dimercaprol has been researched along with Psoriasis in 6 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
Excerpt | Relevance | Reference |
---|---|---|
"Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis." | 9.05 | Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984) |
"Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis." | 5.05 | Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
ENNEKING, JH | 1 |
PETERS, HJ | 1 |
SEROPIAN, KA | 1 |
VONKENNEL, J | 1 |
SCHOBERL, A | 1 |
Dequeker, J | 1 |
Verdickt, W | 1 |
Gevers, G | 1 |
Vanschoubroek, K | 1 |
Tsyganok, SS | 1 |
Burdeĭnyĭ, AP | 1 |
Sigidin, IaA | 1 |
Novoselova, TM | 1 |
3 trials available for dimercaprol and Psoriasis
Article | Year |
---|---|
Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clini | 1984 |
[Unithiol in the treatment of dermatoses].
Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Dimercaprol; Drug Evaluation; Eczema; | 1978 |
[Treatment of psoriatic arthritis with gold salts (chrysotherapy)].
Topics: Adult; Arthritis; Clinical Trials as Topic; Dimercaprol; Drug Therapy, Combination; Female; Gold; Hu | 1986 |
3 other studies available for dimercaprol and Psoriasis
Article | Year |
---|---|
[NEPHROTIC SYNDROME AFTER PROLONGED USE OF A MERCURIAL OINTMENT. MERCURY EXCRETION DURING TREATMENT WITH BAL AND N-ACETYL-DL-PENICILLAMINE].
Topics: Adolescent; Body Fluids; Dimercaprol; Mercury; Mercury Poisoning; Nephrotic Syndrome; Ointments; Pen | 1964 |
[THE BLOOD GLUTATHIONE CONTENT OF PSORIASIS PATIENTS].
Topics: Blood Chemical Analysis; Dimercaprol; Glutathione; Humans; Psoriasis | 1963 |
BAL and the treatment of syphilis and psoriasis with thiolopriven substances.
Topics: Dimercaprol; Psoriasis; Syphilis | 1949 |