Page last updated: 2024-11-08

serine and Psoriasis

serine has been researched along with Psoriasis in 17 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
" Here, we studied extracellular serine and serine/glycine metabolism using human keratinocytes, human skin biopsies, and a mouse model of psoriasis-like disease."8.12Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms. ( Albanesi, C; Annicchiarico-Petruzzelli, M; Belardo, A; Candi, E; Cappello, A; Cutruzzolà, F; Jia, W; Madonna, S; Mancini, M; Melino, G; Pallotta, S; Panatta, E; Paone, A; Rinaldo, S; Scarponi, C; Wang, L; Zolla, L; Zuccotti, A, 2022)
" Here, we studied extracellular serine and serine/glycine metabolism using human keratinocytes, human skin biopsies, and a mouse model of psoriasis-like disease."4.12Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms. ( Albanesi, C; Annicchiarico-Petruzzelli, M; Belardo, A; Candi, E; Cappello, A; Cutruzzolà, F; Jia, W; Madonna, S; Mancini, M; Melino, G; Pallotta, S; Panatta, E; Paone, A; Rinaldo, S; Scarponi, C; Wang, L; Zolla, L; Zuccotti, A, 2022)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's1 (5.88)18.2507
2000's0 (0.00)29.6817
2010's4 (23.53)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Su, S1
Katopodi, XL1
Pita-Juarez, YH1
Maverakis, E1
Vlachos, IS1
Adamopoulos, IE1
Cappello, A2
Mancini, M2
Madonna, S2
Rinaldo, S2
Paone, A2
Scarponi, C2
Belardo, A2
Zolla, L2
Zuccotti, A2
Panatta, E2
Pallotta, S2
Annicchiarico-Petruzzelli, M2
Albanesi, C2
Cutruzzolà, F2
Wang, L2
Jia, W2
Melino, G2
Candi, E2
Bowes, J1
Ashcroft, J1
Dand, N1
Jalali-Najafabadi, F1
Bellou, E1
Ho, P1
Marzo-Ortega, H1
Helliwell, PS1
Feletar, M1
Ryan, AW1
Kane, DJ1
Korendowych, E1
Simpson, MA1
Packham, J1
McManus, R1
Brown, MA1
Smith, CH1
Barker, JN1
McHugh, N1
FitzGerald, O1
Warren, RB1
Barton, A1
Andrés, RM1
Hald, A1
Johansen, C1
Kragballe, K1
Iversen, L1
Douroudis, K1
Kingo, K1
Silm, H1
Reimann, E1
Traks, T1
Vasar, E1
Kõks, S1
Chen, L1
Wu, J1
Pier, E1
Zhao, Y1
Shen, Z1
VOLKOV, VP1
Glinski, W2
Zarebska, Z2
Jabłonska, S2
Imiela, J2
Nosarzewski, J2
Chaplin, DD1
Zhou, Y1
Jarzabek-Chorzelska, M1
Neufahrt, A1
Förster, FJ1
Besser, H1
Balikcioglu, S1
Nowicki, L1
Behnken, L1
Grosshans, E1
Barbeau, A2
Giroux, JM2
Dubuc, R1
Schwarz, E2
Ellegaard, J1
Esmann, V1
Henriksen, L1
Kloss, G1
Slavík, M1
Hyánek, J1
Elis, J1
Homolka, J1

Reviews

1 review available for serine and Psoriasis

ArticleYear
Serine and arginine rich splicing factor 1 deficiency alters pathways involved in IL-17A expression and is implicated in human psoriasis.
    Clinical immunology (Orlando, Fla.), 2022, Volume: 240

    Topics: Alternative Splicing; Animals; Arginine; Humans; Interleukin-17; Mice; Psoriasis; RNA Splicing Facto

2022

Other Studies

16 other studies available for serine and Psoriasis

ArticleYear
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
    Science advances, 2022, 12-16, Volume: 8, Issue:50

    Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice;

2022
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
    Science advances, 2022, 12-16, Volume: 8, Issue:50

    Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice;

2022
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
    Science advances, 2022, 12-16, Volume: 8, Issue:50

    Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice;

2022
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
    Science advances, 2022, 12-16, Volume: 8, Issue:50

    Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice;

2022
Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Alleles; Arthritis, Psoriatic; Asparagine; Case-Control Studies; Ge

2017
Studies of Jak/STAT3 expression and signalling in psoriasis identifies STAT3-Ser727 phosphorylation as a modulator of transcriptional activity.
    Experimental dermatology, 2013, Volume: 22, Issue:5

    Topics: Biopsy; Gene Expression; Humans; Interleukin-6; Interleukins; Janus Kinase 1; Janus Kinase 2; Janus

2013
The CD226 Gly307Ser gene polymorphism is associated with severity of psoriasis.
    Journal of dermatological science, 2010, Volume: 58, Issue:2

    Topics: Adult; Age of Onset; Alleles; Antigens, Differentiation, T-Lymphocyte; Autoimmunity; Cohort Studies;

2010
mTORC2-PKBα/Akt1 Serine 473 phosphorylation axis is essential for regulation of FOXP3 Stability by chemokine CCL3 in psoriasis.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:2

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adult; Animals; CD4 Antigens; Cell Line, Transforme

2013
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
    Vestnik dermatologii i venerologii, 1964, Volume: 38

    Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multifor

1964
The activity of polymorphonuclear leukocyte neutral proteinases and their inhibitors in patients with psoriasis treated with a continuous peritoneal dialysis.
    The Journal of investigative dermatology, 1980, Volume: 75, Issue:6

    Topics: Endopeptidases; Humans; Neutrophils; Peritoneal Dialysis; Protease Inhibitors; Psoriasis; Serine

1980
HLA-linked skin disease: classical HLA genes or novel genes within HLA?
    The Journal of investigative dermatology, 1995, Volume: 104, Issue:5 Suppl

    Topics: Alleles; Epidermis; Genes, MHC Class I; HLA-C Antigens; Humans; Keratinocytes; Keratins; Membrane Gl

1995
Continuous peritoneal dialysis for treatment of psoriasis. II. Destruction of stratum corneum with peritoneal PMNL serine proteinase.
    Archives of dermatological research, 1979, Volume: 266, Issue:1

    Topics: Antigen-Antibody Complex; Endopeptidases; Humans; Neutrophils; Peritoneal Dialysis; Psoriasis; Serin

1979
[Isolation and amino acid composition of two pathologically augmented proteins from psoriatic scales (author's transl)].
    Archiv fur dermatologische Forschung, 1975, Jul-18, Volume: 252, Issue:4

    Topics: Alanine; Amino Acids; Electrophoresis, Disc; Galactosamine; Glycine; Humans; Leucine; Proteins; Psor

1975
Levadopa and psoriasis.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Dihydroxyphenylalanine; Female; Huma

1972
Levodopa and Ro 4-4602 in psoriasis.
    Lancet (London, England), 1972, Aug-12, Volume: 2, Issue:7772

    Topics: Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Dihydroxyph

1972
[Biochemistry of the epidermis].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Animals; Bony Callus; Carbon Isotopes; Histidine; Histocytochemistry; Humans; Mice; Molecular Weight

1972
Deficient folate activity during treatment of psoriasis with methotrexate diagnosed by determination of serine synthesis in lymphocytes.
    The British journal of dermatology, 1972, Volume: 87, Issue:3

    Topics: Adult; Aged; Carbon Isotopes; Female; Folic Acid Deficiency; Formates; Humans; In Vitro Techniques;

1972
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
    Archiv fur klinische und experimentelle Dermatologie, 1967, Volume: 228, Issue:2

    Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine;

1967
Typical hyperaminoaciduria after high doses of 6-azauridine triacetate.
    Biochemical pharmacology, 1969, Volume: 18, Issue:7

    Topics: Acetates; Adult; Alanine; Amino Acids; Chromatography, Paper; Glycine; Humans; Middle Aged; Psoriasi

1969