metronidazole has been researched along with Psoriasis in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He had been receiving methotrexate (MTX) since boyhood for severe psoriasis." | 7.75 | [Prolonged fever and monocytosis after hemorrhoidectomy and treatment with methotrexate--listeriosis with cerebral abscess]. ( Krämer, S; Maarouf, M; Müller-Lung, U, 2009) |
| " He had been receiving methotrexate (MTX) since boyhood for severe psoriasis." | 3.75 | [Prolonged fever and monocytosis after hemorrhoidectomy and treatment with methotrexate--listeriosis with cerebral abscess]. ( Krämer, S; Maarouf, M; Müller-Lung, U, 2009) |
| "Acute generalized exanthemic pustulosis often presents dramatically with the abrupt onset of a widespread pustular eruption on an erythematous base, with a frequently positive Nikolsky sign." | 1.29 | Acute generalized exanthemic pustulosis. ( Heymann, WR; Manders, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krämer, S | 1 |
| Maarouf, M | 1 |
| Müller-Lung, U | 1 |
| Samieh-Tucker, A | 1 |
| Rupasinghe, M | 1 |
| Manders, SM | 1 |
| Heymann, WR | 1 |
| Brückner, V | 1 |
4 other studies available for metronidazole and Psoriasis
| Article | Year |
|---|---|
[Prolonged fever and monocytosis after hemorrhoidectomy and treatment with methotrexate--listeriosis with cerebral abscess].
Topics: Anti-Infective Agents; Biopsy, Needle; Brain; Brain Abscess; Diagnosis, Differential; Drug Therapy, | 2009 |
Anaesthesia for caesarean section in a patient with acute generalised pustular psoriasis.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2007 |
Acute generalized exanthemic pustulosis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ampicillin; Cefazolin; Dermatitis, Exfoliative; Diagn | 1994 |
Photosensitizers and radiosensitizers in dermatology and oncology.
Topics: Brain Neoplasms; DNA; Humans; Methoxsalen; Metronidazole; Misonidazole; Mycosis Fungoides; Photochem | 1979 |