sulfasalazine has been researched along with Psoriasis in 24 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the efficacy of sulfasalazine and pentoxifylline, which have TNF antagonizing and anti-proliferative action in the treatment of psoriasis." | 9.15 | Sulfasalazine and pentoxifylline in psoriasis: a possible safe alternative. ( Abdel-Halim, M; Azzam, O; Bassiouny, DA; el-Darouti, M; el-Hadidi, H; el-Hanafy, G; el-Mofty, M; el-Ramly, A; Fawzy, M; Rasheed, H; Zaki, NS, 2011) |
| "In an 8-week double-blind trial of sulfasalazine for the treatment of moderate-to-severe psoriasis, 23 and 27 patients received the active and placebo tablets, respectively." | 9.06 | Sulfasalazine improves psoriasis. A double-blind analysis. ( Duell, EA; Ellis, CN; Griffiths, CE; Gupta, AK; Hamilton, TA; Nickoloff, BJ; Siegel, MT; Voorhees, JJ, 1990) |
| " He presented with (1) clinical features of HP, which resembled bullous pemphigoid; histopathological features of intraepidermal blisters, eosinophilic/neutrophilic spongiosis, and liquefactive degeneration of the basal cell layer; (3) positive anti-desmoglein 1 antibody by enzyme-linked immunosorbent assay and cell surface IgG reactivity within the epidermis by indirect immunofluorescence assay; and (4) a satisfactory response to salicylazosulfapyridine (sulfasalazine)." | 8.31 | A case of herpetiform pemphigus mimicking bullous pemphigoid after using secukinumab and successfully treated with sulfasalazine. ( Wang, M; Wang, R, 2023) |
| "In an open study, 32 patients with moderate to severe stable plaque psoriasis were treated with sulfasalazine, 3 gm daily for 8 weeks." | 7.67 | Sulfasalazine: a potential psoriasis therapy? ( Ellis, CN; Gupta, AK; Siegel, MT; Voorhees, JJ, 1989) |
| "To assess the efficacy of sulfasalazine and pentoxifylline, which have TNF antagonizing and anti-proliferative action in the treatment of psoriasis." | 5.15 | Sulfasalazine and pentoxifylline in psoriasis: a possible safe alternative. ( Abdel-Halim, M; Azzam, O; Bassiouny, DA; el-Darouti, M; el-Hadidi, H; el-Hanafy, G; el-Mofty, M; el-Ramly, A; Fawzy, M; Rasheed, H; Zaki, NS, 2011) |
| "In an 8-week double-blind trial of sulfasalazine for the treatment of moderate-to-severe psoriasis, 23 and 27 patients received the active and placebo tablets, respectively." | 5.06 | Sulfasalazine improves psoriasis. A double-blind analysis. ( Duell, EA; Ellis, CN; Griffiths, CE; Gupta, AK; Hamilton, TA; Nickoloff, BJ; Siegel, MT; Voorhees, JJ, 1990) |
| " He presented with (1) clinical features of HP, which resembled bullous pemphigoid; histopathological features of intraepidermal blisters, eosinophilic/neutrophilic spongiosis, and liquefactive degeneration of the basal cell layer; (3) positive anti-desmoglein 1 antibody by enzyme-linked immunosorbent assay and cell surface IgG reactivity within the epidermis by indirect immunofluorescence assay; and (4) a satisfactory response to salicylazosulfapyridine (sulfasalazine)." | 4.31 | A case of herpetiform pemphigus mimicking bullous pemphigoid after using secukinumab and successfully treated with sulfasalazine. ( Wang, M; Wang, R, 2023) |
| "In an open study, 32 patients with moderate to severe stable plaque psoriasis were treated with sulfasalazine, 3 gm daily for 8 weeks." | 3.67 | Sulfasalazine: a potential psoriasis therapy? ( Ellis, CN; Gupta, AK; Siegel, MT; Voorhees, JJ, 1989) |
| " Moreover, 1 drug should be used in appropriate dosage before it is assumed to be inefficient." | 1.28 | Ankylosing spondylitis. Current drug treatment. ( Gran, JT; Husby, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.50) | 18.7374 |
| 1990's | 12 (50.00) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, R | 1 |
| Wang, M | 1 |
| Kelly, JB | 1 |
| Foley, P | 1 |
| Strober, BE | 1 |
| Silva-Fernández, L | 1 |
| Pérez-Vicente, S | 1 |
| Martín-Martínez, MA | 1 |
| López-González, R | 1 |
| Romdhane, HB | 1 |
| Mokni, S | 1 |
| Fathallah, N | 1 |
| Slim, R | 1 |
| Ghariani, N | 1 |
| Sriha, B | 1 |
| Ben Salem, C | 1 |
| Braun, J | 1 |
| el-Mofty, M | 1 |
| el-Darouti, M | 1 |
| Rasheed, H | 1 |
| Bassiouny, DA | 1 |
| Abdel-Halim, M | 1 |
| Zaki, NS | 1 |
| el-Hanafy, G | 1 |
| el-Hadidi, H | 1 |
| Azzam, O | 1 |
| el-Ramly, A | 1 |
| Fawzy, M | 1 |
| Chen, LA | 1 |
| Su, LH | 1 |
| Chang, YJ | 1 |
| Hsu, YL | 1 |
| Tsai, TH | 1 |
| Castro Villegas, Mdel C | 1 |
| Escudero Contreras, A | 1 |
| Miranda García, MD | 1 |
| Collantes Estévez, E | 1 |
| Vaillant, L | 1 |
| Berson, M | 1 |
| Machet, L | 1 |
| Callens, A | 1 |
| Pourcelot, L | 1 |
| Lorette, G | 1 |
| McKenna, KE | 1 |
| Burrows, D | 1 |
| Marce, S | 1 |
| Schaeverbeke, T | 1 |
| Bannwarth, B | 1 |
| Marty, L | 1 |
| Dehais, J | 1 |
| Collange, C | 1 |
| Brantus, JF | 1 |
| Sidot, C | 1 |
| Meunier, PJ | 1 |
| Zivony, D | 1 |
| Nocton, J | 1 |
| Wortmann, D | 1 |
| Esterly, N | 1 |
| Dosik, JS | 1 |
| Gran, JT | 1 |
| Husby, G | 1 |
| Bodokh, I | 1 |
| Lacour, JP | 1 |
| Perrin, C | 1 |
| Gallais, V | 1 |
| Ortonne, JP | 1 |
| Bliddal, H | 1 |
| Stangerup, M | 1 |
| Gupta, AK | 2 |
| Ellis, CN | 2 |
| Siegel, MT | 2 |
| Duell, EA | 1 |
| Griffiths, CE | 1 |
| Hamilton, TA | 1 |
| Nickoloff, BJ | 1 |
| Voorhees, JJ | 2 |
| Farr, M | 2 |
| Kitas, GD | 2 |
| Waterhouse, L | 2 |
| Jubb, R | 2 |
| Felix-Davies, D | 2 |
| Bacon, PA | 2 |
| Halasz, CL | 1 |
| Seideman, P | 1 |
| Pears, JS | 1 |
| Morley, KD | 1 |
4 reviews available for sulfasalazine and Psoriasis
| Article | Year |
|---|---|
Current and future oral systemic therapies for psoriasis.
Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Cyclosporine; Fumarates; Humans | 2015 |
New targets in psoriatic arthritis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthrit | 2016 |
New-onset psoriasis associated with etanercept therapy.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Humans; Immunoglobulin G; Isoxazoles | 2010 |
[How to optimize the antiTNF alpha therapy in spondylitis?].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheu | 2012 |
4 trials available for sulfasalazine and Psoriasis
| Article | Year |
|---|---|
Sulfasalazine and pentoxifylline in psoriasis: a possible safe alternative.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; | 2011 |
Sulfasalazine improves psoriasis. A double-blind analysis.
Topics: Adult; Body Surface Area; Clinical Trials as Topic; Double-Blind Method; Eicosanoids; Female; Humans | 1990 |
Sulphasalazine in psoriatic arthritis: a double-blind placebo-controlled study.
Topics: Arthritis; Clinical Trials as Topic; Double-Blind Method; Humans; Immunoglobulins; Joints; Pain; Pla | 1990 |
Treatment of psoriatic arthritis with sulphasalazine: a one year open study.
Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Middle Aged; | 1988 |
16 other studies available for sulfasalazine and Psoriasis
| Article | Year |
|---|---|
A case of herpetiform pemphigus mimicking bullous pemphigoid after using secukinumab and successfully treated with sulfasalazine.
Topics: Adult; Humans; Male; Pemphigoid, Bullous; Pemphigus; Psoriasis; Sulfasalazine | 2023 |
Variability in the prescription of non-biologic disease-modifying antirheumatic drugs for the treatment of spondyloarthritis in Spain.
Topics: Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Cyclospo | 2015 |
Sulfasalazine-induced Sweet's syndrome.
Topics: Dermatologic Agents; Humans; Male; Middle Aged; Psoriasis; Sulfasalazine; Sweet Syndrome | 2016 |
Ultrasound imaging of psoriatic skin: a noninvasive technique to evaluate treatment of psoriasis.
Topics: Adult; Aged; Cell Division; Cyclosporine; Drug Combinations; Epidermis; Female; Follow-Up Studies; G | 1994 |
Leucopenia, thrombocytopenia and lymphadenopathy associated with sulphasalazine.
Topics: Adult; Female; Humans; Leukopenia; Lymphatic Diseases; Psoriasis; Sulfasalazine; Thrombocytopenia | 1994 |
[Generalized acute exanthematous pustulosis after ingestion of sulfasalazine].
Topics: Acute Disease; Dermatitis, Exfoliative; Drug Eruptions; Humans; Male; Middle Aged; Psoriasis; Sulfas | 1993 |
Sapho syndrome with femoral hyperostosis. Two case-reports.
Topics: Adult; Antirheumatic Agents; Diphosphonates; Female; Femur; Humans; Hyperostosis; Magnetic Resonance | 1996 |
Juvenile Reiter's syndrome: a report of four cases.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, | 1998 |
Psoriatic onycho-pachydermo-periostitis.
Topics: Biopsy; Face; Humans; Male; Methotrexate; Middle Aged; Osteoarthropathy, Primary Hypertrophic; Penis | 2001 |
Ankylosing spondylitis. Current drug treatment.
Topics: Adrenal Cortex Hormones; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Infla | 1992 |
[Hazards of treatment of psoriasis with sulfasalozine].
Topics: Acute Disease; Exanthema; Humans; Male; Middle Aged; Psoriasis; Risk Factors; Sulfasalazine | 1992 |
Psoriasis-like skin reaction in a patient with rheumatoid arthritis after sulphasalazine therapy.
Topics: Aged; Arthritis, Rheumatoid; Female; Hand Dermatoses; Humans; Psoriasis; Sulfasalazine | 1991 |
Sulfasalazine as folic acid inhibitor in psoriasis.
Topics: Folic Acid; Folic Acid Antagonists; Humans; Psoriasis; Sulfasalazine | 1990 |
Sulphasalazine treatment of psoriatic arthritis.
Topics: Arthritis; Humans; Psoriasis; Sulfasalazine | 1990 |
Sulfasalazine: a potential psoriasis therapy?
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Psoriasis; Sulfasalazine | 1989 |
Fatal hypersensitivity reaction to sulphasalazine.
Topics: Arthritis; Drug Hypersensitivity; Female; Humans; Middle Aged; Psoriasis; Sulfasalazine | 1989 |