fast blue bb

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Fast Blue BB: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	67108
SCHEMBL ID	301964
MeSH ID	M0066421

Synonyms (66)

Synonym
4-benzoylamino-2,5-diethoxyaniline
spectrolene blue bb
daito blue base bb
nsc-37184
tulabase fast blue bb
c.i. azoic diazo component 20, base
blue salt nbb
blue 2b base
2-amino-5-benzoylaminohydroquinone diethyl ether
fast blue bbn
diazo fast blue bb
120-00-3
nsc37184
amarthol fast blue bb base
azoic diazo component 20, base
fast blue bb base
stabamine blue bb
naphtoelan blue bb base
2,5-diethoxy-4-benzamidoaniline
hiltonil fast blue bb base
c.i. 37175
fast blue eb base
brentamine fast blue 2b base
azoene fast blue bb base
brentamine fast blue bb base
fast blue base bb
c.i. azoic diazo component 20
sanyo fast blue bb base
OPREA1_096764
n-(4-amino-2,5-diethoxyphenyl)benzamide
fast blue bb
azoic diazo component 20 (base)
4'-amino-2',5'-diethoxybenzanilide
cnxzlzneiyfzgu-uhfffaoysa-
inchi=1/c17h20n2o3/c1-3-21-15-11-14(16(22-4-2)10-13(15)18)19-17(20)12-8-6-5-7-9-12/h5-11h,3-4,18h2,1-2h3,(h,19,20)
AKOS000120746
STK761212
nsc 37184
benzamide, n-(4-amino-2,5-diethoxyphenyl)-
benzanilide, 4'-amino-2',5'-diethoxy-
einecs 204-363-8
9fb70c7gdi ,
unii-9fb70c7gdi
ec 204-363-8
FT-0631686
azoic diazo no. 20
4-benzamido-2,5-diethoxyaniline
ci 37175
SCHEMBL301964
DTXSID8059504
n-(4-amino-2,5-diethoxyphenyl)benzamide #
CNXZLZNEIYFZGU-UHFFFAOYSA-N
fast blue bb (c.i. 37175)
mfcd00009091
sr-01000526358
J-004229
n-(4-amino-2,5-diethoxyphenyl)benzamide, dye content 90 %
SR-01000526358-1
CS-0196559
Z104484924
4-benzamido-2, 5-diethoxyaniline
AMY40949
Q27272487
D88494
4-amino-1-(benzoylamino)-3,6-diethoxybenzene
A920128

Research Excerpts

Bioavailability

Excerpt	Reference	Relevance
" Regarding the treatments, the group that received AQB showed to have increased polyphenolic bioavailability in brainstem (p<0."	( [Analysis of tissue bioavailability of total polyphenols by Folin Ciocalteu and Fast Blue BB techniques in organs of BALB/C/c mice]. Albrecht, C; Miranda, AR; Soria, EA, 2017)	0.68
"FBBB method showed higher estimations of polyphenolic bioavailability than FC, and this could be related to higher specificity of the technique to react with phenolic compounds."	( [Analysis of tissue bioavailability of total polyphenols by Folin Ciocalteu and Fast Blue BB techniques in organs of BALB/C/c mice]. Albrecht, C; Miranda, AR; Soria, EA, 2017)	0.68

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (35.29)	18.7374
1990's	4 (23.53)	18.2507
2000's	1 (5.88)	29.6817
2010's	4 (23.53)	24.3611
2020's	2 (11.76)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	35.40 (24.57)
Research Supply Index	2.94 (2.92)
Research Growth Index	5.15 (4.65)
Search Engine Demand Index	36.43 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (35.40)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	18 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
benzene [no description available]	1.95	1	aromatic annulene; benzenes; volatile organic compound	carcinogenic agent; environmental contaminant; non-polar solvent
gallic acid gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.	2.06	1	trihydroxybenzoic acid	antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	1.97	1	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
phenol [no description available]	2.06	1	phenols	antiseptic drug; disinfectant; human xenobiotic metabolite; mouse metabolite
sodium fluoride [no description available]	1.97	1	fluoride salt	mutagen
1-naphthaleneacetic acid 1-naphthaleneacetic acid: a plant growth regulator; RN given refers to parent cpd. naphthylacetic acid : A monocarboxylic acid that is naphthalene substituted by a carboxymethyl group at any position.. 1-naphthaleneacetic acid : A naphthylacetic acid substituted by a carboxymethyl group at position 1.	2.07	1	naphthylacetic acid	synthetic auxin
3,3'-diaminobenzidine 3,3'-Diaminobenzidine: A chemically and thermodynamically stable derivative of BENZIDINE.. 3,3'-diaminobenzidine : A member of the class of biphenyls that is benzidine in which one of the hydrogens ortho to each of the amino groups has been replaced by an amino group.	1.96	1	biphenyls; substituted aniline	histological dye
tolonium chloride Tolonium Chloride: A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery.. tolonium chloride : An organic chloride salt having 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium (tolonium) as the counterion. It is a blue nuclear counterstain that can be used to demonstrate Nissl substance and is also useful for staining mast cell granules, both in metachromatic and orthochromatic techniques.	1.98	1
benzidine benzidine: RN given refers to parent cpd. benzidine : A member of the class of biphenyls that is 1,1'-biphenyl in which the hydrogen at the para-position of each phenyl group has been replaced by an amino group.	1.96	1	biphenyls; substituted aniline	carcinogenic agent
o-aminoazotoluene o-Aminoazotoluene: An azo dye with carcinogenic properties.	1.98	1
3-amino-9-ethylcarbazole 3-amino-9-ethylcarbazole: RN given refers to parent cpd	1.96	1	carbazoles
2-naphthol 2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.	2.66	3	naphthol	antinematodal drug; genotoxin; human urinary metabolite; human xenobiotic metabolite; mouse metabolite; radical scavenger
c.i. 42510 Rosaniline Dyes: Compounds that contain the triphenylmethane aniline structure found in rosaniline. Many of them have a characteristic magenta color and are used as COLORING AGENTS.. basic fuchsin : A four-component mixture of chemically related dyes comprising pararosanilin, rosanilin, magenta II and new fuchsin in varying amounts. rosanilin : A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the major constituents of Basic fuchsin, together with pararosanilin, magenta II and new fuchsin.	2.37	2
molybdenum Molybdenum: A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.95. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase.	2.06	1	chromium group element atom	micronutrient
naphthol as-bi phosphate naphthol AS-BI phosphate: RN given refers to parent cpd	1.96	1
alpha-naphthyl butyrate [no description available]	2.66	3
methanesulfinic acid methanesulfinic acid: structure given in first source; RN given refers to parent cpd. methanesulfinic acid : An organosulfinic acid that is methane in which one of the hydrogens has been replaced by a sulfino group.	1.97	1	organosulfinic acid
naphthol as-d chloroacetate [no description available]	1.96	1
diethylstilbestrol Diethylstilbestrol: A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed). diethylstilbestrol : An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.	1.98	1	olefinic compound; polyphenol	antifungal agent; antineoplastic agent; autophagy inducer; calcium channel blocker; carcinogenic agent; EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; endocrine disruptor; xenoestrogen
zeranol Zeranol: A non-steroidal estrogen analog.	1.98	1	macrolide
aluminum oxide Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.	1.98	1
acid phosphatase Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.	1.96	1
new fuchsin new fuchsin : A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the minor constituents of Basic fuchsin, together with pararosanilin, rosanilin and magenta II.	1.96	1	hydrochloride	fluorochrome; histological dye

Condition	Relationship Strength	Studies
Acute Myelogenous Leukemia [description not available]	1.96	1
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.	1.96	1
Leukemic Infiltration A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.	1.98	1
Eczema, Atopic [description not available]	1.98	1
Lichen Ruber Planus [description not available]	1.98	1
Palmoplantaris Pustulosis [description not available]	1.98	1
B-Cell Chronic Lymphocytic Leukemia [description not available]	1.98	1
Dermatitis, Atopic A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.	1.98	1
Lichen Planus An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.	1.98	1
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.	1.98	1
Leukemia, Lymphocytic, Chronic, B-Cell A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.	1.98	1
Cancer of Colon [description not available]	1.97	1
Leucocythaemia [description not available]	1.97	1
Colonic Neoplasms Tumors or cancer of the COLON.	1.97	1
Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)	1.97	1

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