pyrimethamine has been researched along with Psoriasis in 4 studies
Maloprim: contains above 2 cpds
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrimethamine, a folate antagonist similar to methrotrexate without known hepatotoxcity in man, was administer orally, once a week, to seven patients with severe, long-standing psoriasis." | 7.65 | Treatment of servere psoriasis with pyrimethamine. ( Aeling, JL; Andreozzi, RJ; DiBella, NJ; Nuss, DD, 1977) |
| "Pyrimethamine, a folate antagonist similar to methrotrexate without known hepatotoxcity in man, was administer orally, once a week, to seven patients with severe, long-standing psoriasis." | 3.65 | Treatment of servere psoriasis with pyrimethamine. ( Aeling, JL; Andreozzi, RJ; DiBella, NJ; Nuss, DD, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinstein, GD | 2 |
| McCullough, JL | 2 |
| Eaglstein, WH | 1 |
| Golub, A | 1 |
| Cornell, RC | 1 |
| Stoughton, RB | 1 |
| Clendenning, W | 1 |
| Zackheim, H | 1 |
| Maibach, H | 1 |
| Kulp, KR | 1 |
| King, L | 1 |
| Baden, HP | 1 |
| Taylor, JS | 1 |
| Deneau, DD | 1 |
| DiBella, NJ | 1 |
| Nuss, DD | 1 |
| Aeling, JL | 1 |
| Andreozzi, RJ | 1 |
| Hynes, JB | 1 |
| Gaspar, AP | 1 |
| Gaspar, NK | 1 |
1 trial available for pyrimethamine and Psoriasis
| Article | Year |
|---|---|
A clinical screening program for topical chemotherapeutic drugs in psoriasis.
Topics: Adult; Animals; Clinical Trials as Topic; Cycloheximide; Dermatologic Agents; Double-Blind Method; D | 1981 |
3 other studies available for pyrimethamine and Psoriasis
| Article | Year |
|---|---|
Treatment of servere psoriasis with pyrimethamine.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Gastrointestinal Diseases; Hematologic Diseas | 1977 |
In vitro screening of biochemical activity of folic acid antagonists in skin.
Topics: Animals; Animals, Newborn; Chlorobenzenes; Depression, Chemical; DNA; Folic Acid Antagonists; Methot | 1977 |
[A case of psoriasis with palmo-plantar manifestations treated with pyrimethamine].
Topics: Adult; Foot Dermatoses; Hand Dermatoses; Humans; Male; Psoriasis; Pyrimethamine | 1968 |