Hydroxychloroquine; Keratoacanthoma; Lupus Erythematosus, Discoid; | 1964 |
Hydroxychloroquine in psoriasis: is it really harmful?
Topics: Aged; Antimalarials; Arthralgia; Contraindications; Female; Humans; Hydroxychloroquine; Lupus Erythe | 2006 |
Antimalarials in psoriatic arthritis.
Topics: Adult; Aged; Arthritis; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Psoriasis | 1983 |
[Acute generalized exanthematous pustulosis induced by hydroxychloroquine].
Topics: Arthritis, Rheumatoid; Dermatitis, Exfoliative; Female; Humans; Hydroxychloroquine; Middle Aged; Pso | 1993 |
Pustular psoriasis induced by hydroxychloroquine: a case report and review of the literature.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Hydroxychloroquine; Methotrexate | 1996 |
Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine.
Topics: Female; Humans; Hydroxychloroquine; Middle Aged; Nail Diseases; Periostitis; Psoriasis; Recurrence; | 1995 |
The in vitro effect of hydroxychloroquine on skin morphology in psoriasis.
Topics: Antimalarials; Culture Techniques; Dermis; Epidermis; Humans; Hydroxychloroquine; Keratinocytes; Ker | 1999 |
[Simultaneous incidence of psoriasis and lupus erythematosus and their treatment].
Topics: Adult; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Male; Psoriasis | 1977 |
Drug-induced peripheral neuropathy in a patient with psoriatic arthritis.
Topics: Adult; Arthritis; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Naproxen; Neural Co | 1987 |
Plaquenil-induced erythroderma.
Topics: Adult; Arthritis; Dermatitis, Exfoliative; Female; Humans; Hydroxychloroquine; Psoriasis | 1985 |
Pustular psoriasis associated with hydroxychloroquine.
Topics: Humans; Hydroxychloroquine; Male; Middle Aged; Psoriasis | 1987 |
Hydroxychloroquine provocation of psoriasis.
Topics: Female; Humans; Hydroxychloroquine; Middle Aged; Psoriasis | 1985 |