Page last updated: 2024-11-04

vorinostat and Psoriasis

vorinostat has been researched along with Psoriasis in 1 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Our results support the notion that vorinostat, a prototypic HDAC inhibitor, may be of potential use in the treatment of psoriasis and other hyperproliferative skin disorders."8.12Vorinostat, a histone deacetylase inhibitor, as a potential novel treatment for psoriasis. ( Bochner, R; Fuchs-Telem, D; Gilhar, A; Keren, A; Magal, L; Malovitski, K; Nousbeck, J; Sagiv, N; Samuelov, L; Sarig, O; Sprecher, E, 2022)
"Our results support the notion that vorinostat, a prototypic HDAC inhibitor, may be of potential use in the treatment of psoriasis and other hyperproliferative skin disorders."4.12Vorinostat, a histone deacetylase inhibitor, as a potential novel treatment for psoriasis. ( Bochner, R; Fuchs-Telem, D; Gilhar, A; Keren, A; Magal, L; Malovitski, K; Nousbeck, J; Sagiv, N; Samuelov, L; Sarig, O; Sprecher, E, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Samuelov, L1
Bochner, R1
Magal, L1
Malovitski, K1
Sagiv, N1
Nousbeck, J1
Keren, A1
Fuchs-Telem, D1
Sarig, O1
Gilhar, A1
Sprecher, E1

Other Studies

1 other study available for vorinostat and Psoriasis

ArticleYear
Vorinostat, a histone deacetylase inhibitor, as a potential novel treatment for psoriasis.
    Experimental dermatology, 2022, Volume: 31, Issue:4

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Histone Deacetylase Inhibitors; Mice; Psor

2022