Page last updated: 2024-12-08

Rhododendrin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

rhododendrin: isolated from leaves of Rhododendron plants; has anti-inflammatory properties [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID442538
CHEMBL ID1086682
CHEBI ID8832

Synonyms (23)

Synonym
497-78-9
rhododendrin
C09965 ,
(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[(2r)-4-(4-hydroxyphenyl)butan-2-yl]oxyoxane-3,4,5-triol
AC1L9D1B ,
chebi:8832 ,
(-)-rhododendrin
CHEMBL1086682 ,
betuloside
.beta.-d-glucopyranoside, 3-(4-hydroxyphenyl)-1-methylpropyl, (r)-
.beta.-d-glucopyranoside, (1r)-3-(4-hydroxyphenyl)-1-methylpropyl
(1r)-3-(4-hydroxyphenyl)-1-methylpropyl .beta.-d-glucopyranoside
5i7qr8c454 ,
beta-d-glucopyranoside, (1r)-3-(4-hydroxyphenyl)-1-methylpropyl
unii-5i7qr8c454
rhododendrin, (-)-
beta-d-glucopyranoside, 3-(4-hydroxyphenyl)-1-methylpropyl, (r)-
rhododendrin [mi]
(1r)-3-(4-hydroxyphenyl)-1-methylpropyl beta-d-glucopyranoside
(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[(1r)-3-(4-hydroxyphenyl)-1-methyl-propoxy]tetrahydropyran-3,4,5-triol
Q7321115
DTXSID80964353
(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(((r)-4-(4-hydroxyphenyl)butan-2-yl)oxy)tetrahydro-2h-pyran-3,4,5-triol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
glycosideA glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID182348Compound was tested for hepatoprotective activity against D-GalN-induced cytotoxicity in primary cultured rat hepatocytes at 10 uM dose1998Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21
Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica.
AID480668Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as betahexosaminidase released at 100 uM after 20 mins by microplate reader assay2010Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
Inhibition of antigen-induced degranulation by aryl compounds isolated from the bark of Betula platyphylla in RBL-2H3 cells.
AID182350Compound was tested for hepatoprotective activity against D-GalN-induced cytotoxicity in primary cultured rat hepatocytes at 3 uM dose1998Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21
Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica.
AID480667Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as betahexosaminidase released at 10 uM after 20 mins by microplate reader assay2010Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
Inhibition of antigen-induced degranulation by aryl compounds isolated from the bark of Betula platyphylla in RBL-2H3 cells.
AID182351Compound was tested for hepatoprotective activity against D-GalN-induced cytotoxicity in primary cultured rat hepatocytes at 30 uM dose1998Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21
Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica.
AID182349Compound was tested for hepatoprotective activity against D-GalN-induced cytotoxicity in primary cultured rat hepatocytes at 100 uM dose1998Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21
Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 66.31

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index66.31 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index206.95 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (66.31)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]