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dimercaprol and Psoriasis

dimercaprol has been researched along with Psoriasis in 6 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis."9.05Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984)
"Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis."5.05Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ENNEKING, JH1
PETERS, HJ1
SEROPIAN, KA1
VONKENNEL, J1
SCHOBERL, A1
Dequeker, J1
Verdickt, W1
Gevers, G1
Vanschoubroek, K1
Tsyganok, SS1
Burdeĭnyĭ, AP1
Sigidin, IaA1
Novoselova, TM1

Trials

3 trials available for dimercaprol and Psoriasis

ArticleYear
Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis.
    Clinical rheumatology, 1984, Volume: 3 Suppl 1

    Topics: Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clini

1984
[Unithiol in the treatment of dermatoses].
    Vestnik dermatologii i venerologii, 1978, Issue:9

    Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Dimercaprol; Drug Evaluation; Eczema;

1978
[Treatment of psoriatic arthritis with gold salts (chrysotherapy)].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:7

    Topics: Adult; Arthritis; Clinical Trials as Topic; Dimercaprol; Drug Therapy, Combination; Female; Gold; Hu

1986

Other Studies

3 other studies available for dimercaprol and Psoriasis

ArticleYear
[NEPHROTIC SYNDROME AFTER PROLONGED USE OF A MERCURIAL OINTMENT. MERCURY EXCRETION DURING TREATMENT WITH BAL AND N-ACETYL-DL-PENICILLAMINE].
    Nederlands tijdschrift voor geneeskunde, 1964, Feb-08, Volume: 108

    Topics: Adolescent; Body Fluids; Dimercaprol; Mercury; Mercury Poisoning; Nephrotic Syndrome; Ointments; Pen

1964
[THE BLOOD GLUTATHIONE CONTENT OF PSORIASIS PATIENTS].
    Vestnik dermatologii i venerologii, 1963, Volume: 37

    Topics: Blood Chemical Analysis; Dimercaprol; Glutathione; Humans; Psoriasis

1963
BAL and the treatment of syphilis and psoriasis with thiolopriven substances.
    Medizinische Monatsschrift, 1949, Volume: 3, Issue:8

    Topics: Dimercaprol; Psoriasis; Syphilis

1949