clofazimine has been researched along with Psoriasis in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two cases of generalized pustular psoriasis (von Zumbusch) were successfully treated with clofazimine." | 7.66 | Treatment of pustular psoriasis with clofazimine. ( Chuaprapaisilp, T; Piamphongsant, T, 1978) |
| "Two cases of generalized pustular psoriasis (von Zumbusch) were successfully treated with clofazimine." | 3.66 | Treatment of pustular psoriasis with clofazimine. ( Chuaprapaisilp, T; Piamphongsant, T, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chuaprapaisilp, T | 1 |
| Piamphongsant, T | 1 |
| Nair, LV | 1 |
| Shereef, PH | 1 |
| Landow, RK | 1 |
1 review available for clofazimine and Psoriasis
| Article | Year |
|---|---|
New drugs for dermatologic diseases.
Topics: Clofazimine; Cyclosporins; Humans; Psoriasis; Sezary Syndrome; Skin Diseases | 1988 |
2 other studies available for clofazimine and Psoriasis
| Article | Year |
|---|---|
Treatment of pustular psoriasis with clofazimine.
Topics: Adult; Clofazimine; Coloring Agents; Humans; Male; Psoriasis | 1978 |
Successful treatment of generalized pustular psoriasis with clofazimine.
Topics: Clofazimine; Humans; Male; Middle Aged; Psoriasis | 1991 |