tetradecanoylphorbol acetate has been researched along with Psoriasis in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (18.31) | 18.7374 |
| 1990's | 16 (22.54) | 18.2507 |
| 2000's | 12 (16.90) | 29.6817 |
| 2010's | 26 (36.62) | 24.3611 |
| 2020's | 4 (5.63) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, Y; Kiyoi, T; Kondo, H; Kurokawa, K; Nakada, Y; Nakajima, F; Sawa, M; Tsukamoto, T; Yokota, K; Yoshino, K | 1 |
| Bocheńska, K; Gabig-Cimińska, M; Moskot, M | 1 |
| Collado-Diaz, V; Friess, MC; Hagedorn, O; Haghayegh Jahromi, N; Halin, C; Jadhav, M; Leroux, JC; Polomska, A; Proulx, ST; Vallone, A; Vranova, M; Willrodt, AH | 1 |
| Diez-Sales, O; Escribano-Ferrer, E; Manca, ML; Manconi, M; Nácher, A; Pleguezuelos-Villa, M; Sauri, AR | 1 |
| Balkrishna, A; Chauhan, A; Gupta, A; Nain, P; Ranjan, R; Sharma, N; Varshney, A | 1 |
| Evan Prince, S; Hiraganahalli Bhaskarmurthy, D | 1 |
| Enk, AH; Hadaschik, EN; Hartl, D; Hoffmann, JHO; Schaekel, K | 1 |
| Ando, H; Fujimura, A; Kumazaki, M; Ushijima, K; Yoshioka, D | 1 |
| Bigas, J; Boix, J; Carceller, E; Pérez, P; Sevilla, LM | 1 |
| Ho, CT; Li, S; Lin, CC; Wang, P; Yang, G; Yang, Y; Yuan, L; Zhao, H | 1 |
| Kataoka, S; Nakajima, K; Ohko, K; Sano, S; Takaishi, M | 1 |
| Furue, Y; Imura, C; Katayama, K; Okuno, T; Sasaki, Y; Shichijo, M; Shimizu, M; Tai, N; Tsujii, K; Ueyama, A; Yamamoto, M; Yasui, K | 1 |
| Chen, HX; Dong, CZ; Du, ZY; Gu, YH; Li, PH; Zhang, WJ; Zhao, MC | 1 |
| Diboll, J; Faini, D; Fullard, N; Mann, DA; Moles, A; O'Reilly, S; Oakley, F; Reichelt, J; Reynolds, NJ; van Laar, JM | 1 |
| Jung, YG; Kim, BH; Kim, S; Kim, TY; Lee, JM | 1 |
| Caughey, GE; Claudie, DJ; Costabile, M; Luo, X; McKinnon, RA; Semple, SJ; Simpson, BS; Wang, J | 1 |
| Kataoka, S; Kitaba, S; Magata, Y; Nakajima, K; Sano, S; Takaishi, M; Yamamoto, M | 1 |
| Jaji, MS; Krishnan, UM; Kulkarni, NM; Mookkan, J; Muley, MM; Narayanan, S; Raghul, J; Rajesh, NB; Reddy, NK; Vijaykanth, G; Vishwakarma, SL | 1 |
| Sano, S; Sato, K; Takaishi, M; Tokuoka, S | 1 |
| Cao, J; Chen, A; Huang, K; Song, Z; Xu, H; Yin, Y; Zhang, X | 1 |
| Hu, J; Jin, H; Sun, J; Zhao, Y | 1 |
| Bao, YL; Huang, YX; Li, WL; Li, YX; Song, ZB; Sun, LG; Wang, Q; Yang, XG; Yu, CL; Zhang, WJ | 1 |
| Aarup, A; Christensen, JP; Hansen, PR; Hartvigsen, K; Madsen, M; Nielsen, LB; Pedersen, AE; Pedersen, TX | 1 |
| Ishizaki, M; Isobe, T; Sano, S; Shimozato, T; Suzuki, K; Takaishi, M | 1 |
| Aoki, M; Furue, Y; Fusamae, Y; Imura, C; Okuda, T; Oshima, I; Shichijo, M; Suzuki, M; Tsujii, K; Ueyama, A; Yamamoto, M; Yasui, K | 1 |
| Brito, PS; Cabrini, DA; Facundo, VA; Favero, GM; Horinouchi, CD; Mendes, DA; Nolte, S; Otuki, MF; Santos, AR; Soley, BD | 1 |
| Higaki, M; Higaki, Y; Kawashima, M | 1 |
| Fukuda, Y; Goto, M; Hayashi, Y; Inoue, H; Kadoshima-Yamaoka, K; Kanki, S; Murafuji, H; Murakawa, M; Nagahira, K; Nakatsuka, T; Ogata, A; Tanaka, Y; Yoshioka, R | 1 |
| Chiba, K; Goto, M; Gusovsky, F; Inoue, Y; Ishii, N; Kuboi, Y; Muramoto, K; Omae, T; Shirota, H; Wang, YJ | 1 |
| Benson, JM; DiGiovanni, J; Elloso, MM; Gutshall, LL; Iwakura, Y; Kamijima, R; Kanda, T; Miyoshi, K; Nakajima, H; Nakajima, K; Naso, MF; Sano, S; Shiga, T; Takaishi, M; Tarutani, M | 1 |
| Alves-Filho, JC; Asquith, DL; Graham, GJ; Hueber, AJ; Liew, FY; McInnes, IB; Michels, C; Millar, NL; Miller, AM; Reilly, JH | 1 |
| Dziarski, R; Gupta, D; Hurwich, R; Kim, CH; Park, SY | 1 |
| Bacon, P; Cesnjaj, M; Chaturvedi, V; Choubey, D; Diaz, MO; Nickoloff, BJ; Panella, J | 1 |
| Iizuka, H; Itoh, Y; Nakajima, S; Sakata, I; Takahashi, H | 1 |
| Jetten, AM; Kim, YS; Nakajima, T; Nakanishi, G | 1 |
| Oliw, EH; Stark, K; Törmä, H | 1 |
| Bando, Y; Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Jiang, YP; Kishibe, M; Mitrovic, B; Namikawa, K; Perez, D; Takahashi, H; Terayama, R; Yoshida, S | 1 |
| Elomaa, O; Forsberg, S; Kainu, K; Kere, J; Puolakkainen, P; Rollman, O; Rozell, B; Saarialho-Kere, U; Suomela, S; Tammi, R; Tiala, I; Wakkinen, J | 1 |
| Amigó, M; Braza-Boïls, A; De Rosa, S; Payá, M; Terencio, MC | 1 |
| Chang, S; Demerjian, M; Elias, PM; Feingold, KR; Lee, SH; Man, M; Man, MQ; Shi, Y | 1 |
| Coble, BI; Dahlgren, C; Hed, J; Molin, L; Stendahl, O | 1 |
| Bourin, MC; Delescluse, C; Pruniéras, M | 1 |
| Christophers, E; Koh, CJ; Schröder, JM; Szperalski, B | 1 |
| Emilson, A; Fransson, J; Hammar, H; Scheynius, A | 1 |
| Baron, DA; Fretland, DJ; Gokhale, R; Mathur, L; Paulson, SK; Stolzenbach, J | 1 |
| Asagami, C; Hamamoto, Y; Muto, M; Nagai, K | 1 |
| Celis, JE; Rasmussen, HH | 1 |
| Kiyoki, M; Matsunaga, T; Ohta, T; Sato, H; Sugimoto, I; Tsuchimoto, M; Uno, H | 1 |
| Cohen, S; Eitan, A; Gilhar, A; Grossman, N; Kahanovicz, S; Reuveni, H | 1 |
| Borgers, M; Geysen, J; Janssens, S; Vandermeeren, M | 1 |
| Cardinale, I; Finch, PW; Krueger, JG; Murphy, F | 1 |
| Austin, LM; Kikuchi, T; Krueger, JG; Ozawa, M; Walters, IB | 1 |
| Ansel, JC; Burbach, GJ; Cannon, G; Caughman, SW; Naik, SM; Singh, SR; Swerlick, RA; Wilcox, JN | 1 |
| Chinni, LM; De Pità, O; Frezzolini, A; Giannetti, A; Girolomoni, G; Giustizieri, ML; Mascia, F; Pastore, S | 1 |
| Al-Daraji, WI; Grant, KR; Reynolds, NJ; Ryan, K; Saxton, A | 1 |
| Carter, DM; Gottlieb, AB; Krane, JF; Krueger, JG | 1 |
| Fruchtmann, R; Hegemann, L; Mahrle, G; Müller-Peddinghaus, R; van Rooijen, LA | 1 |
| Ito, K; Namikawa, S; Takeuchi, K | 1 |
| Barker, JN; Crockett-Torabe, E; Dixit, VM; Fantone, JC; Jones, ML; Kunkel, SL; Mitra, RS; Nickoloff, BJ; Warren, JS | 1 |
| Djuric, SW; Fretland, DJ; Gaginella, TS; Levin, S; Shone, RL; Tsai, BS; Walsh, RE; Widomski, DL; Zemaitis, JM | 1 |
| Baldassare, JJ; Fisher, GJ; Henderson, PA; Talwar, HS; Voorhees, JJ | 1 |
| Kapp, A; Schöpf, E | 1 |
| Coble, BI; Dahlgren, C; Molin, L; Stendahl, O | 1 |
| Abidi, TF; Laskin, JD; Mermelstein, FH | 1 |
| Cerimele, D; De Simone, C; De Sole, P; Di Mario, G; Serri, F; Venier, A | 1 |
| Battoccoli, E; Marchiseppe, I; Offidani, AM; Simonetti, O; Tappa, MM; Valentino, M | 1 |
| Basset-Seguin, N; Bonne, C; Guilhou, JJ; Junquero, D; Levy, C; Modat, G | 1 |
| Amdahl, LD; De Vries, GW; Lowe, N; Wheeler, LA | 1 |
| Fisher, GJ; Horn, F; Marks, F; Voorhees, JJ | 1 |
| Schopf, RE; Straussfeld, E | 1 |
| Morsches, B; Schopf, RE; Straussfeld, E | 1 |
71 other study(ies) available for tetradecanoylphorbol acetate and Psoriasis
| Article | Year |
|---|---|
New strategy for antedrug application: development of metalloproteinase inhibitors as antipsoriatic drugs.
Topics: Amphiregulin; Animals; Cell Line; Disease Models, Animal; Drug Stability; EGF Family of Proteins; Epidermal Growth Factor; Glycoproteins; Growth Substances; Heparin-binding EGF-like Growth Factor; Humans; Hydroxylamines; Hyperplasia; Intercellular Signaling Peptides and Proteins; Isoquinolines; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Protease Inhibitors; Psoriasis; Recombinant Proteins; Skin; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines | 2002 |
Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models.
Topics: Adult; Cells, Cultured; Coculture Techniques; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Genetic Markers; HaCaT Cells; Humans; Imiquimod; Inflammation; Interferon-gamma; Keratinocytes; Lipopolysaccharides; Models, Biological; Psoriasis; RNA, Messenger; Serum; Tetradecanoylphorbol Acetate | 2021 |
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.
Topics: Animals; Antibodies, Neutralizing; CD4-Positive T-Lymphocytes; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-7; Lymph Nodes; Lymphatic Vessels; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Oxazolone; Psoriasis; Receptors, Interleukin-7; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2019 |
Mangiferin glycethosomes as a new potential adjuvant for the treatment of psoriasis.
Topics: 3T3 Cells; Adjuvants, Pharmaceutic; Administration, Cutaneous; Animals; Disease Models, Animal; Drug Carriers; Drug Compounding; Epidermis; Ethanol; Female; Glycerol; Humans; Hydrogen Peroxide; Mangifera; Mice; Phospholipids; Psoriasis; Tetradecanoylphorbol Acetate; Tissue Distribution; Wound Healing; Xanthones | 2020 |
Super Critical Fluid Extracted Fatty Acids from
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Mice; Psoriasis; RAW 264.7 Cells; Seeds; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Withania | 2020 |
Effect of Baricitinib on TPA-induced psoriasis like skin inflammation.
Topics: Administration, Topical; Animals; Azetidines; Carcinogens; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Purines; Pyrazoles; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 2021 |
Dimethyl fumarate modulates neutrophil extracellular trap formation in a glutathione- and superoxide-dependent manner.
Topics: Analysis of Variance; Antioxidants; Caspases; Cells, Cultured; Dermatologic Agents; Dimethyl Fumarate; Dose-Response Relationship, Drug; Extracellular Traps; Fumarates; Glutathione; GTP-Binding Proteins; Humans; Ionomycin; Platelet Activating Factor; Psoriasis; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate | 2018 |
Chronotherapy of maxacalcitol on skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate in mice.
Topics: Animals; Calcitriol; Chronotherapy; Circadian Rhythm; Inflammation; Male; Mice; Mice, Inbred C57BL; Psoriasis; Receptors, Calcitriol; Skin; Tetradecanoylphorbol Acetate | 2018 |
Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation.
Topics: Animals; Cell Differentiation; Cell Proliferation; Epidermis; Gene Expression Regulation; Glucocorticoids; Imiquimod; Inflammation; Keratinocytes; Mice, Knockout; NF-kappa B; Phenotype; Phosphorylation; Psoriasis; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by Regulating the Expression of Ki-67 and Proliferating Cell Nuclear Antigen and the Differentiation of CD4
Topics: Animals; CD4-Positive T-Lymphocytes; Citrus; Female; Flavones; Fruit; Gene Expression; Ki-67 Antigen; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Proliferating Cell Nuclear Antigen; Psoriasis; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
IL-36 Signaling Is Essential for Psoriatic Inflammation through the Augmentation of Innate Immune Responses.
Topics: Adult; Aged; Animals; Disease Models, Animal; Female; Gene Knockout Techniques; Humans; Immunity, Innate; Interleukin-1; Male; Mice, Knockout; Middle Aged; Psoriasis; Receptors, Interleukin-1; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2019 |
A novel RORγt inhibitor is a potential therapeutic agent for the topical treatment of psoriasis with low risk of thymic aberrations.
Topics: Administration, Cutaneous; Animals; Cells, Cultured; Dermatologic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Healthy Volunteers; Humans; Immunity, Innate; Interleukin-17; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Primary Cell Culture; Psoriasis; Severity of Illness Index; Skin; Sulfones; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Treatment Outcome | 2019 |
Synthesis and identification of quinoline derivatives as topoisomerase I inhibitors with potent antipsoriasis activity in an animal model.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Ear; Imiquimod; Inflammation; Male; Mice, Inbred BALB C; Psoriasis; Quinolines; Skin; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 2019 |
The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.
Topics: Animals; Bleomycin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Epidermis; Fibrosis; Homeostasis; Humans; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; Proto-Oncogene Proteins c-rel; Psoriasis; Scleroderma, Systemic; Skin; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Wound Healing | 2013 |
Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-κB and JAK/STAT signaling in keratinocytes and mice.
Topics: Adult; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Dermatitis; Humans; Inflammation; Interleukin-23; Janus Kinase 1; Keratinocytes; Leukocytes, Mononuclear; Male; MAP Kinase Signaling System; Mice; NF-kappa B; Psoriasis; Signal Transduction; Skin; Sphingosine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Polyandric acid A, a clerodane diterpenoid from the Australian medicinal plant Dodonaea polyandra, attenuates pro-inflammatory cytokine secretion in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Australia; Cytokines; Disease Models, Animal; Diterpenes, Clerodane; Ear; Edema; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Molecular Structure; Nitric Oxide; Peroxidase; Plants, Medicinal; Psoriasis; Sapindaceae; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Psoriatic inflammation facilitates the onset of arthritis in a mouse model.
Topics: Animals; Arthritis, Psoriatic; Cytokines; Disease Models, Animal; Inflammation; Joint Diseases; Mice; Mice, Inbred C57BL; Psoriasis; Skin Diseases; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Th17 Cells | 2015 |
Topical atorvastatin ameliorates 12-O-tetradecanoylphorbol-13-acetate induced skin inflammation by reducing cutaneous cytokine levels and NF-κB activation.
Topics: Animals; Atorvastatin; Cell Proliferation; Cytokines; Dermatitis; Dose-Response Relationship, Drug; Ear, External; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Peroxidase; Psoriasis; Skin; Tetradecanoylphorbol Acetate | 2015 |
Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in a mouse model.
Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Animals; Disease Models, Animal; EGF Family of Proteins; Gene Expression Regulation; Humans; Mice; Psoriasis; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation.
Topics: Adult; Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; Female; Gene Expression Regulation; Granulins; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Middle Aged; Progranulins; Psoriasis; Skin; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2015 |
Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice.
Topics: Animals; Anti-Inflammatory Agents; Curcumin; Cytokines; Disease Models, Animal; Gels; Inflammation; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Receptors, CCR6; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Th1 Cells | 2015 |
Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models.
Topics: Aminoquinolines; Animals; Cell Death; Cell Line; Cell Survival; Digitoxigenin; Disease Models, Animal; Female; Humans; Imiquimod; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Psoriasis; Tetradecanoylphorbol Acetate | 2016 |
Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carcinogens; Cytokines; Disease Models, Animal; Hypercholesterolemia; Inflammation; Mice; Mice, Transgenic; Psoriasis; RNA, Messenger; Serum Amyloid A Protein; Spleen; Tetradecanoylphorbol Acetate | 2016 |
Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17.
Topics: Administration, Oral; Animals; Cell Differentiation; Cell Line, Tumor; Disease Models, Animal; Humans; Interleukin-17; Interleukin-23; Mice; Mice, Inbred BALB C; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Interleukin-17; Signal Transduction; Skin; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Th17 Cells | 2017 |
Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model.
Topics: Animals; CD4 Antigens; CD8 Antigens; Disease Models, Animal; Flow Cytometry; Humans; Immunohistochemistry; Inflammation; Interleukin-17; Interleukin-23 Subunit p19; Mice; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, CCR6; Skin; STAT3 Transcription Factor; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2017 |
Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Chronic Disease; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Hormone Antagonists; Humans; Keratinocytes; Mice; Mifepristone; Proliferating Cell Nuclear Antigen; Psoriasis; Receptors, Glucocorticoid; Skin; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2017 |
Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesions.
Topics: Adult; Antigen-Presenting Cells; Antigens, CD; Antigens, CD1; Case-Control Studies; CD83 Antigen; Cell Adhesion Molecules; Cell Differentiation; Cells, Cultured; Female; HLA-DR Antigens; Humans; Immunoglobulins; Immunohistochemistry; Interferon-gamma; Keratinocytes; Lectins, C-Type; Lysosomal Membrane Proteins; Male; Mannose-Binding Lectins; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Psoriasis; Receptors, Cell Surface; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2009 |
Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.
Topics: Administration, Cutaneous; Animals; Bucladesine; Cell Proliferation; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease Models, Animal; Epidermis; Female; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Phosphodiesterase Inhibitors; Psoriasis; Pyrazoles; Skin; Tetradecanoylphorbol Acetate; Thiophenes | 2010 |
E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory respon
Topics: Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Croton Oil; Dinitrofluorobenzene; Diterpenes; Drug Eruptions; Hyperplasia; Indicators and Reagents; Interleukin-17; Interleukin-23; Lactones; Male; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Ornithine Decarboxylase; Peroxidase; Protein Kinase Inhibitors; Psoriasis; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2010 |
Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model.
Topics: Animals; beta-Defensins; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Immunization, Passive; Immunophenotyping; Interleukin-17; Interleukin-23; Killer Cells, Natural; Male; Mice; Mice, Transgenic; NIH 3T3 Cells; Psoriasis; S100 Proteins; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2011 |
IL-33 induces skin inflammation with mast cell and neutrophil activation.
Topics: Animals; Chemokine CXCL1; Dermatitis; Flow Cytometry; Humans; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Interleukins; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; Psoriasis; Receptors, Interleukin; Skin; Tetradecanoylphorbol Acetate | 2011 |
Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses.
Topics: Animals; Carcinogens; Cell Separation; Disease Models, Animal; Flow Cytometry; Mice; Mice, Inbred BALB C; Mice, Knockout; N-Acetylmuramoyl-L-alanine Amidase; Proteins; Psoriasis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th17 Cells | 2011 |
Role of INK4a/Arf locus-encoded senescent checkpoints activated in normal and psoriatic keratinocytes.
Topics: Cell Division; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cytokines; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Gene Expression Regulation; Genes, cdc; Genes, Reporter; Humans; Immediate-Early Proteins; Keratinocytes; Methylcellulose; Mitogen-Activated Protein Kinases; Psoriasis; ras Proteins; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Suppressor Protein p14ARF | 2003 |
A novel ATX-S10(Na) photodynamic therapy for human skin tumors and benign hyperproliferative skin.
Topics: Animals; Bowen's Disease; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Humans; Laser Therapy; Mice; Mice, Hairless; Mice, Inbred BALB C; Mice, SCID; Neoplasm Transplantation; Ointments; Photochemotherapy; Porphyrins; Psoriasis; Radiation-Sensitizing Agents; Skin; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 2004 |
Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.
Topics: Animals; Cell Differentiation; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA-Binding Proteins; Epidermal Cells; Epidermis; Gene Expression Profiling; Gene Expression Regulation; Humans; Interferon-gamma; Keratinocytes; Mice; Mutation; Psoriasis; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors | 2006 |
Co-localization of COX-2, CYP4F8, and mPGES-1 in epidermis with prominent expression of CYP4F8 mRNA in psoriatic lesions.
Topics: Aryl Hydrocarbon Hydroxylases; Carcinogens; Cell Line; Cyclooxygenase 2; Cytokines; Epidermis; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Intramolecular Oxidoreductases; Keratinocytes; Membrane Proteins; Prostaglandin-E Synthases; Psoriasis; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins.
Topics: Animals; Cell Differentiation; Cell Proliferation; Dermis; Desmoglein 1; Disease Models, Animal; Humans; Kallikreins; Keratinocytes; Mice; Mice, Knockout; Psoriasis; Tetradecanoylphorbol Acetate | 2007 |
The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.
Topics: Animals; Cell Movement; Cell Proliferation; Hyperplasia; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Transgenic; Psoriasis; Tetradecanoylphorbol Acetate; Wound Healing | 2008 |
Avarol inhibits TNF-alpha generation and NF-kappaB activation in human cells and in animal models.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Humans; Hyperplasia; Inflammation; Inflammation Mediators; Keratinocytes; Mice; Monocytes; NF-kappa B p50 Subunit; Peroxidase; Psoriasis; Sesquiterpenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Dermatitis, Allergic Contact; Dermatitis, Contact; Disease Models, Animal; Drugs, Chinese Herbal; Fabaceae; Female; Glycyrrhiza; Humans; Hyperplasia; Male; Mice; Mice, Hairless; Oxazolone; Phytotherapy; Psoriasis; Skin; Smilax; Tetradecanoylphorbol Acetate | 2008 |
Myeloperoxidase modulates the phagocytic activity of polymorphonuclear neutrophil leukocytes. Studies with cells from a myeloperoxidase-deficient patient.
Topics: Complement C3b; Humans; Immunoglobulin G; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peroxidase; Peroxidases; Phagocytosis; Psoriasis; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Hyperplasia and tumor promotion.
Topics: Animals; Croton Oil; Guinea Pigs; Humans; Hyperplasia; Mice; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Prostaglandins E; Psoriasis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
IgA-associated inhibition of polymorphonuclear leukocyte chemotaxis in neutrophilic dermatoses.
Topics: Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Dermatitis; Female; Humans; Immunoglobulin A; Male; Middle Aged; Neutrophils; Psoriasis; Tetradecanoylphorbol Acetate | 1981 |
Proliferation and interferon-gamma receptor expression in psoriatic and healthy keratinocytes are influenced by interactions between keratinocytes and fibroblasts in a skin equivalent model.
Topics: Adult; Cell Differentiation; Cell Division; Cells, Cultured; Fibroblasts; Filaggrin Proteins; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Keratinocytes; Middle Aged; Psoriasis; Receptors, Interferon; Tetradecanoylphorbol Acetate | 1995 |
Dermal inflammation in primates, mice, and guinea pigs: attenuation by second-generation leukotriene B4 receptor antagonist, SC-53228.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Disease Models, Animal; Drug Eruptions; Drug Evaluation, Preclinical; Ear, External; Edema; Female; Gels; Guinea Pigs; Humans; Male; Mice; Peroxidase; Psoriasis; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate | 1995 |
Inhibitory effect of azelastine, a potent antiallergic agent, on release of tumor necrosis factor-alpha from activated human peripheral blood mononuclear cells and U937 cells.
Topics: Depression, Chemical; Dermatitis, Atopic; Humans; Monocytes; Neoplasm Proteins; Phthalazines; Phytohemagglutinins; Psoriasis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Evidence for an altered protein kinase C (PKC) signaling pathway in psoriasis.
Topics: Alkaloids; Cells, Cultured; Fluorometry; Humans; Isoelectric Focusing; Keratinocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Psoriasis; Reference Values; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Tacalcitol (1,24(OH)2D3, TV-02) inhibits phorbol ester-induced epidermal proliferation and cutaneous inflammation, and induces epidermal differentiation in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Calcium; Cell Differentiation; Cell Division; Dermatitis; Dihydroxycholecalciferols; DNA; Enzyme Induction; Enzyme Inhibitors; Epidermal Cells; Epidermis; Female; Mice; Mice, Hairless; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Psoriasis; Tetradecanoylphorbol Acetate; Transglutaminases | 1996 |
Antiproliferative effect of pentoxifylline on psoriatic and normal epidermis. In vitro and in vivo studies.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinogens; Epidermal Cells; Epidermis; Female; Humans; In Vitro Techniques; Male; Mice; Mice, Nude; Middle Aged; Pentoxifylline; Psoriasis; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Vasodilator Agents | 1996 |
Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.
Topics: Blotting, Northern; Cell Adhesion; Cell Adhesion Molecules; Cytokines; Dimethyl Fumarate; E-Selectin; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Fumarates; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interleukins; Lipopolysaccharides; Psoriasis; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Cord; Vascular Cell Adhesion Molecule-1 | 1997 |
Altered expression of keratinocyte growth factor and its receptor in psoriasis.
Topics: Cells, Cultured; Cytokines; Down-Regulation; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression; Growth Substances; Humans; Immunoenzyme Techniques; In Situ Hybridization; Keratinocytes; Psoriasis; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; RNA, Messenger; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1997 |
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bi
Topics: Adult; Aged; CD4-CD8 Ratio; Cell Differentiation; Cytokines; Epidermal Cells; Female; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Male; Middle Aged; Psoriasis; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Th1 Cells; Tumor Necrosis Factor-alpha | 1999 |
Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene.
Topics: Dinitrochlorobenzene; Endothelium, Vascular; Fibroblasts; Humans; Immunohistochemistry; Inflammation Mediators; Interferon-gamma; Interleukin-18; Keratinocytes; Lipopolysaccharides; Melanocytes; Psoriasis; RNA, Messenger; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines.
Topics: Adult; Autoantigens; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokine CXCL10; Chemokines; Chemokines, CXC; Chemotaxis, Leukocyte; Cytokines; Dermatitis, Atopic; Female; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-4; Interleukin-8; Keratinocytes; Leukocytes; Male; Middle Aged; Psoriasis; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A.
Topics: Biological Transport; Calcineurin; Calcineurin Inhibitors; Carcinogens; Cell Differentiation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cyclophilin A; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Humans; Immunosuppressive Agents; Ionomycin; Ionophores; Keratinocytes; NFATC Transcription Factors; Nuclear Proteins; Psoriasis; Signal Transduction; Skin; Tacrolimus; Tacrolimus Binding Protein 1A; Tetradecanoylphorbol Acetate; Transcription Factors | 2002 |
The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor.
Topics: Antibodies, Monoclonal; Calcimycin; Epidermal Growth Factor; Epidermis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Keratinocytes; Precipitin Tests; Protein Kinases; Psoriasis; Receptors, Cell Surface; Receptors, Somatomedin; Tetradecanoylphorbol Acetate | 1992 |
The antipsoriatic drug, anthralin, inhibits protein kinase C--implications for its mechanism of action.
Topics: Animals; Anthralin; In Vitro Techniques; Male; Neutrophils; Protein Kinase C; Psoriasis; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1992 |
[Effect of the dry distillation tar of delipidated soybean (Glyteer) on a psoriasic model in the mouse (4)].
Topics: Animals; Dermatologic Agents; Disease Models, Animal; Edema; Glycine max; Hyperplasia; Male; Mice; Proteins; Psoriasis; Skin; Tars; Tetradecanoylphorbol Acetate | 1992 |
Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes.
Topics: Blotting, Northern; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Cytokines; DNA; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Gene Expression; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-8; Keratinocytes; Lymphocyte Function-Associated Antigen-1; Neutrophils; Precipitin Tests; Psoriasis; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Inflammation of guinea pig dermis. Effects of leukotriene B4 receptor antagonist, SC-41930.
Topics: Administration, Cutaneous; Animals; Benzopyrans; Calcimycin; Disease Models, Animal; Guinea Pigs; Inflammation; Male; Psoriasis; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; Tetradecanoylphorbol Acetate | 1990 |
Increased phospholipase C-catalyzed hydrolysis of phosphatidylinositol-4,5-bisphosphate and 1,2-sn-diacylglycerol content in psoriatic involved compared to uninvolved and normal epidermis.
Topics: Adult; Biopsy; Diglycerides; Epidermal Cells; Epidermis; Humans; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protease Inhibitors; Psoriasis; Reference Values; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Cellular reactivity of polymorphonuclear leukocytes in psoriasis and atopic dermatitis--measurement of lucigenin-dependent chemiluminescence.
Topics: Acridines; Adult; Complement C5; Complement C5a; Dermatitis, Atopic; Dipeptides; Female; Humans; Luminescent Measurements; Male; Middle Aged; Neutrophils; Oxygen; Psoriasis; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Neutrophil function in psoriasis: effects of retinoids.
Topics: Acitretin; Dermatologic Agents; Etretinate; Female; Humans; In Vitro Techniques; Isotretinoin; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Psoriasis; Retinoids; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Inhibition of epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid cells following psoralen/ultraviolet light treatment.
Topics: Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Psoriasis; PUVA Therapy; Tetradecanoylphorbol Acetate | 1989 |
Reactive oxygen species production in circulating polymorphonuclear leukocytes in psoriasis.
Topics: Adult; Aged; Chronic Disease; Female; Humans; Luminescent Measurements; Male; Middle Aged; Neutrophils; Psoriasis; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
[Increase in chemiluminescence induced by receptor-independent stimulation of polymorphonuclear cells from psoriatic patients].
Topics: Adult; Female; Humans; Latex; Luminescent Measurements; Male; Middle Aged; Neutrophils; Oxygen Consumption; Psoriasis; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Phorbol ester decreases cytosolic retinoic acid binding protein (CRABP) capacity in normal but not psoriatic epidermis.
Topics: Adenosine Triphosphate; Binding, Competitive; Carrier Proteins; Cytosol; Epidermis; Humans; Phorbol Esters; Protein Binding; Psoriasis; Receptors, Retinoic Acid; Tetradecanoylphorbol Acetate; Tretinoin | 1988 |
Effect of forskolin on beta-adrenergic hyporesponsiveness in skin.
Topics: Animals; Colforsin; Cyclic AMP; Female; Isoproterenol; Keratinocytes; Mice; Mice, Inbred C3H; Psoriasis; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1988 |
Protein kinase C in normal and psoriatic adult human epidermis.
Topics: Adult; Enzyme Activation; Humans; In Vitro Techniques; Protein Kinase C; Psoriasis; Skin; Tetradecanoylphorbol Acetate | 1987 |
Stimulus-dependent increased generation of oxygen intermediates in monocytes and polymorphonuclear leukocytes in psoriasis.
Topics: Adolescent; Adult; Aged; Concanavalin A; Female; Humans; Luminescent Measurements; Male; Middle Aged; Monocytes; Neutrophils; Oxygen; Psoriasis; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
[Changes in the chemoluminescence behavior of micro- and macrophages in psoriasis: more than just an epiphenomenon?].
Topics: Adolescent; Adult; Aged; Complement C3b; Concanavalin A; Female; Humans; Immunoglobulins; Luminescent Measurements; Macrophages; Male; Middle Aged; Neutrophils; Psoriasis; Tetradecanoylphorbol Acetate; Zymosan | 1985 |