papaverine has been researched along with Psoriasis in 7 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klemp, P | 1 |
| Reimer, G | 1 |
| Mentzer, M | 1 |
| Gottschalk, K | 1 |
| Neufahrt, A | 1 |
| Kalamkarian, AA | 1 |
| Frolov, EP | 1 |
| Mordovtsev, VN | 1 |
| Stawiski, MA | 1 |
| Powell, JA | 1 |
| Lang, PG | 1 |
| Schork, A | 1 |
| Duell, EA | 3 |
| Voorhees, JJ | 3 |
| Iizuka, H | 1 |
| Adachi, K | 1 |
| Halprin, KM | 1 |
| Levine, V | 1 |
| Rusin, LJ | 1 |
1 review available for papaverine and Psoriasis
| Article | Year |
|---|---|
[Present-day status of the problem of psoriasis and the tasks of its development].
Topics: Cell Division; HLA Antigens; Humans; Methoxsalen; Neurotransmitter Agents; Papaverine; Psoriasis; Ul | 1979 |
1 trial available for papaverine and Psoriasis
| Article | Year |
|---|---|
Papaverine: its effects on cyclic AMP in vitro and psoriasis in vivo.
Topics: Animals; Cyclic AMP; Depression, Chemical; Humans; Mice; Papaverine; Psoriasis; Skin | 1975 |
5 other studies available for papaverine and Psoriasis
| Article | Year |
|---|---|
Local regulation of cutaneous blood flow in psoriasis.
Topics: Adult; Aged; Capillaries; Female; Homeostasis; Humans; Lidocaine; Male; Middle Aged; Papaverine; Pos | 1984 |
Influence of intercellular agents on proliferation and gene activity of cultured human skin epithelium cells (NCTC 2544).
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Chromosomal Proteins, Non-Histone; DNA Replication | 1981 |
Imbalanced cyclic AMP-cyclic GMP levels in psoriasis.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; | 1975 |
Cyclic AMP accumulation in psoriatic skin: differential responses to histamine, AMP, and einephrine by the uninvolved and involved epidermis.
Topics: Adenosine Monophosphate; Cyclic AMP; Drug Interactions; Epidermis; Epinephrine; Histamine; Humans; I | 1978 |
Papaverine and Ro 20-1724 inhibit cyclic nucleotide phosphodiesterase activity and increase cyclic AMP levels in psoriatic epidermis in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzy | 1978 |