khellin has been researched along with Psoriasis in 34 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study has been performed to search for the possible effect of khellin in psoriasis." | 9.05 | Preliminary report on the therapeutic effect of khellin in psoriasis. ( Abdel-Fattah, A; Aboul-Enein, MN; El-Menshawi, B; Wassel, G, 1983) |
| "Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient." | 5.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "A double-blind study has been performed to search for the possible effect of khellin in psoriasis." | 5.05 | Preliminary report on the therapeutic effect of khellin in psoriasis. ( Abdel-Fattah, A; Aboul-Enein, MN; El-Menshawi, B; Wassel, G, 1983) |
| "Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient." | 1.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "We analyzed the presence of mild cognitive impairment (CI) by using the PHES battery of psychometric tests and measured the levels of ammonia and of the inflammatory cytokines IL-6 and IL-18 in blood of patients with different types of liver or dermatological diseases resulting in different grades of hyperammonemia and/or inflammation." | 1.38 | Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. ( Cassinello, N; Civera, M; Felipo, V; Garcia-Torres, ML; Jordá, E; Martinez-Valls, J; Molina, I; Montesinos, E; Montoliu, C; Olmo, JA; Ortega, J; Serra, MA; Urios, A; Wassel, A, 2012) |
| "Keloid was identified in 13 boys and 10 girls, accounting for 0." | 1.34 | Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey. ( Chen, W; Cheng, YW; Lai, CS; Yang, YC, 2007) |
| "Indications for radiotherapy of benign dermatoses have decreased markedly during the past decades." | 1.26 | [Roentgen therapy of dermatoses: indications and hazards]. ( Goldschmidt, H, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (61.76) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Fattah, A | 1 |
| Aboul-Enein, MN | 1 |
| Wassel, G | 1 |
| El-Menshawi, B | 1 |
| Oddoze, L | 1 |
| Témime, P | 1 |
| Marchand, JP | 1 |
| Benne, M | 1 |
| Attwa, E | 1 |
| Khater, MH | 1 |
| Selim, HM | 1 |
| Essam, R | 1 |
| Ludwig, RJ | 1 |
| von Stebut, E | 1 |
| Balci, DD | 1 |
| Inandi, T | 1 |
| Dogramaci, CA | 1 |
| Celik, E | 1 |
| Felipo, V | 1 |
| Urios, A | 1 |
| Montesinos, E | 1 |
| Molina, I | 1 |
| Garcia-Torres, ML | 1 |
| Civera, M | 1 |
| Olmo, JA | 1 |
| Ortega, J | 1 |
| Martinez-Valls, J | 1 |
| Serra, MA | 1 |
| Cassinello, N | 1 |
| Wassel, A | 1 |
| Jordá, E | 1 |
| Montoliu, C | 1 |
| Zhang, X | 1 |
| Bloor, BK | 1 |
| Tidman, N | 1 |
| Leigh, IM | 1 |
| Odell, E | 1 |
| Dogan, B | 1 |
| Wollina, U | 1 |
| Ghali, L | 1 |
| Waseem, A | 1 |
| MONTGOMERY, RM | 1 |
| PORTNOY, M | 1 |
| RAAB, W | 1 |
| Stücker, M | 1 |
| Moll, C | 1 |
| Altmeyer, P | 1 |
| Handa, S | 1 |
| Dogra, S | 1 |
| Kaur, I | 1 |
| Yang, YC | 1 |
| Cheng, YW | 1 |
| Lai, CS | 1 |
| Chen, W | 1 |
| Panizzon, RG | 1 |
| Halder, RM | 1 |
| Thomas, JR | 1 |
| Doyle, JA | 1 |
| Konstantinova, NV | 1 |
| Lemak, NA | 1 |
| Duong, DM | 1 |
| Chuang, AZ | 1 |
| Urso, R | 1 |
| Duvic, M | 1 |
| Gasparro, FP | 1 |
| Goldschmidt, H | 2 |
| Lukacs, S | 1 |
| Braun-Falco, O | 1 |
| Wick, G | 2 |
| Kraft, D | 2 |
| Kokoschka, EM | 1 |
| Timpl, R | 2 |
| Kokschka, EM | 1 |
| Giannotti, B | 1 |
| Pimpinelli, N | 1 |
| Walther, H | 1 |
| Studnitsin, AA | 1 |
| Nikitina, MN | 1 |
| Lashmanova, AP | 1 |
| Nikitina, LV | 1 |
| Fleckman, PH | 1 |
| Jeffrey, JJ | 1 |
| Eisen, AZ | 1 |
| Sharapova, GIa | 1 |
| Khamaganova, AV | 1 |
| Marsden, CW | 1 |
| Engel, MF | 2 |
| Afanas'eva, OM | 1 |
| Schmid, AH | 1 |
| Groel, JT | 1 |
| Bowszyc, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Spa Therapy in the Treatment of Plaque Psoriasis, a Randomized, Controlled, Open Multicenter Study[NCT02098213] | 128 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| The Application of Preoperative Silicone Ointment and Its Effect on Wound Healing[NCT05461157] | 60 participants (Anticipated) | Interventional | 2022-11-14 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for khellin and Psoriasis
| Article | Year |
|---|---|
[Inflammatory dermatoses in skin of color].
Topics: Acne Vulgaris; Dermatitis, Atopic; Humans; Hyperpigmentation; Keloid; Psoriasis; Rosacea; Skin Pigme | 2023 |
Genome-wide association study of skin complex diseases.
Topics: Alopecia; Carcinoma, Basal Cell; Dermatitis, Atopic; Female; Genetic Predisposition to Disease; Geno | 2012 |
The therapeutic uses of topical vitamin A acid.
Topics: Acne Vulgaris; Animals; Callosities; Cocarcinogenesis; Fox-Fordyce Disease; Humans; Ichthyosis; Kelo | 1981 |
Topical corticosteroids. Which drug and when?
Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bites and Stings; Burns; | 1992 |
[Therapy of skin and venereal diseases. Review of the literature of 1967-68].
Topics: Acne Vulgaris; Alopecia; Balanitis; Candidiasis; Dermatitis, Occupational; Dermatomycoses; Diaper Ra | 1969 |
4 trials available for khellin and Psoriasis
| Article | Year |
|---|---|
Preliminary report on the therapeutic effect of khellin in psoriasis.
Topics: Adolescent; Adult; Double-Blind Method; Female; Heliotherapy; Humans; Khellin; Male; Middle Aged; Ps | 1983 |
Fluocinolone acetonide 0.2 per cent cream--a co-operative clinical trial.
Topics: Clinical Trials as Topic; Epidermolysis Bullosa; Fluocinolone Acetonide; Folliculitis; Granuloma; Hu | 1968 |
Dimethyl sulfoxide (DMSO) in clinical dermatology.
Topics: Amyloidosis; Cicatrix; Clinical Trials as Topic; Dimethyl Sulfoxide; Eczema; Female; Humans; Keloid; | 1966 |
Dimethyl sulfoxide as a vehicle for corticosteroids. A comparison with the occlusive dressing technique.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Atopic; Dermatitis, Contact; Eczema; F | 1968 |
25 other studies available for khellin and Psoriasis
| Article | Year |
|---|---|
[Combined oral meladinine and ultraviolet rays in the treatment of psoriasis. (Preliminary note)].
Topics: Humans; Khellin; Male; Methoxsalen; Middle Aged; Psoriasis; Ultraviolet Therapy | 1967 |
Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis.
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Hyperpigmentation; Injections, Intralesional; Keloi | 2022 |
DLQI scores in patients with keloids and hypertrophic scars: a prospective case control study.
Topics: Adult; Case-Control Studies; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Prospective Studi | 2009 |
Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy.
Topics: Adult; Aged; Ammonia; Cognitive Dysfunction; Fatty Liver; Female; Hepatic Encephalopathy; Humans; Hy | 2012 |
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; Breast; Cell Division; DNA Primers; Epidermal Cells; | 2003 |
TRIAMCINOLONE ACETONIDE INJECTED SUBLESIONALLY IN THE TREATMENT OF DERMATOSES.
Topics: Asian People; Black People; Dermatitis; Dermatology; Eczema; Geriatrics; Granuloma; Humans; Keloid; | 1963 |
[EXPERIENCES WITH INTRALESIONAL CORTICOSTEROID TREATMENT OF SEVERAL SKIN DISEASES].
Topics: Adrenal Cortex Hormones; Alopecia Areata; Cheilitis; Eczema; Granuloma; Humans; Injections; Keloid; | 1964 |
[Cutaneous oxygen supply. With special consideration of skin uptake of oxygen from the atmosphere].
Topics: Blood Gas Monitoring, Transcutaneous; Capillary Permeability; Cell Division; Diffusion; Humans; Kelo | 2004 |
Pustular psoriasis over keloids: is it a Koebner phenomenon?
Topics: Adult; Female; Hand; Humans; Keloid; Psoriasis; Thorax | 2006 |
Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey.
Topics: Acne Vulgaris; Alopecia Areata; Chi-Square Distribution; Child; Cross-Sectional Studies; Dermatitis, | 2007 |
[Dermatologic radiotherapy].
Topics: Eczema; Humans; Keloid; Lymphoma, B-Cell; Lymphoma, T-Cell, Cutaneous; Palliative Care; Precancerous | 2007 |
Hair and scalp disorders in blacks.
Topics: Alopecia; Black People; Cellulitis; Dermatitis, Seborrheic; Folliculitis; Hair Diseases; Hair Prepar | 1983 |
Artificial skin equivalent differentiation depends on fibroblast donor site: use of eyelid fibroblasts.
Topics: Adolescent; Adult; Aged; Cell Differentiation; Cells, Cultured; Epidermal Cells; Eyelids; Female; Fi | 1998 |
p53 in dermatology.
Topics: Animals; Carcinoma, Squamous Cell; DNA Damage; DNA Repair; Extracellular Matrix; Fibroblasts; Furoco | 1998 |
[Roentgen therapy of dermatoses: indications and hazards].
Topics: Acne Vulgaris; Eczema; Foot Dermatoses; Humans; Keloid; Lichen Planus; Lymphocytosis; Neoplasms, Rad | 1978 |
Radiotherapy of benign dermatoses: indications, practice, and results.
Topics: Acne Vulgaris; Bacterial Infections; Dupuytren Contracture; Eczema; Female; Hemangioma; Herpes Simpl | 1978 |
The diagnostic application of specific anti-procollagen sera. I. Analysis of skin biopsies.
Topics: Adolescent; Adult; Aged; Humans; Immune Sera; Keloid; Lichen Planus; Lupus Erythematosus, Discoid; L | 1976 |
Defined immunofluorescence studies of anticollagen sera.
Topics: Collagen; Epidermolysis Bullosa; Fluorescent Antibody Technique; Glucocorticoids; Immune Sera; Keloi | 1975 |
[Treatment of dermatoses in children with synalar-forte, synalar-gel and metosyn].
Topics: Acetates; Adolescent; Child; Child, Preschool; Drug Evaluation; Eczema; Fluocinolone Acetonide; Gran | 1974 |
A sensitive microassay for prolyl hydroxylase: activity in normal and psoriatic skin.
Topics: Animals; Ascorbic Acid; Catalase; Chick Embryo; Collagen; Dithiothreitol; Humans; Iron; Keloid; Keto | 1973 |
[Treatment of some dermatoses by the intradermal injections of a 10 percent solution of quingamine].
Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Injections, Intradermal; Keloid; Lupus Erythema | 1973 |
Indications and contraindications for the use of DMSO in clinical dermatology.
Topics: Amyloidosis; Animals; Anura; Dimethyl Sulfoxide; Dogs; Eczema; Humans; Keloid; Keratosis; Lichen Pla | 1967 |
[Our experience in the treatment of certain dermatoses with ultra-soft roentgen rays (Bucky rays)].
Topics: Adolescent; Adult; Cheilitis; Eczema; Female; Humans; Keloid; Lichen Planus; Male; Middle Aged; Neur | 1969 |
[Local treatment of skin diseases with Volon A tincture].
Topics: Alopecia Areata; Benzalkonium Compounds; Dermatologic Agents; Eczema; Humans; Keloid; Lichen Planus; | 1967 |
[Treatment of various skin diseases with topical injections of hydrocortisone].
Topics: Administration, Topical; Anti-Inflammatory Agents; Humans; Hydrocortisone; Injections, Intradermal; | 1968 |