azauridine has been researched along with Psoriasis in 31 studies
Azauridine: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An open study was made of 25 patients with severe, recalcitrant psoriasis treated with azaribine (6-azauridine triacetate)." | 3.65 | The treatment of psoriasis with azaribine. ( Deneau, DG; Farber, EM, 1975) |
| "The chemotherapy of psoriasis is reviewed in 246 patients from 1964 to 1974 treated with methotrexate, 92 patients from 1971 to 1974 with hydroxyurea, and 36 patients from 1972 to 1974 with azaribine." | 1.26 | Chemotherapy of psoriasis: ten years of experience. ( Moschella, SL, 1976) |
| "Azaribine is an effective agent in the treatment of psoriasis." | 1.26 | Anemia of azaribine in the treatment of psoriasis. ( Cornell, RC; Fox, RM; Milstein, HG; Stoughton, RB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TURNER, RW | 1 |
| CALABRESI, P | 4 |
| McDonald, CJ | 7 |
| Burton, JL | 1 |
| Matthews, CN | 1 |
| Raab, W | 1 |
| Gmeiner, B | 1 |
| Muckenhuber, P | 1 |
| Doolittle, CH | 2 |
| Shubin, S | 1 |
| Groth, O | 1 |
| Klem, EB | 1 |
| Farber, EM | 2 |
| Pearlman, D | 1 |
| Abel, EA | 1 |
| Rees, RB | 1 |
| Van Scott, EJ | 1 |
| Moschella, SL | 2 |
| Bergstresser, PR | 1 |
| Schreiber, SH | 1 |
| Weinstein, GD | 1 |
| Ruszczak, Z | 1 |
| Cornell, RC | 2 |
| Milstein, HG | 2 |
| Fox, RM | 1 |
| Stoughton, RB | 2 |
| Heppner, GH | 1 |
| Crutcher, WA | 1 |
| Baker, H | 1 |
| Keefer, RA | 1 |
| Roenigk, HH | 1 |
| Hawk, WA | 1 |
| Deneau, DG | 1 |
| Alper, JC | 1 |
| Wiemann, MC | 1 |
| Rueckl, FS | 1 |
| Elis, J | 3 |
| Rasková, H | 2 |
| Dantzig, PI | 1 |
| McEvoy, B | 1 |
| Mauro, J | 1 |
| Rayhanzadeh, S | 1 |
| Perlík, F | 1 |
| Kubíková, M | 1 |
| Jankú, I | 1 |
5 reviews available for azauridine and Psoriasis
| Article | Year |
|---|---|
The uses of systemic chemotherapeutic agents in psoriasis.
Topics: Administration, Topical; Anthralin; Azathioprine; Azauridine; Chemical Phenomena; Chemistry; Humans; | 1981 |
An appraisal of current systemic chemotherapy for psoriasis.
Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azauridine; Cell Division | 1976 |
Psoriasis: a review. II.
Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lom | 1975 |
Chemotherapy of psoriasis.
Topics: Azauridine; Central Nervous System; Digestive System; Hematopoietic System; Humans; Hydroxyurea; Liv | 1975 |
New indications for 6-azauridine treatment in man. A review.
Topics: Adult; Animals; Antiviral Agents; Azauridine; Child, Preschool; Clinical Trials as Topic; Female; He | 1972 |
6 trials available for azauridine and Psoriasis
| Article | Year |
|---|---|
Double-blind controlled crossover high-dose study of Azaribine in psoriasis.
Topics: Adult; Azauridine; Brain Diseases; Clinical Trials as Topic; Electroencephalography; Female; Humans; | 1975 |
Azaribine (Triazure) for severe psoriasis.
Topics: Antimetabolites; Azauridine; Child; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Metho | 1976 |
Rationally designed combination chemotherapy for the treatment of patients with recalcitrant psoriasis.
Topics: Adult; Aged; Azauridine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; | 1985 |
New indications for 6-azauridine treatment in man. A review.
Topics: Adult; Animals; Antiviral Agents; Azauridine; Child, Preschool; Clinical Trials as Topic; Female; He | 1972 |
Azaribine in the treatment of psoriasis. A low dose, double-blind evaluation.
Topics: Adult; Aged; Azauridine; Biopsy; Carboxy-Lyases; Clinical Trials as Topic; Female; Hematocrit; Human | 1973 |
Low dose azaribine in the treatment of psoriasis.
Topics: Adult; Aged; Anemia; Aphasia; Arthritis; Azauridine; Clinical Trials as Topic; Coma; Headache; Human | 1974 |
21 other studies available for azauridine and Psoriasis
| Article | Year |
|---|---|
THE EFFECT OF TRIACETYL AZAURIDINE ON PSORIASIS.
Topics: Anemia; Azauridine; Drug Therapy; Hematopoietic System; Humans; Mycosis Fungoides; Nucleosides; Path | 1964 |
Letter: Thrombosis and psoriasis.
Topics: Azauridine; Psoriasis; Thrombosis | 1976 |
Azaribine (triacetyl-6-azauridine) in psoriasis. Screening by in vitro methods.
Topics: Azauridine; Chemical Phenomena; Chemistry; Cyclic AMP; Humans; Oxygen Consumption; Psoriasis | 1977 |
When to try antineoplastic agents in psoriasis.
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Kidney Function Tests; Liver Function Tests; | 1977 |
Pharmacological studies of neurotoxicity in patients with psoriasis treated with azaribine, utilizing high-pressure liquid chromatography.
Topics: Adult; Aged; Azauridine; Central Nervous System Diseases; Chromatography, High Pressure Liquid; Dose | 1977 |
Triazure and public drug policies.
Topics: Azauridine; Legislation, Drug; Psoriasis; Risk; United States; United States Food and Drug Administr | 1979 |
[Cytostatic therapy of psoriasis].
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1979 |
Effects of antipsoriasis drugs and metabolic inhibitors on the growth of epidermal cells in culture.
Topics: Animals; Anthralin; Antimetabolites; Azauridine; Cell Division; Cells, Cultured; Cycloheximide; Cyta | 1978 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine | 1976 |
Therapy of psoriasis 1975.
Topics: Administration, Topical; Adrenal Cortex Hormones; Azauridine; Depression, Chemical; Ficusin; Humans; | 1976 |
Guidelines for use of azaribine in treatment of psoriasis.
Topics: Azauridine; Drug Administration Schedule; Humans; Psoriasis | 1976 |
Chemotherapy of psoriasis: ten years of experience.
Topics: Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis; Retrospective Studies | 1976 |
Systemic chemotherapy for psoriasis: a national survey.
Topics: Adult; Azauridine; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Utiliz | 1976 |
[Immunosuppressive agents in the treatment of psoriasis].
Topics: Azauridine; Cyclophosphamide; Drug Evaluation; Humans; Hydroxyurea; Immunosuppressive Agents; Methot | 1976 |
Anemia of azaribine in the treatment of psoriasis.
Topics: Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Azauridine; Erythrocytes; Female; Humans; Ma | 1976 |
Nucleoside analogs in the treatment of nonneoplastic diseases.
Topics: Animals; Arthritis; Azauridine; Cytarabine; Female; Humans; Idoxuridine; Immunosuppression Therapy; | 1975 |
Azaribine therapy for psoriasis. Evaluation of potential effects on the liver and other organ systems.
Topics: Adolescent; Adult; Azauridine; Biopsy; Brain; Cardiovascular System; Chemical and Drug Induced Liver | 1975 |
The treatment of psoriasis with azaribine.
Topics: Adolescent; Adult; Aged; Azauridine; Drug Evaluation; Female; Humans; Male; Middle Aged; Psoriasis | 1975 |
Cutaneous uses of the antiproliferative drugs.
Topics: Administration, Topical; Antimetabolites; Azauridine; Bleomycin; Chemical and Drug Induced Liver Inj | 1974 |
Antibody response in psoriatic patients treated with 6-azauridine-triacetate.
Topics: Antibody Formation; Azauridine; Humans; Immunization; Immunization, Secondary; Middle Aged; Psoriasi | 1973 |
Time-response curves in the evaluation of the clinical efficacy of drugs.
Topics: Acetates; Administration, Oral; Antimetabolites; Azauridine; Evaluation Studies as Topic; Humans; Mo | 1971 |