Page last updated: 2024-10-23

benzo(a)pyrene and Psoriasis

benzo(a)pyrene has been researched along with Psoriasis in 8 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Coal tar treated psoriasis patients were used as a model population to evaluate a panel of immunoassays for monitoring exposure to benzo[a]pyrene (BP) and related polycyclic aromatic hydrocarbons (PAH)."1.29Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype. ( Beachman, A; Chiamprasert, S; DeLeo, VA; Lin, JH; Perera, FP; Santella, RM; Tang, D; Wang, LW; Young, TL; Zhang, YJ, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borska, L2
Andrys, C2
Krejsek, J1
Palicka, V2
Chmelarova, M2
Hamakova, K2
Kremlacek, J2
Fiala, Z2
Beranek, M1
Mason, G1
Rawlins, MD1
Shuster, S1
Bickers, DR1
Mukhtar, H1
Dutta-Choudhury, T1
Marcelo, CL1
Voorhees, JJ1
Santella, RM1
Perera, FP1
Young, TL1
Zhang, YJ1
Chiamprasert, S1
Tang, D1
Wang, LW1
Beachman, A1
Lin, JH1
DeLeo, VA1
Phillips, DH1
Alldrick, AJ1
Paleologo, M1
van Schooten, FJ1
Pavanello, S2
Kriek, E1
Zordan, M1
Clonfero, E1
Bezze, C1
Levis, AG2

Other Studies

8 other studies available for benzo(a)pyrene and Psoriasis

ArticleYear
Oxidative damage to nucleic acids and benzo(a)pyrene-7,8-diol-9,10-epoxide-DNA adducts and chromosomal aberration in children with psoriasis repeatedly exposed to crude coal tar ointment and UV radiation.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adolescent; Benzo(a)pyrene; Child; Child, Presch

2014
Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy.
    Toxicology letters, 2016, Jul-25, Volume: 255

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Administration, Cutaneous; Adult; Aged; Aged, 80

2016
Blood monocyte aryl hydrocarbon hydroxylase activity in psoriasis.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:3

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Female; Human

1983
Aryl hydrocarbon hydroxylase, epoxide hydrolase, and benzo[a]-pyrene metabolism in human epidermis: comparative studies in normal subjects and patients with psoriasis.
    The Journal of investigative dermatology, 1984, Volume: 83, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; C

1984
Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype.
    Mutation research, 1995, Volume: 334, Issue:2

    Topics: Benzo(a)pyrene; Biomarkers; Carcinogens; Case-Control Studies; Coal Tar; DNA Adducts; Environmental

1995
Tumorigenicity of a combination of psoriasis therapies.
    British journal of cancer, 1994, Volume: 69, Issue:6

    Topics: Adenosine Triphosphate; Administration, Topical; Animals; Anthralin; Benzo(a)pyrene; Carcinogens; Co

1994
Detection of benzo[a]pyrene-diol-epoxide-DNA adducts in white blood cells of psoriatic patients treated with coal tar.
    Mutation research, 1992, Volume: 281, Issue:1

    Topics: Adult; Analysis of Variance; Benzo(a)pyrene; Coal Tar; DNA; DNA Adducts; DNA Damage; Dose-Response R

1992
Coal tar therapy does not influence in vitro benzo[a]pyrene metabolism and DNA adduct formation in peripheral blood lymphocytes of psoriatic patients.
    Carcinogenesis, 1992, Volume: 13, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Benzo(a)pyrene; Cells, Cultured; Co

1992