Page last updated: 2024-10-15

5-(4-aminophenyl)-10,15,20-triphenylporphyrin

Description

5-(4-aminophenyl)-10,15,20-triphenylporphyrin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135423398
CHEMBL ID3408510
SCHEMBL ID3999312
MeSH IDM0545823

Synonyms (15)

Synonym
5-(4-aminophenyl)-10,15,20-triphenyl porphine
67605-64-5
SCHEMBL3999312
4-(10,15,20-triphenyl-21h,23h-porphin-5-yl)benzenamine
CHEMBL3408510
5-(4-aminophenyl)-10,15,20-triphenylporphyrin
4-(10,15,20-triphenylporphyrin-5-yl)phenylamine
5-(4-aminophenyl)-10,15,20-(triphenyl)porphyrin
5-(4-aminophenyl)-10,15,20-tris(phenyl)porphyrin
BS-47662
YSWG152
4-(10,15,20-triphenyl-21,23-dihydroporphyrin-5-yl)aniline
5-(4-aminophenyl)-10,15,20-triphenylporphine
CS-0086506
E85151
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (22)

Assay IDTitleYearJournalArticle
AID1336589Photostability of compound in aqueous media assessed as amount of soret band remaining after irradiation with white light at 100 mW/cm'2 for 30 mins by UV-spectrophotometric analysis2017Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2
Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
AID1196021Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 0.49 uM to 7.8 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196018Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 3.91 uM to 62.50 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196015Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196014Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196009Bactericidal activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196016Antibacterial activity against methicillin-resistant Staphylococcus aureus at 3.91 uM to 62.50 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196013Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1336590Phototoxicity against human HaCaT cells assessed as cell viability at 1 uM after irradiation with light at 180 J/cm'2 for 30 mins by MTT assay2017Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2
Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
AID1195998Photostability at 2 x 10'-5 mol/L exposed to 4.2 mW/cm2 light energy density assessed as change in absorption spectra after 30 mins post irradiation2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196008Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1336591Induction of singlet oxygen production assessed as amount of DPiBF remaining after irradiation with light at 9 mW/cm'2 for 30 mins by DPiBF photooxidation based spectrophotometric analysis (Rvb = 80%)2017Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2
Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes.
AID1196012Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196007Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196020Antibacterial activity against Escherichia coli ATCC 25922 at 0.49 uM to 7.8 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196004Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196019Antibacterial activity against methicillin-resistant Staphylococcus aureus at 0.49 uM to 7.8 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196010Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196006Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196005Bactericidal activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196011Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196017Antibacterial activity against Escherichia coli ATCC 25922 at 3.91 uM to 62.50 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]