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clofazimine and Psoriasis

clofazimine has been researched along with Psoriasis in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Two cases of generalized pustular psoriasis (von Zumbusch) were successfully treated with clofazimine."7.66Treatment of pustular psoriasis with clofazimine. ( Chuaprapaisilp, T; Piamphongsant, T, 1978)
"Two cases of generalized pustular psoriasis (von Zumbusch) were successfully treated with clofazimine."3.66Treatment of pustular psoriasis with clofazimine. ( Chuaprapaisilp, T; Piamphongsant, T, 1978)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chuaprapaisilp, T1
Piamphongsant, T1
Nair, LV1
Shereef, PH1
Landow, RK1

Reviews

1 review available for clofazimine and Psoriasis

ArticleYear
New drugs for dermatologic diseases.
    Dermatologic clinics, 1988, Volume: 6, Issue:4

    Topics: Clofazimine; Cyclosporins; Humans; Psoriasis; Sezary Syndrome; Skin Diseases

1988

Other Studies

2 other studies available for clofazimine and Psoriasis

ArticleYear
Treatment of pustular psoriasis with clofazimine.
    The British journal of dermatology, 1978, Volume: 99, Issue:3

    Topics: Adult; Clofazimine; Coloring Agents; Humans; Male; Psoriasis

1978
Successful treatment of generalized pustular psoriasis with clofazimine.
    International journal of dermatology, 1991, Volume: 30, Issue:2

    Topics: Clofazimine; Humans; Male; Middle Aged; Psoriasis

1991