Page last updated: 2024-10-16

aminolevulinic acid and Psoriasis

aminolevulinic acid has been researched along with Psoriasis in 37 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"To study the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in ALA-PDT in patients with psoriasis."9.12A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis. ( Gerritsen, MJ; Kleinpenning, MM; Smits, T; van de Kerkhof, PC; van Erp, PE, 2006)
"We first set up imiquimod-induced dermatitis in mice that closely resembles human psoriasis lesions."7.81Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"We established the topical delivery profiles of anti-psoriatic drugs via imiquimod-treated psoriasis-like skin."7.81Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"Psoriasis lesions accumulate protoporphyrin IX (PpIX) with a variable distribution within plaques due to variations in hyperkeratosis causing differences in penetration of cream or light."7.76The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis. ( Gerritsen, RM; Kanis, JH; Kleinpenning, MM; Smits, T; van de Kerkhof, P; van Erp, PE, 2010)
" This paper describes the accumulation of the photosensitizing agent protoporphyrin IX in areas of plaque psoriasis by monitoring of the fluorescence emission induced by low-intensity laser excitation at 488 nm."7.69The accumulation of protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy. ( Collins, P; Robinson, DJ; Sheehan-Dare, RA; Stables, GI; Stringer, MR, 1996)
"Tacrolimus flux was enhanced from 2 to 21 μg/cm2/h by imiquimod intervention."5.42Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"Psoriasis is a chronic inflammatory skin disease and topical therapy remains a key role for treatment."5.42Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"To study the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in ALA-PDT in patients with psoriasis."5.12A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis. ( Gerritsen, MJ; Kleinpenning, MM; Smits, T; van de Kerkhof, PC; van Erp, PE, 2006)
"Photodynamic therapy for psoriasis showed promise in the early 1990s with reports of plaque clearance following topical aminolevulinic acid - photodynamic therapy (ALA-PDT)."4.91Photodynamic therapy for psoriasis. ( Adelzadeh, L; Choi, YM; Wu, JJ, 2015)
"We have reviewed the results of clinical investigations into the use of photodynamic therapy (PDT) with intravenous injection of hematoporphyrin derivative (HpD), Photofrin (PF) and Sn-protoporphyrin (Sn-Pp) or oral administration of delta-aminolevulinic acid in the treatment of skin cancers and/or psoriasis."4.79Photodynamic therapy with systemic administration of photosensitizers in dermatology. ( Calzavara-Pinton, PG; Ortel, B; Szeimies, RM; Zane, C, 1996)
"In this study, we first revealed that ALA-PDT treatment effectively ameliorated the psoriasis-like lesion in imiquimod (IMQ)-induced mouse model and further explored the potential molecular mechanism and related signalling pathways during the treatment."3.91ALA-PDT alleviates the psoriasis by inhibiting JAK signalling pathway. ( Chen, X; Fang, F; Yi, F; Zhang, J; Zheng, X; Zhou, B, 2019)
"We first set up imiquimod-induced dermatitis in mice that closely resembles human psoriasis lesions."3.81Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"We established the topical delivery profiles of anti-psoriatic drugs via imiquimod-treated psoriasis-like skin."3.81Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"To observe the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) for treating psoriasis vulgaris in guinea pigs."3.77[Therapeutic effect of photodynamic treatment for psoriasis vulgaris in guinea pigs]. ( Duan, SJ; Li, KY; Liu, HW; Xie, GH, 2011)
"Psoriasis lesions accumulate protoporphyrin IX (PpIX) with a variable distribution within plaques due to variations in hyperkeratosis causing differences in penetration of cream or light."3.76The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis. ( Gerritsen, RM; Kanis, JH; Kleinpenning, MM; Smits, T; van de Kerkhof, P; van Erp, PE, 2010)
"Psoriasis has been shown to highly accumulate protoporphyrin IX (PpIX), but a variable distribution within plaques after fluorescence diagnosis is seen."3.73Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study. ( Ewalds, E; Gerritsen, MJ; Kleinpenning, MM; Smits, T; van de Kerkhof, PC; van Erp, PE, 2006)
"Photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) has been shown in previous studies to improve psoriasis."3.71Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells. ( Bissonnette, R; Korbelik, M; Lui, H; McLean, DI; Zeng, H, 2001)
" This paper describes the accumulation of the photosensitizing agent protoporphyrin IX in areas of plaque psoriasis by monitoring of the fluorescence emission induced by low-intensity laser excitation at 488 nm."3.69The accumulation of protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy. ( Collins, P; Robinson, DJ; Sheehan-Dare, RA; Stables, GI; Stringer, MR, 1996)
"We report a case of psoriasis reactivation following photodynamic therapy with delta-aminolevulinic acid."3.69Købner reaction induced by photodynamic therapy using delta-aminolevulinic acid. A case report. ( Stender, IM; Wulf, HC, 1996)
"Its use in the treatment of psoriasis has been attempted only quite recently and some modest success achieved."2.39Photodynamic therapy for psoriasis? ( Fergin, P, 1996)
"Bowen's disease was highly responsive, provided that adequate light and HpD or PF doses were delivered."2.39Photodynamic therapy with systemic administration of photosensitizers in dermatology. ( Calzavara-Pinton, PG; Ortel, B; Szeimies, RM; Zane, C, 1996)
"In spite of significant advances in the treatment of psoriasis, more effective and safer therapeutic strategies are still needed."1.46Systemic ALA-PDT effectively blocks the development of psoriasis-like lesions and alleviates leucocyte infiltration in the K14-VEGF transgenic mouse. ( Chen, T; Fu, LX; Guo, ZP; Liu, XY; Wu, YB; Zhang, LW, 2017)
"Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders."1.46Systemic ALA-PDT effectively blocks the development of psoriasis-like lesions and alleviates leucocyte infiltration in the K14-VEGF transgenic mouse. ( Chen, T; Fu, LX; Guo, ZP; Liu, XY; Wu, YB; Zhang, LW, 2017)
"Psoriasis is a chronic inflammatory skin disorder that greatly affects the patient's quality of life."1.46Photodynamic therapy with 5-aminolevulinic acid suppresses IFN-γ-induced K17 expression in HaCaT cells via MAPK pathway. ( Sun, Q; Wang, XL, 2017)
"Tacrolimus flux was enhanced from 2 to 21 μg/cm2/h by imiquimod intervention."1.42Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"Psoriasis is a chronic inflammatory skin disease and topical therapy remains a key role for treatment."1.42Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. ( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"PDL seems to be effective in the treatment of nail psoriasis and improves nail matrix and nail bed involvement."1.35Pulsed dye laser vs. photodynamic therapy in the treatment of refractory nail psoriasis: a comparative pilot study. ( Fernández-Guarino, M; García-Morales, I; Harto, A; Jaén, P; Sánchez-Ronco, M, 2009)
"Nail psoriasis is often refractory to traditional treatments, and patients with nail psoriasis usually demand a therapeutic option."1.35Pulsed dye laser vs. photodynamic therapy in the treatment of refractory nail psoriasis: a comparative pilot study. ( Fernández-Guarino, M; García-Morales, I; Harto, A; Jaén, P; Sánchez-Ronco, M, 2009)
"Psoriasis has been shown to highly accumulate protoporphyrin IX (PpIX), but a variable distribution within plaques after fluorescence diagnosis is seen."1.33Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study. ( Ewalds, E; Gerritsen, MJ; Kleinpenning, MM; Smits, T; van de Kerkhof, PC; van Erp, PE, 2006)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (24.32)18.2507
2000's17 (45.95)29.6817
2010's10 (27.03)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Chen, T1
Zhang, LW1
Fu, LX1
Wu, YB1
Liu, XY1
Guo, ZP1
Wen, X1
Li, Y1
Hamblin, MR1
Wang, XL1
Sun, Q1
Yi, F1
Zheng, X1
Fang, F1
Zhang, J1
Zhou, B1
Chen, X1
Choi, YM1
Adelzadeh, L1
Wu, JJ1
Lin, YK1
Yang, SH1
Chen, CC1
Kao, HC1
Fang, JY1
Shokeen, D1
Smits, T5
van Laarhoven, AI1
Staassen, A1
van de Kerkhof, PC4
van Erp, PE5
Gerritsen, MJ4
Fernández-Guarino, M1
Harto, A1
Sánchez-Ronco, M1
García-Morales, I1
Jaén, P1
Fang, YP1
Huang, YB1
Wu, PC1
Tsai, YH1
Kleinpenning, MM3
Kanis, JH1
van de Kerkhof, P1
Gerritsen, RM1
Xie, GH1
Li, KY1
Liu, HW1
Duan, SJ1
Lee, Y1
Baron, ED1
Bissonnette, R2
Tremblay, JF1
Juzenas, P1
Boushira, M1
Lui, H2
Beattie, PE1
Dawe, RS1
Ferguson, J1
Ibbotson, SH2
Radakovic-Fijan, S2
Blecha-Thalhammer, U1
Schleyer, V2
Szeimies, RM4
Zwingers, T2
Hönigsmann, H1
Tanew, A2
Fergin, P2
Robles, CA1
Yim, YC1
Lee, ES2
Chung, PS1
Rhee, CK1
Fransson, J1
Ros, AM1
Karrer, S2
Landthaler, M2
Ewalds, E1
Kim, JY1
Kang, HY1
Kim, YC1
Boehncke, WH1
Sterry, W1
Kaufmann, R1
Stringer, MR3
Collins, P3
Robinson, DJ3
Stables, GI3
Sheehan-Dare, RA3
Stender, IM1
Wulf, HC1
Calzavara-Pinton, PG1
Ortel, B1
Zane, C1
Wang, I1
Andersson-Engels, S1
Nilsson, GE1
Wårdell, K1
Svanberg, K1
Fritsch, C1
Lehmann, P1
Stahl, W1
Schulte, KW1
Blohm, E1
Lang, K1
Sies, H1
Ruzicka, T1
Vernon, DI1
Brown, SB1
Zeng, H1
McLean, DI1
Korbelik, M1
Wang, Y1
Fu, S1
Lu, Y1
Lai, R1
Liu, Z1
Luo, W1
Xu, Y1

Reviews

9 reviews available for aminolevulinic acid and Psoriasis

ArticleYear
Photodynamic therapy in dermatology beyond non-melanoma cancer: An update.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 19

    Topics: Acne Vulgaris; Aminolevulinic Acid; Collagen; Humans; Photochemotherapy; Photosensitizing Agents; Po

2017
Photodynamic therapy for psoriasis.
    The Journal of dermatological treatment, 2015, Volume: 26, Issue:3

    Topics: Aminolevulinic Acid; Anthracenes; Humans; Perylene; Photochemotherapy; Photosensitizing Agents; Porp

2015
Photodynamic therapy: current evidence and applications in dermatology.
    Seminars in cutaneous medicine and surgery, 2011, Volume: 30, Issue:4

    Topics: Acne Vulgaris; Aminolevulinic Acid; Bowen's Disease; Candidiasis; Carcinoma, Basal Cell; Humans; Ker

2011
Photodynamic therapy of dermatoses other than non-melanoma skin cancer.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Humans; Keratosis; Photochemotherapy; Photosensitizing

2005
Photodynamic therapy for psoriasis?
    The Australasian journal of dermatology, 1996, Volume: 37, Issue:2

    Topics: Aminolevulinic Acid; Humans; Neoplasms; Photochemotherapy; Psoriasis; Radiation-Sensitizing Agents;

1996
Photodynamic therapy with systemic administration of photosensitizers in dermatology.
    Journal of photochemistry and photobiology. B, Biology, 1996, Volume: 36, Issue:2

    Topics: Aminolevulinic Acid; Bowen's Disease; Breast Neoplasms; Dermatology; Dihematoporphyrin Ether; Female

1996
Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of delta-aminolaevulinic acid.
    British journal of cancer, 1999, Volume: 79, Issue:9-10

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Human

1999
Topical 5-aminolaevulinic acid photodynamic therapy for the treatment of skin conditions other than non-melanoma skin cancer.
    The British journal of dermatology, 2002, Volume: 146, Issue:2

    Topics: Acne Vulgaris; Aminolevulinic Acid; Humans; Lymphoma, T-Cell; Photochemotherapy; Photosensitizing Ag

2002
Non-oncologic indications for ALA-PDT.
    The Journal of dermatological treatment, 2002, Volume: 13 Suppl 1

    Topics: Aminolevulinic Acid; Humans; Lichen Sclerosus et Atrophicus; Papillomavirus Infections; Photochemoth

2002

Trials

8 trials available for aminolevulinic acid and Psoriasis

ArticleYear
Systemic photodynamic therapy with aminolevulinic acid induces apoptosis in lesional T lymphocytes of psoriatic plaques.
    The Journal of investigative dermatology, 2002, Volume: 119, Issue:1

    Topics: Administration, Oral; Aminolevulinic Acid; Apoptosis; CD3 Complex; Epidermis; Erythema; Humans; Phot

2002
Topical aminolaevulinic acid-based photodynamic therapy as a treatment option for psoriasis? Results of a randomized, observer-blinded study.
    The British journal of dermatology, 2005, Volume: 152, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Chronic Disease; Female; Humans; Male; Middle A

2005
Clinical and immunohistochemical evaluation of psoriatic plaques treated with topical 5-aminolaevulinic acid photodynamic therapy.
    Photodermatology, photoimmunology & photomedicine, 2005, Volume: 21, Issue:6

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Epidermis; Evaluation

2005
A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis.
    The British journal of dermatology, 2006, Volume: 155, Issue:2

    Topics: Adult; Aminolevulinic Acid; Cell Differentiation; Cell Proliferation; Dose Fractionation, Radiation;

2006
Disappointing results and low tolerability of photodynamic therapy with topical 5-aminolaevulinic acid in psoriasis. A randomized, double-blind phase I/II study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:7

    Topics: Administration, Topical; Adult; Aminolevulinic Acid; Chronic Disease; Double-Blind Method; Female; H

2006
Superficial blood flow following photodynamic therapy of malignant non-melanoma skin tumours measured by laser Doppler perfusion imaging.
    The British journal of dermatology, 1997, Volume: 136, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Female;

1997
The variable response of plaque psoriasis after a single treatment with topical 5-aminolaevulinic acid photodynamic therapy.
    The British journal of dermatology, 1997, Volume: 137, Issue:5

    Topics: Aminolevulinic Acid; Chronic Disease; Dose-Response Relationship, Radiation; Humans; Photochemothera

1997
Improved response of plaque psoriasis after multiple treatments with topical 5-aminolaevulinic acid photodynamic therapy.
    Acta dermato-venereologica, 1999, Volume: 79, Issue:6

    Topics: Administration, Topical; Aminolevulinic Acid; Drug Administration Schedule; Female; Follow-Up Studie

1999

Other Studies

20 other studies available for aminolevulinic acid and Psoriasis

ArticleYear
Systemic ALA-PDT effectively blocks the development of psoriasis-like lesions and alleviates leucocyte infiltration in the K14-VEGF transgenic mouse.
    Clinical and experimental dermatology, 2017, Volume: 42, Issue:8

    Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Immunohistochemistry; Interferons; Interleukin

2017
Photodynamic therapy with 5-aminolevulinic acid suppresses IFN-γ-induced K17 expression in HaCaT cells via MAPK pathway.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:20

    Topics: Aminolevulinic Acid; Apoptosis; Calcitriol; Caspase 3; Cell Line; Cell Survival; Extracellular Signa

2017
ALA-PDT alleviates the psoriasis by inhibiting JAK signalling pathway.
    Experimental dermatology, 2019, Volume: 28, Issue:11

    Topics: Aminolevulinic Acid; Animals; Drug Evaluation, Preclinical; Female; Imiquimod; Interferon-gamma; Jan

2019
Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Aminolevulinic Acid; Aminoquinolines; Animals; Cytokines; Disease Models, Animal; Female; Imiquimod;

2015
Update on new drugs in dermatology.
    Cutis, 2016, Volume: 98, Issue:5

    Topics: Aminolevulinic Acid; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agent

2016
Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells.
    The British journal of dermatology, 2009, Volume: 160, Issue:4

    Topics: Administration, Topical; Aminolevulinic Acid; Humans; Keratosis, Actinic; Photochemotherapy; Photose

2009
Pulsed dye laser vs. photodynamic therapy in the treatment of refractory nail psoriasis: a comparative pilot study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:8

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Lasers, Dye; Male; Middle Aged; Nail Diseases; Pho

2009
Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behavior.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2009, Volume: 73, Issue:3

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Chemistry, Pharmaceutical; Disease Models,

2009
The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis.
    The Journal of dermatological treatment, 2010, Volume: 21, Issue:4

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Analysis of Variance; Bandages, Hydrocolloid; Bi

2010
[Therapeutic effect of photodynamic treatment for psoriasis vulgaris in guinea pigs].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:5

    Topics: Acne Vulgaris; Aminolevulinic Acid; Animals; Guinea Pigs; Photochemotherapy; Photosensitizing Agents

2011
Lack of efficacy and tolerability of topical PDT for psoriasis in comparison with narrowband UVB phototherapy.
    Clinical and experimental dermatology, 2004, Volume: 29, Issue:5

    Topics: Administration, Topical; Aminolevulinic Acid; Humans; Photochemotherapy; Photosensitizing Agents; Ps

2004
Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid.
    The Journal of investigative dermatology, 2005, Volume: 125, Issue:4

    Topics: Aminolevulinic Acid; DNA; Humans; Keratosis; Protoporphyrins; Psoriasis; Spectrometry, Fluorescence

2005
Recalcitrant palmoplantar pustular psoriasis successfully treated with topical 5-aminolaevulinic acid photodynamic therapy.
    Clinical and experimental dermatology, 2005, Volume: 30, Issue:6

    Topics: Adult; Aminolevulinic Acid; Chronic Disease; Dose-Response Relationship, Radiation; Female; Humans;

2005
Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study.
    The British journal of dermatology, 2006, Volume: 155, Issue:3

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Biopsy; Cell Differentiation; Cell Proliferati

2006
Topical 5-aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis.
    The Journal of dermatology, 2007, Volume: 34, Issue:1

    Topics: Adult; Aminolevulinic Acid; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Aged; Photochemot

2007
Treatment of psoriasis by topical photodynamic therapy with polychromatic light.
    Lancet (London, England), 1994, Mar-26, Volume: 343, Issue:8900

    Topics: Administration, Topical; Aminolevulinic Acid; Anthralin; Chronic Disease; Follow-Up Studies; Humans;

1994
The accumulation of protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:1

    Topics: Administration, Topical; Aminolevulinic Acid; Dose-Response Relationship, Drug; Humans; Photochemoth

1996
Købner reaction induced by photodynamic therapy using delta-aminolevulinic acid. A case report.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Photochemotherapy; Psoriasis; Recurren

1996
Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:2

    Topics: Administration, Oral; Aminolevulinic Acid; Blood Cells; Fluorescence; Humans; Photochemotherapy; Pho

2001
Chitosan/hyaluronan nanogels co-delivering methotrexate and 5-aminolevulinic acid: A combined chemo-photodynamic therapy for psoriasis.
    Carbohydrate polymers, 2022, Feb-01, Volume: 277

    Topics: Aminolevulinic Acid; Cell Line; Chitosan; Drug Therapy, Combination; Humans; Hyaluronic Acid; Levuli

2022