Page last updated: 2024-10-29

1-methyl-3-isobutylxanthine and Psoriasis

1-methyl-3-isobutylxanthine has been researched along with Psoriasis in 2 studies

1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eedy, DJ1
Canavan, JP1
Shaw, C1
Trimble, ER1
Iizuka, H1
Matsuo, S1
Tamura, T1
Ohkuma, N1

Other Studies

2 other studies available for 1-methyl-3-isobutylxanthine and Psoriasis

ArticleYear
Beta-adrenergic stimulation of cyclic AMP is defective in cultured dermal fibroblasts of psoriatic subjects.
    The British journal of dermatology, 1990, Volume: 122, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Cells, Cultured; Cyclic AMP; Female; Fibroblasts; Humans; Isopro

1990
Increased cholera toxin-, and forskolin-induced cyclic AMP accumulations in psoriatic involved versus uninvolved or normal human epidermis.
    The Journal of investigative dermatology, 1988, Volume: 91, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Humans; Male; P

1988